|
rdfs:label
|
"Colony stimulating factor 1 receptor"@en
"Colony stimulating factor 1 receptor"@nl
|
|
skos:altLabel
|
"2.7.10.1"@en
|
|
"CD115 antigen"@en
|
|
"CSF-1 receptor"@en
|
|
"CSF-1-R"@en
|
|
"CSF-1R"@en
|
|
"CSF1R"@en
|
|
"FMS proto-oncogene"@en
|
|
"M-CSF-R"@en
|
|
"McDonough feline sarcoma viral (v-fms) oncogene homolog"@en
|
|
"macrophage colony stimulating factor I receptor"@en
|
|
"macrophage colony-stimulating factor 1 receptor"@en
|
|
"proto-oncogene c-Fms"@en
|
|
schema:description
|
"Protein in Homo sapiens"@de
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in Colony stimulating factor 1 receptor"@nl
"protèin"@ace
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
|
|
schema:dateModified
|
"2023-12-03T10:59:49+00:00"^^xsd:dateTime
|
|
schema:version
|
2022915438
|
|
wikibase:identifiers
|
28
|
|
wikibase:sitelinks
|
0
|
|
wikibase:statements
|
144
|
|
p:P129
|
wd:statement/Q21100975-2AEF163F-F478-4D51-94DC-6264ED7043A5
|
|
wd:statement/Q21100975-33C5C7A7-012D-4D58-B551-274AE069598E
|
|
wd:statement/Q21100975-4383F70F-0683-43B7-86B1-8C19950BF35F
|
|
wd:statement/Q21100975-84AA853D-8217-48BB-94C8-DE30553D32FD
|
|
wd:statement/Q21100975-9F619DED-6189-4335-A203-A6FE4D2974D2
|
|
wd:statement/Q21100975-FE079C25-F27C-43FD-98D1-197E39AA8CFE
|
|
p:P31
|
wd:statement/Q21100975-8D0850F0-8744-4B7F-AAF4-23BCA5B64B4C
|
|
p:P352
|
wd:statement/Q21100975-730151C1-2B59-41DF-B9AA-F1CF57C77363
|
|
p:P361
|
wd:statement/Q21100975-1D0331A5-470C-40B0-84F1-537A124A02EE
|
|
wd:statement/Q21100975-1FFA6DC2-09E2-44DB-ACDD-5A69E1B09DFC
|
|
wd:statement/Q21100975-20F9D873-D2AF-476E-A6E4-C14F59753C4F
|
|
wd:statement/Q21100975-39FA3BC4-D324-4E14-A3A5-79A159987A3C
|
|
wd:statement/Q21100975-597B4854-7C3E-463D-B96C-AA562192C3B1
|
|
wd:statement/Q21100975-945BEECD-91B3-493D-A3DF-A457136ECFF4
|
|
wd:statement/Q21100975-AA18433F-71DB-432B-B5EE-CB17E4BA16F6
|
|
wd:statement/Q21100975-AD4340EE-4461-40A9-A09F-CC3A6F296B11
|
|
wd:statement/Q21100975-B5A63303-E06B-4DE9-8390-232FA6D8DE38
|
|
wd:statement/Q21100975-CB8186E4-A398-432E-8DC6-96A463D8E1F6
|
|
wd:statement/Q21100975-CE69BE17-596F-4AFF-8E57-0E97A381BBA5
|
|
wd:statement/Q21100975-D920B1E7-C3A1-4512-982F-502DDF8B1919
|
|
wd:statement/Q21100975-F6F95F8B-6A69-4839-AF12-63BE9ACC2E27
|
|
wd:statement/Q21100975-FDDC7EEA-2972-46F9-BEF9-518488EB5D5D
|
|
p:P527
|
wd:statement/Q21100975-082F7E29-BFC0-4AB0-8193-F441EE1EF5D9
|
|
wd:statement/Q21100975-1E1985B7-4F08-4FC3-8F2D-927994BABEA2
|
|
wd:statement/Q21100975-292A648C-86CC-49A5-8D59-62E32E6F7760
|
|
wd:statement/Q21100975-3B1205C8-CC66-419C-A840-278E17E3336F
|
|
wd:statement/Q21100975-4D7CD9F5-4CC5-4CF6-8DCB-3BEC03A491A8
|
|
