Transformation related protein 53

mammalian protein found in Mus musculus
rdfs:label
"Transformation related protein 53"@en
skos:altLabel "ME-delta123p53"@en
"Trp53"@en
"cellular tumor antigen p53"@en
"mutant p53"@en
"p53 cellular tumor antigen"@en
"tumor suppressor p53"@en
"tumor supressor p53"@en
schema:description
"mammalian protein found in Mus musculus"@en
schema:dateModified "2025-11-06T14:44:17+00:00"^^xsd:dateTime
schema:version 2426562362
wikibase:identifiers 15
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wd:statement/Q14818136-6C71E66F-17BB-4138-BB71-09343327BA92
wd:statement/Q14818136-6CC649C1-6E51-495A-9FB2-A1B1F4FE6B36
wd:statement/Q14818136-6E5AA32D-05A4-4C78-9560-05592ACA4966
wd:statement/Q14818136-74F000E5-85BC-4F7B-BC5F-2BB6E53DD98B
wd:statement/Q14818136-758F69A9-3009-48FF-A5F2-5D9B7F58822C
wd:statement/Q14818136-779BE32E-95B8-492D-A93A-3F4EE7F44677
wd:statement/Q14818136-77E43F37-5172-4929-9D02-E3AE983620C4
wd:statement/Q14818136-7830082E-7172-433A-B1A0-DA19CFD3FF27
wd:statement/Q14818136-78B3048C-D46B-445F-9C90-A4107B0C2904
wd:statement/Q14818136-7BAB0C82-E10F-4C07-BAB6-1C0F445E7851
wd:statement/Q14818136-7BD2BCCB-661A-4C18-9554-F3401013915A
wd:statement/Q14818136-7D4B7D1A-F292-4554-9F4E-C7E9024F077D
wd:statement/Q14818136-7DE260C9-A4C9-4A35-A62C-23D104B45030
wd:statement/Q14818136-7E5CB0CC-C426-4E3F-8550-D3041B137EB6
wd:statement/Q14818136-7F0C83A6-5631-4AE9-8E9C-7534AEB1A8FA
wd:statement/Q14818136-7F5E06CF-AC28-4694-B24C-8F73C03912BC
wd:statement/Q14818136-7FA65B7F-8489-404F-BD42-3B9B280D61BA
wd:statement/Q14818136-809166AF-E50C-4094-8496-ED3D846D13A4
wd:statement/Q14818136-80A02AD2-AAD0-462D-B6A8-499B60003FA6
wd:statement/Q14818136-80EAAF91-EBF6-4D7F-A090-0C3A53B68600
wd:statement/Q14818136-80F1B42D-A4BA-4B8F-B25A-28A6048458CC
wd:statement/Q14818136-81C0B8F7-F4AA-4B15-91BE-2414115FACC5
wd:statement/Q14818136-830F392C-4BC6-4CA7-9EF2-4143EF76BF60
wd:statement/Q14818136-844353AD-B3CC-4DCA-807B-EFF56B9466DD
wd:statement/Q14818136-8451135A-47F4-460B-BE32-48A6F7DB7C01
wd:statement/Q14818136-84D86543-D06A-4B8C-B775-36EF1D21A4DD
wd:statement/Q14818136-8566ECC9-8BE8-4361-AFE8-436824795DF8
wd:statement/Q14818136-85E00902-84D8-4ED8-AA2F-CE4ED815AF4D
wd:statement/Q14818136-875AC2E8-4BE0-4B6D-94A2-45926A07DE18
wd:statement/Q14818136-87E14032-643A-4209-B645-39229EB2002B
wd:statement/Q14818136-89BA1AAF-4161-474D-8DD6-78DCE85A40FD
wd:statement/Q14818136-8A06425F-AF50-4377-AF61-50BC5F2517D6
wd:statement/Q14818136-8B2F3398-325F-4401-8A20-8080F86D0C46
wd:statement/Q14818136-8CF95CE1-7133-44C4-9492-CAFC5ACE5EEC
wd:statement/Q14818136-8D132597-96E5-4E0B-AFEE-85FA97F814FD
wd:statement/Q14818136-8D17EC0B-0ACF-4BDC-98EA-5368786C91CD
wd:statement/Q14818136-8F17DE18-74A6-4DFC-A3F0-AAE45FB8FCB8
wd:statement/Q14818136-95542398-8FC8-4CDD-AF8C-ACAE280897E5
wd:statement/Q14818136-96F70B1F-7782-4C1C-A8AF-C58E04DA77F2
wd:statement/Q14818136-97526DF5-1880-42AB-B8E8-55F842E99754
wd:statement/Q14818136-97B915CE-FE88-4CDB-960A-BBDCC467005D
wd:statement/Q14818136-990F88AF-9877-4D35-8628-A757F6C372A3
wd:statement/Q14818136-99B03E9B-6E59-4403-AEDF-84D6FFEE3B78
wd:statement/Q14818136-9A7E47E9-65ED-463F-88FA-8DAB7B1B885C
