INS

protein-coding gene in Homo sapiens
rdfs:label
"INS"@en
skos:altLabel
"IDDM"@en
"IDDM1"@en
"IDDM2"@en
"ILPR"@en
"IRDN"@en
"MODY10"@en
"PNDM4"@en
"insulin"@en
schema:description
"protein-coding gene in Homo sapiens"@en
schema:dateModified "2026-07-19T04:00:05+00:00"^^xsd:dateTime
schema:version 2519481814
wikibase:identifiers 17
wikibase:sitelinks 1
wikibase:statements 132
p:P1057 wd:statement/Q21163221-2B0ED0C8-2762-457A-B78F-21EAB354EA42
p:P18 wd:statement/Q21163221-65f8cea2-493c-f308-c35f-a1fc33070549
p:P1814 wd:statement/Q21163221-520A640C-3630-4011-8F78-1960E57475CA
p:P1889 wd:statement/Q21163221-43879210-DFA6-4923-83AD-DF9D89009E4E
p:P2293 wd:statement/Q21163221-48E222E7-B33A-47C8-8E1A-B8779952F7DA
wd:statement/Q21163221-635FDB33-3333-4A62-92A7-C64F00C8F9C1
wd:statement/Q21163221-A6B8EDFE-F821-4B4C-82DD-866134C1BE6D
wd:statement/Q21163221-A6EA33C3-033F-47E9-B1DA-2B9EF27E6C64
wd:statement/Q21163221-AE548A04-7DAB-4E02-938B-79574DA5F2C6
wd:statement/Q21163221-E98BD556-EBF3-45DB-9A86-4D6484D2012E
p:P2548 wd:statement/Q21163221-3679BEFA-40EA-4041-8034-5761DDDE91C0
p:P279 wd:statement/Q21163221-058EA378-737F-493D-AC24-AC95D8328DC1
p:P2888 wd:statement/Q21163221-D6EB5662-F812-4338-8666-63C1CA327365
p:P2892 wd:statement/Q21163221-2AACC119-A524-46FB-9E66-08235383DB68
p:P31 wd:statement/Q21163221-DE6801F1-AB05-4E62-8C43-08FD6135D0E1
p:P351 wd:statement/Q21163221-C809D1E9-AE99-441A-A411-F5BB49D0DE9B
p:P353 wd:statement/Q21163221-CFA07B9A-59F0-43BE-B3F8-2E8EE4E8D67E
p:P354 wd:statement/Q21163221-16E76ED8-F05E-43A1-9DE2-4D6DAE3852B7
p:P373 wd:statement/Q21163221-284C9BCA-AE1A-4ADB-8CF6-63E359DD45DE
p:P4196 wd:statement/Q21163221-D758A9A3-D43F-4E4D-8CBD-AEC83C694CF0
p:P492 wd:statement/Q21163221-707B2C45-2F07-4D4B-A470-A1A59D88F1C7
p:P5572 wd:statement/Q21163221-0955A544-979F-4527-9344-C1035162F398
wd:statement/Q21163221-175C44DC-ADE8-499E-A407-F2B4EB541003
wd:statement/Q21163221-3EA66C1C-B1E2-4D3A-867F-BA7AF9147D94
wd:statement/Q21163221-68C9C277-FEB3-4DA5-9CE0-F9B7CAD921A1
wd:statement/Q21163221-C01B7D07-C699-497C-9B8E-33FA11E13B58
wd:statement/Q21163221-C95000EE-D4BF-4DCA-AA85-03DB72E999ED
wd:statement/Q21163221-CCF12DAA-24D5-4710-91FB-3A6327A83BD2
wd:statement/Q21163221-CE429DA1-2B9B-4F8F-B8CF-D0EE1EA6A32E
wd:statement/Q21163221-FA2450D2-36F3-43F7-99CC-AF7326B4576E
wd:statement/Q21163221-FE9CB861-9438-48F8-9E48-6513D43EAD7E
p:P593 wd:statement/Q21163221-51C00051-A015-4D8C-92E6-D11DDCDFE6ED
p:P594 wd:statement/Q21163221-4A73E367-69B6-4988-98EC-07766F8512B7
p:P639 wd:statement/Q21163221-6370FC14-E8EE-4900-86B5-BDC11CE85C60
wd:statement/Q21163221-8717C745-686F-422B-A807-B0958B8D0B4C
wd:statement/Q21163221-F590D38B-39F9-4450-B82E-2ED8C31CE6FE
wd:statement/Q21163221-FF62E36C-771C-4077-9D9D-5875171767D4
p:P644 wd:statement/Q21163221-407DE5DE-19A5-4873-A845-7869C2F84D5F
wd:statement/Q21163221-FF193B1E-F230-432F-8B31-C4F91101F818
p:P645 wd:statement/Q21163221-3CD5ED40-FD65-4518-A11A-E13451BBD294
wd:statement/Q21163221-C84250C7-337B-4874-A281-B787E924176D
p:P682 wd:statement/Q21163221-0261BC4E-636E-4B82-B478-CB55D561DE5C
wd:statement/Q21163221-099197B3-AC2A-48A4-8C7C-188588AFFE1D
wd:statement/Q21163221-0A845499-8702-47AD-BF4E-C1EEB066A02A
wd:statement/Q21163221-0D1C8BB7-F291-4B26-9875-D29007A204AC
wd:statement/Q21163221-1014A785-FAE7-4261-BE5B-D6EE9FC1C7B5
