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rdfs:label
|
"Bruton agammaglobulinemia tyrosine kinase"@en
"Bruton agammaglobulinemia tyrosine kinase"@nl
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skos:altLabel
|
"ATK"@en
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|
"B-cell progenitor kinase"@en
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"BPK"@en
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"Bruton's tyrosine kinase"@en
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"Btk"@en
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|
"Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB)"@en
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|
"X-linked immune deficiency"@en
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|
"agammaglobulinaemia tyrosine kinase"@en
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|
"agammaglobulinemia tyrosine kinase"@en
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|
"bruton tyrosine kinase"@en
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"kinase EMB"@en
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|
"tyrosine-protein kinase BTK"@en
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schema:description
|
"mammalian protein found in Mus musculus"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in Bruton agammaglobulinemia tyrosine kinase"@nl
"protèin"@ace
"protéine"@fr
"білок ссавців, наявний у миші хатньої"@uk
"بروتين في فأر المنازل"@ar
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|
schema:dateModified
|
"2023-12-03T15:05:08+00:00"^^xsd:dateTime
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schema:version
|
2023070342
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wikibase:identifiers
|
8
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wikibase:sitelinks
|
0
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wikibase:statements
|
89
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|
p:P31
|
wd:statement/Q14906044-767EE108-1121-4DC3-8ADF-D7AD7058FE9A
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|
p:P352
|
wd:statement/Q14906044-AD01771D-5793-4A94-B85F-272505FA8336
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|
p:P361
|
wd:statement/Q14906044-28746385-6E6C-4CDA-87D1-C30C149D6F10
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|
wd:statement/Q14906044-30793538-93B5-4416-8F2C-E8AB283CE490
|
|
wd:statement/Q14906044-3174C255-802C-4858-80FA-B123CDE59D9F
|
|
wd:statement/Q14906044-53BCCB1D-3694-42B0-96B6-8CB2DD03DFF7
|
|
wd:statement/Q14906044-66AEF819-3132-4D0B-9F7B-6FC55A87C5B8
|
|
wd:statement/Q14906044-6A05A82A-876B-438C-BC37-FE4E05C34291
|
|
wd:statement/Q14906044-706A7C6F-1BA1-44A4-BB6A-352C982A4ED7
|
|
wd:statement/Q14906044-726162C5-7AA9-44AF-9034-E1DCC7D21FEC
|
|
wd:statement/Q14906044-875544F3-AAB6-4A97-98B8-FAD2B56C476B
|
|
wd:statement/Q14906044-8D533A2F-CB79-47BB-8ABD-FB89DF67CCA2
|
|
wd:statement/Q14906044-95FC1FEC-40D3-4B08-9E12-653C937576C0
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|
wd:statement/Q14906044-97358AFB-6E8E-4F0C-B4B0-BE60F3D5D7F1
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|
wd:statement/Q14906044-B376767A-200C-4119-BD6E-EB1652249C4A
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|
wd:statement/Q14906044-C689944B-FA9D-4D4A-A84E-3D1402FD5301
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|
wd:statement/Q14906044-F72F6CB4-095A-4F18-AA7E-AB881735FAFA
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|
p:P527
|
wd:statement/Q14906044-01D04469-C676-4878-B157-232A2D0B8C9E
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|
wd:statement/Q14906044-1155C5BC-8994-4D4D-964D-2E07AC2119F1
|
|
wd:statement/Q14906044-234D1D78-6590-40A6-BAAD-E3C313FA3BE7
|
|
wd:statement/Q14906044-6EA2F1E7-F6E7-411D-85A1-9920A245E3EC
|
|
wd:statement/Q14906044-7F0EB11F-D51C-4F25-9E27-90AD31931D26
|
|
wd:statement/Q14906044-94CC6D51-AC6D-4CB9-BDA4-01C2049102D6
|
|
wd:statement/Q14906044-9C5D6632-4865-4425-AEAF-0CFBC3A6F99E
|
|
wd:statement/Q14906044-9C7FF50A-B8E8-412B-83E9-B8D01943BACE
|
|
wd:statement/Q14906044-E08F94B4-E700-432E-B3DC-F1D14AC9C830
|
|
wd:statement/Q14906044-F9A1F89A-B9A1-455E-8AE7-F8CDE03626C1
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|
p:P637
|
wd:statement/Q14906044-23C8821F-8A04-4845-A28D-42F71CFC8B16
|
|
wd:statement/Q14906044-7A55991E-8E95-4998-8E36-7E23EB782DD3
|
|
wd:statement/Q14906044-D302CA7F-F710-4A9B-AAEB-6F1D9DF31F00
|
|
wd:statement/Q14906044-F69F3ED0-A3CB-4E41-B37C-A91AAC4E2812
|
|
p:P638
|
wd:statement/Q14906044-8E8E4AF2-3C97-41FA-85BF-43661CD34C06
