Integrin beta 3

mammalian protein found in Mus musculus
rdfs:label
"Integrin beta 3"@en
skos:altLabel "GPIIIa"@en
"Itgb3"@en
"integrin beta-3"@en
"platelet glycoprotein IIIa (GP3A)"@en
"platelet gpIIIa"@en
"platelet membrane glycoprotein IIIa"@en
schema:description
"mammalian protein found in Mus musculus"@en
schema:dateModified "2023-12-03T15:14:57+00:00"^^xsd:dateTime
schema:version 2023076343
wikibase:identifiers 4
wikibase:sitelinks 0
wikibase:statements 141
p:P31 wd:statement/Q14913644-07C08E30-682C-4F6A-B0EA-6DF85F571EC8
p:P352 wd:statement/Q14913644-B8A10CFA-27B0-41AF-8610-6123F2BBBCAA
p:P361 wd:statement/Q14913644-03892ECE-1D22-4495-8532-2A96ADECD8C6
wd:statement/Q14913644-056B0D88-7B6F-4F1A-9E92-8B80E3C13080
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wd:statement/Q14913644-8FBE1E31-C3C1-4520-83C5-AB7835F4495D
p:P527 wd:statement/Q14913644-1801FF8D-6DD0-4D5B-B26A-AB733370D0DA
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wd:statement/Q14913644-DEE45EE3-5682-4CDC-A0B8-532E73F8C737
p:P637 wd:statement/Q14913644-28316905-B497-4749-8C84-4171DBB57EFC
wd:statement/Q14913644-F54918FC-5A76-4C4E-ABD2-0487433FF37F
p:P680 wd:statement/Q14913644-037C3CA8-72E5-4946-995B-3F6719ED87FB
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wd:statement/Q14913644-FFFE08A7-096B-45F5-AC96-DEAB7D7694B2
p:P682 wd:statement/Q14913644-03DDB9AE-D865-4C66-A081-2891067552EA
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wd:statement/Q14913644-A3E3DC82-B49C-4A92-80F0-C4E4DE9396D0
wd:statement/Q14913644-A4B56051-FF49-4DE1-BF49-D25EBAA82A93
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wd:statement/Q14913644-BC1F4DD4-DFC9-4FCF-B811-B03DBE69A816
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wd:statement/Q14913644-C024DE9A-87D3-4D66-9B38-AF652B9280E3
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wd:statement/Q14913644-CACF4832-04EB-4D5E-8FB8-3AE73B2A03A7
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wd:statement/Q14913644-D1220FAB-4749-4A0D-BC46-3EF4B0311429
wd:statement/Q14913644-D1527E6B-D262-43D8-B8CD-3C1957C4D118
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wd:statement/Q14913644-EA1F24E2-3B1B-4AEC-AB1C-1407F6FFF6A5
wd:statement/Q14913644-F4695EF8-7542-4CC2-B007-9507D570935A
wd:statement/Q14913644-F50067A8-9A09-4661-9C6F-1287BEFB4B90
wd:statement/Q14913644-FB11EFE0-8E1F-40E7-BF25-29D4F722DB5F
wd:statement/Q14913644-FBCC0953-0B86-409A-97D5-B95C4A60CB55
wd:statement/Q14913644-FC4C195C-1D66-4156-A21E-3EBA2A397585
wd:statement/Q14913644-FCB58191-5EB3-46B6-AC4D-D7124DDC5EC4
wd:statement/Q14913644-FD961DD1-05B1-4AED-843B-E556200F43EF
p:P702 wd:statement/Q14913644-1D813D1E-5E95-4393-925F-A519445359BF
p:P703 wd:statement/Q14913644-BFA05AC7-6075-4E96-B57A-954934576574
p:P705 wd:statement/Q14913644-EEB507AD-E774-4EF8-8186-FE9F450E0043
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/O54890>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_058060>
<http://purl.uniprot.org/refseq/XP_006532375>
wdt:P31 protein
wdt:P352 "O54890"
wdt:P361 integrin beta-3 subunit
Integrin domain superfamily
Integrin beta tail domain superfamily
von Willebrand factor A-like domain superfamily
membrane protein
EGF-like domain, extracellular domain, protein family
Integrin beta subunit, cytoplasmic domain, protein family
PSI domain, protein family
Integrin beta subunit, VWA domain, protein family
Integrin beta subunit, tail, protein family
Integrin beta N-terminal domain, protein family
wdt:P527 EGF-like domain, extracellular
Integrin beta subunit, cytoplasmic domain
PSI domain
Integrin beta subunit, VWA domain
Integrin beta subunit, tail
Integrin beta N-terminal
wdt:P637 "NP_058060"
"XP_006532375"
wdt:P680 enzyme binding