wd:statement/Q21163221-11581006-8C30-46EB-86D7-92C1CFAEDE64
wd:statement/Q21163221-1178B490-7515-4FCA-9DAA-66DDBD047545
wd:statement/Q21163221-12F8997E-48DC-42D4-AF88-59482E81B19E
wd:statement/Q21163221-145647B5-4521-4E20-9B0D-F5763748C5F4
wd:statement/Q21163221-14EF9A9B-6067-4057-8973-BD0005CC8C34
wd:statement/Q21163221-18750796-1AB6-4FE3-A297-5052903372FB
wd:statement/Q21163221-1B1D29C1-0238-43C8-866F-AC092F10C8AB
wd:statement/Q21163221-1BAFDD50-F3C5-4922-A26A-47EA6DD8E34E
wd:statement/Q21163221-1E323BC5-3FFB-4DBE-84A9-586FC6684CF9
wd:statement/Q21163221-208D88D3-09C3-4DB8-B532-443AB84E37EE
wd:statement/Q21163221-26AF06EB-3ACD-4932-8800-C37952BD40AB
wd:statement/Q21163221-297AADC6-B1E2-4855-8C7A-9CD0CBB47069
wd:statement/Q21163221-2D8DCF81-4578-4CF9-9F8A-07E7F0D58A7C
wd:statement/Q21163221-2D8DCFCA-4962-4576-AED0-5D2621309C2E
wd:statement/Q21163221-3595FF34-65EA-4B1D-95DD-CFF35E613F83
wd:statement/Q21163221-376A5DEF-691D-4529-A6ED-B9629AAF92BD
wd:statement/Q21163221-37E576E0-CB68-4A0F-B29A-0BC85FE55C21
wd:statement/Q21163221-3E74D9E9-A5C4-48DB-8F2C-F4BC654AFBEC
wd:statement/Q21163221-40E026AC-6179-48C6-9F25-3FD596D3B964
wd:statement/Q21163221-40ED78E4-D73A-4FC9-9DFD-EBD038F43421
wd:statement/Q21163221-44DF5AF0-A4A6-48A3-9669-752DF51609C6
wd:statement/Q21163221-4E8B8CFE-7D38-42F1-8077-FC716614A754
wd:statement/Q21163221-56C7021B-1A74-48A7-914D-C01B34B66F0D
wd:statement/Q21163221-57BF12E3-9CD4-4C2B-A347-5211CA833C43
wd:statement/Q21163221-58A7C473-6377-4234-B840-4206FC8573C2
wd:statement/Q21163221-5C034CA8-A7E1-4962-89E6-884AC3D5A0DA
wd:statement/Q21163221-70CAC613-CBF1-4027-84A2-AC6962740C57
wd:statement/Q21163221-8B522BE5-46D3-414C-851F-F34D76C978BD
wd:statement/Q21163221-8C947EC5-3A9A-4B82-A0AE-9B50150FC99E
wd:statement/Q21163221-90E34370-5737-417A-8C62-8F112014A893
wd:statement/Q21163221-910953D7-DAE2-4940-8536-E29B87A05701
wd:statement/Q21163221-91B2EE11-8983-43DD-B573-1C0A9A17BEF5
wd:statement/Q21163221-94567AC2-EF77-4F6E-94BC-C43E2766A714
wd:statement/Q21163221-9B147B11-D0D1-43AD-A0F4-5D51FAEB627A
wd:statement/Q21163221-A005B99D-ABF2-46EA-9244-B54DD8B905EF
wd:statement/Q21163221-A03EFCD6-CF93-466B-917B-9A627C16ABB7
wd:statement/Q21163221-A3287361-B848-4B39-AEA2-9A06747F23CD
wd:statement/Q21163221-A3F253B9-FD96-4264-8E19-776F854999F6
wd:statement/Q21163221-A42C4C1B-0EF8-4BF6-9C3C-2721EA8C2B51
wd:statement/Q21163221-A609ECBC-8545-4442-9137-FC4219BD3AB5
wd:statement/Q21163221-A86919A6-11AD-4717-839C-FB57F572892C
wd:statement/Q21163221-AB80BC8E-8BB3-449B-B036-1BB2EF36F560
wd:statement/Q21163221-AD0721A9-BF4F-4965-8F8C-00EEF5B0D686
wd:statement/Q21163221-B3F1997C-FF12-4955-AE5E-219D8329A9FD
wd:statement/Q21163221-B5C0127B-56E7-41D3-A05C-7CD1882C7637
wd:statement/Q21163221-C7908269-4619-489F-B5AA-F820AB29C703
wd:statement/Q21163221-C8BCE4D8-0745-45E6-9A06-CD97BAB79255
wd:statement/Q21163221-C9DA9D34-6C9C-46A3-BE54-E09282C9333D
wd:statement/Q21163221-CBCCC9E5-F75F-4692-B4EA-D2BDABA84542
wd:statement/Q21163221-CBEB8F4A-6916-41C8-906A-8E965D186F0D
wd:statement/Q21163221-CCA7723F-1023-441E-A345-6DCB90C1C6F1
wd:statement/Q21163221-CCFC8079-F272-46F5-863A-3D52A2589D32
wd:statement/Q21163221-CE7BD303-61F4-4CF2-BE6C-43FAD10F0333
wd:statement/Q21163221-D6BE7182-7BD3-40FA-9E15-5C3E2B1681DD
wd:statement/Q21163221-DE314097-F0C3-4AB5-B0C8-FCABB6C4ADAC
