@prefix p: <http://www.wikidata.org/prop/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix schema1: <http://schema.org/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix wd: <http://www.wikidata.org/entity/> .
@prefix wds: <http://www.wikidata.org/entity/statement/> .
@prefix wdt: <http://www.wikidata.org/prop/direct/> .
@prefix wdtn: <http://www.wikidata.org/prop/direct-normalized/> .
@prefix wikibase: <http://wikiba.se/ontology#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

wd:Q417149 rdfs:label "اختزال ثنائي هيدروالفولات"@ar,
        "Дихидрофолатредуктаза"@bg,
        "Dihidrofolat-reduktaza"@bs,
        "Dihydrofolatreduktase"@de,
        "dihydrofolate reductase"@en,
        "Dihidrofolato reductasa"@es,
        "آنزیم احیاء دی هیدروفولات"@fa,
        "Dihydrofolate réductase"@fr,
        "Dihidrofolato redutase"@gl,
        "דיהידרופולאט רדוקטאז"@he,
        "Diidrofolato reduttasi"@it,
        "ジヒドロ葉酸レダクターゼ"@ja,
        "Dihydrofolat reduktase"@nb,
        "Dihydrofolate reductase"@nl,
        "dihydrofolatreduktase"@nn,
        "Dihidrofolato redutase"@pt,
        "дигидрофолат редуктаза"@ru,
        "Dihidrofolat reduktaza"@sh,
        "dihidrofolat reduktaza"@sl,
        "Dihidrofolat reduktaza"@sr,
        "DHFR"@uk,
        "二氢叶酸还原酶"@zh,
        "二氢叶酸还原酶"@zh-cn,
        "二氢叶酸还原酶"@zh-hans,
        "二氫葉酸還原酶"@zh-hant,
        "二氫葉酸還原酶"@zh-hk,
        "二氢叶酸还原酶"@zh-sg,
        "二氫葉酸還原酶"@zh-tw ;
    schema1:dateModified "2026-10-06T19:09:21+00:00"^^xsd:dateTime ;
    schema1:description "protèin"@ace,
        "بروتين في الإنسان العاقل"@ar,
        "Protein"@de,
        "mammalian protein found in Homo sapiens"@en,
        "enzyme"@fr,
        "סוג של אנזים"@he,
        "protein"@id,
        "enzima"@it,
        "menselijk eiwit"@nl,
        "mammalsk protein hos arten Homo sapiens"@nn,
        "proteinë"@sq,
        "protein"@sv,
        "білок людини"@uk ;
    schema1:version 2554103020 ;
    wikibase:identifiers 79 ;
    wikibase:sitelinks 19 ;
    wikibase:statements 128 ;
    skos:altLabel "EC 1.5.1.3"@bg,
        "DHFR"@de,
        "Dihydrofolat-Reduktase"@de,
        "Dihydrofolsäure-Reduktase"@de,
        "Dihydrofolsäurereduktase"@de,
        "DHFR"@en,
        "uniprot:P00374"@en,
        "آنزیم احیا دی هیدروفولات"@fa,
        "انزیم احیا دی هیدروفولات"@fa,
        "انزیم احیاء دی هیدروفولات"@fa,
        "DHFR"@fr,
        "Dihydrofolatereductase"@fr,
        "DHFR"@he,
        "ジヒドロ葉酸還元酵素"@ja,
        "テトラヒドロ葉酸デヒドロゲナーゼ"@ja,
        "Dihydrofolatreduktase"@nb,
        "Dihydrofolaatreductase"@nl,
        "DHFR"@nn,
        "uniprot:P00374"@nn,