integrin binding
peptide binding
protease binding
identical protein binding
insulin-like growth factor I binding
extracellular matrix binding
fibroblast growth factor binding
protein kinase C binding
cell adhesion molecule binding
fibronectin binding
fibrinogen binding
protein disulfide isomerase activity
vascular endothelial growth factor receptor 2 binding
protein binding
C-X3-C chemokine binding
neuregulin binding
wdt:P681 melanosome
integral component of membrane
membrane
cell projection
external side of plasma membrane
apical plasma membrane
filopodium membrane
receptor complex
ruffle membrane
lamellipodium membrane
microvillus membrane
integrin complex
integrin alpha9-beta1 complex
alpha9-beta1 integrin-ADAM8 complex
synapse
cell junction
cell surface
integrin alphav-beta3 complex
alphav-beta3 integrin-IGF-1-IGF1R complex
alphav-beta3 integrin-HMGB1 complex
alphav-beta3 integrin-PKCalpha complex
glutamatergic synapse
plasma membrane
integral component of synaptic membrane
nucleus
focal adhesion
wdt:P682 positive regulation of peptidyl-tyrosine phosphorylation
cellular calcium ion homeostasis
positive regulation of gene expression
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of cell migration
regulation of protein localization
positive regulation of MAPK cascade
positive regulation of leukocyte migration
cell-substrate junction assembly
platelet activation
substrate adhesion-dependent cell spreading
cell-matrix adhesion
negative regulation of cell death
response to activity
positive regulation of ERK1 and ERK2 cascade
embryo implantation
positive regulation of endothelial cell migration
positive regulation of fibroblast proliferation
cellular response to mechanical stimulus
negative regulation of macrophage derived foam cell differentiation
negative regulation of lipid storage
activation of protein kinase activity
positive regulation of bone resorption
regulation of cell migration
smooth muscle cell migration
platelet-derived growth factor receptor signaling pathway
response to radiation
positive regulation of smooth muscle cell migration
cell-substrate adhesion
positive regulation of smooth muscle cell proliferation
positive regulation of cell-matrix adhesion
apoptotic cell clearance
positive regulation of endothelial cell proliferation
positive regulation of angiogenesis
integrin-mediated signaling pathway
regulation of actin cytoskeleton organization
cell adhesion mediated by integrin
positive regulation of osteoblast proliferation
positive regulation of osteoclast differentiation
positive regulation of fibroblast migration
heterotypic cell-cell adhesion
positive regulation of cell adhesion mediated by integrin
cell projection morphogenesis
regulation of G protein-coupled receptor signaling pathway
negative chemotaxis
negative regulation of lipid transport
negative regulation of lipoprotein metabolic process
platelet aggregation
regulation of release of sequestered calcium ion into cytosol
cell adhesion
cell migration
positive regulation of T cell migration
apolipoprotein A-I-mediated signaling pathway
cellular response to platelet-derived growth factor stimulus
response to platelet-derived growth factor
regulation of extracellular matrix organization
regulation of protein tyrosine kinase activity
cellular response to insulin-like growth factor stimulus
positive regulation of glomerular mesangial cell proliferation
regulation of serotonin uptake
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway
regulation of postsynaptic neurotransmitter receptor internalization
viral entry into host cell
wdt:P702 Itgb3
wdt:P703 house mouse
wdt:P705 "ENSMUSP00000021028"
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