wd:statement/Q21100975-5153B937-617B-4C22-AA2D-740ED61F0912
|
|
wd:statement/Q21100975-9E0F7ED2-4766-4C8C-B941-0C63286BFDD8
|
|
wd:statement/Q21100975-AABCA544-45E5-4556-9479-71ABBA6DD82C
|
|
wd:statement/Q21100975-C1E7FCF3-7D52-4EF0-93D4-5D771010C78B
|
|
wd:statement/Q21100975-EA334E4D-FC9A-4482-BF2C-E9AF7DCD0218
|
|
p:P591
|
wd:statement/Q21100975-579F97E4-E8F4-4372-B78D-F5256C10C4F8
|
|
p:P637
|
wd:statement/Q21100975-17424546-8157-4DC5-8CBD-A21758171D75
|
|
wd:statement/Q21100975-49D1B618-38AB-48DF-9BC2-90A68C3FF061
|
|
wd:statement/Q21100975-7303A6EA-59B0-488F-B8FE-7DE7338DAFEA
|
|
wd:statement/Q21100975-DA2DA5B7-5A6C-43FB-B79E-56FA97ECD62A
|
|
wd:statement/Q21100975-F68BE959-CFB3-4D5C-B9BB-A4965D1E6912
|
|
p:P638
|
wd:statement/Q21100975-000418FA-CEB1-4541-9F86-571A61422830
|
|
wd:statement/Q21100975-32E1E749-520C-4EF1-AF17-CF3DB0E2CE01
|
|
wd:statement/Q21100975-39FA05B5-2841-47F7-BB2C-CE57E40D6904
|
|
wd:statement/Q21100975-4ECE87E1-084C-4302-8A25-5ADDC2DAA703
|
|
wd:statement/Q21100975-74EFBE51-ECDD-4A4E-8657-F39C37287852
|
|
wd:statement/Q21100975-7B9AB2A6-F50B-436E-B69B-7FD84ED38BBB
|
|
wd:statement/Q21100975-8103645A-B3E1-4B46-9755-D4ECA86027C4
|
|
wd:statement/Q21100975-895F23DA-9736-4E73-8390-215503C22829
|
|
wd:statement/Q21100975-90E72EC2-31AD-4123-B6DC-EC4C87DEB747
|
|
wd:statement/Q21100975-A7FA1CEE-4644-4742-8DC6-4EC6CE51A1A9
|
|
wd:statement/Q21100975-AB3D2076-B829-4AA0-B993-AB2D35756F04
|
|
wd:statement/Q21100975-BE905DF6-3CC4-4AF9-9467-024FFC52ADBE
|
|
wd:statement/Q21100975-C99C2AB5-0A96-4B06-8F8A-B88C4938BFD2
|
|
wd:statement/Q21100975-DCE19153-F2CB-431D-8C12-8219938BBF59
|
|
wd:statement/Q21100975-EDDCFFD6-ADB9-43BE-A465-32C4E18C25C1
|
|
wd:statement/Q21100975-F04C7BD3-6FD1-4349-82C8-4F3D59A655DB
|
|
wd:statement/Q21100975-F4A06D40-E17C-4E4A-BEED-C5FA19596F42
|
|
p:P680
|
wd:statement/Q21100975-071C186E-97C0-4B8A-B799-C76762E550D7
|
|
wd:statement/Q21100975-127B6FBB-3862-4D9C-841F-ECA4A22A5595
|
|
wd:statement/Q21100975-217EC178-A2F5-45CB-8793-037CC2A30020
|
|
wd:statement/Q21100975-339CAB67-86F5-4ED5-9681-67E5CA50E21A
|
|
wd:statement/Q21100975-3C52D612-CE55-4EBB-9EF6-278D79351FFC
|
|
wd:statement/Q21100975-3F79B50E-BFDF-41BC-A01C-C5298CDFA665
|
|
wd:statement/Q21100975-542A7A0F-D165-4566-BC7E-1FB71EDB0508
|
|
wd:statement/Q21100975-55896992-6641-4748-93F8-AD3F2D18E527
|
|
wd:statement/Q21100975-82692360-015C-4576-9C1E-D8F83096CB53
|
|
wd:statement/Q21100975-A9D555E1-8D3D-4225-832D-06EAD6FB405F
|
|
wd:statement/Q21100975-ACCD8CE3-83DF-4A93-AFAB-B91BA00BB193
|
|
wd:statement/Q21100975-ADB66384-AE5C-4161-B4EA-26D927905BDF
|
|
wd:statement/Q21100975-B57B5534-208D-432A-936F-EFBF8AABF3E8
|
|
wd:statement/Q21100975-C4E3DA30-DE47-4F34-8CF8-FD88F31E282E
