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rdfs:label
|
"3-hydroxy-3-methylglutaryl-Coenzyme A reductase"@en
"3-hydroxy-3-methylglutaryl-Coenzyme A reductase"@nl
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|
skos:altLabel
|
"3-hydroxy-3-methylglutaryl-CoA reductase"@en
|
|
"3-hydroxy-3-methylglutaryl-coenzyme A reductase"@en
|
|
"HMG-CoA reductase"@en
|
|
"Hmgcr"@en
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|
"uniprot:Q01237"@en
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|
schema:description
|
"mammalian protein found in Mus musculus"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in 3-hydroxy-3-methylglutaryl-Coenzyme A reductase"@nl
"protèin"@ace
"protéine"@fr
"білок ссавців, наявний у миші хатньої"@uk
"بروتين في فأر المنازل"@ar
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|
schema:dateModified
|
"2023-12-03T14:50:39+00:00"^^xsd:dateTime
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|
schema:version
|
2023060609
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|
wikibase:identifiers
|
13
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|
wikibase:sitelinks
|
0
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|
wikibase:statements
|
71
|
|
p:P129
|
wd:statement/Q14864142-BEEF4AC4-2522-482C-8F39-1759D517342D
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|
p:P31
|
wd:statement/Q14864142-BCB7F435-62B9-4ADA-8737-BA501D15CD77
|
|
p:P352
|
wd:statement/q14864142-8A3924CC-F784-4377-AF29-D946FFD8CA72
|
|
p:P361
|
wd:statement/Q14864142-093ED9B6-6F28-48FB-8023-3C8E5A71A104
|
|
wd:statement/Q14864142-5F3967AB-CF9A-4FCC-AE08-E06369647ED2
|
|
wd:statement/Q14864142-67C27BC1-7DAA-46E7-9AB4-26DFEF489DC2
|
|
wd:statement/Q14864142-7A739AEF-2F0F-4A53-8AC8-B00572699BBC
|
|
wd:statement/Q14864142-99A56549-5E68-4AD8-92ED-5473EF491217
|
|
wd:statement/Q14864142-A83080F5-B38F-4B68-986E-D9FBAF644498
|
|
wd:statement/Q14864142-B9A17644-A88B-42DF-8C27-BEA8DDD6E52A
|
|
wd:statement/Q14864142-C921EF1A-3631-44D3-BD69-5B47E9B74D2D
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|
p:P527
|
wd:statement/Q14864142-94D3C9EC-A24E-4358-B765-2647E4D02D02
|
|
wd:statement/Q14864142-ADEB31EE-378F-4101-B6D1-0F817BD515CE
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|
p:P637
|
wd:statement/Q14864142-09903BDF-9E39-4693-AE37-721F6245B124
|
|
wd:statement/Q14864142-3BF00E30-6531-435C-B08E-AEE054F7449C
|
|
wd:statement/Q14864142-5A101412-26BF-426E-9B07-8A9E2F4766EE
|
|
wd:statement/Q14864142-D8B2A58B-178C-4A74-ABEF-FD9CC503E93E
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|
p:P680
|
wd:statement/Q14864142-1FBE954F-E3A4-477F-B45D-599898233246
|
|
wd:statement/Q14864142-4202CABC-DBF6-45C0-9F4B-412BEDE410D5
|
|
wd:statement/Q14864142-4AF6571D-3FCE-45FE-9F1B-04EC42AF3691
|
|
wd:statement/Q14864142-4F6AD943-D844-4DBE-9802-913E0F4369CF
|
|
wd:statement/Q14864142-7229DC5D-7079-4A77-AEA5-AF6CDC45486B
|
|
wd:statement/Q14864142-802A8965-99F1-4E8D-82F0-36E956BFC0FB
|
|
wd:statement/Q14864142-B0E0A109-E396-4A0B-9892-D57F4F8CBBE1
|
|
wd:statement/Q14864142-E29E3B9D-5AD9-4FBA-AD4E-DC940FF65E1D
