SHMARQL

Alpha-2-macroglobulin

<http://www.wikidata.org/entity/Q22680187>

mammalian protein found in Homo sapiens
Alpha-2-macroglobulin
rdfs:label
"Alpha-2-macroglobulin"@en
skos:altLabel
"A2M"@en
"C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5"@en
"alpha-2-M"@en
"alpha-2-macroglobulin"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-07-20T10:42:13+00:00"^^xsd:dateTime
schema:version 2520146620
wikibase:identifiers 16
wikibase:sitelinks 12
wikibase:statements 74
p:P10283 wd:statement/Q22680187-2A5F897F-6893-484E-862D-84F512A5520C
p:P18 wd:statement/Q22680187-BD0C76E3-7B44-4977-BC9B-1051C8D7EC3C
p:P279 wd:statement/Q22680187-A7492CAF-3A14-4B8C-9AD6-451EE0645D7D
wd:statement/Q22680187-de504a60-48ee-ef88-97d2-17cf3026d807
p:P31 wd:statement/Q22680187-2BA6A1AC-281F-4964-A0DB-2D763843A6F3
p:P352 wd:statement/Q22680187-A6BD25CF-B858-499B-AE72-445C44137290
p:P361 wd:statement/Q22680187-170AF6FB-9B40-4502-B963-84F1D6415262
wd:statement/Q22680187-39667F74-95A4-463A-A59C-8FBA9F95DAAF
wd:statement/Q22680187-63E2D899-7609-4594-A655-287287CADD9F
wd:statement/Q22680187-7324A67F-5436-4E4F-84E6-63261CA052A6
wd:statement/Q22680187-7A908A2F-B705-4281-9CA9-193A0EA162E7
wd:statement/Q22680187-87C5F252-FFF4-44AC-BD79-840758543BA8
wd:statement/Q22680187-B7895648-6FFC-4778-B67A-57AED28C78C3
wd:statement/Q22680187-CA9091E2-AA80-4D61-8B39-B2A6E4BD2BE0
wd:statement/Q22680187-D27976F2-0D7F-4970-99AF-8DAB98C9CCFE
wd:statement/Q22680187-DD8EC5DA-94DF-4E84-B534-74439D902E9D
wd:statement/Q22680187-F217E2F7-0162-4870-93C3-034D4CAEA5A3
p:P527 wd:statement/Q22680187-03F00BE2-8A22-4642-8019-40AA63A1FC1B
wd:statement/Q22680187-0B3DD313-612B-4FA8-BC80-5797B8D6D675
wd:statement/Q22680187-18660134-B1A4-4A14-92FD-CFE8CAD5FBAC
wd:statement/Q22680187-241F6445-2FAD-4413-9400-86BF33D80B2A
wd:statement/Q22680187-452C26AE-B4B7-48D1-9B27-9902A1FBE355
wd:statement/Q22680187-5E8D6F12-3295-4CC8-B0F5-9C9FE21C6253
wd:statement/Q22680187-7C417D03-8438-4C84-826F-43E4F21AE047
p:P6366 wd:statement/Q22680187-89BBC1FE-BF10-4C60-B222-4E8958D294F5
p:P637 wd:statement/Q22680187-27CE4D3D-7E21-4043-85EF-126FC63AE7CA
wd:statement/Q22680187-6898BD62-6025-44FD-A3FF-461CBDA9CAA0
wd:statement/Q22680187-7FD1CED4-871F-466D-B04F-13E5B939A241
wd:statement/Q22680187-818955DF-C70B-4E8F-8958-226A34ADB82A
wd:statement/Q22680187-C03EB5DF-B433-4CE3-9BBA-F461CA0B262B
p:P638 wd:statement/Q22680187-274AA39F-C35B-4418-8E22-3C8CD27D2721
wd:statement/Q22680187-426EA3D0-AF0C-4AFC-A21C-F639B728ADCC
wd:statement/Q22680187-67FCC005-FBFE-49F5-A0F0-2BEEBCC5671F
p:P646 wd:statement/Q22680187-B9CFC819-710C-4DE1-81F3-A979B27F8377
p:P680 wd:statement/Q22680187-0DBB7AEE-D0AA-467A-BDC7-79B6AEED8782
wd:statement/Q22680187-12929B1F-0CBF-436F-8854-8FA0A36C6DA3
wd:statement/Q22680187-3DBE1575-DE9B-4617-8033-8BF91B75D93B
wd:statement/Q22680187-3E9B4C5F-5E9D-4E82-93A6-6C3FF0CC9F42
wd:statement/Q22680187-6597745C-E1E1-4ACD-8F23-49BB1FDEA9F7
wd:statement/Q22680187-745DAF8D-712D-4E46-9A12-9D5F3015FA0C
wd:statement/Q22680187-7D918183-69AE-43A0-ACD2-120C29FE9232
wd:statement/Q22680187-9ECA1C16-1EE9-49E0-AAC8-35D7CA4D78C6
wd:statement/Q22680187-A38D0F35-6F71-404F-9CF0-9980C4770CDA
wd:statement/Q22680187-B7B19817-2EFC-438B-BB54-6C9935E5AD17
wd:statement/Q22680187-BDEC3133-710D-4327-8684-6C64B2A5C6DD
wd:statement/Q22680187-BE6B17AF-C611-4C76-8FE3-0C769CC9ED35
wd:statement/Q22680187-D18F5823-DB38-4940-955C-326A999A96E1
wd:statement/Q22680187-E9A13E7A-41E5-4AAA-9DD1-52C6150C34B3
wd:statement/Q22680187-F21A87DC-7C0B-46CD-A48B-925A47A326B2
p:P681 wd:statement/Q22680187-1DCFFFF5-BE70-4547-A354-A8ABF202C067
wd:statement/Q22680187-202AB849-E015-45C2-BAFD-B42CB92BE552
wd:statement/Q22680187-3896699D-1CE9-4BD5-985E-1400D105F90B
wd:statement/Q22680187-44BC3763-7E2E-444E-BF87-B741AD1F99FF
wd:statement/Q22680187-62E4EC2A-F7D4-4C58-B9FE-1D0D63735194