wd:statement/Q21163221-E3F6DC3B-20E3-4AFB-987C-630026ABFC93
wd:statement/Q21163221-E5B716D0-A526-4C5E-9871-1BF19295FAC6
wd:statement/Q21163221-E7FAE4BB-AD66-41BC-9A23-A71867A2F946
wd:statement/Q21163221-F1B27F62-4F0B-45E1-87A1-5C90B9069BE2
wd:statement/Q21163221-F1E2141D-ECBB-4D5F-9FEA-723590EF08A2
wd:statement/Q21163221-F49EB11D-B748-4B36-B412-B2E25527958B
wd:statement/Q21163221-F7E70117-8DCD-4A9D-8B8C-09CA878355DA
wd:statement/Q21163221-F92BD20E-7CD9-47DA-8969-2C99ED01CA77
wd:statement/Q21163221-FA400F2D-3CA4-4F77-8658-ACE07ADBF6E0
p:P684 wd:statement/Q21163221-1AFFB1E4-C5D5-4C99-9835-54B3E62D6C75
wd:statement/Q21163221-55BA8148-585A-409C-B95F-14A894D28374
wd:statement/Q21163221-5F5043B9-7BEC-4EF4-ACE4-9F086E2AFB5E
wd:statement/Q21163221-6AE12575-5FC0-4CA5-BE10-D5B9A3490C4F
wd:statement/Q21163221-BCB30001-8CAC-4D41-86B3-CB86D7D8EE8B
p:P688 wd:statement/Q21163221-104e23b7-438e-318b-62dc-ffe022371139
wd:statement/Q21163221-4F95131E-0867-4EC1-9FFC-979FE09DAF41
wd:statement/Q21163221-5D10231A-0BB0-4CF9-A2D2-8B802C76E8A6
wd:statement/Q21163221-5a789a9d-48af-ffa2-a162-c7e5bdbde40c
wd:statement/Q21163221-6c0dadd8-4de3-6836-abff-7f7ebc208444
wd:statement/Q21163221-9b53e06a-4cf1-a1ce-7371-7fd241e5e088
p:P692 wd:statement/Q21163221-03885B0D-195A-4082-8181-D94B5E2AE921
p:P703 wd:statement/Q21163221-10F138BE-B69F-46B8-8CEC-23C3E395539B
p:P704 wd:statement/Q21163221-0960BBF5-EAFA-4EBF-9524-4BCA7A189E94
wd:statement/Q21163221-1E032F62-6797-490D-B9B0-127D87EC5D0F
wd:statement/Q21163221-A6D612BD-650E-4159-B5FC-931A1B0D21E0
wd:statement/Q21163221-DDB6C023-2767-49AC-9913-EFC1FD27E97E
wd:statement/Q21163221-E19FC5F4-457E-4D63-B0AD-4AC31C80DEF1
p:P737 wd:statement/Q21163221-64dba38c-4bd6-3133-b5ac-3a2f5be46e02
p:P7502 wd:statement/Q21163221-C9BBCF4E-0A7D-48E7-8893-662A6AEEE3C0
p:P8408 wd:statement/Q21163221-14569815-C5B5-4507-B200-2ED759F7914C
p:P935 wd:statement/Q21163221-63A747F9-2F4F-49DD-B797-6B0A0A7EABC1
p:direct-normalized/P351 <http://purl.uniprot.org/geneid/3630>
p:direct-normalized/P594 <http://rdf.ebi.ac.uk/resource/ensembl/ENSG00000254647>
p:direct-normalized/P704 <http://rdf.ebi.ac.uk/resource/ensembl/ENST00000250971>
<http://rdf.ebi.ac.uk/resource/ensembl/ENST00000381330>
<http://rdf.ebi.ac.uk/resource/ensembl/ENST00000397262>
<http://rdf.ebi.ac.uk/resource/ensembl/ENST00000421783>
<http://rdf.ebi.ac.uk/resource/ensembl/ENST00000512523>
p:direct-normalized/P8408 <http://kbpedia.org/kko/rc/Insulin>
wdt:P1057 human chromosome 11
wdt:P18 <http://commons.wikimedia.org/wiki/Special:FilePath/Insulin%20struct.png>
wdt:P1814 "インシュリン"
wdt:P1889 preproinsulin
wdt:P2293 permanent neonatal diabetes mellitus
type 1 diabetes mellitus 2
maturity-onset diabetes of the young type 9
maturity-onset diabetes of the young type 10
rare genetic diabetes mellitus
Hyperproinsulinemia
wdt:P2548 reverse strand
wdt:P279 protein-coding gene
wdt:P2888 <http://identifiers.org/ncbigene/3630>
wdt:P2892 "C1337112"
wdt:P31 gene
wdt:P351 "3630"
wdt:P353 "INS"
wdt:P354 "6081"
wdt:P373 "Insulin"
wdt:P4196 "11p15.5"
wdt:P492 "176730"
wdt:P5572 beta cell
body of pancreas
right lobe of liver
left uterine tube
right adrenal cortex
left adrenal cortex
ectocervix
Descending thoracic aorta
right adrenal gland
left adrenal gland
wdt:P593 "173"
wdt:P594 "ENSG00000254647"