|
|
p:P681
|
wd:statement/Q14864142-79B30ED9-7DE0-4B11-822D-53B1D722E054
|
|
wd:statement/Q14864142-7AE5AED0-84E0-44DE-BC11-F93A206F84AF
|
|
wd:statement/Q14864142-94960813-94F6-4DD8-8ACC-7BC4F4C9D08B
|
|
wd:statement/Q14864142-ADC25F1A-D60C-46EA-9041-0208ADF4B19F
|
|
wd:statement/Q14864142-C31B7AC9-1F65-4ACB-BC33-98301D0FD52B
|
|
wd:statement/Q14864142-D6DF69E8-D549-4051-8951-BB9F09331761
|
|
p:P682
|
wd:statement/Q14864142-0A943FB8-6A03-424C-870E-54F5B9D9FC2B
|
|
wd:statement/Q14864142-14227B7E-520E-40F1-899C-0E83E11C4930
|
|
wd:statement/Q14864142-190713D6-BE32-47F2-92C0-5C3AFA730AC1
|
|
wd:statement/Q14864142-19477296-868C-4CC3-A707-58FDE450BBBB
|
|
wd:statement/Q14864142-23569486-B6E5-4085-92E1-486EDE5B8F03
|
|
wd:statement/Q14864142-23A4E19F-301E-42A8-AE8E-CF377BC40040
|
|
wd:statement/Q14864142-2E317CFC-C96F-4D60-9D6D-480B74CA4866
|
|
wd:statement/Q14864142-323C7DCA-7D11-4362-92C5-95AB17DEB388
|
|
wd:statement/Q14864142-39188921-8584-42F2-ADDE-199D6A0B02F1
|
|
wd:statement/Q14864142-3C523EF7-F820-4552-AC21-431CEFA4C513
|
|
wd:statement/Q14864142-3C930F5F-F082-4EAC-8881-84FE32C95D14
|
|
wd:statement/Q14864142-5DE832F8-BA1D-43D5-BB7E-B74AE6EBA55C
|
|
wd:statement/Q14864142-63D79823-EC29-4C26-8DDB-C98352BF7229
|
|
wd:statement/Q14864142-673CBFA8-C3C2-4CA3-BA86-129203DD2A53
|
|
wd:statement/Q14864142-6C536E7B-0080-4DD4-8D42-3855A02F2C15
|
|
wd:statement/Q14864142-73D4E862-4E2C-4559-AF29-2B12C5B81292
|
|
wd:statement/Q14864142-7702E153-2858-4004-B696-AF34023337CF
|
|
wd:statement/Q14864142-7E9AE41B-535F-472C-B32D-340C99CAC79D
|
|
wd:statement/Q14864142-7EC0BDC5-6BF1-4A4E-A1EF-42FD5D7D70DD
|
|
wd:statement/Q14864142-88295848-F40F-41EA-97EE-5CACBFDC0E0F
|
|
wd:statement/Q14864142-8CF2488A-4C8D-47EB-A406-B05C7280D878
|
|
wd:statement/Q14864142-9E800B1D-F9E8-4F76-8721-AA19AF1103B6
|
|
wd:statement/Q14864142-ABD792C0-9869-44E9-89A5-DE79C1F91DB8
|
|
wd:statement/Q14864142-B0EE0952-3930-4D1B-A163-B4367C7A0872
|
|
wd:statement/Q14864142-B1B932F4-7361-4B1D-9E17-6F2F04C662CF
|
|
wd:statement/Q14864142-C0363FCB-DE25-40FF-B5B7-313FC61C538E
|
|
wd:statement/Q14864142-C6927CFF-7186-4C6F-B035-F123DFDC0C09
|
|
wd:statement/Q14864142-D2AEA7DF-5D96-4E8E-8EF3-ACF37F94D5C7
|
|
wd:statement/Q14864142-D90D2186-E4BF-4C65-94F1-A1FA6EAF46BB
|
|
wd:statement/Q14864142-FC5DDCE1-12CF-4016-A985-04ECCF2E4399
|
|
p:P702
|
wd:statement/q14864142-BFC732CD-48A2-440A-B607-5B3B5E562465
|
|
p:P703
|
wd:statement/q14864142-B3DA8D82-C4D4-4655-8693-5161D8786FA8
|
|
p:P705
|
wd:statement/Q14864142-127785EC-46CC-4AB5-8E9C-80C90DEE9F98
|
|
wd:statement/Q14864142-5DBC3A91-F62C-439B-858B-A682F894C09C
|
|
wd:statement/Q14864142-68EED154-4097-46C1-9CB0-59F775CD5EC4
|
|
wd:statement/Q14864142-76720E2B-3B7E-401C-8767-9FB9F55B4167
|
|
wd:statement/Q14864142-794F1DEF-BB5E-471F-886B-05BDF441BA33
|
|
wd:statement/Q14864142-8C542454-594B-42F6-930B-5EC973EC64CF
|
|
wd:statement/Q14864142-9177CC4C-FF55-438A-AAFF-0E5E2245EEDD
|
|
wd:statement/Q14864142-F9551E81-F1C2-48F5-B02C-6AD4E63A0904
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/Q01237>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001347094>
