|
rdfs:label
|
"Dual specificity tyrosine phosphorylation regulated kinase 1A"@en
"Dual specificity tyrosine phosphorylation regulated kinase 1A"@nl
|
|
skos:altLabel
|
"DYRK1A"@en
|
|
"HP86"@en
|
|
"MNB/DYRK protein kinase"@en
|
|
"MNBH"@en
|
|
"dual specificity YAK1-related kinase"@en
|
|
"dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A"@en
|
|
"dual specificity tyrosine-phosphorylation-regulated kinase 1A"@en
|
|
"hMNB"@en
|
|
"mnb protein kinase homolog hp86"@en
|
|
"protein kinase minibrain homolog"@en
|
|
"serine/threonine kinase MNB"@en
|
|
"serine/threonine-specific protein kinase"@en
|
|
schema:description
|
"Protein in Homo sapiens"@de
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in Dual specificity tyrosine phosphorylation regulated kinase 1A"@nl
"protèin"@ace
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
|
|
schema:dateModified
|
"2026-07-24T05:41:15+00:00"^^xsd:dateTime
|
|
schema:version
|
2521951806
|
|
wikibase:identifiers
|
53
|
|
wikibase:sitelinks
|
0
|
|
wikibase:statements
|
113
|
|
p:P31
|
wd:statement/Q21101022-8EFC9B9C-9713-4DCB-9908-B69B337575E2
|
|
p:P352
|
wd:statement/Q21101022-E37B0801-F01F-43C9-AA04-F6016E5D0052
|
|
p:P361
|
wd:statement/Q21101022-1E4C7DC2-15D0-419A-A629-EA8BCABE28A3
|
|
wd:statement/Q21101022-3307CA2F-AC0D-4FE9-B67D-EA009FFE9D5A
|
|
wd:statement/Q21101022-38C8DC2A-EF6F-4AC6-9C65-A9B8B28B8DA5
|
|
wd:statement/Q21101022-76A90C42-F745-4A62-937C-40BF8A923C5E
|
|
wd:statement/Q21101022-F9F319C9-4FDC-49FF-9850-8B0B984FE22F
|
|
p:P527
|
wd:statement/Q21101022-4C685ECE-28D0-45BD-AA04-29EFF64BB327
|
|
wd:statement/Q21101022-A98292DD-64DB-4ED8-A955-A72A38657EB0
|
|
wd:statement/Q21101022-F8F58D7C-13E9-4208-BBAC-E8887CC41E0C
|
|
p:P591
|
wd:statement/Q21101022-63B35F5B-8637-436B-8DFC-5FC1E6C205DF
|
|
wd:statement/Q21101022-D2E737BD-9B8C-4E85-86E5-DD73DF295B45
|
|
p:P637
|
wd:statement/Q21101022-10EDE005-E64D-4CFD-ABAE-91B3F30E563B
|
|
wd:statement/Q21101022-34B6304B-6EF8-4E4D-BF25-936CD234C23F
|
|
wd:statement/Q21101022-3954945A-1EC2-425E-B38D-A01FE21BA6ED
|
|
wd:statement/Q21101022-3AD6FDE3-6E41-4E4C-99A9-2B8D726E457C
|
|
wd:statement/Q21101022-46CB9841-C419-4FCC-8AD5-5AF3255B39AB
|
|
wd:statement/Q21101022-4923ABA3-5239-4006-BC47-4882EAD2A46D
|
|
wd:statement/Q21101022-4E043F49-1528-4119-B651-220938C6F56E
|
|
wd:statement/Q21101022-50DF5AA3-C36E-42F5-AC60-2B0991F47511
|
|
wd:statement/Q21101022-5D2536AF-67E1-42E7-BA7C-6D998E7BD09C
|
|
wd:statement/Q21101022-67F83D05-747F-4F1C-9FF4-BCFB290EEFDB
|
|
wd:statement/Q21101022-97CCB02B-4F9F-4B79-8280-6BA44A267FA6
