CD28 molecule

mammalian protein found in Homo sapiens
rdfs:label
"CD28 molecule"@en
skos:altLabel "CD28"@en
"CD28 Antigens"@en
"CD28 antigen"@en
"T-cell-specific surface glycoprotein CD28"@en
"TP44"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2025-08-08T23:04:59+00:00"^^xsd:dateTime
schema:version 2389521083
wikibase:identifiers 16
wikibase:sitelinks 14
wikibase:statements 76
p:P10283 wd:statement/Q1622348-71D99974-752B-4605-BE9A-306138854155
p:P31 wd:statement/Q1622348-28E16E5B-2511-48A4-871B-9EA0D966B7F2
p:P352 wd:statement/q1622348-4BCB19A3-FDE5-4170-9E58-AEC901F0E7D6
p:P361 wd:statement/Q1622348-7750936D-379E-41BA-BBF6-D722407E7B5F
wd:statement/Q1622348-77E4B41B-3D8A-415C-AF44-64AC32779140
wd:statement/Q1622348-8169E5A7-8908-4E30-86BA-0AA865633F5B
wd:statement/Q1622348-E9E79FD1-31F7-44A4-9C38-716CEB857D18
p:P527 wd:statement/Q1622348-41335742-097E-46A5-A5CF-9E18BBBBB1AE
p:P6366 wd:statement/Q1622348-107AF950-E949-4A89-8726-509BC8F763F4
p:P637 wd:statement/Q1622348-21AA3960-B9FA-48DE-829E-AFD11E288718
wd:statement/Q1622348-5CECAD63-EC8E-41CB-80CA-35294C7B1D0E
wd:statement/Q1622348-788F90DE-488B-4070-B9AB-725C7654BF5B
wd:statement/Q1622348-B0C3F890-DF24-4099-AE25-FF0DC54018E9
wd:statement/Q1622348-CABBED07-2FA1-405D-91C7-98487E5050DE
wd:statement/Q1622348-D48B4036-3182-4F5C-B982-8D365F601F04
p:P638 wd:statement/Q1622348-4550D2C4-885A-4AE6-A5A9-45114C4DA1E9
wd:statement/Q1622348-8C2D75AF-41A5-486B-B87C-6B8B930A6563
wd:statement/Q1622348-BB2BB56A-323C-45E7-8755-7A06324150FF
p:P646 wd:statement/Q1622348-7EFA19FA-5AE2-40EE-93DA-C5FCD1E2A069
p:P680 wd:statement/Q1622348-156AA327-688D-4BAA-B11A-5C0368ECD82F
wd:statement/Q1622348-30202640-24BB-40A5-B437-ED77F0948227
wd:statement/Q1622348-3C5FD840-1FA7-4850-A55E-B80C658EC1C8
wd:statement/Q1622348-3E1B96EC-C4C7-4EAD-8C8A-6ECC5492BF24
wd:statement/Q1622348-8B04703F-411E-4BD8-90B4-39E8A1A625D6
wd:statement/Q1622348-E86DBA57-02CA-459E-AF2E-8A28E811A620
p:P681 wd:statement/Q1622348-109CCF59-0FB0-4BE9-A325-38022AA93842
wd:statement/Q1622348-35A9D9D4-3745-40E2-B0DA-42CA20B96050
wd:statement/Q1622348-5EE84FAF-4DA6-4D6F-990D-AB86F5EF57CB
wd:statement/Q1622348-65103E27-DFD7-4D78-9703-87139ED26850
wd:statement/Q1622348-A993E454-D992-43DA-AE94-3D61F8455ADB
wd:statement/Q1622348-ADEBB1AC-0607-4B5C-9835-1CD52C58A4C4
wd:statement/Q1622348-C030EEEA-F79D-4B70-8D5E-87F588B8C347
wd:statement/Q1622348-C31AE2DE-DCDB-4DE7-9733-73C359327D1F
wd:statement/Q1622348-D6FDDB01-BCC6-4CAF-9022-289D7C4D14CE
wd:statement/Q1622348-E710FB2C-D0F4-4A8E-A139-F96FBC184D8C
p:P682 wd:statement/Q1622348-0104CD22-24B8-425A-8EB3-75E0090A8B53
wd:statement/Q1622348-04627368-AA4E-4702-9A9C-8F9682BCB56D
wd:statement/Q1622348-06F0BA62-215A-4E04-9798-A78E2D3FB038
wd:statement/Q1622348-2D4D5582-51CA-43FD-9D94-48F1A29BA638
wd:statement/Q1622348-3A16B5C4-BE70-49DA-ACE9-54AD6755163B
wd:statement/Q1622348-40E8FCD7-FC6A-48A6-B47E-94FAFA4D4971
wd:statement/Q1622348-423A66CE-A0F2-4695-863C-92E2661C9714
wd:statement/Q1622348-441B00FA-DA7D-4BE2-BD20-AF41021AF112
wd:statement/Q1622348-45101AA0-A225-44BD-A0C6-573651F47AE2
wd:statement/Q1622348-45C828AF-94B6-4220-A0A3-FA990CD6A390
wd:statement/Q1622348-51A46E80-5ECD-4627-A140-2640DD5F2FAE
wd:statement/Q1622348-59031779-F29B-4DD0-B374-4F6837BFB26F
wd:statement/Q1622348-5A4CC7A9-34D6-4FA9-9608-BCF7DFE1C49F
wd:statement/Q1622348-5F635C4F-AC3C-41DC-A6E9-94D0C823F660
wd:statement/Q1622348-64D35B4A-6922-407A-AD87-355EBD3737CA
wd:statement/Q1622348-6F626EDE-F6A3-4698-8DAD-76105413AB45
wd:statement/Q1622348-6F669024-EF5B-4A69-A0A6-BD93A4AB0A3A
wd:statement/Q1622348-709946FD-199B-4F55-9EBB-9FA8C2619D2E
wd:statement/Q1622348-7154E71A-0C7A-47AA-A11D-2A08216DA9B6
wd:statement/Q1622348-740D7942-A94C-433B-8B68-1492EB51FBA7
wd:statement/Q1622348-7E1370C6-122E-442B-8DD0-D6C17B2DD9EF
wd:statement/Q1622348-7F5D896C-B795-4B52-B881-A071AFD1F1F2