        "Дигидрофолат-редуктаза"@ru,
        "Дигидрофолатредуктаза"@ru,
        "DHFR"@zh ;
    p:P10283 wds:Q417149-AF2AB04F-A643-4ED8-99E0-7DB16BA0E60F ;
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        wds:Q417149-6107A1DD-06F5-4357-8058-E25C5847938E,
        wds:Q417149-6B2808B3-A4FC-4B60-8A12-68219C7F38A1,
        wds:Q417149-801B0FC9-5C8D-4172-9588-0ADA3364DA2C,
        wds:Q417149-E9FFC782-0B36-4D84-9846-9D76AD0DCC14 ;
    p:P18 wds:Q417149-248b843a-4b0a-b9fb-5c13-3f1ffc695807 ;
    p:P231 wds:Q417149-fa3c69fd-496d-2267-6ca5-52a628771eb5 ;
    p:P2888 wds:Q417149-3D91751A-1CC7-4F5B-95BC-CB1D9547A6DF ;
    p:P31 wds:Q417149-79745C24-CFD4-4A60-860E-29B0D3947367 ;
    p:P3417 wds:Q417149-5FDFD503-A2F7-4D9E-84F9-7953CFB614AC ;
    p:P352 wds:q417149-31A13887-982C-403E-904F-46BD6DF6AD7C ;
    p:P361 wds:Q417149-11AC2D35-F098-4EF5-8204-822986D42263,
        wds:Q417149-7D21276D-CED3-4AD8-8252-DE5F1AE01A52,
        wds:Q417149-CB70695C-E5D8-441D-B9E4-AC0BF476E946 ;
    p:P527 wds:Q417149-8AE32B9A-5E51-48F1-AE0B-ACD76CB797D5,
        wds:Q417149-DE9F951D-E091-42DB-AAF2-A99505A2C936 ;
    p:P591 wds:Q417149-499c9f72-4a5b-b6cc-3ade-002573268db3,
        wds:Q417149-9d0fafd2-48b7-c6b9-6314-4c2b09523dc6 ;
    p:P6366 wds:Q417149-8B50D6BE-803A-4514-926A-1B2EDA9CB3F7,
        wds:Q417149-A81F941A-8A3E-490A-9114-D61D67CC2D26 ;
    p:P637 wds:Q417149-05AE1280-170C-4176-A4ED-892E91435EEE,
        wds:Q417149-05D649D1-74B4-4FE6-B6DA-439497FAA843,
        wds:Q417149-3C14EC6F-1853-4E2F-AD1F-E67F179E9E4B ;
    p:P638 wds:Q417149-0E120E0C-9C20-48CD-89A5-A848BF4BAA6A,
        wds:Q417149-11EC77CE-6AA8-4BB8-9FFD-8BE3CBD604A0,
        wds:Q417149-30A1DDA0-3098-4032-98CA-BDE2206E88EB,
        wds:Q417149-45533148-DB52-40FB-B4B8-9CB400166725,
        wds:Q417149-5F226424-8B5F-41ED-A5EE-70364AB607D4,
        wds:Q417149-7D489AA5-5EC9-4523-9214-672CF4F8DB05,
        wds:Q417149-B1DFC7BF-4874-461E-B596-7989CD5CEE4E,
        wds:Q417149-C9824E65-610C-406F-8FD2-AFBD0570A16F,
        wds:Q417149-DD80EE97-394D-45CA-BE31-9AC6B1811F19,
        wds:Q417149-E2BECB13-B7CC-44C4-9439-C186C2E6618B,
        wds:Q417149-E75DB789-553C-4601-BE0C-E21208DDF0A4,
        wds:q417149-03B13CD2-AF29-4366-A5B0-C23990D574F1,
        wds:q417149-0438C537-0A7A-453C-8A1E-56FD473E6CFF,
        wds:q417149-06117137-3561-4FF7-9149-45DA4280F2E9,
        wds:q417149-0CE941A8-99CF-44B1-A532-C411A56BA624,
        wds:q417149-0E53DBD3-3AED-4B54-B5D6-E25EB6E3CC80,
        wds:q417149-105A9579-E88F-4A4C-8918-DA1092B8B176,
        wds:q417149-12708D38-1481-4FB4-AA46-83E253328203,
        wds:q417149-17101046-CFA5-4DB5-AFB3-D917F7B1C2DD,