wdt:P639 "NM_000207"
"NM_001185097"
"NM_001185098"
"NM_001291897"
wdt:P644 "2159779"
"2181009"
wdt:P645 "2161221"
"2182571"
wdt:P682 positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of long-term synaptic potentiation
regulation of transcription, DNA-templated
positive regulation of cell population proliferation
positive regulation of gene expression
positive regulation of DNA replication
MAPK cascade
negative regulation of acute inflammatory response
glucose metabolic process
regulation of cellular amino acid metabolic process
acute-phase response
G protein-coupled receptor signaling pathway
cell-cell signaling
insulin receptor signaling pathway
regulation of transmembrane transporter activity
positive regulation of cell growth
positive regulation of cell migration
positive regulation of protein autophosphorylation
activation of protein kinase B activity
positive regulation of protein metabolic process
negative regulation of protein oligomerization
regulation of protein localization
negative regulation of NAD(P)H oxidase activity
negative regulation of protein catabolic process
glucose homeostasis
positive regulation of MAPK cascade
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
negative regulation of gluconeogenesis
positive regulation of glycogen biosynthetic process
negative regulation of glycogen catabolic process
positive regulation of glycolytic process
positive regulation of mitotic nuclear division
negative regulation of proteolysis
negative regulation of fatty acid metabolic process
positive regulation of glucose import
positive regulation of insulin receptor signaling pathway
alpha-beta T cell activation
positive regulation of lipid biosynthetic process
regulation of protein secretion
negative regulation of protein secretion
negative regulation of lipid catabolic process
positive regulation of nitric-oxide synthase activity
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling
fatty acid homeostasis
negative regulation of respiratory burst involved in inflammatory response
positive regulation of respiratory burst
positive regulation of peptide hormone secretion
positive regulation of brown fat cell differentiation
negative regulation of feeding behavior
regulation of synaptic plasticity
regulation of signaling receptor activity
positive regulation of protein localization to nucleus
endoplasmic reticulum to Golgi vesicle-mediated transport
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
wound healing
regulation of protein localization to plasma membrane
positive regulation of nitric oxide mediated signal transduction
negative regulation of reactive oxygen species biosynthetic process
response to L-arginine
positive regulation of dendritic spine maintenance
cognition
neuron projection maintenance
carbohydrate metabolic process
signal transduction
wdt:P684 Ins2
Ins1
Ins1
Ins2
ins
wdt:P688 Insulin, isoform CRA_a
C-peptide
proinsulin
insulin A chain
insulin B chain
preproinsulin
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20INS%20206598%20at%20fs.png>
wdt:P703 man
wdt:P704 "ENST00000250971"
"ENST00000381330"
"ENST00000397262"
"ENST00000421783"
"ENST00000512523"
wdt:P737 glucose
wdt:P7502 "Insulin-36K3"
wdt:P8408 "Insulin"
wdt:P935 "Insulin"
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