|
|
p:P680
|
wd:statement/Q14906044-0B7B9321-AEF4-4A04-9D1C-0FC618B27CE3
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|
wd:statement/Q14906044-0BB32E1A-26EA-4AA7-B30D-703CBB6D1BA2
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|
wd:statement/Q14906044-37D3DE4E-41E5-4401-B6DC-A5574D3112D5
|
|
wd:statement/Q14906044-59C62FC4-F101-4F10-8251-28BF2AFD92AC
|
|
wd:statement/Q14906044-6C59BB46-FF28-4CA5-A0D3-80B51624266C
|
|
wd:statement/Q14906044-7C04BD5B-6071-476F-8EEF-59D57D49DA18
|
|
wd:statement/Q14906044-7F5B1B53-A787-4D87-9FE8-E151A7482EA3
|
|
wd:statement/Q14906044-82801223-CA8A-49F7-9A6E-AEA69047F1FA
|
|
wd:statement/Q14906044-88FC62A6-74D4-4802-91CD-A4AD126F75B1
|
|
wd:statement/Q14906044-9704A4FB-EEA8-4212-A1EB-8335496BF9D7
|
|
wd:statement/Q14906044-CD4F2A9E-8E4A-4348-BD2C-E67848DEB059
|
|
wd:statement/Q14906044-DE2E6A76-6E64-45D7-AABA-DB3109AC2EA8
|
|
wd:statement/Q14906044-E80ACF02-4290-480C-85C4-F71E07635ECE
|
|
wd:statement/Q14906044-F81639CD-C298-4983-AB11-47F023A800D2
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|
p:P681
|
wd:statement/Q14906044-0DB72EB7-DE58-4C1C-BB45-A15F84C3EF7D
|
|
wd:statement/Q14906044-0EBD6BC9-B00E-40FA-A47B-A6F5E078B610
|
|
wd:statement/Q14906044-285E562C-047B-4491-A7C8-E26699842BF9
|
|
wd:statement/Q14906044-3EB6DC2B-8693-47D8-88FA-CB995ED98001
|
|
wd:statement/Q14906044-4AB0E685-194E-412D-943D-FC8C716CDA20
|
|
wd:statement/Q14906044-4B1A1030-BEE4-4837-9F34-4102E1C8D605
|
|
wd:statement/Q14906044-8F3E15E3-01C5-4627-A91C-DE1D1C8FC66A
|
|
wd:statement/Q14906044-9881153F-F95D-4A75-A0E9-53DFEA61242E
|
|
wd:statement/Q14906044-C179CEDD-F2E1-43E8-964B-A625EF03C875
|
|
wd:statement/Q14906044-DCCF9442-BEF6-44B8-B18D-2A5A1F61F7EE
|
|
p:P682
|
wd:statement/Q14906044-0B00D574-AD0B-4312-A148-0B7CD9D8056E
|
|
wd:statement/Q14906044-1ABDA48D-C24C-4C3E-BA6A-92BC8DA3F02C
|
|
wd:statement/Q14906044-1C87DA08-D8FA-4866-A182-629D38A6F7F9
|
|
wd:statement/Q14906044-1F629C20-AF49-4643-8D24-96BAE94E8A30
|
|
wd:statement/Q14906044-298CE445-A7D1-4D6D-A930-AA7B9B75EF25
|
|
wd:statement/Q14906044-2BAE37A2-3EF7-4BA7-9B3C-F47240B9CCD9
|
|
wd:statement/Q14906044-2EC5FE72-0173-4D6A-83B9-EB8FEF17BF5C
|
|
wd:statement/Q14906044-3EC16FC7-2F64-4C0A-8C33-FF1A2BEF4EDB
|
|
wd:statement/Q14906044-4EF57C8E-2DE6-49F6-B4A9-2B2534B2BFC3
|
|
wd:statement/Q14906044-525E38DA-6CDE-44F0-96C4-C830AA821382
|
|
wd:statement/Q14906044-5506AE65-51B0-45C1-B620-F254C84A60C1
|
|
wd:statement/Q14906044-57063368-3999-4AAF-B55A-FF81BD335DF9
|
|
wd:statement/Q14906044-5FB9E5B4-F86A-4B1E-B465-0FDF62ADBB51
|
|
wd:statement/Q14906044-6F0550EA-DD0A-4D9F-872B-8B62F3AFA777
|
|
wd:statement/Q14906044-7530D81D-9506-47AC-969F-25778A9CDFAA
|
|
wd:statement/Q14906044-775DA645-61C3-4CCB-A366-D6B6F1F4836D
|
|
wd:statement/Q14906044-7F35D4E1-7447-447D-8459-FB32EA20155B
|
|
wd:statement/Q14906044-8E80620D-CFDD-4230-A810-7F61BF402673
|
|
wd:statement/Q14906044-8F29E62F-3CE1-4381-852D-7CDA28340E12
|
|
wd:statement/Q14906044-A6BECC46-C5F0-4A69-9243-D21369BDEA1A
|
|
wd:statement/Q14906044-ABB9B6D7-7C7E-498B-ABD1-A96187B516AA
|
|
wd:statement/Q14906044-B2855F71-1A7B-4DDF-8B81-A2F78B6B5D46
|
|
wd:statement/Q14906044-BD539EEA-A218-41F1-9AB3-3643778BBCC6
|
|
wd:statement/Q14906044-C180F9C5-F7AF-4902-BC4E-214F48CD3A34
|
|
wd:statement/Q14906044-C75E2F27-8F6F-47CE-8489-AA667D92D855
|
|
wd:statement/Q14906044-D517B529-D6B3-47B3-A2BB-E7AB86D16486
|
|
wd:statement/Q14906044-D5828022-FBEF-4E01-A82A-653EC9EE6932
|
|
wd:statement/Q14906044-D6910B97-39D3-43A1-8182-5750F41997A8
|
|
wd:statement/Q14906044-FD44248D-0D60-4B49-B7C4-F974178ED36D
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|
p:P702
|
wd:statement/Q14906044-53792E1C-C06D-45D8-832F-A5E6F97968B9
|
|
p:P703
|
wd:statement/Q14906044-1C7502CA-EFF8-42BA-AD1D-D077852C5646
|
|
p:P705
|
wd:statement/Q14906044-88222B9F-0A43-42D9-987A-E9EEC1B32AB5
|
|
wd:statement/Q14906044-D5CC0E32-B3DE-4D73-8F96-9312DF36D835
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P35991>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_038510>
|
|
<http://purl.uniprot.org/refseq/XP_006528546>
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|
<http://purl.uniprot.org/refseq/XP_006528547>
|
|
<http://purl.uniprot.org/refseq/XP_006528548>
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p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/4XI2>
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wdt:P31
|
protein
|
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wdt:P352
|
"P35991"
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|
wdt:P361
|