wd:statement/Q14818136-9C1D774A-2D6B-48A7-BACE-4605C13837A9
wd:statement/Q14818136-9D27D3E5-D082-4A52-B056-F00025998F0D
wd:statement/Q14818136-9FF67FE7-3B5C-425C-9F09-84EF1F9DC4D4
wd:statement/Q14818136-9FFD8478-92DC-4C5A-8BA2-119860F81B8B
wd:statement/Q14818136-A02EC280-7D45-44F5-BBDC-875FDF06FBEC
wd:statement/Q14818136-A064B674-D270-4E9B-96E0-8822B3FA67FB
wd:statement/Q14818136-A20B6CC8-477B-45E6-AB2F-F11D38EA0270
wd:statement/Q14818136-A583A8DD-2C4C-44F7-9156-4D8BF0EAE908
wd:statement/Q14818136-AE2F774F-9113-4C8F-B565-0E883B4702BB
wd:statement/Q14818136-AEF3B557-6F06-426A-A592-EF2007A065AE
wd:statement/Q14818136-AF0995E0-B89A-4F0E-B383-603B545CD88A
wd:statement/Q14818136-B02270C9-1F77-4FD7-9C26-1856FA486E1C
wd:statement/Q14818136-B11A8AAE-5636-45FF-89BD-B06F9F7A058B
wd:statement/Q14818136-B1AEC551-E4E4-4E59-81D4-94F2BF42C38D
wd:statement/Q14818136-B32015DE-E0EB-46CD-92F7-53842F8BD869
wd:statement/Q14818136-B8B46B1F-660F-4957-AE3F-041E4FEF4C4F
wd:statement/Q14818136-B8BCD176-AB4A-4EA6-8EB7-8A215B29B0DA
wd:statement/Q14818136-BB405B3D-9814-4C9B-B449-57B3CE46E8A6
wd:statement/Q14818136-BD33B0E0-692D-4EE9-AC75-9850AFEB0FD4
wd:statement/Q14818136-BE752B0B-202C-49B1-8A7F-3E36FE27F182
wd:statement/Q14818136-BE984A43-D136-42B5-88D0-513D9169DB94
wd:statement/Q14818136-BF12ACD0-9B14-48F4-91AD-49236DCE6F80
wd:statement/Q14818136-C053F663-7734-4DB9-BA64-A65ADF2E6E0A
wd:statement/Q14818136-C31C70C8-CF18-490D-9FEA-21ADF3ABEE76
wd:statement/Q14818136-C46F1868-7738-4006-B660-AF860D79D80A
wd:statement/Q14818136-C5631D0F-75F4-422A-AD9D-CA413CB5E8FA
wd:statement/Q14818136-C7538121-E767-46F6-B2B6-4F587CCC3EBD
wd:statement/Q14818136-C7798A06-24FE-42A5-A8C9-FF195BDC1FC4
wd:statement/Q14818136-C7D16797-DFAB-40E9-89E1-649A007D93CC
wd:statement/Q14818136-C8E02A69-84B8-4803-91CA-8D83356BF156
wd:statement/Q14818136-C92FBEE0-F641-441E-81B6-F89B8BC84216
wd:statement/Q14818136-C93D765C-EDB1-4873-8E9C-ADB9D3331894
wd:statement/Q14818136-C95D020E-2132-40CB-9BB1-F4B170881A08
wd:statement/Q14818136-C96C51B7-3746-4B1F-B9F0-C98F542CEA67
wd:statement/Q14818136-CAE2AD71-E43D-4E15-8C71-F0573440C4D1
wd:statement/Q14818136-CB4E1354-F501-4E52-AB3A-66DBBD107E93
wd:statement/Q14818136-CB7BB9DE-DEB1-488B-9294-3A108A467C22
wd:statement/Q14818136-CFEDBC22-1C51-4FAC-8C29-24C90E1D854B
wd:statement/Q14818136-D18D9557-648B-4490-BDEA-52BF60023E1E
wd:statement/Q14818136-D4DB9F81-6BDD-4080-A0E4-537896614B02
wd:statement/Q14818136-D6B1774D-3049-4B31-9C27-2B7E4794071A
wd:statement/Q14818136-D7E14B10-042E-4034-B7C3-D3E275087909
wd:statement/Q14818136-D85F7FF4-10BE-4A74-A590-730FAC68A38E
wd:statement/Q14818136-D959D0FD-FEBD-4D28-8AAE-A161781158EB
wd:statement/Q14818136-D978C681-2065-474F-8544-59265C757297
wd:statement/Q14818136-DA2BD579-2787-4C13-8E82-2536C4C086E3
wd:statement/Q14818136-DB26BB87-0280-4B0A-A1D3-9CB8BF7A2F1A
wd:statement/Q14818136-DBE5C75B-78CA-45E9-8796-218D779ECBF1
wd:statement/Q14818136-DE34A602-549D-4B9C-8722-D5670B5960B7
wd:statement/Q14818136-DEE876C2-BBA6-4372-935A-53EC99F45885
wd:statement/Q14818136-DF4CB7CB-6550-46B9-8C17-A29531409A51
wd:statement/Q14818136-DF5CB807-D193-45F0-A787-BCB474903801
wd:statement/Q14818136-E1AECAD9-325E-4ECC-BB09-FBB0AAD9F06E
wd:statement/Q14818136-E1D22207-BFCE-4FEE-8CBD-2FFA6B0369EB