|
|
wd:statement/Q21101022-A347E81C-A299-43E3-9733-41499F41A496
|
|
wd:statement/Q21101022-DB17FE82-AD0C-4807-B2DB-DF33D1467BE7
|
|
wd:statement/Q21101022-DFC5AF4A-F658-4D12-9C3F-943C65E97A5E
|
|
wd:statement/Q21101022-F119A390-0D28-4D48-88DD-F80ED03B224B
|
|
p:P638
|
wd:statement/Q21101022-00B90791-193B-481C-84AF-52AAD07E9E62
|
|
wd:statement/Q21101022-012AAFB7-184D-4CC8-8EF7-95974D10C06A
|
|
wd:statement/Q21101022-0FFC43A7-EF9F-43DD-980A-02128C5F793C
|
|
wd:statement/Q21101022-35FA5C78-DA81-4E47-9B0A-C4C3B097C3F8
|
|
wd:statement/Q21101022-38C5D8A7-126D-49D1-BD5C-99F55489628C
|
|
wd:statement/Q21101022-4565831B-BFCF-4914-9B77-D08ACA027EBA
|
|
wd:statement/Q21101022-5C1FA014-1B11-4401-A545-77DD01C7170F
|
|
wd:statement/Q21101022-62BB4FA8-FC60-4CB0-80F4-19D492522641
|
|
wd:statement/Q21101022-7C0E5AC5-D029-431E-9192-B0F79AE85C04
|
|
wd:statement/Q21101022-7EBF82C7-5379-46A0-B453-5E69DCE257FF
|
|
wd:statement/Q21101022-803B4E63-7BBC-435A-9B73-958E395FD3FF
|
|
wd:statement/Q21101022-9BDC42DE-10A6-4947-8F44-5F472A9CF337
|
|
wd:statement/Q21101022-BFCCB0A2-B7D9-4B77-941B-B4A1909303F9
|
|
wd:statement/Q21101022-CED25EFC-ACD7-41BF-8907-021CB9D9A33F
|
|
wd:statement/Q21101022-CEFEB880-2BB6-4718-B7DC-9CD5840DE9ED
|
|
wd:statement/Q21101022-D429BD5C-509A-4D4A-9408-C5DFE7F28B51
|
|
wd:statement/Q21101022-E56D1AD2-80C5-444F-BA92-9EFEE66931F9
|
|
wd:statement/Q21101022-F10BC423-3FBD-4425-B205-5E42374AF7B6
|
|
wd:statement/Q21101022-F756DA1B-6185-4EDB-932F-7C3E23802924
|
|
p:P680
|
wd:statement/Q21101022-06389FB4-0DA6-4E12-BD1C-6C306195FF3B
|
|
wd:statement/Q21101022-07102623-AEF7-4C2E-8D4D-5604FD8EB320
|
|
wd:statement/Q21101022-115395F8-C6B2-4734-B77E-57F4DE9AB843
|
|
wd:statement/Q21101022-3D8DB6CC-9D1F-4CDB-A7BB-DFC80C157223
|
|
wd:statement/Q21101022-4DFF9CDC-6C66-40DC-8A79-0DC1494B02A8
|
|
wd:statement/Q21101022-54DC13DE-26FA-495E-B5F4-35AB2A1DB102
|
|
wd:statement/Q21101022-59C7EA49-E443-4254-9BF5-082DD36E3AF6
|
|
wd:statement/Q21101022-5C2E7B5B-DDFD-4C3C-AB83-FF8C0565B3E6
|
|
wd:statement/Q21101022-7690FEC9-06E2-444E-B777-722D3700F585
|
|
wd:statement/Q21101022-7E9A97F7-C2CF-444F-B951-3B538561C734
|
|
wd:statement/Q21101022-8091F414-5FB1-4A3A-8B74-CCA2E0867C1C
|
|
wd:statement/Q21101022-99EC4031-FE61-43AE-8D0F-58CBD72A66C5
|
|
wd:statement/Q21101022-9B96FDD5-B1A7-4650-8DBC-A075978D7531
|
|
wd:statement/Q21101022-B70A1D8C-07E7-4A49-ACCF-9C50B75DA83E
|
|
wd:statement/Q21101022-C85F1207-3D6A-4EB4-BEEE-C1B0DEAC6083
|
|
wd:statement/Q21101022-DB0B0524-A1BD-4BCB-B8BF-2C9099830B4E