Protein kinase-like domain superfamily
|
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PH-like domain superfamily
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|
SH3-like domain superfamily
|
|
SH2 domain superfamily
|
|
membrane protein
|
|
Tyrosine-protein kinase, catalytic domain, protein family
|
|
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
|
|
Protein kinase domain, protein family
|
|
SH3 domain, protein family
|
|
pleckstrin homology domain, protein family
|
|
SH2 domain, protein family
|
|
Tyrosine-protein kinase BTK, SH3 domain, protein family
|
|
Tyrosine-protein kinase, active site, protein family
|
|
Zinc finger, Btk motif, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P527
|
tyrosine-protein kinase, catalytic domain
|
|
Zinc finger, Btk motif
|
|
tyrosine-protein kinase, active site
|
|
serine-threonine/tyrosine-protein kinase, catalytic domain
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
SH3 domain
|
|
pleckstrin homology domain
|
|
SH2 domain
|
|
Tyrosine-protein kinase BTK, SH3 domain
|
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wdt:P637
|
"NP_038510"
|
|
"XP_006528546"
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|
"XP_006528547"
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"XP_006528548"
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wdt:P638
|
"4XI2"
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wdt:P680
|
metal ion binding
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lipid binding
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identical protein binding
|
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ATP binding
|
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signaling receptor binding
|
|
protein kinase activity
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|
transferase activity
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nucleotide binding
|
|
kinase activity
|
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protein tyrosine kinase activity
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non-membrane spanning protein tyrosine kinase activity
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phosphatidylinositol-3,4,5-trisphosphate binding
|
|
protein binding
|
|
wdt:P681
|
perinuclear region of cytoplasm
|
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membrane
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cytoplasmic vesicle
|
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mast cell granule
|
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extrinsic component of cytoplasmic side of plasma membrane
|
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cytosol
|
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plasma membrane
|
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nucleus
|
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membrane raft
|
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cytoplasm
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wdt:P682
|
peptidyl-tyrosine phosphorylation
|
|
apoptotic process
|
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regulation of transcription, DNA-templated
|
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transcription, DNA-templated
|
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intracellular signal transduction
|
|
cell maturation
|
|
response to organic substance
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
|
B cell receptor signaling pathway
|
|
T cell receptor signaling pathway
|
|
negative regulation of B cell proliferation
|
|
negative regulation of cytokine production
|
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adaptive immune response
|
|
histamine secretion by mast cell
|
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cellular response to reactive oxygen species
|
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cellular response to molecule of fungal origin
|
|
immune system process
|
|
peptidyl-tyrosine autophosphorylation
|
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I-kappaB kinase/NF-kappaB signaling
|
|
positive regulation of type I hypersensitivity
|
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positive regulation of type III hypersensitivity
|
|
B cell affinity maturation
|
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cellular response to interleukin-7
|
|
phosphorylation
|
|
protein autophosphorylation
|
|
innate immune response
|
|
protein phosphorylation
|
|
wdt:P702
|
Btk
|
|
wdt:P703
|
house mouse
|
|
wdt:P705
|
"ENSMUSP00000033617"
|
|
"ENSMUSP00000108839"
|