|
|
wd:statement/Q21100975-D57C8C49-8FFF-42CA-B17D-E26FFB71FD14
|
|
wd:statement/Q21100975-D7417F9F-420F-4793-AE9A-A474449A5856
|
|
wd:statement/Q21100975-E9E9CB10-CE05-4814-88E8-689083AFC6C8
|
|
p:P681
|
wd:statement/Q21100975-2C6D6FBB-2FFB-47B0-A1F1-39C579B8060C
|
|
wd:statement/Q21100975-312E407C-A017-4A71-87B9-D7502390D1D3
|
|
wd:statement/Q21100975-3C0A1D2F-7548-4E77-AB16-1B4B44D80BD0
|
|
wd:statement/Q21100975-49079970-A978-4F02-B9EB-F3E2179A583F
|
|
wd:statement/Q21100975-64B75CAF-3B7F-4503-86B5-EEE707FB85B9
|
|
wd:statement/Q21100975-7D7B0D59-FE22-4ECD-985B-99B4CC8C3202
|
|
wd:statement/Q21100975-81A50241-375E-427C-815C-239C44ACACB4
|
|
wd:statement/Q21100975-8ED56C80-0C84-4FC0-AE7E-56393CFCDC3D
|
|
wd:statement/Q21100975-ACC7A051-508D-4DB4-A4F1-1D046C6EDBE2
|
|
wd:statement/Q21100975-B46FCA05-56B8-41F4-A5B7-00BD2D1FDD15
|
|
wd:statement/Q21100975-DE1163F0-EAB3-4AE3-9B00-275354B7CF9C
|
|
wd:statement/Q21100975-E62A0586-8087-4DE0-A475-5C67298E7569
|
|
p:P682
|
wd:statement/Q21100975-04BF95A7-CF06-411C-81CB-3BFE6958807E
|
|
wd:statement/Q21100975-09675E06-CCB2-434E-8696-0B6A2BF52CBC
|
|
wd:statement/Q21100975-0B2B4693-7DC7-4D42-A792-5AE6D0FA6D2E
|
|
wd:statement/Q21100975-0D5B2551-F645-4E1B-B3C3-905888B186BC
|
|
wd:statement/Q21100975-16637A2B-7570-4612-9648-F8F3AC6CBF09
|
|
wd:statement/Q21100975-17BFCD11-276E-48E1-AF19-EA4ABEBCBE9B
|
|
wd:statement/Q21100975-218B3AB2-1FDE-41EB-9149-AF3A63FB3369
|
|
wd:statement/Q21100975-24F35F54-5165-416F-9090-9E66143A8D1E
|
|
wd:statement/Q21100975-26970C08-B39F-4C2B-BF7E-A7C4E4A60E59
|
|
wd:statement/Q21100975-329B0019-47C6-44ED-8069-F8A927869363
|
|
wd:statement/Q21100975-3EE151E8-83A7-4041-8751-F7A107E6EDF6
|
|
wd:statement/Q21100975-44C8EB0C-F29A-4356-822F-5B7F078BDA87
|
|
wd:statement/Q21100975-4ACD39EA-1E7B-4583-B361-0CA5733444B9
|
|
wd:statement/Q21100975-4B8E353F-6C9A-4C9A-96DA-115B2B923091
|
|
wd:statement/Q21100975-4C0CD727-AF37-42BF-82AA-1510BFD072DE
|
|
wd:statement/Q21100975-5AA8BB62-60D3-42F1-AFAD-70B17D4E21AC
|
|
wd:statement/Q21100975-5EB5E59A-4A2F-48AE-9E32-4DB007D3A6DA
|
|
wd:statement/Q21100975-66928E40-18ED-4B6D-963E-7ED025A36487
|
|
wd:statement/Q21100975-6CECCACC-D388-4575-B308-16AC8F6C61F7
|
|
wd:statement/Q21100975-710C16C9-6A49-4EE7-B546-B03886A461CC
|
|
wd:statement/Q21100975-75BBE060-F6A5-461B-8685-E3130D850942
|
|
wd:statement/Q21100975-7962A414-1079-4126-A3E0-9BECC544E014
|
|
wd:statement/Q21100975-7EB9DF21-6222-490B-9BFF-7FBF319116C4
|
|
wd:statement/Q21100975-8149FDA7-36DB-4707-BC3B-0180C34CF08F
|
|
wd:statement/Q21100975-81638894-122F-463A-95B9-DA44C2BCDBCF
|
|
wd:statement/Q21100975-8295F3EE-208A-478B-9B05-9AED7B4C646F
|
|