|
|
wd:statement/Q21101022-F6AD1F47-B528-490F-8F95-B1BA68630BE9
|
|
p:P681
|
wd:statement/Q21101022-2391B771-F7EC-46BB-A6EE-BCFA155685E1
|
|
wd:statement/Q21101022-2884484B-B3D3-4A92-858D-90641512B62C
|
|
wd:statement/Q21101022-327A9E15-4C96-4BE4-9FFA-9F00A8ED04E1
|
|
wd:statement/Q21101022-4758822F-66AF-4EF0-9024-4E22DFC108A3
|
|
wd:statement/Q21101022-59449929-1F10-430C-9EB6-5F19AC761D83
|
|
wd:statement/Q21101022-5DACCB97-8C55-48ED-A217-27A58BCD14C0
|
|
wd:statement/Q21101022-7BCBF3F9-4084-4862-BAE7-DDECACB2D6D3
|
|
wd:statement/Q21101022-86BCF920-F81E-4B13-9D63-98E09E02AE82
|
|
wd:statement/Q21101022-9B404B8E-2D42-43F9-B829-F37D8B39131E
|
|
wd:statement/Q21101022-D7260550-EE54-42E6-88EE-888F26231CF1
|
|
p:P682
|
wd:statement/Q21101022-102AE58A-DA38-4D28-AB4D-3DE87F814621
|
|
wd:statement/Q21101022-43B28AB5-75D9-4C95-ACC1-7C4AFB7374F3
|
|
wd:statement/Q21101022-534B7A67-199F-4F82-8892-B2DDA8874A58
|
|
wd:statement/Q21101022-61FDF428-4629-4978-9A12-6EA79D41E119
|
|
wd:statement/Q21101022-738D4C34-1512-4825-B935-2B5DBE151BF5
|
|
wd:statement/Q21101022-8DB2772A-538C-441F-A51C-4AED2B124592
|
|
wd:statement/Q21101022-A17DFD02-314A-4F0D-8D7F-33180D78FBE8
|
|
wd:statement/Q21101022-A74A61C4-10ED-4BA3-BE88-B06D931B17D2
|
|
wd:statement/Q21101022-A764EF83-9089-4BAE-9FEE-CCA40E860F2C
|
|
wd:statement/Q21101022-AABAD88C-165B-4B24-AF8F-5952B69D34B1
|
|
wd:statement/Q21101022-B20DEBEA-CEC3-4ADD-81D4-CF4BA455D1A3
|
|
wd:statement/Q21101022-B393A0EC-748E-4B5A-B68A-CAC9030ECC17
|
|
wd:statement/Q21101022-CB41BF89-C57D-47F0-B786-C37846FD7003
|
|
wd:statement/Q21101022-CCF70451-7340-4F1A-8792-764824CDFC24
|
|
wd:statement/Q21101022-CD06B30A-95D6-4FEE-B4A2-1EFD8C65D776
|
|
wd:statement/Q21101022-CDAA1CCB-37AC-471F-A941-AA6813FAD711
|
|
wd:statement/Q21101022-F5917FEB-E6C9-4E78-9168-14424B38D43D
|
|
wd:statement/Q21101022-F803FCCD-2493-420C-A923-E960A8992B09
|
|
wd:statement/Q21101022-F8537895-EDA3-47A4-AD3B-959BE3BC65BA
|
|
wd:statement/Q21101022-F8FD18C3-4C39-4ED2-B54C-0110AE77A125
|
|
p:P702
|
wd:statement/Q21101022-1D6310AB-70F7-423F-A939-A7780066D567
|
|
p:P703
|
wd:statement/Q21101022-5D15F955-6BAD-4B1E-80C9-E3B9C2B73361
|
|
p:P705
|
wd:statement/Q21101022-0EDF0DBB-6E47-4865-BF20-1683C8493A44
|
|
wd:statement/Q21101022-0F65EF6A-F0B7-4B40-AE4B-53B31D849F47
|
|
wd:statement/Q21101022-25AF821B-8F6A-49B9-BD3D-6591245B3BCB
|
|
wd:statement/Q21101022-291115DA-5071-4C56-B0DA-3F79909EEF7D
|
|
wd:statement/Q21101022-34613A98-DFAB-4789-8784-9E3324CD25F2
|
|
wd:statement/Q21101022-487D5E78-615F-492A-9A98-710F283CD887
