Interleukin 6

mammalian protein found in Mus musculus
rdfs:label "Interleukin 6"@en
skos:altLabel "B-cell hybridoma growth factor"@en
"Il6"@en
"interleukin HP-1"@en
"interleukin-6"@en
schema:description
"mammalian protein found in Mus musculus"@en
schema:dateModified "2023-12-03T14:53:06+00:00"^^xsd:dateTime
schema:version 2023062314
wikibase:identifiers 8
wikibase:sitelinks 0
wikibase:statements 137
p:P279 wd:statement/q14865240-7A847712-E4C7-4DBD-A2CF-43CCD6E4468A
p:P2888 wd:statement/Q14865240-799C43AC-EE2B-4B97-93B9-BA1E4967E349
wd:statement/Q14865240-7C0DD586-97CA-4B7F-B864-E3C93024EEB0
wd:statement/Q14865240-DA59A0D3-F7ED-4D79-BC47-97218A271C3D
p:P31 wd:statement/Q14865240-080F39DC-7A5D-47BA-B6D4-87E5F9AF7AB2
p:P352 wd:statement/q14865240-9487324A-DC5B-47E6-AF75-ED9E6AC4AB83
p:P361 wd:statement/Q14865240-0A918372-BB74-4231-89E3-60DCC32F6D74
wd:statement/Q14865240-704CA2BD-8FE5-4E30-8CE7-D48BF4D40D9D
wd:statement/Q14865240-9682778B-DF0C-4B09-B515-BA68D61B033B
p:P527 wd:statement/Q14865240-41DDEC42-B432-4E32-B210-9A49DDCEE80B
p:P637 wd:statement/Q14865240-A9FB0EC6-79DC-403F-89F3-E55D1DB91AD6
wd:statement/Q14865240-F83D6AA1-A229-4DB5-97C0-9D7543BC99A8
p:P638 wd:statement/q14865240-95070749-9FDC-40C6-96FD-654D445B3EC6
p:P680 wd:statement/Q14865240-29290847-DA57-40FE-8805-D85625DCFC97
wd:statement/Q14865240-466CD715-20E3-4232-9AF8-CD23342CB956
wd:statement/Q14865240-C1C74373-5200-4147-A97F-963B0C0294FA
wd:statement/Q14865240-CAFE8722-874C-4A34-817F-672381BACFE7
wd:statement/Q14865240-E5160067-A796-439F-8052-06889CD8E430
p:P681 wd:statement/Q14865240-02E466F4-25E8-4E91-B9CE-59A46D0F75B9
wd:statement/Q14865240-213AE537-8A54-4FFC-939A-139B9AA8EBFC
wd:statement/Q14865240-3AF46209-520B-4498-9F00-4D719C54FC27
wd:statement/Q14865240-8123D7F1-DB1F-48D1-B0CA-EC79077C34AE
wd:statement/Q14865240-DB3D3CAD-0C1B-4BBA-B101-5D88A3A87287
p:P682 wd:statement/Q14865240-0158CC95-CC5A-423E-801C-41E601135B3D
wd:statement/Q14865240-02C5C7FA-1B5C-466A-B4F1-DF8A89172B83
wd:statement/Q14865240-04DD31E6-BFF1-4D55-B4B4-A89D8928A89C
wd:statement/Q14865240-05BDEFCF-9F88-47DE-B77D-2311C517A8F4
wd:statement/Q14865240-06627C5A-79EE-404E-9DFB-41A216FB2F1E
wd:statement/Q14865240-06C8AB5B-D28B-4923-85CF-75CFEE7FF351
wd:statement/Q14865240-06E085BA-4EDB-4313-914C-E3DB53A1455C
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wd:statement/Q14865240-5130C5D9-62C2-4EDC-9BF1-36FAE4A12D83
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wd:statement/Q14865240-5EC06602-634C-4F12-AD90-8D9DBA995C70
wd:statement/Q14865240-615686CB-BF18-469C-829E-C6320F00ED5E
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wd:statement/Q14865240-863CAE16-F44C-40BF-80FD-E162686D5BD2
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wd:statement/Q14865240-99D41E4C-E900-4FE1-886D-61B2A0087A48
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wd:statement/Q14865240-AB1C7974-38DA-4CF6-9168-83E14A36E272
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wd:statement/Q14865240-B6090466-27F9-437C-8B3B-B0D4E32B0CB7
wd:statement/Q14865240-BA2069A9-DD70-4BF9-820D-E541CE29383A
wd:statement/Q14865240-BA51B986-9A9D-4141-91A8-04CC2D6CAB47
wd:statement/Q14865240-BB67409F-F53C-4E4F-B923-F68E1EF79BAA
wd:statement/Q14865240-BD1F832A-2BAE-49EE-A461-348B04336A5D
wd:statement/Q14865240-BD82FECD-0274-445F-A683-71D0BCA11241
wd:statement/Q14865240-C23F7B61-A7E4-44CA-928A-D564F5A130D7
