aspartic-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
rdfs:label
"aspartic-type endopeptidase activity"@en
skos:altLabel "GO:0004190"@en
"aspartic endopeptidase activity"@en
schema:description
"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile."@en
schema:dateModified "2026-09-26T17:44:39+00:00"^^xsd:dateTime
schema:version 2549731320
wikibase:identifiers 1
wikibase:sitelinks 0
wikibase:statements 6
p:P279 wd:statement/Q14859567-1960EC3D-608B-409B-B029-C552CDC5537D
wd:statement/Q14859567-54B8E12A-45ED-4CEC-9938-E22B556AE2F1
p:P2888 wd:statement/Q14859567-C2B96800-1F55-44EB-98D2-52143E1CB6FD
p:P31 wd:statement/Q14859567-B66CF686-0F43-44B8-B561-4C308B4F6352
p:P591 wd:statement/Q14859567-E33446DF-AEA2-4047-99DB-A591C75C0796
p:P686 wd:statement/Q14859567-5CFF984D-0B75-4801-B0AA-1307CAD623A7
wdt:P279 endopeptidase activity
aspartic-type peptidase activity
wdt:P2888 <http://purl.obolibrary.org/obo/GO_0004190>
wdt:P31 molecular function
wdt:P591 "3.4.23.-"
wdt:P686 "GO:0004190"
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