|
|
wd:statement/Q21101022-58326F0E-E2F5-4DDA-B0F2-55C25FD5B596
|
|
wd:statement/Q21101022-63A462D1-6BE7-42AD-9F7C-0334D6A39184
|
|
wd:statement/Q21101022-793AE3D0-7C3B-4F31-98EA-64D3C826D07D
|
|
wd:statement/Q21101022-9BC6EDF6-9A10-4AB0-9ED1-95251432ECAE
|
|
wd:statement/Q21101022-9CBAA849-00FC-4F2E-AB2C-2572FE5A6D19
|
|
wd:statement/Q21101022-A4D2E8BD-E23E-46BA-8842-88B878D31185
|
|
wd:statement/Q21101022-A567208E-9BD6-44AC-8B2D-AFCC004DFB92
|
|
wd:statement/Q21101022-B5A45F7C-519C-43E5-AB93-362234513D46
|
|
wd:statement/Q21101022-D3200F3F-43B2-4F3F-BF5D-D069615CCA62
|
|
wd:statement/Q21101022-DA9F8B63-794B-4F8F-86E1-B0BC438A4C87
|
|
wd:statement/Q21101022-E03592D6-6857-46E6-A612-20E76C7D51BF
|
|
wd:statement/Q21101022-F600D351-3D02-48A5-9F23-03409D74BBB6
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/Q13627>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001334650>
|
|
<http://purl.uniprot.org/refseq/NP_001334651>
|
|
<http://purl.uniprot.org/refseq/NP_001334652>
|
|
<http://purl.uniprot.org/refseq/NP_001387>
|
|
<http://purl.uniprot.org/refseq/NP_567824>
|
|
<http://purl.uniprot.org/refseq/NP_569120>
|
|
<http://purl.uniprot.org/refseq/NP_569122>
|
|
<http://purl.uniprot.org/refseq/XP_005260990>
|
|
<http://purl.uniprot.org/refseq/XP_006724039>
|
|
<http://purl.uniprot.org/refseq/XP_006724040>
|
|
<http://purl.uniprot.org/refseq/XP_006724041>
|
|
<http://purl.uniprot.org/refseq/XP_011527785>
|
|
<http://purl.uniprot.org/refseq/XP_016883773>
|
|
<http://purl.uniprot.org/refseq/XP_016883775>
|
|
<http://purl.uniprot.org/refseq/XP_024307825>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/2VX3>
|
|
<https://rdf.wwpdb.org/pdb/2WO6>
|
|
<https://rdf.wwpdb.org/pdb/3ANQ>
|
|
<https://rdf.wwpdb.org/pdb/3ANR>
|
|
<https://rdf.wwpdb.org/pdb/4AZE>
|
|
<https://rdf.wwpdb.org/pdb/4MQ1>
|
|
<https://rdf.wwpdb.org/pdb/4MQ2>
|
|
<https://rdf.wwpdb.org/pdb/4NCT>
|
|
<https://rdf.wwpdb.org/pdb/4YLJ>
|
|
<https://rdf.wwpdb.org/pdb/4YLK>
|
|
<https://rdf.wwpdb.org/pdb/4YLL>
|
|
<https://rdf.wwpdb.org/pdb/4YU2>
|
|
<https://rdf.wwpdb.org/pdb/5A3X>
|
|
<https://rdf.wwpdb.org/pdb/5A4E>
|
|
<https://rdf.wwpdb.org/pdb/5A4L>
|
|
<https://rdf.wwpdb.org/pdb/5A4Q>
|
|
<https://rdf.wwpdb.org/pdb/5A4T>
|
|
<https://rdf.wwpdb.org/pdb/5A54>
|
|
<https://rdf.wwpdb.org/pdb/5AIK>
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"Q13627"
|
|
wdt:P361
|
Protein kinase-like domain superfamily
|
|
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
|
|
Protein kinase domain, protein family
|
|
