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rdfs:label
|
"Janus kinase 2"@en
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|
skos:altLabel
|
"JAK-2"@en
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|
"Jak2"@en
|
|
"tyrosine-protein kinase JAK2"@en
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|
schema:description
|
"mammalian protein found in Mus musculus"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in Janus kinase 2"@nl
"protèin"@ace
"protéine"@fr
"білок ссавців, наявний у миші хатньої"@uk
"بروتين في فأر المنازل"@ar
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schema:dateModified
|
"2023-12-03T15:17:46+00:00"^^xsd:dateTime
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schema:version
|
2023078202
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wikibase:identifiers
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12
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wikibase:sitelinks
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0
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p:direct-normalized/P352
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<http://purl.uniprot.org/uniprot/Q62120>
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p:direct-normalized/P637
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<http://purl.uniprot.org/refseq/NP_001041642>
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<http://purl.uniprot.org/refseq/NP_032439>
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<http://purl.uniprot.org/refseq/XP_006526776>
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<http://purl.uniprot.org/refseq/XP_006526777>
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<http://purl.uniprot.org/refseq/XP_006526778>
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<http://purl.uniprot.org/refseq/XP_011245457>
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<http://purl.uniprot.org/refseq/XP_017173557>
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p:direct-normalized/P638
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<https://rdf.wwpdb.org/pdb/2HDX>
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<https://rdf.wwpdb.org/pdb/4GL9>
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wdt:P31
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protein
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wdt:P352
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"Q62120"
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wdt:P361
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Protein kinase-like domain superfamily
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tyrosine-protein kinase, non-receptor Jak2
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FERM superfamily, second domain
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SH2 domain superfamily
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membrane protein
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Tyrosine-protein kinase, catalytic domain, protein family
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FERM domain, protein family
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Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
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Protein kinase domain, protein family
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SH2 domain, protein family
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Band 4.1 domain, protein family
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Tyrosine-protein kinase JAK2, SH2 domain, protein family
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JAK2, FERM domain C-lobe, protein family
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Janus kinase 2, catalytic domain, protein family
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Janus kinase 2, pseudokinase domain, protein family
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Tyrosine-protein kinase, active site, protein family
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Protein kinase, ATP binding site, protein family
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wdt:P527
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tyrosine-protein kinase, catalytic domain
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FERM domain
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tyrosine-protein kinase, active site
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serine-threonine/tyrosine-protein kinase, catalytic domain
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protein kinase domain
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protein kinase, ATP binding site
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SH2 domain
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Band 4.1 domain
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Janus kinase 2, pseudokinase domain
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Janus kinase 2, catalytic domain
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Tyrosine-protein kinase JAK2, SH2 domain
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JAK2, FERM domain C-lobe
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wdt:P637
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"NP_001041642"
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"NP_032439"
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"XP_006526776"
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"XP_006526777"
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"XP_006526778"
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"XP_011245457"
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"XP_017173557"
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wdt:P638
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"2HDX"
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"4GL9"
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wdt:P680
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metal ion binding
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heme binding
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identical protein binding
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ATP binding
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protein kinase binding
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protein C-terminus binding
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signaling receptor binding
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peptide hormone receptor binding
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protein kinase activity
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transferase activity
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type 1 angiotensin receptor binding
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nucleotide binding
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histone binding
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kinase activity
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protein tyrosine kinase activity
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SH2 domain binding
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phosphatidylinositol 3-kinase binding
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insulin receptor substrate binding
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acetylcholine receptor binding
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non-membrane spanning protein tyrosine kinase activity
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growth hormone receptor binding
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interleukin-12 receptor binding
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histone kinase activity (H3-Y41 specific)
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protein binding
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wdt:P681
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caveola
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membrane
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nucleoplasm
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extrinsic component of cytoplasmic side of plasma membrane
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cytoskeleton
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cytosol
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postsynapse
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glutamatergic synapse
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plasma membrane
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nucleus
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membrane raft
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cytoplasm
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endomembrane system
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focal adhesion
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nuclear matrix
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wdt:P682
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response to lipopolysaccharide
