SHMARQL

topiramate

<http://www.wikidata.org/entity/Q221174>

an anticonvulsant (antiepilepsy) drug
rdfs:label
"topiramate"@en
skos:altLabel
"2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate"@en
"2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate"@en
"TPM"@en
"Topamax"@en
"[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate"@en
schema:description
"an anticonvulsant (antiepilepsy) drug"@en
schema:dateModified "2026-10-27T05:38:40+00:00"^^xsd:dateTime
schema:version 2561331655
wikibase:identifiers 58
wikibase:sitelinks 37
wikibase:statements 125
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p:P9272 wd:statement/Q221174-D4821E76-2EA7-4C68-B07A-E69B6D2D6684
p:direct-normalized/P2115 <http://purl.bioontology.org/ontology/NDFRT/N0000148493>
p:direct-normalized/P244 <http://id.loc.gov/authorities/names/sh97000684>
p:direct-normalized/P4527 <http://data.parliament.uk/terms/510289>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D000077236>
p:direct-normalized/P592 <http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL220492>
p:direct-normalized/P6366 <https://makg.org/entity/2777683783>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/3HKU>
<https://rdf.wwpdb.org/pdb/3LXE>
p:direct-normalized/P661 <http://rdf.chemspider.com/4447672>
p:direct-normalized/P662 <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5284627>
p:direct-normalized/P665 <http://www.kegg.jp/entry/D00537>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D09.947.875.359.250.500>
<http://id.nlm.nih.gov/mesh/D09.947.875.465.354.500>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_63631>
wdt:P10245 "a697012"
wdt:P10283 "C2777683783"
wdt:P11089 "128687"
wdt:P11143 "Topiramate"
wdt:P11198 "2706"
wdt:P11199 "PD000722"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Topiramat.svg>
<http://commons.wikimedia.org/wiki/Special:FilePath/Topiramate.svg>
wdt:P129 Glutamate ionotropic receptor AMPA type subunit 3
Glutamate ionotropic receptor kainate type subunit 1
Glutamate ionotropic receptor kainate type subunit 3
Glutamate ionotropic receptor kainate type subunit 4
Gamma-aminobutyric acid type A receptor subunit delta
Gamma-aminobutyric acid type A receptor subunit gamma2
Gamma-aminobutyric acid type A receptor subunit beta3
Gamma-aminobutyric acid type A receptor subunit beta2
Gamma-aminobutyric acid type A receptor subunit gamma1
Gamma-aminobutyric acid type A receptor subunit theta
Glutamate ionotropic receptor kainate type subunit 2
Glutamate ionotropic receptor kainate type subunit 5
Gamma-aminobutyric acid type A receptor subunit beta1
Gamma-aminobutyric acid type A receptor subunit alpha3
Glutamate ionotropic receptor AMPA type subunit 1
Carbonic anhydrase 12
sodium voltage-gated channel alpha subunit 1
Sodium voltage-gated channel alpha subunit 10
Carbonic anhydrase 2
Carbonic anhydrase 7
Sodium voltage-gated channel alpha subunit 2
Sodium voltage-gated channel alpha subunit 3
Carbonic anhydrase 1
Sodium voltage-gated channel alpha subunit 5
Carbonic anhydrase 4
Gamma-aminobutyric acid type A receptor subunit alpha4
Sodium voltage-gated channel alpha subunit 4
Sodium voltage-gated channel alpha subunit 9
Sodium voltage-gated channel alpha subunit 11
wdt:P13591 "concept/4726b6b8-efe7-4369-a816-b36e8ab09959"
wdt:P1417 "topic/topiramate"
wdt:P1552 bitterness
wdt:P1579 "5988957"
wdt:P2017 "CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C"
wdt:P2057 "HMDB0005034"
wdt:P2062 "7531"
wdt:P2067 339.099^^xsd:decimal
wdt:P2115 "N0000148493"
wdt:P2175 bipolar disorder
migraine
tonic–clonic seizure
migraine with aura
infantile epileptic encephalopathy
intracranial hypertension
mood disorder
post-traumatic stress disorder
epilepsy
essential tremor
focal epilepsy
pain
wdt:P2275 "topiramate"@en
wdt:P231 "97240-79-4"
wdt:P232 "619-263-3"
wdt:P233 "CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C"
wdt:P234 "InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1"
wdt:P235 "KJADKKWYZYXHBB-XBWDGYHZSA-N"
wdt:P244 "sh97000684"
wdt:P2566 "100.129.713"
wdt:P267 "N03AX11"
wdt:P274 "C₁₂H₂₁NO₈S"
wdt:P279 2,2,7,7-tetramethyltetrahydro-2H,3aH,7H-bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran-3a-yl)methyl sulfamate
wdt:P2840 "759251"
wdt:P2868 anti-obesity medication
carbonic anhydrase inhibitor
neuroprotective agent
anticonvulsant agent
developmental toxicant
wdt:P2877 "34631"
wdt:P2892 "C0076829"
"C0127173"
wdt:P3073 "90620"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID8023688"
wdt:P3345 "38404"
wdt:P3417 "Topiramate"
wdt:P3489 US pregnancy category D
Australian pregnancy category D
wdt:P3493 boxed warning
wdt:P3636 "TOR"
wdt:P366 medication
wdt:P373 "Topiramate"
wdt:P3780 Qudexy
Topamax
Trokendi
Topiragen
wdt:P4235 "topiramate"
wdt:P4250 0.3^^xsd:decimal
wdt:P4527 "510289"
wdt:P486 "D000077236"
wdt:P4964 "splash10-00di-0059000000-415c62c34b95b430780e"
"splash10-014i-0090000000-114dcddef02a03a7e050"
"splash10-01x0-1970000000-f0e80f5cc5d6fc2b6d38"
"splash10-03di-0239000000-994a7b97e101c455a792"
wdt:P592 "CHEMBL220492"
wdt:P595 "6849"
wdt:P6366 "2777683783"
wdt:P638 "3HKU"
"3LXE"
wdt:P646 "/m/01qb88"
wdt:P652 "0H73WJJ391"
wdt:P661 "4447672"
wdt:P662 "5284627"
wdt:P665 "D00537"
wdt:P6689 "MSBNK-Waters-WA001873"
"MSBNK-Waters-WA001874"
"MSBNK-Waters-WA001875"
"MSBNK-Waters-WA001876"
"MSBNK-Waters-WA001877"
wdt:P672 "D09.947.875.359.250.500"
"D09.947.875.465.354.500"
wdt:P683 "63631"
wdt:P715 "DB00273"
wdt:P7524 "topiramate"
wdt:P8189 "987007551783705171"
wdt:P8494 "DTXCID103688"
wdt:P9272 "57558"
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