|
rdfs:label
|
"Ponatinib"@de
"Ponatinib"@it
"Ponatinib"@sh
"Ponatinib"@sl
"Ponatinib"@sr
"Ponatinib"@vi
"Ponatinib"@id
"Ponatinib"@es
"ponatinib"@en
"ponatinib"@fr
"ponatinib"@nl
"ponatinib"@nn
"ponatinib"@zh-hans
"ponatinibe"@pt
"פונטיניב"@he
"بوناتينيب"@ar
"ପୋନାଟିନିବ"@or
"ポナチニブ"@ja
"普纳替尼"@zh-cn
"泊那替尼"@zh
|
|
skos:altLabel
|
"AP 24534"@en
|
|
"AP24534"@en
|
|
"Iclusig®"@en
|
|
"Ponatinib"@en
|
|
"Ponatinibum"@en
|
|
schema:description
|
"cheemesch Verbindung"@lb
"chemical compound"@en
"chemical compound"@en-ca
"chemical compound"@en-gb
"chemická sloučenina"@cs
"chemická zlúčenina"@sk
"chemiese verbinding"@af
"chemische Verbindung"@de
"chemische Verbindung"@de-ch
"chemische verbinding"@nl
"component quimic"@oc
"compositum chemicum"@la
"compost químic"@ca
"composto chimico"@it
"composto químico"@gl
"composto químico"@pt
"composto químico"@pt-br
"composé chimique"@fr
"compuesto quimico"@an
"compuesto químico"@es
"compuestu químicu"@ast
"compus chimic"@ro
"kemia kombinaĵo"@eo
"kemiallinen yhdiste"@fi
"kemisk forbindelse"@da
"kimyasal bileşik"@tr
"kjemisk forbindelse"@nb
"kjemisk sambinding"@nn
"komponim kimik"@sq
"konposatu kimiko"@eu
"senyawa kimia"@id
"związek chemiczny"@pl
"ķīmisks savienojums"@lv
"хемиско соединение"@mk
"химическое соединение"@ru
"хімічна сполука"@uk
"քիմիական միացություն"@hy
"תרכובת"@he
"مركب كيميائي"@ar
"مركب كيميائي"@ary
"کیٖمیٲیی مُرَکَب"@ks
"রাসায়নিক যৌগ"@bn
"രാസസംയുക്തം"@ml
|
|
schema:dateModified
|
"2026-11-04T10:13:12+00:00"^^xsd:dateTime
|
|
schema:version
|
2564647088
|
|
wikibase:identifiers
|
42
|
|
wikibase:sitelinks
|
15
|
|
wikibase:statements
|
64
|
|
p:P10245
|
wd:statement/Q198728-60a2dc94-4141-8343-f014-87978823ff8c
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|
p:P10283
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wd:statement/Q198728-29BF5B84-7628-4E41-B784-658654E0754A
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|
p:P11089
|
wd:statement/Q198728-92DD438B-F8E4-4E7F-9556-98C65A0CB964
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|
p:P11143
|
wd:statement/Q198728-CD1DCF92-B6D2-4FC4-9F17-941CF4DF644C
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|
p:P11198
|
wd:statement/Q198728-5C3D7C75-FCBC-47EA-9B97-E9676578FE24
|
|
p:P11199
|
wd:statement/Q198728-9A702D5E-5656-4A88-AB2E-9CC37A3ED13E
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|
p:P117
|
wd:statement/Q198728-2494B4D0-138C-4B38-83FE-04E3EBF1A72F
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|
p:P129
|
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|
|
wd:statement/Q198728-38B3985D-0AF0-4DA1-89F8-1918A9760422
|
|
wd:statement/Q198728-391A3A6C-126E-4D68-B833-83E9D545579C
|
|
wd:statement/Q198728-477E4593-439F-45A7-817E-8C76248E79DA
|
|
wd:statement/Q198728-B588C9CB-6B7F-4AE7-94C3-C19D7BB7B645
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|
p:P1579
|
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|
p:P2057
|
wd:statement/Q198728-1A1228D7-9487-4D54-B3AB-BF070AF0FD4C
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|
p:P2062
|
wd:statement/Q198728-CD9F4A38-8C0A-4788-BF8D-AC7CAAF46FE7
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|
p:P2067
|
wd:statement/Q198728-A01B54FC-4684-4D9E-9B4F-089BC1F3F595
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|
p:P2115
|
wd:statement/Q198728-DFF8480A-CB69-4EBA-A6E3-90505982A404
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|
p:P2175
|
wd:statement/Q198728-2E8951C8-C082-41EF-B99D-57409D80B6F7
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|