Serine/threonine-protein kinase, active site, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P527
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
serine/threonine-protein kinase, active site
|
|
wdt:P591
|
"2.7.11.23"
|
|
"2.7.12.1"
|
|
wdt:P637
|
"NP_001334650"
|
|
"NP_001334651"
|
|
"NP_001334652"
|
|
"NP_001387"
|
|
"NP_567824"
|
|
"NP_569120"
|
|
"NP_569122"
|
|
"XP_005260990"
|
|
"XP_006724039"
|
|
"XP_006724040"
|
|
"XP_006724041"
|
|
"XP_011527785"
|
|
"XP_016883773"
|
|
"XP_016883775"
|
|
"XP_024307825"
|
|
wdt:P638
|
"2VX3"
|
|
"2WO6"
|
|
"3ANQ"
|
|
"3ANR"
|
|
"4AZE"
|
|
"4MQ1"
|
|
"4MQ2"
|
|
"4NCT"
|
|
"4YLJ"
|
|
"4YLK"
|
|
"4YLL"
|
|
"4YU2"
|
|
"5A3X"
|
|
"5A4E"
|
|
"5A4L"
|
|
"5A4Q"
|
|
"5A4T"
|
|
"5A54"
|
|
"5AIK"
|
|
wdt:P680
|
protein serine/threonine kinase activity
|
|
protein serine/threonine/tyrosine kinase activity
|
|
identical protein binding
|
|
ATP binding
|
|
protein kinase activity
|
|
transferase activity
|
|
nucleotide binding
|
|
tau protein binding
|
|
kinase activity
|
|
protein tyrosine kinase activity
|
|
protein self-association
|
|
non-membrane spanning protein tyrosine kinase activity
|
|
tau-protein kinase activity
|
|
protein binding
|
|
wdt:P681
|
dendrite
|
|
nucleoplasm
|
|
nuclear speck
|
|
cytoskeleton
|
|
axon
|
|
nucleus
|
|
ribonucleoprotein complex
|
|
cytoplasm
|
|
wdt:P682
|
nervous system development
|
|
peptidyl-tyrosine phosphorylation
|
|
peptidyl-serine phosphorylation
|
|
negative regulation of microtubule polymerization
|
|
peptidyl-threonine phosphorylation
|
|
regulation of alternative mRNA splicing, via spliceosome
|
|
viral process
|
|
negative regulation of DNA damage response, signal transduction by p53 class mediator
|
|
peptidyl-serine autophosphorylation
|
|
peptidyl-tyrosine autophosphorylation
|
|
circadian rhythm
|
|
positive regulation of protein deacetylation
|
|
negative regulation of mRNA splicing, via spliceosome
|
|
positive regulation of RNA splicing
|
|
amyloid-beta formation
|
|
phosphorylation
|
|
protein autophosphorylation
|
|
protein phosphorylation
|
|
wdt:P702
|
DYRK1A
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000340373"
|
|
"ENSP00000342690"
|
|
"ENSP00000381929"
|
|
"ENSP00000381932"
|
|
"ENSP00000398483"
|
|
"ENSP00000412269"
|
|
"ENSP00000493627"
|
|
"ENSP00000493653"
|
|
"ENSP00000494536"
|
|
"ENSP00000494544"
|
|
"ENSP00000494572"
|
|
"ENSP00000494698"
|
|
"ENSP00000494897"
|
|
"ENSP00000495571"
|
|
"ENSP00000495596"
|
|
"ENSP00000495632"
|
|
"ENSP00000495908"
|
|
"ENSP00000496748"
|