SHMARQL

dactinomycin

<http://www.wikidata.org/entity/Q186127>

chemical compound
rdfs:label
"dactinomycin"@en
skos:altLabel
"2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-I)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide"@en
"ActD"@en
"Actinomycin C1"@en
"Actinomycin D"@en
"Actinomycin iv"@en
"Cosmegen"@en
"Dactinomicina"@en
"Dactinomycin"@en
"Dactinomycine"@en
"Dactinomycinum"@en
"GNF-Pf-1977"@en
"GNF-Pf-2290"@en
"Meractinomycin"@en
schema:description
"chemical compound"@en
schema:dateModified "2026-09-27T21:22:46+00:00"^^xsd:dateTime
schema:version 2550173185
wikibase:identifiers 55
wikibase:sitelinks 28
wikibase:statements 110
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p:P9989 wd:statement/Q186127-04DDA3F0-75CA-44B9-B152-5858CF351438
p:direct-normalized/P2115 <http://purl.bioontology.org/ontology/NDFRT/N0000146314>
p:direct-normalized/P227 <https://d-nb.info/gnd/4514804-1>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D003609>
p:direct-normalized/P592 <http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL1554>
p:direct-normalized/P6366 <https://makg.org/entity/2776695378>
p:direct-normalized/P661 <http://rdf.chemspider.com/10482167>
p:direct-normalized/P662 <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID457193>
p:direct-normalized/P665 <http://www.kegg.jp/entry/D00214>
p:direct-normalized/P6694 <http://id.nlm.nih.gov/mesh/M0005644>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D03.633.300.200>
<http://id.nlm.nih.gov/mesh/D04.345.566.252>
<http://id.nlm.nih.gov/mesh/D12.644.641.252>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_27666>
p:direct-normalized/P8814 <http://wordnet-rdf.princeton.edu/rdf/id/02680456-n>
wdt:P10245 "a682224"
wdt:P10283 "C2776695378"
wdt:P11089 "573298"
wdt:P11143 "Dactinomycin"
wdt:P11198 "774"
wdt:P11199 "PD003038"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Actinomycin%20D.png>
<http://commons.wikimedia.org/wiki/Special:FilePath/Actinomycin%20D.svg>
wdt:P11901 "dactinomycin"
wdt:P11931 "19722"
wdt:P1417 "science/dactinomycin"
"topic/actinomycin-D"
wdt:P2017 "C[C@@H]1[C@@H](C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N(CC(=O)N([C@H](C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)N[C@H]6[C@H](OC(=O)[C@@H](N(C(=O)CN(C(=O)[C@@H]7CCCN7C(=O)[C@H](NC6=O)C(C)C)C)C)C(C)C)C)N)C"
wdt:P2057 "HMDB0015105"
wdt:P2062 "3220"
wdt:P2065 "009885"
wdt:P2067 1254.628^^xsd:decimal
wdt:P2115 "N0000146314"
wdt:P2175 choriocarcinoma
Ewing sarcoma
uterine cancer
melanoma
connective tissue benign neoplasm
testicular germ cell tumor non-seminomatous
familial retinoblastoma
rhabdomyosarcoma
testicular cancer
Kaposi's sarcoma
hydatidiform mole
neuroblastoma
wdt:P227 "4514804-1"
wdt:P231 "50-76-0"
wdt:P232 "200-063-6"
wdt:P233 "CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C"
wdt:P234 "InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1"
wdt:P235 "RJURFGZVJUQBHK-IIXSONLDSA-N"
wdt:P2566 "100.000.058"
wdt:P267 "L01DA01"
wdt:P274 "C₆₂H₈₆N₁₂O₁₆"
wdt:P279 RJURFGZVJUQBHK-HUZQGMAJSA-N
heterocyclic compound
actinomycin
wdt:P2840 "3053"
"755841"
wdt:P2868 antibiotic
carcinogen
WHO essential medicines
DNA polymerase inhibitors
antineoplastic antibiotics
protein synthesis inhibitor
developmental toxicant
wdt:P2877 "3844"
wdt:P2892 "C0010934"
"C0701095"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID9020031"
wdt:P3345 "3100"
wdt:P3364 2-amino-4,6-dimethyl-3-oxo-N1,N9-bis[(3R,6S,7S,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide
wdt:P3489 US pregnancy category D
Australian pregnancy category D
wdt:P361 response to actinomycin D
cellular response to actinomycin D
wdt:P366 medication
wdt:P373 "Dactinomycin"
wdt:P3780 Cosmegen
wdt:P3827 "actinomycin"
wdt:P486 "D003609"
wdt:P4964 "splash10-001i-1910000000-b4397216681296bde353"
"splash10-03di-2920003011-39d05616f78ee0afd099"
"splash10-0a4i-0102410096-3179cf52b2ed0b4e6890"
wdt:P5008 concrete/abstract disjunction anomalies
wdt:P527 carbon
nitrogen
wdt:P592 "CHEMBL1554"
wdt:P6366 "2776695378"
wdt:P646 "/m/07y3fy"
wdt:P652 "1CC1JFE158"
wdt:P657 "AU1575000"
wdt:P661 "10482167"
wdt:P662 "457193"
wdt:P665 "D00214"
wdt:P6694 "M0005644"
wdt:P672 "D03.633.300.200"
"D04.345.566.252"
"D12.644.641.252"
wdt:P679 "492334"
wdt:P683 "27666"
wdt:P703 Streptomyces
Streptomyces chrysomallus
Streptomyces flavovirens
Streptomyces antibioticus
Streptomyces anulatus
Streptomyces costaricanus
Streptomyces heliomycini
Streptomyces parvulus
Streptomyces sindenensis
Streptomyces flavogriseus
Streptomyces lividans
Streptomyces fradiae
wdt:P715 "DB00970"
wdt:P7524 "actinomycin-d"
wdt:P7746 "NPA007563"
wdt:P7830 "Dactinomycin"
wdt:P8026 LiverTox toxicity likelihood category C
wdt:P8494 "DTXCID5031"
wdt:P8814 "02680456-n"
wdt:P9272 "3628"
wdt:P9635 "83"
wdt:P9989 "DACTINomycin"
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