|
|
<http://purl.uniprot.org/refseq/NP_001347095>
|
|
<http://purl.uniprot.org/refseq/NP_032281>
|
|
<http://purl.uniprot.org/refseq/XP_036013747>
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|
wdt:P129
|
lovastatin
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"Q01237"
|
|
wdt:P361
|
Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily
|
|
Hydroxymethylglutaryl-CoA reductase, N-terminal
|
|
Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily
|
|
Hydroxymethylglutaryl-CoA reductase, metazoan
|
|
Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily
|
|
membrane protein
|
|
Sterol-sensing domain, protein family
|
|
Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site, protein family
|
|
wdt:P527
|
Sterol-sensing domain
|
|
Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site
|
|
wdt:P637
|
"NP_001347094"
|
|
"NP_001347095"
|
|
"NP_032281"
|
|
"XP_036013747"
|
|
wdt:P680
|
oxidoreductase activity
|
|
NADP binding
|
|
protein homodimerization activity
|
|
protein phosphatase 2A binding
|
|
hydroxymethylglutaryl-CoA reductase (NADPH) activity
|
|
NADPH binding
|
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oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
|
wdt:P681
|
integral component of membrane
|
|
endoplasmic reticulum membrane
|
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membrane
|
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intracellular membrane-bounded organelle
|
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peroxisomal membrane
|
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endoplasmic reticulum
|
|
wdt:P682
|
steroid metabolic process
|
|
steroid biosynthetic process
|
|
cholesterol biosynthetic process
|
|
negative regulation of apoptotic process
|
|
cholesterol metabolic process
|
|
sterol biosynthetic process
|
|
positive regulation of cell population proliferation
|
|
negative regulation of protein catabolic process
|
|
negative regulation of protein secretion
|
|
protein tetramerization
|
|
positive regulation of cardiac muscle cell apoptotic process
|
|
response to ethanol
|
|
positive regulation of ERK1 and ERK2 cascade
|
|
myoblast differentiation
|
|
positive regulation of skeletal muscle tissue development
|
|
response to nutrient
|
|
positive regulation of smooth muscle cell proliferation
|
|
negative regulation of MAP kinase activity
|
|
ubiquinone metabolic process
|
|
isoprenoid biosynthetic process
|
|
negative regulation of striated muscle cell apoptotic process
|
|
coenzyme A metabolic process
|
|
positive regulation of stress-activated MAPK cascade
|
|
negative regulation of wound healing
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
|
negative regulation of amyloid-beta clearance
|
|
lipid metabolism
|
|
ageing
|
|
visual learning
|
|
wdt:P702
|
Hmgcr
|
|
wdt:P703
|
house mouse
|
|
wdt:P705
|
"ENSMUSP00000022176"
|
|
"ENSMUSP00000126087"
|
|
"ENSMUSP00000126959"
|
|
"ENSMUSP00000128294"
|
|
"ENSMUSP00000128642"
|
|
"ENSMUSP00000128939"
|
|
"ENSMUSP00000132155"
|
|
"ENSMUSP00000132749"
|