wd:statement/Q14865240-C3799584-06DB-4A52-A291-0882A37E3B97
wd:statement/Q14865240-C38481BE-23E1-43E4-A127-322B4076F6BC
wd:statement/Q14865240-C418EFB2-230E-499A-B06B-F06CBD98B73D
wd:statement/Q14865240-C7FEBE69-CCC6-4249-9977-33EA62190598
wd:statement/Q14865240-C8F5CF63-C24B-4D7D-AAED-A8B5162C0630
wd:statement/Q14865240-CD1F94D1-CEE1-4D6D-8EA1-7FBAB11D4856
wd:statement/Q14865240-CEE73C94-57F1-488B-8DF5-2B2449573E1F
wd:statement/Q14865240-D2FBC86A-1D4B-4B42-AF63-96AC7210275C
wd:statement/Q14865240-D4B402DB-A768-4DC8-ABE3-526C4774A01B
wd:statement/Q14865240-D81B0945-D5E8-4691-BEB8-6B4335890CD0
wd:statement/Q14865240-D971D9E1-158C-4A6B-95D0-DC3559AD54B6
wd:statement/Q14865240-DA5B7349-07A6-46EC-9056-92ED152DB047
wd:statement/Q14865240-DD7A9F3D-F482-4CB3-A1E0-266594D8D335
wd:statement/Q14865240-E3E23434-9594-4589-B3DE-F64F64DC621B
wd:statement/Q14865240-ED20B3E2-6EB6-4347-9532-84889812CD65
wd:statement/Q14865240-F16604E7-49E1-4611-AE81-294AECC917E6
wd:statement/Q14865240-F70B8B10-EE48-4FC2-B65A-4366F5A02B6D
wd:statement/Q14865240-F94B4999-3526-4D64-BDCF-3E031BD976B0
wd:statement/Q14865240-FC73697A-0E0B-47F8-8C99-23D28D6336F1
wd:statement/Q14865240-FD7FD2B7-1013-416D-9C03-293D41C3816C
wd:statement/Q14865240-FF442C57-5588-425B-B204-8A0D1C3E45DB
wd:statement/Q14865240-FF8EE5C4-AEF5-47F9-9F4F-D249858A0525
p:P702 wd:statement/Q14865240-43A05244-1715-4B72-B9F5-BCB304C8F2C4
p:P703 wd:statement/Q14865240-EAE69FBD-2324-4B2D-B69D-BB701913A467
p:P705 wd:statement/Q14865240-35BDF9BB-B13C-46AC-AEAA-A3E28A05E56D
wd:statement/Q14865240-35F96014-CECA-4925-88C3-6CE21FF4E3CC
wd:statement/Q14865240-93E946C2-74CB-4899-8369-99CECC913077
wd:statement/q14865240-21A3CFDC-B47C-4A2B-B5E9-A24E04AA7A4E
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P08505>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_001300983>
<http://purl.uniprot.org/refseq/NP_112445>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/2L3Y>
wdt:P279 protein
wdt:P2888 <http://purl.uniprot.org/uniprot/P08505>
<https://identifiers.org/uniprot:P08505>
<https://www.ncbi.nlm.nih.gov/protein/P08505>
wdt:P31 protein
wdt:P352 "P08505"
wdt:P361 four-helical cytokine-like, core
interleukin-6
Interleukin-6/GCSF/MGF, conserved site, protein family
wdt:P527 Interleukin-6/GCSF/MGF, conserved site
wdt:P637 "NP_001300983"
"NP_112445"
wdt:P638 "2L3Y"
wdt:P680 signaling receptor binding
growth factor activity
cytokine activity
interleukin-6 receptor binding
protein binding
wdt:P681 extracellular space
external side of plasma membrane
extracellular region
interleukin-6 receptor complex
cytoplasm
wdt:P682 response to lipopolysaccharide
positive regulation of neuron projection development
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of cell population proliferation
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to insulin
positive regulation of cell population proliferation
positive regulation of gene expression
regulation of apoptotic process
positive regulation of DNA replication
acute-phase response
endocrine pancreas development
glucose homeostasis
positive regulation of MAPK cascade
positive regulation of nitric oxide biosynthetic process
negative regulation of gluconeogenesis
positive regulation of protein kinase B signaling
positive regulation of apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
response to antibiotic
regulation of cell population proliferation
regulation of cell shape