wd:statement/Q21100975-85C6AA9D-1B24-4547-BEF4-6B393DFB53F4
|
|
wd:statement/Q21100975-869FE9F3-B9FC-4E94-A92E-3C72E4B325F3
|
|
wd:statement/Q21100975-94DD69AC-DDEA-4891-9D53-56AC81A0E773
|
|
wd:statement/Q21100975-9C5A6C8E-A9B5-44AE-AB88-FEDDBF398754
|
|
wd:statement/Q21100975-A0F0C942-2ABA-46D2-BF1F-12A5371A381D
|
|
wd:statement/Q21100975-A5EE1507-A15C-404F-AC72-364FD8DD55E3
|
|
wd:statement/Q21100975-A842867F-71B7-4F15-99B8-E190BF98FA17
|
|
wd:statement/Q21100975-ABA31F4F-C896-4B8D-A029-1FAC04E8F89B
|
|
wd:statement/Q21100975-B16FC1C0-AA39-47AB-B7B2-D48BEE2A0CBB
|
|
wd:statement/Q21100975-B6A31E62-EA04-457A-9776-197913C6C281
|
|
wd:statement/Q21100975-B8ACEA84-62A6-476A-BFA8-55A21AE31BC8
|
|
wd:statement/Q21100975-B9C6DA91-6A3F-43E5-801E-4CBBE0D574A9
|
|
wd:statement/Q21100975-B9D7EA8D-D153-465B-BE97-6E9010BD08E7
|
|
wd:statement/Q21100975-BA01D1A2-7783-4C07-90BB-50064986A75A
|
|
wd:statement/Q21100975-C1EB9112-54AD-4EAF-BE90-CDD55087D80D
|
|
wd:statement/Q21100975-CAA3A495-D46C-4FCB-874D-80BE21284A74
|
|
wd:statement/Q21100975-CDFD6361-D2E6-40FB-8E3B-06C22A422823
|
|
wd:statement/Q21100975-D16034D7-B053-43C5-A2BC-C572C84D9E39
|
|
wd:statement/Q21100975-D2058621-B485-424C-AF3F-D5253DD91DA3
|
|
wd:statement/Q21100975-D4836520-04BC-4A28-A99D-EFF9B7EB4ECE
|
|
wd:statement/Q21100975-DF17A2F7-66B6-4A4C-91E0-2D229F52C0C6
|
|
wd:statement/Q21100975-E01D1F8A-FDB0-47B4-8B6C-EDFD43A4AAA0
|
|
wd:statement/Q21100975-E3EC1F64-C009-47CC-8FBB-A47A99BCFD98
|
|
wd:statement/Q21100975-EC720E36-7A3E-4048-9D36-75BF1A51C49D
|
|
wd:statement/Q21100975-EEF801BA-304A-477C-A61F-DE7C868727D8
|
|
wd:statement/Q21100975-F5629096-FDD2-4F57-9E56-4E2EF7F31F0E
|
|
wd:statement/Q21100975-FA103780-DCCB-4A16-A104-EE425062B7F3
|
|
p:P702
|
wd:statement/Q21100975-FAEB3AE6-49C0-4E53-9A78-69A425307212
|
|
p:P703
|
wd:statement/Q21100975-E1EBAF6E-7EE7-4C28-BADA-A6F2B0DCE5E5
|
|
p:P705
|
wd:statement/Q21100975-58985E8D-FE36-44F2-AEC9-910525967697
|
|
wd:statement/Q21100975-929B989B-A4F3-4A39-9FB0-D9E1C4B03AA3
|
|
wd:statement/Q21100975-AC8EA417-0A07-4038-AF88-38533B9F0772
|
|
wd:statement/Q21100975-EF9436A7-026F-475C-A6D5-6EC668561F2E
|
|
wd:statement/Q21100975-F7BF88AC-747C-4E22-8370-635D86E95162
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P07333>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001275634>
|
|
<http://purl.uniprot.org/refseq/NP_001336665>
|
|
<http://purl.uniprot.org/refseq/NP_001362249>
|
|
<http://purl.uniprot.org/refseq/NP_001362250>
|
|
<http://purl.uniprot.org/refseq/NP_005202>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/2I0V>
|
|
<https://rdf.wwpdb.org/pdb/2I0Y>
|
|
<https://rdf.wwpdb.org/pdb/2I1M>
|
|
<https://rdf.wwpdb.org/pdb/2OGV>
|