wd:statement/Q14818136-E37BA0DE-0371-4314-A306-1D25F2CB83C0
wd:statement/Q14818136-E388F1F0-F6E4-490A-B0A2-869FD1E6152C
wd:statement/Q14818136-E53C5562-A694-4EA6-8B11-C3BC35B6A64D
wd:statement/Q14818136-E690B878-06D3-4AE9-92A5-0F321D2B0758
wd:statement/Q14818136-E7C8BAC4-CF33-4630-9B5A-F8EDD66DAFAE
wd:statement/Q14818136-E7CAA012-D2AE-4AFE-A8ED-F870E684A3DA
wd:statement/Q14818136-E98BE34B-5ACE-4F0C-99E9-7ECC14F101CD
wd:statement/Q14818136-ED030E9D-2C80-46CC-9C45-2D4D7FDBEF58
wd:statement/Q14818136-ED482181-64A4-4EEC-AE79-11F37C41EC1E
wd:statement/Q14818136-EDE2E47D-DD30-4A22-BA2D-F42D515F945D
wd:statement/Q14818136-EF960177-EEF3-4652-B9F4-D8175771ED2B
wd:statement/Q14818136-F12471DF-625D-40F3-AF77-A381CCC06D3A
wd:statement/Q14818136-F130A0B2-38D9-430B-9C1E-8001CEC1ECEF
wd:statement/Q14818136-F274EFC1-B986-42AC-806D-B328E346577B
wd:statement/Q14818136-F5B261D1-3AB5-46C5-8217-8E0F88BA8499
wd:statement/Q14818136-F610E48F-61EF-4870-B3CF-9318CE2B5767
wd:statement/Q14818136-F6E77486-A5D0-48B7-8F11-FC33DE7910D5
wd:statement/Q14818136-F811F071-C442-4C3E-899E-BD1BDA699B33
wd:statement/Q14818136-FABB3313-D1A1-41D1-B446-BFEB741EAD2A
wd:statement/Q14818136-FEBAEFAA-FE2E-4C5B-BFDD-7A2DB69BF17C
p:P702 wd:statement/Q14818136-A0AD907E-FFAD-4C80-9971-708903C9A8B8
p:P703 wd:statement/Q14818136-CBEE2AC5-FA00-4A91-B57F-FBB6838FB55A
p:P705 wd:statement/Q14818136-6C136074-C724-4272-AD66-44D4D7AB8561
wd:statement/Q14818136-D2CF38D2-056F-4558-BEC3-9F4F90D46AAF
wd:statement/Q14818136-E3B2DDC8-1B71-4001-A833-6B7C4A1BC50E
wd:statement/q14818136-B89441CA-91F6-474F-8CC6-AA1719BBA478
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P02340>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_001120705>
<http://purl.uniprot.org/refseq/NP_035770>
<http://purl.uniprot.org/refseq/XP_006533220>
<http://purl.uniprot.org/refseq/XP_030101782>
<http://purl.uniprot.org/refseq/XP_030101783>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1HU8>
<https://rdf.wwpdb.org/pdb/2GEQ>
<https://rdf.wwpdb.org/pdb/2P52>
<https://rdf.wwpdb.org/pdb/3EXJ>
<https://rdf.wwpdb.org/pdb/3EXL>
wdt:P279 protein
wdt:P31 protein
wdt:P352 "P02340"
wdt:P361 p53 tumour suppressor family
p53-like transcription factor, DNA-binding
p53/RUNT-type transcription factor, DNA-binding domain superfamily
p53-like tetramerisation domain superfamily
p53, tetramerisation domain, protein family
p53, DNA-binding domain, protein family
p53 transactivation domain, protein family
wdt:P527 p53, tetramerisation domain
p53, DNA-binding domain
p53 transactivation domain
wdt:P637 "NP_001120705"
"NP_035770"
"XP_006533220"
"XP_030101782"
"XP_030101783"
wdt:P638 "1HU8"
"2GEQ"
"2P52"
"3EXJ"
"3EXL"
wdt:P680 metal ion binding
enzyme binding
DNA binding
ubiquitin protein ligase binding
chaperone binding
protease binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
DNA-binding transcription activator activity, RNA polymerase II-specific
p53 binding
chromatin binding
damaged DNA binding
DNA-binding transcription factor activity
copper ion binding
ATP binding
transcription factor binding
protein kinase binding
receptor tyrosine kinase binding
histone deacetylase regulator activity