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positive regulation of phosphatidylinositol 3-kinase signaling
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peptidyl-tyrosine phosphorylation
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positive regulation of peptidyl-tyrosine phosphorylation
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modulation of chemical synaptic transmission
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response to oxidative stress
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negative regulation of cell population proliferation
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negative regulation of apoptotic process
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response to tumor necrosis factor
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positive regulation of cell population proliferation
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G protein-coupled receptor signaling pathway
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positive regulation of cell migration
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positive regulation of nitric oxide biosynthetic process
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positive regulation of cell differentiation
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positive regulation of apoptotic process
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positive regulation of transcription by RNA polymerase II
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response to antibiotic
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inflammatory response
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negative regulation of cell death
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cellular response to dexamethasone stimulus
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growth hormone receptor signaling pathway via JAK-STAT
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regulation of receptor signaling pathway via JAK-STAT
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negative regulation of neuron apoptotic process
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positive regulation of cytosolic calcium ion concentration
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tyrosine phosphorylation of STAT protein
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intracellular signal transduction
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erythrocyte differentiation
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hormone-mediated signaling pathway
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positive regulation of inflammatory response
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regulation of inflammatory response
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microglial cell activation
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activation of cysteine-type endopeptidase activity involved in apoptotic process
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myeloid cell differentiation
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platelet-derived growth factor receptor signaling pathway
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positive regulation of insulin secretion
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cytokine-mediated signaling pathway
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cellular response to lipopolysaccharide
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axon regeneration
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positive regulation of DNA binding
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positive regulation of growth hormone receptor signaling pathway
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tumor necrosis factor-mediated signaling pathway
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positive regulation of MHC class II biosynthetic process
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positive regulation of DNA-binding transcription factor activity
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negative regulation of heart contraction
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positive regulation of tumor necrosis factor production
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interferon-gamma-mediated signaling pathway
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intrinsic apoptotic signaling pathway in response to oxidative stress
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enzyme linked receptor protein signaling pathway
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positive regulation of cell-substrate adhesion
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positive regulation of apoptotic signaling pathway
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regulation of cell adhesion
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positive regulation of nitric-oxide synthase biosynthetic process
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negative regulation of DNA binding
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response to hydroperoxide
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receptor signaling pathway via JAK-STAT
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adaptive immune response
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negative regulation of cell-cell adhesion
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positive regulation of interleukin-1 beta production
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extrinsic apoptotic signaling pathway
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activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
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growth hormone receptor signaling pathway
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positive regulation of tyrosine phosphorylation of STAT protein
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activation of Janus kinase activity
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positive regulation of cell activation
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negative regulation of cardiac muscle cell apoptotic process
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positive regulation of phosphoprotein phosphatase activity
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mineralocorticoid receptor signaling pathway
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interleukin-12-mediated signaling pathway
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mammary gland epithelium development
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response to interleukin-12
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programmed cell death induced by symbiont
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response to granulocyte macrophage colony-stimulating factor
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immune system process
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post-embryonic hemopoiesis
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chromatin organization
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peptidyl-tyrosine autophosphorylation
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cellular response to interleukin-3
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cell migration
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cell differentiation
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regulation of nitric oxide biosynthetic process
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positive regulation of growth factor dependent skeletal muscle satellite cell proliferation
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positive regulation of epithelial cell apoptotic process
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positive regulation of vascular associated smooth muscle cell proliferation
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postsynapse to nucleus signaling pathway
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phosphorylation
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protein autophosphorylation
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innate immune response
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positive regulation of cold-induced thermogenesis
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protein phosphorylation
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signal transduction
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wdt:P702
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Jak2
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wdt:P703
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house mouse
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wdt:P705
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"ENSMUSP00000025705"
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"ENSMUSP00000064394"
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