|
<https://rdf.wwpdb.org/pdb/3BEA>
|
|
<https://rdf.wwpdb.org/pdb/3DPK>
|
|
<https://rdf.wwpdb.org/pdb/3KRJ>
|
|
<https://rdf.wwpdb.org/pdb/3KRL>
|
|
<https://rdf.wwpdb.org/pdb/3LCD>
|
|
<https://rdf.wwpdb.org/pdb/3LCO>
|
|
<https://rdf.wwpdb.org/pdb/4DKD>
|
|
<https://rdf.wwpdb.org/pdb/4HW7>
|
|
<https://rdf.wwpdb.org/pdb/4LIQ>
|
|
<https://rdf.wwpdb.org/pdb/4R7H>
|
|
<https://rdf.wwpdb.org/pdb/4R7I>
|
|
<https://rdf.wwpdb.org/pdb/4WRL>
|
|
<https://rdf.wwpdb.org/pdb/4WRM>
|
|
wdt:P129
|
Emactuzumab
|
|
enmd-981693
|
|
cediranib
|
|
crenolanib
|
|
linifanib
|
|
pazopanib
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P07333"
|
|
wdt:P361
|
Protein kinase-like domain superfamily
|
|
Macrophage colony-stimulating factor 1 receptor
|
|
Immunoglobulin-like fold
|
|
Immunoglobulin-like domain superfamily
|
|
Tyrosine-protein kinase, catalytic domain, protein family
|
|
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
|
|
Protein kinase domain, protein family
|
|
Immunoglobulin domain, protein family
|
|
Immunoglobulin subtype 2, protein family
|
|
immunoglobulin-like domain, protein family
|
|
immunoglobulin subtype, protein family
|
|
Tyrosine-protein kinase, receptor class III, conserved site, protein family
|
|
Tyrosine-protein kinase, active site, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P527
|
tyrosine-protein kinase, catalytic domain
|
|
tyrosine-protein kinase, active site
|
|
serine-threonine/tyrosine-protein kinase, catalytic domain
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
immunoglobulin domain
|
|
tyrosine-protein kinase, receptor class III, conserved site
|
|
immunoglobulin subtype 2
|
|
immunoglobulin-like domain
|
|
immunoglobulin subtype
|
|
wdt:P591
|
"2.7.10.1"
|
|
wdt:P637
|
"NP_001275634"
|
|
"NP_001336665"
|
|
"NP_001362249"
|
|
"NP_001362250"
|
|
"NP_005202"
|
|
wdt:P638
|
"2I0V"
|
|
"2I0Y"
|
|
"2I1M"
|
|
"2OGV"
|
|
"3BEA"
|
|
"3DPK"
|
|
"3KRJ"
|
|
"3KRL"
|
|
"3LCD"
|
|
"3LCO"
|
|
"4DKD"
|
|
"4HW7"
|
|
"4LIQ"
|
|
"4R7H"
|
|
"4R7I"
|
|
"4WRL"
|
|
"4WRM"
|
|
wdt:P680
|
protein homodimerization activity
|
|
ATP binding
|
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protein kinase activity
|
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transferase activity
|
|
nucleotide binding
|
|
protein phosphatase binding
|
|
kinase activity
|
|
protein tyrosine kinase activity
|
|
transmembrane receptor protein tyrosine kinase activity
|
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transmembrane signaling receptor activity
|
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cytokine binding
|
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protein binding
|