histone acetyltransferase binding
protein N-terminus binding
protein phosphatase 2A binding
MDM2/MDM4 family protein binding
protein C-terminus binding
sequence-specific DNA binding
protein phosphatase binding
DNA-binding transcription factor activity, RNA polymerase II-specific
RNA polymerase II transcription regulatory region sequence-specific DNA binding
protein self-association
histone deacetylase binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcription coregulator binding
protein binding
mRNA 3'-UTR binding
TFIID-class transcription factor complex binding
promoter-specific chromatin binding
disordered domain specific binding
wdt:P681 nucleoplasm
transcription factor TFIID complex
nuclear body
PML body
transcription regulator complex
site of double-strand break
chromatin
cytosol
protein-containing complex
replication fork
nucleolus
mitochondrial matrix
intracellular anatomical structure
mitochondrion
nucleus
cytoplasm
endoplasmic reticulum
nuclear matrix
wdt:P682 gastrulation
central nervous system development
positive regulation of peptidyl-tyrosine phosphorylation
apoptotic process
response to oxidative stress
Ras protein signal transduction
protein localization
negative regulation of cell population proliferation
negative regulation of apoptotic process
negative regulation of cell growth
negative regulation of transcription by RNA polymerase II
regulation of transcription, DNA-templated
positive regulation of gene expression
regulation of apoptotic process
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
protein stabilization
multicellular organism development
negative regulation of proteolysis
ER overload response
transcription, DNA-templated
in utero embryonic development
release of cytochrome c from mitochondria
T cell proliferation involved in immune response
B cell lineage commitment
T cell lineage commitment
double-strand break repair
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
transforming growth factor beta receptor signaling pathway
negative regulation of neuroblast proliferation
negative regulation of DNA replication
determination of adult lifespan
rRNA transcription
response to salt stress
response to X-ray
response to gamma radiation
DNA damage response, signal transduction by p53 class mediator
negative regulation of transforming growth factor beta receptor signaling pathway
positive regulation of histone deacetylation
mitotic G1 DNA damage checkpoint signaling
positive regulation of protein oligomerization
T cell differentiation in thymus
cellular response to UV
multicellular organism growth
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
response to antibiotic
negative regulation of fibroblast proliferation
protein tetramerization
chromosome organization
neuron apoptotic process
positive regulation of thymocyte apoptotic process
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
positive regulation of leukocyte migration
response to ischemia
response to UV
embryo development ending in birth or egg hatching
positive regulation of cardiac muscle cell apoptotic process
regulation of tissue remodeling
regulation of cell population proliferation
regulation of neuron apoptotic process