        wds:q417149-1EC54DBB-4329-4E92-A315-6F1FF5C2B760,
        wds:q417149-216C3C66-3163-4BE9-9BF5-654A00D8EBE3,
        wds:q417149-287D1829-58E0-4DF3-93EA-46178A59BA17,
        wds:q417149-2925F7D9-25FE-4C0B-ADFD-80A1ECA81BC9,
        wds:q417149-2A516640-14B8-4710-8CA6-554D9EFAE4C3,
        wds:q417149-3347B5B5-4626-4117-9685-796D0FC55801,
        wds:q417149-3770064F-14F7-43BD-B25C-FB07F6091A26,
        wds:q417149-3C6F0A13-1033-446A-8712-836FE843873B,
        wds:q417149-3EF9FB2F-EC8F-4541-A387-C44EEB958F38,
        wds:q417149-4403AC7E-57E6-410D-A681-A85C76FA5717,
        wds:q417149-477AAD8E-1565-4493-AF6B-169978F45B65,
        wds:q417149-53333F39-32CD-4B73-8BFA-040DE8E8437D,
        wds:q417149-57A30AA1-BBA3-4AEB-B774-7976380D0DF2,
        wds:q417149-5C4D4755-4108-4BA4-A0EC-C017D2933E81,
        wds:q417149-62E543F0-E6A2-4737-AC96-FC88D9F23C8B,
        wds:q417149-677503C1-3C5A-406A-B23D-2AE5588285F7,
        wds:q417149-680AC380-0878-4D5D-A3E0-735F2D95F328,
        wds:q417149-6F3A314C-9D97-4492-A85A-8945DB703B5A,
        wds:q417149-73ECB3A4-3662-4AC7-AD15-FA3E339714BA,
        wds:q417149-775F31A5-873A-444E-B39E-D53D472DF15C,
        wds:q417149-78EFC520-77A4-432E-B6CF-7E4A951A7959,
        wds:q417149-7903379A-0589-4C54-919D-975F02B51CE6,
        wds:q417149-7BD81637-19D4-4A7D-BFD2-6ED1BFF8C113,
        wds:q417149-7FAD22F0-A8D2-4A2D-ABAC-B5519B349FE6,
        wds:q417149-8B1E418A-4758-4511-A879-1D8C24E1BF0E,
        wds:q417149-8B842E3F-7B56-44D1-9CFA-7DF4001843C3,
        wds:q417149-9F072C63-AD70-405A-AC48-27EAA29DE71F,
        wds:q417149-A00FCFF7-530B-4A9D-AED8-F57478264FE6,
        wds:q417149-AD5F78B0-6966-44E9-8380-A43D52556606,
        wds:q417149-BCAA183B-06A9-4C07-984F-3E9F1A8E3053,
        wds:q417149-BCE35BE7-4D6C-4151-A8AB-CE3D4759DBE1,
        wds:q417149-BE3E6D52-5735-4950-A918-2553DB2A77FC,
        wds:q417149-C71F0A69-02FF-4D99-880D-AA97C7E5C993,
        wds:q417149-D0435743-59F1-4DB7-8082-DF644C83AD62,
        wds:q417149-D0B708B3-665D-45F7-ACFE-F23EFEB8044B,
        wds:q417149-D62F0267-FF98-47EA-95FC-D87613DCD489,
        wds:q417149-D6B4D2DE-B392-4330-B5A8-994F90933133,
        wds:q417149-DB56AE03-9101-48DD-B05C-F9CDB7DC8597,
        wds:q417149-E0C8CED6-BDBC-4451-81F8-D05E1C588382,
        wds:q417149-E6FE432A-4E98-4441-BD16-78016FD97A90,
        wds:q417149-E77B21D4-FA9C-4038-8EA0-515DCA970BB5,
        wds:q417149-EBBDF981-5E42-46DC-A67B-477211614EEC,
        wds:q417149-F22DD86E-90BD-4563-9C08-3777A21BE4D1,
        wds:q417149-F919F635-8735-4E6F-AC9F-C07C64B103FE,
        wds:q417149-FA62B26E-BA74-42AA-B20A-89A0972D4296,