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|
p:P2275
|
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|
wd:statement/Q198728-05B5F08D-5B0D-41AB-9EAB-E0207061F100
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|
p:P233
|
wd:statement/Q198728-B6AD45A4-5B1B-492E-835D-DA2E0BAE9FFB
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|
p:P234
|
wd:statement/Q198728-8BAF9758-C536-4DD6-8AA3-887BF96AE003
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|
p:P235
|
wd:statement/Q198728-02CCEE22-2ECB-4ECB-9B86-8B47A6D2410D
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|
p:P267
|
wd:statement/Q198728-75F9A0F5-3987-4FE8-9FFB-5016AE701B43
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p:P274
|
wd:statement/Q198728-E385B305-43E0-48F7-A408-2B3E48849728
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|
p:P279
|
wd:statement/Q198728-BD88C009-54BA-4213-AC6C-BC7A457DCA6B
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|
p:P2868
|
wd:statement/Q198728-3833D54C-970F-4AB0-9893-4F605F1B2AFA
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|
wd:statement/Q198728-48429186-C0D3-4822-9CC9-BB6C9FDA7C9B
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|
wd:statement/Q198728-7EDC87A3-3CA1-477B-91ED-8F59F06D5D99
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|
p:P2877
|
wd:statement/Q198728-F7F7D8DA-06BE-411A-88EE-C4A9C218AC8E
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|
p:P2892
|
wd:statement/Q198728-F12A5C0F-EA5A-4B84-9A9F-A8BC92E691D4
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|
p:P31
|
wd:statement/Q198728-8253F324-3A5C-4D51-AA5E-FDF6A663E8A9
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|
p:P3117
|
wd:statement/Q198728-8321AB7E-4156-4531-9E93-D3346CA1FCE8
|
|
p:P3345
|
wd:statement/Q198728-21248773-42C1-468D-B461-C111FB7D1331
|
|
p:P3489
|
wd:statement/Q198728-8485199C-0F17-4326-8D5F-0FE66637FAF7
|
|
p:P3636
|
wd:statement/Q198728-8AA52B33-C8C6-414B-ACDA-A6BE9D714C1D
|
|
p:P366
|
wd:statement/Q198728-6CB01ADE-0401-450C-B9EB-CA16FE8750B4
|
|
p:P373
|
wd:statement/Q198728-D1F1002C-5395-4AA0-935A-1FC7179E12F7
|
|
p:P3780
|
wd:statement/Q198728-50C9E09F-503A-4EB3-A36F-B6BC54C7D826
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|
p:P486
|
wd:statement/Q198728-34B051BF-360E-40F5-B78A-A132C768D9F1
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|
p:P4964
|
wd:statement/Q198728-0D8E614B-162D-4B92-B423-C22A949BCAA3
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|
p:P592
|
wd:statement/Q198728-67A37701-A0B2-49B3-8FBD-9DA55108CF9D
|
|
p:P595
|
wd:statement/Q198728-98C15D50-5ADF-4C59-BAED-621895330115
|
|
p:P6366
|
wd:statement/Q198728-762ADFE3-38ED-4AD9-9D1E-3136AC0DA625
|
|
p:P638
|
wd:statement/Q198728-1A3FC4C1-0E87-4B92-B00D-EB8C95E07504
|
|
wd:statement/Q198728-46691DA3-DDA3-4236-8EAA-71C156E324D2
|
|
wd:statement/Q198728-5DAB7514-EA6B-478B-B122-DCE40BC4FD1D
|
|
wd:statement/Q198728-77368E56-7E8B-44FC-ADE7-DBEE0ACA92D8
|
|
wd:statement/Q198728-8F0F8F64-E5D0-4B8B-9431-E62E5552B5EE
|
|
wd:statement/Q198728-A26260C3-FB42-4084-A417-6819E278F8A0
|
|
wd:statement/Q198728-A6A47B1E-6AAB-459B-8160-7911B5164DA6
|
|
wd:statement/Q198728-C09533CA-93E7-4045-91F5-2DA59236A656
|
|
wd:statement/Q198728-C8D4CB11-A2E2-4E44-AAFC-0E41E3B9EB4C
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|
wd:statement/Q198728-E849B59C-4A00-4E51-A481-BDEA87457A3B
|
|
p:P646
|
wd:statement/Q198728-E72E50E8-9797-44F4-A40D-C14DB73C5B38
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|