negative regulation of smooth muscle cell proliferation
regulation of intracellular pH
regulation of cell cycle
negative regulation of mitophagy
negative regulation of DNA biosynthetic process
negative regulation of reactive oxygen species metabolic process
protein homotetramerization
response to hyperoxia
negative regulation of gene expression
response to ethanol
cerebellum development
response to retinoic acid
response to organic cyclic compound
regulation of transcription by RNA polymerase II
embryonic organ development
response to cytokine
response to amino acid
response to UV-B
negative regulation of mitotic cell cycle
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
hematopoietic stem cell differentiation
response to organonitrogen compound
rhythmic process
transcription by RNA polymerase II
cellular response to gamma radiation
viral process
response to caffeine
interferon-gamma-mediated signaling pathway
cellular response to heat
protein import into nucleus
response to metal ion
response to vitamin B3
response to inorganic substance
hematopoietic progenitor cell differentiation
cellular response to organonitrogen compound
regulation of mitochondrial membrane permeability involved in apoptotic process
regulation of thymocyte apoptotic process
bone marrow development
cellular response to reactive oxygen species
positive regulation of execution phase of apoptosis
negative regulation of telomerase activity
mRNA transcription
positive regulation of RNA polymerase II transcription preinitiation complex assembly
wound healing
oligodendrocyte apoptotic process
positive regulation of mitochondrial membrane permeability
entrainment of circadian clock by photoperiod
cardiac septum morphogenesis
cell cycle
circadian rhythm
programmed necrotic cell death
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
positive regulation of pri-miRNA transcription by RNA polymerase II
regulation of hydrogen peroxide-induced cell death
regulation of cellular senescence
regulation of DNA damage response, signal transduction by p53 class mediator
regulation of fibroblast apoptotic process
intrinsic apoptotic signaling pathway in response to hypoxia
cellular response to UV-C
regulation of intrinsic apoptotic signaling pathway by p53 class mediator
circadian behavior
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
mitochondrial DNA repair
negative regulation of glucose catabolic process to lactate via pyruvate
RNA polymerase II preinitiation complex assembly
signal transduction by p53 class mediator
positive regulation of transcription from RNA polymerase II promoter in response to stress
negative regulation of production of miRNAs involved in gene silencing by miRNA
positive regulation of production of miRNAs involved in gene silencing by miRNA
cellular response to actinomycin D
protein-containing complex assembly
nucleotide-excision repair
autophagy
programmed cell death
ageing
necroptosis
somitogenesis
development of the heart
positive regulation of programmed necrotic cell death
wdt:P702 Trp53
wdt:P703 house mouse
wdt:P705 "ENSMUSP00000005371"
"ENSMUSP00000104297"
"ENSMUSP00000104298"
"ENSMUSP00000127130"
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