        wds:q417149-FBB32E8E-91E1-42B6-856E-A722154B79D5 ;
    p:P646 wds:Q417149-9CF123C4-EED9-4B72-8AD4-F8D36892F26C ;
    p:P680 wds:Q417149-27D6F93C-7F5C-426D-A3E2-F2188654748C,
        wds:Q417149-28FEBC82-6744-4342-A712-F341AB8A8901,
        wds:Q417149-3FC3DA9B-1F0C-435F-A0F4-0C614FD8A9F2,
        wds:Q417149-404413FF-3983-4FCD-A532-839578F6F8FD,
        wds:Q417149-4611E140-6EA8-4E22-82AC-EF7FE3B3F434,
        wds:Q417149-50D3E369-A6B5-40D8-A015-DC15933346A4,
        wds:Q417149-581BC871-9E62-4290-8E0E-0ED12D51971F,
        wds:Q417149-6896AA3C-12C4-4859-88AB-14875D192890,
        wds:Q417149-772D1B80-E3E1-4571-9052-E46766D1F0F5,
        wds:Q417149-C9E1C39E-56FF-461A-B85F-B47DC87CCA31,
        wds:Q417149-E53FE3F9-56F8-4239-B0DE-FBC7B2B2BCDA,
        wds:Q417149-ECC9E310-8307-49DA-B81E-77B07D8208DD ;
    p:P681 wds:Q417149-56C13729-2A5A-406E-A301-992B1177568E,
        wds:Q417149-8148EDF4-3C0E-4FD7-9A57-0C4E2BC3C272,
        wds:Q417149-CF767B43-F5F9-4336-93BE-AF000B1C0830,
        wds:Q417149-E4B25D82-3EEE-446C-AE93-7C99772907C1,
        wds:Q417149-EE67173D-5B59-474C-98F4-1C0D4B2FD123 ;
    p:P682 wds:Q417149-09279B39-1714-46AE-BF38-28A0039EC3C8,
        wds:Q417149-138BE8D5-3D19-4CC6-8ADC-130E59FC67DE,
        wds:Q417149-1ADC6C56-F6C1-402B-B319-0CA0FFB3D20E,
        wds:Q417149-2C76F385-49E4-4C8A-AC48-FD9D1ADDE166,
        wds:Q417149-3761B1DC-DA5F-4C74-A032-53812A8235F0,
        wds:Q417149-57636C2C-A931-42B1-9478-91229DE3EB57,
        wds:Q417149-5DB905A3-0B42-4105-BED6-4500E4008FB3,
        wds:Q417149-5EF6CF28-0BE1-43DB-9DCF-779BDC6CCCBD,
        wds:Q417149-75D44FB1-62EA-4249-9100-6F5B2512102A,
        wds:Q417149-9295BC15-0122-43AD-B0F5-DE5D160CD1E9,
        wds:Q417149-C42D0151-36CC-419B-8C4F-B4ADD398D97B,
        wds:Q417149-C82B5F32-416F-40E1-87BE-70F15C315142,
        wds:Q417149-DEE513F4-04C4-421C-B04E-A4210C231EB5,
        wds:Q417149-E45BEB8A-8946-4B79-A205-A3F7E32CE66D,
        wds:Q417149-FD314C81-8A12-4C97-B2EE-29172775ECCF ;
    p:P702 wds:q417149-707D8462-5840-497B-8AC2-2701110C0FE7 ;
    p:P703 wds:Q417149-568DBC13-3686-4C20-B549-919DB7F3AD00 ;
    p:P705 wds:Q417149-BAE8AB11-79A1-40E8-8CCA-4D695CFB0B68,
        wds:q417149-42ED84EC-E392-4B7D-B5CC-8DAB71D48D06,
        wds:q417149-ED85646E-7102-4207-92FE-CE702DA87147,
        wds:q417149-F915FD73-07B8-4C99-8334-493D559D9A59 ;
    wdtn:P352 <http://purl.uniprot.org/uniprot/P00374> ;
    wdtn:P6366 <https://makg.org/entity/2781320022>,
        <https://makg.org/entity/2909764806> ;
    wdtn:P637 <http://purl.uniprot.org/refseq/NP_000782>,
        <http://purl.uniprot.org/refseq/NP_001277283>,
        <http://purl.uniprot.org/refseq/NP_001277286> ;