wd:statement/Q1622348-8B76FB36-645F-4A63-9DB7-8B77880EDD9B
wd:statement/Q1622348-9E62EF54-BCAA-4A7B-A046-FD7EDBA95178
wd:statement/Q1622348-9EC1E134-5B11-4132-809B-F7949A19CE32
wd:statement/Q1622348-9FEEA5B3-C45A-494D-A77B-003E9E8CF243
wd:statement/Q1622348-AFA1BDF5-E760-4F94-845C-103C76AA15E3
wd:statement/Q1622348-B4FD5412-49ED-4A96-8240-6E0622C0F9E9
wd:statement/Q1622348-B71D91F7-0B6E-4528-9000-6C8DCEB55F13
wd:statement/Q1622348-C80E2943-C438-4FAA-8B14-43444802D6F4
wd:statement/Q1622348-DBD486AF-240D-4952-AFE4-FE52671BC4F5
wd:statement/Q1622348-E8A7549F-65D6-493A-BFE9-0079C7F9F5D9
wd:statement/Q1622348-E8FE67DD-8F80-4C4A-825F-C655F464CD26
wd:statement/Q1622348-F2BDE221-6501-4CBD-B67F-6364EEF24B5B
wd:statement/Q1622348-FE988F7A-4704-4182-8F3A-CC40EA2B9C72
p:P692 wd:statement/Q1622348-3EC46049-0433-4CFB-BFCF-034DE27A527D
p:P702 wd:statement/Q1622348-9548B592-8BEB-4A60-AD81-7CC557FB27DA
p:P703 wd:statement/Q1622348-9F5590A6-F852-41D3-AA41-9F834A20F282
p:P705 wd:statement/Q1622348-0E785178-1B4F-47DA-B40B-5462FB8137CA
wd:statement/Q1622348-5839EFA9-1341-435C-A98F-4D9121195D4B
wd:statement/Q1622348-E24E11B5-290B-4558-95AA-9F702D1DC5DA
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P10747>
p:direct-normalized/P6366 <https://makg.org/entity/148125776>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_001230006>
<http://purl.uniprot.org/refseq/NP_001230007>
<http://purl.uniprot.org/refseq/NP_006130>
<http://purl.uniprot.org/refseq/XP_011510496>
<http://purl.uniprot.org/refseq/XP_011510497>
<http://purl.uniprot.org/refseq/XP_011510499>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1YJD>
<https://rdf.wwpdb.org/pdb/3WA4>
<https://rdf.wwpdb.org/pdb/5AUL>
wdt:P10283 "C148125776"
wdt:P31 protein
wdt:P352 "P10747"
wdt:P361 T cell antigen CD28
Immunoglobulin-like fold
Immunoglobulin-like domain superfamily
Immunoglobulin V-set domain, protein family
wdt:P527 immunoglobulin V-set domain
wdt:P6366 "148125776"
wdt:P637 "NP_001230006"
"NP_001230007"
"NP_006130"
"XP_011510496"
"XP_011510497"
"XP_011510499"
wdt:P638 "1YJD"
"3WA4"
"5AUL"
wdt:P646 "/m/0c1rty"
wdt:P680 protease binding
identical protein binding
protein kinase binding
coreceptor activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein binding
wdt:P681 immunological synapse
integral component of membrane
membrane
external side of plasma membrane
integral component of plasma membrane
cell surface
cytosol
protein complex involved in cell adhesion
plasma membrane
wdt:P682 positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of apoptotic process
positive regulation of gene expression
positive regulation of mitotic nuclear division
positive regulation of protein kinase B signaling
positive regulation of transcription by RNA polymerase II
negative regulation of gene expression
cell surface receptor signaling pathway
negative thymic T cell selection
humoral immune response
T cell activation
T cell receptor signaling pathway
positive regulation of translation
positive regulation of isotype switching to IgG isotypes
positive regulation of T cell proliferation
positive regulation of interleukin-10 production
T cell costimulation
mitigation of host defenses by virus
positive regulation of interleukin-4 production
regulatory T cell differentiation
apoptotic signaling pathway
regulation of T cell proliferation
phosphatidylinositol phosphate biosynthetic process
positive regulation of inflammatory response to antigenic stimulus
positive regulation of alpha-beta T cell proliferation
positive regulation of viral genome replication
immune system process
immune response
regulation of regulatory T cell differentiation
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20CD28%20211856%20x%20at%20fs.png>
wdt:P702 CD28
wdt:P703 man
wdt:P705 "ENSP00000324890"
"ENSP00000363605"
"ENSP00000393648"
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