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macrophage colony-stimulating factor receptor activity
|
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receptor tyrosine kinase
|
|
wdt:P681
|
integral component of membrane
|
|
membrane
|
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intracellular membrane-bounded organelle
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nucleoplasm
|
|
integral component of plasma membrane
|
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receptor complex
|
|
cell surface
|
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CSF1-CSF1R complex
|
|
plasma membrane
|
|
cytoplasm
|
|
wdt:P682
|
peptidyl-tyrosine phosphorylation
|
|
positive regulation of protein tyrosine kinase activity
|
|
negative regulation of cell population proliferation
|
|
negative regulation of apoptotic process
|
|
positive regulation of cell population proliferation
|
|
multicellular organism development
|
|
positive regulation of cell migration
|
|
positive regulation of MAPK cascade
|
|
response to ischemia
|
|
regulation of cell shape
|
|
positive regulation of protein phosphorylation
|
|
inflammatory response
|
|
positive regulation of ERK1 and ERK2 cascade
|
|
osteoclast differentiation
|
|
positive regulation of cell motility
|
|
positive regulation of protein serine/threonine kinase activity
|
|
cytokine-mediated signaling pathway
|
|
cellular response to cytokine stimulus
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
|
phosphatidylinositol-mediated signaling
|
|
ruffle organization
|
|
regulation of actin cytoskeleton reorganization
|
|
mammary gland duct morphogenesis
|
|
hematopoietic progenitor cell differentiation
|
|
monocyte differentiation
|
|
macrophage differentiation
|
|
negative regulation of signal transduction
|
|
regulation of bone resorption
|
|
positive regulation of tyrosine phosphorylation of STAT protein
|
|
cell-cell junction maintenance
|
|
olfactory bulb development
|
|
immune system process
|
|
phosphatidylinositol metabolic process
|
|
cell population proliferation
|
|
axon guidance
|
|
cell differentiation
|
|
positive regulation by host of viral process
|
|
cellular response to macrophage colony-stimulating factor stimulus
|
|
macrophage colony-stimulating factor signaling pathway
|
|
forebrain neuron differentiation
|
|
microglial cell proliferation
|
|
phosphorylation
|
|
protein autophosphorylation
|
|
innate immune response
|
|
protein phosphorylation
|
|
signal transduction
|
|
hemopoiesis
|
|
wdt:P702
|
CSF1R
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000286301"
|
|
"ENSP00000421174"
|
|
"ENSP00000422212"
|
|
"ENSP00000427545"
|
|
"ENSP00000445282"
|