p:P652
|
wd:statement/Q198728-6B1A9A34-CBCC-4F6D-B5A8-797366F7838C
|
|
p:P661
|
wd:statement/Q198728-49E4F734-E7BB-499D-A4D2-05148D6F1527
|
|
p:P662
|
wd:statement/Q198728-75394E09-1E67-4DDB-85E7-B7F25737DEAF
|
|
p:P665
|
wd:statement/Q198728-C8FC4483-0CFE-4C3E-B18E-D56946CB0B77
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|
p:P683
|
wd:statement/Q198728-6160C9D2-933A-490A-9AAD-A25A99B277B8
|
|
p:P715
|
wd:statement/Q198728-B8CA1EB5-82A1-4346-9CFE-E426C8A985FD
|
|
p:P8494
|
wd:statement/Q198728-4D290E87-BB3A-4324-866A-028D852E13E6
|
|
p:P9989
|
wd:statement/Q198728-2698701F-F5D5-4494-A2A4-55CC2B41E70A
|
|
p:direct-normalized/P2115
|
<http://purl.bioontology.org/ontology/NDFRT/N0000186141>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/C545373>
|
|
p:direct-normalized/P592
|
<http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL1171837>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/2780381907>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/3IK3>
|
|
<https://rdf.wwpdb.org/pdb/3OXZ>
|
|
<https://rdf.wwpdb.org/pdb/3ZOS>
|
|
<https://rdf.wwpdb.org/pdb/4C8B>
|
|
<https://rdf.wwpdb.org/pdb/4QRC>
|
|
<https://rdf.wwpdb.org/pdb/4TYJ>
|
|
<https://rdf.wwpdb.org/pdb/4U0I>
|
|
<https://rdf.wwpdb.org/pdb/4UXQ>
|
|
<https://rdf.wwpdb.org/pdb/4V01>
|
|
<https://rdf.wwpdb.org/pdb/4V04>
|
|
p:direct-normalized/P661
|
<http://rdf.chemspider.com/24747381>
|
|
p:direct-normalized/P662
|
<http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24826799>
|
|
p:direct-normalized/P665
|
<http://www.kegg.jp/entry/D09950>
|
|
p:direct-normalized/P683
|
<http://purl.obolibrary.org/obo/CHEBI_78543>
|
|
wdt:P10245
|
"a613029"
|
|
wdt:P10283
|
"C2780381907"
|
|
wdt:P11089
|
"109182"
|
|
wdt:P11143
|
"Ponatinib"
|
|
wdt:P11198
|
"4716"
|
|
wdt:P11199
|
"PD004100"
|
|
wdt:P117
|
<http://commons.wikimedia.org/wiki/Special:FilePath/Ponatinib.svg>
|
|
wdt:P129
|
Cyclin dependent kinase 19
|
|
ret proto-oncogene
|
|
Cyclin dependent kinase 8
|
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
|
wdt:P1579
|
"12923700"
|
|
wdt:P2057
|
"HMDB0240214"
|
|
wdt:P2062
|
"8184"
|
|
wdt:P2067
|
532.22^^xsd:decimal
|
|
wdt:P2115
|
"N0000186141"
|
|
wdt:P2175
|
gastrointestinal stromal tumor
|
|
acute myeloid leukemia
|
|
wdt:P2275
|
"ponatinib"@en
|
|
wdt:P231
|
"943319-70-8"
|
|
wdt:P233
|
"CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5"
|
|
wdt:P234
|
"InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39)"
|
|
wdt:P235
|
"PHXJVRSECIGDHY-UHFFFAOYSA-N"
|
|
wdt:P267
|
"L01XE24"
|
|
wdt:P274
|
"C₂₉H₂₇F₃N₆O"
|
|
wdt:P279
|
unsaturated compound
|
|
wdt:P2868
|
antineoplastic
|
|
protein kinase inhibitors
|
|
tyrosine-kinase inhibitor
|
|
wdt:P2877
|
"589260"
|
|
wdt:P2892
|
"C2987417"
|
|
wdt:P31
|
type of chemical entity
|
|
wdt:P3117
|
"DTXSID50241426"
|
|
wdt:P3345
|
"1364347"
|
|
wdt:P3489
|
US pregnancy category D
|
|
wdt:P3636
|
"0LI"
|
|
wdt:P366
|
medication
|
|
wdt:P373
|
"Ponatinib"
|
|
wdt:P3780
|
Iclusig
|
|
wdt:P486
|
"C545373"
|
|
wdt:P4964
|
"splash10-03e9-0290150000-ab2ecf1ddb48e116ad86"
|
|
wdt:P592
|
"CHEMBL1171837"
|
|
wdt:P595
|
"5890"
|
|
wdt:P6366
|
"2780381907"
|
|
wdt:P638
|
"3IK3"
|
|
"3OXZ"
|
|
"3ZOS"
|
|
"4C8B"
|
|
"4QRC"
|
|
"4TYJ"
|
|
"4U0I"
|
|
"4UXQ"
|
|
"4V01"
|
|
"4V04"
|
|
wdt:P646
|
"/m/0gvsf55"
|
|
wdt:P652
|
"4340891KFS"
|
|
wdt:P661
|
"24747381"
|
|
wdt:P662
|
"24826799"
|
|
wdt:P665
|
"D09950"
|
|
wdt:P683
|
"78543"
|
|
wdt:P715
|
"DB08901"
|
|
wdt:P8494
|
"DTXCID50163917"
|
|
wdt:P9989
|
"PONATinib"
|