    wdtn:P638 <https://rdf.wwpdb.org/pdb/1BOZ>,
        <https://rdf.wwpdb.org/pdb/1DHF>,
        <https://rdf.wwpdb.org/pdb/1DLR>,
        <https://rdf.wwpdb.org/pdb/1DLS>,
        <https://rdf.wwpdb.org/pdb/1DRF>,
        <https://rdf.wwpdb.org/pdb/1HFP>,
        <https://rdf.wwpdb.org/pdb/1HFQ>,
        <https://rdf.wwpdb.org/pdb/1HFR>,
        <https://rdf.wwpdb.org/pdb/1KMS>,
        <https://rdf.wwpdb.org/pdb/1KMV>,
        <https://rdf.wwpdb.org/pdb/1MVS>,
        <https://rdf.wwpdb.org/pdb/1MVT>,
        <https://rdf.wwpdb.org/pdb/1OHJ>,
        <https://rdf.wwpdb.org/pdb/1OHK>,
        <https://rdf.wwpdb.org/pdb/1PD8>,
        <https://rdf.wwpdb.org/pdb/1PD9>,
        <https://rdf.wwpdb.org/pdb/1PDB>,
        <https://rdf.wwpdb.org/pdb/1S3U>,
        <https://rdf.wwpdb.org/pdb/1S3V>,
        <https://rdf.wwpdb.org/pdb/1S3W>,
        <https://rdf.wwpdb.org/pdb/1U71>,
        <https://rdf.wwpdb.org/pdb/1U72>,
        <https://rdf.wwpdb.org/pdb/1YHO>,
        <https://rdf.wwpdb.org/pdb/2C2S>,
        <https://rdf.wwpdb.org/pdb/2C2T>,
        <https://rdf.wwpdb.org/pdb/2DHF>,
        <https://rdf.wwpdb.org/pdb/2W3A>,
        <https://rdf.wwpdb.org/pdb/2W3B>,
        <https://rdf.wwpdb.org/pdb/2W3M>,
        <https://rdf.wwpdb.org/pdb/3EIG>,
        <https://rdf.wwpdb.org/pdb/3F8Y>,
        <https://rdf.wwpdb.org/pdb/3F8Z>,
        <https://rdf.wwpdb.org/pdb/3F91>,
        <https://rdf.wwpdb.org/pdb/3FS6>,
        <https://rdf.wwpdb.org/pdb/3GHC>,
        <https://rdf.wwpdb.org/pdb/3GHV>,
        <https://rdf.wwpdb.org/pdb/3GHW>,
        <https://rdf.wwpdb.org/pdb/3GI2>,
        <https://rdf.wwpdb.org/pdb/3GYF>,
        <https://rdf.wwpdb.org/pdb/3L3R>,
        <https://rdf.wwpdb.org/pdb/3N0H>,
        <https://rdf.wwpdb.org/pdb/3NTZ>,
        <https://rdf.wwpdb.org/pdb/3NU0>,
        <https://rdf.wwpdb.org/pdb/3NXO>,
        <https://rdf.wwpdb.org/pdb/3NXR>,
        <https://rdf.wwpdb.org/pdb/3NXT>,
        <https://rdf.wwpdb.org/pdb/3NXV>,
        <https://rdf.wwpdb.org/pdb/3NXX>,
        <https://rdf.wwpdb.org/pdb/3NXY>,
        <https://rdf.wwpdb.org/pdb/3NZD>,
        <https://rdf.wwpdb.org/pdb/3OAF>,
        <https://rdf.wwpdb.org/pdb/3S3V>,
        <https://rdf.wwpdb.org/pdb/3S7A>,
        <https://rdf.wwpdb.org/pdb/4DDR>,
        <https://rdf.wwpdb.org/pdb/4G95>,
        <https://rdf.wwpdb.org/pdb/4KAK>,
        <https://rdf.wwpdb.org/pdb/4KBN>,
        <https://rdf.wwpdb.org/pdb/4KD7>,
        <https://rdf.wwpdb.org/pdb/4KEB>,
        <https://rdf.wwpdb.org/pdb/4KFJ>,
        <https://rdf.wwpdb.org/pdb/4M6J>,
        <https://rdf.wwpdb.org/pdb/4M6K>,