response to wounding
cellular response to interleukin-1
inflammatory response
cellular response to dexamethasone stimulus
positive regulation of epithelial cell proliferation
positive regulation of receptor signaling pathway via JAK-STAT
positive regulation of peptidyl-serine phosphorylation
response to glucocorticoid
response to electrical stimulus
response to organic cyclic compound
positive regulation of ERK1 and ERK2 cascade
positive regulation of neuron differentiation
response to cold
branching involved in salivary gland morphogenesis
epithelial cell proliferation involved in salivary gland morphogenesis
response to heat
negative regulation of bone resorption
response to cytokine
response to amino acid
cytokine-mediated signaling pathway
cellular response to lipopolysaccharide
cellular response to cytokine stimulus
negative regulation of neuron death
defense response to virus
positive regulation of osteoblast differentiation
positive regulation of smooth muscle cell proliferation
T cell activation
negative regulation of hormone secretion
positive regulation of translation
muscle cell cellular homeostasis
neuron projection development
positive regulation of DNA-binding transcription factor activity
cellular response to estradiol stimulus
positive regulation of T cell proliferation
positive regulation of interleukin-6 production
response to mechanical stimulus
cell redox homeostasis
response to nutrient levels
response to yeast
positive regulation of glial cell proliferation
neutrophil apoptotic process
hepatic immune response
positive regulation of acute inflammatory response
negative regulation of protein kinase activity
regulation of vascular endothelial growth factor production
response to caffeine
positive regulation of chemokine production
negative regulation of collagen biosynthetic process
defense response to protozoan
positive regulation of T-helper 2 cell differentiation
negative regulation of muscle organ development
positive regulation of B cell activation
response to calcium ion
positive regulation of transmission of nerve impulse
glucagon secretion
interleukin-6-mediated signaling pathway
cellular response to hydrogen peroxide
regulation of signaling receptor activity
myeloid cell homeostasis
acute inflammatory response
positive regulation of vascular endothelial growth factor production
cellular response to tumor necrosis factor
cellular response to nutrient levels
positive regulation of epithelial to mesenchymal transition
response to bacterium
response to auditory stimulus
cellular response to hepatocyte growth factor stimulus
positive regulation of tyrosine phosphorylation of STAT protein
negative regulation of interleukin-1-mediated signaling pathway
negative regulation of membrane potential
wound healing
immune response
T-helper 17 cell lineage commitment
regulation of circadian sleep/wake cycle, non-REM sleep
positive regulation of extracellular matrix disassembly
positive regulation of apoptotic DNA fragmentation
positive regulation of T-helper 2 cell cytokine production
positive regulation of gliogenesis
positive regulation of cell proliferation in bone marrow
cellular response to prolactin
lymphocyte costimulation
ageing
bone remodeling
wdt:P702 Il6
wdt:P703 house mouse
wdt:P705 "ENSMUSP00000026845"
"ENSMUSP00000143157"
"ENSMUSP00000143293"
"ENSMUSP00000143544"
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