        <https://rdf.wwpdb.org/pdb/4M6L>,
        <https://rdf.wwpdb.org/pdb/4QHV>,
        <https://rdf.wwpdb.org/pdb/4QJC> ;
    wdt:P10283 "C2781320022" ;
    wdt:P129 wd:Q126677485,
        wd:Q27088402,
        wd:Q415220,
        wd:Q422232,
        wd:Q637059 ;
    wdt:P18 <http://commons.wikimedia.org/wiki/Special:FilePath/PDB%208dfr%20EBI.jpg> ;
    wdt:P231 "9002-03-3" ;
    wdt:P2888 <http://purl.uniprot.org/uniprot/P00374> ;
    wdt:P31 wd:Q8054 ;
    wdt:P3417 "Dhfr" ;
    wdt:P352 "P00374" ;
    wdt:P361 wd:Q24726779,
        wd:Q83146156,
        wd:Q95350644 ;
    wdt:P527 wd:Q24777272,
        wd:Q24778209 ;
    wdt:P591 "1.5.1.3" ;
    wdt:P6366 "2781320022",
        "2909764806" ;
    wdt:P637 "NP_000782",
        "NP_001277283",
        "NP_001277286" ;
    wdt:P638 "1BOZ",
        "1DHF",
        "1DLR",
        "1DLS",
        "1DRF",
        "1HFP",
        "1HFQ",
        "1HFR",
        "1KMS",
        "1KMV",
        "1MVS",
        "1MVT",
        "1OHJ",
        "1OHK",
        "1PD8",
        "1PD9",
        "1PDB",
        "1S3U",
        "1S3V",
        "1S3W",
        "1U71",
        "1U72",
        "1YHO",
        "2C2S",
        "2C2T",
        "2DHF",
        "2W3A",
        "2W3B",
        "2W3M",
        "3EIG",
        "3F8Y",
        "3F8Z",
        "3F91",
        "3FS6",
        "3GHC",
        "3GHV",
        "3GHW",
        "3GI2",
        "3GYF",
        "3L3R",
        "3N0H",
        "3NTZ",
        "3NU0",
        "3NXO",
        "3NXR",
        "3NXT",
        "3NXV",
        "3NXX",
        "3NXY",
        "3NZD",
        "3OAF",
        "3S3V",
        "3S7A",
        "4DDR",
        "4G95",
        "4KAK",
        "4KBN",
        "4KD7",
        "4KEB",
        "4KFJ",
        "4M6J",
        "4M6K",
        "4M6L",
        "4QHV",
        "4QJC" ;
    wdt:P646 "/m/0pys4" ;
    wdt:P680 wd:Q14330639,
        wd:Q14349613,
        wd:Q14349632,
        wd:Q14633859,
        wd:Q14819371,
        wd:Q14864131,
        wd:Q14876919,
        wd:Q21107375,
        wd:Q21115691,
        wd:Q22315373,
        wd:Q22319812 ;
    wdt:P681 wd:Q220599,
        wd:Q39572,
        wd:Q5058355,
        wd:Q79899 ;
    wdt:P682 wd:Q14633894,
        wd:Q14761967,
        wd:Q14819379,
        wd:Q14819383,
        wd:Q14819384,
        wd:Q14819386,
        wd:Q14819388,
        wd:Q14863402,
        wd:Q14864571,
        wd:Q14864920,
        wd:Q14884978,
        wd:Q14902236 ;
    wdt:P702 wd:Q14819367 ;
    wdt:P703 wd:Q15978631 ;
    wdt:P705 "ENSP00000396308",
        "ENSP00000421334",
        "ENSP00000422732",
        "ENSP00000426474" .