wd:statement/Q22680187-841EF80A-BD8F-4C15-99DE-9DD0ECD7D3C2
wd:statement/Q22680187-943557E9-E0E5-442E-9688-4FC58ECA47AD
wd:statement/Q22680187-BC025293-2527-4DDD-BD63-84C449254E06
wd:statement/Q22680187-BC48521A-AD6A-4E98-8C74-A3C351F736AD
wd:statement/Q22680187-F44DEAB2-CF6A-41B8-AF1A-F49C991550C0
p:P682 wd:statement/Q22680187-07F4666E-0645-4786-99D7-A3BD514F6CED
wd:statement/Q22680187-18E5ED3B-CA06-4171-837D-D7255B1C2CAC
wd:statement/Q22680187-31D54122-E2D0-47C3-ABFB-17D03237FDAE
wd:statement/Q22680187-4AFBE227-BAB3-42AC-B3F6-9A486732A773
wd:statement/Q22680187-4F86FFDD-5A78-4ABC-83C8-7470CF4AE941
wd:statement/Q22680187-6D3AA66C-4794-4E7A-A2BA-7C25A4352F5C
wd:statement/Q22680187-9B2DD780-525F-4732-926B-0E7EF9416120
wd:statement/Q22680187-D16D3856-7082-404B-9C94-97A63E6DFECF
wd:statement/Q22680187-D35537B4-CB6D-49C2-A21A-78A4839A8477
p:P702 wd:statement/Q22680187-16387CEC-3FD2-4F76-8601-746B60A715C3
p:P703 wd:statement/Q22680187-655E74F3-22BA-4396-8BAC-4218D536CC36
p:P705 wd:statement/Q22680187-4FD2BB39-3D14-4F58-89A8-5FDE1EC93C95
wd:statement/Q22680187-DBAB08AB-2881-49D6-A5C9-D681A55F75AD
wd:statement/Q22680187-DFCA076D-45E9-48AE-B360-78381E8E1C03
wd:statement/Q22680187-F0521142-4621-49DC-BA56-F0D3EC3D1F19
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P01023>
p:direct-normalized/P6366 <https://makg.org/entity/52543561>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_000005>
<http://purl.uniprot.org/refseq/NP_001334352>
<http://purl.uniprot.org/refseq/NP_001334353>
<http://purl.uniprot.org/refseq/NP_001334354>
<http://purl.uniprot.org/refseq/XP_006719119>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1BV8>
<https://rdf.wwpdb.org/pdb/2P9R>
<https://rdf.wwpdb.org/pdb/4ACQ>
wdt:P10283 "C52543561"
wdt:P18 <http://commons.wikimedia.org/wiki/Special:FilePath/Crystal%20structure%20of%20alpha-2-macroglobulin.png>
wdt:P279 alpha globulin
protein
wdt:P31 protein
wdt:P352 "P01023"
wdt:P361 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
Immunoglobulin E-set
Immunoglobulin-like fold
Alpha-macroglobulin, receptor-binding domain superfamily
Alpha-macroglobulin, receptor-binding domain, protein family
Alpha-2-macroglobulin, protein family
Alpha-macroglobulin, TED domain, protein family
Alpha-2-macroglobulin, bait region domain, protein family
Macroglobulin domain, protein family
Alpha-2-macroglobulin, conserved site, protein family
TonB box, conserved site, protein family
wdt:P527 Alpha-macroglobulin, receptor-binding
TonB box, conserved site
Alpha-2-macroglobulin
Alpha-macroglobulin, TED domain
Alpha-2-macroglobulin, bait region domain
Alpha-2-macroglobulin, conserved site
Macroglobulin domain
wdt:P6366 "52543561"
wdt:P637 "NP_000005"
"NP_001334352"
"NP_001334353"
"NP_001334354"
"XP_006719119"
wdt:P638 "1BV8"
"2P9R"
"4ACQ"
wdt:P646 "/m/02kgmjl"
wdt:P680 enzyme binding
protease binding
signaling receptor binding
serine-type endopeptidase inhibitor activity
peptidase inhibitor activity
endopeptidase inhibitor activity
growth factor binding
calcium-dependent protein binding
GTPase activator activity
protein binding
interleukin-1 binding
interleukin-8 binding
tumor necrosis factor binding
wdt:P681 extracellular space
extracellular region
platelet alpha granule lumen
blood microparticle
cytosol
collagen-containing extracellular matrix
extracellular exosome
wdt:P682 platelet degranulation
blood coagulation, intrinsic pathway
negative regulation of endopeptidase activity
negative regulation of peptidase activity
stem cell differentiation
negative regulation of complement activation, lectin pathway
extracellular matrix disassembly
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
wdt:P702 A2M
wdt:P703 man
wdt:P705 "ENSP00000323929"
"ENSP00000385710"
"ENSP00000438599"
"ENSP00000445717"
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data from SPARQL profile: Wikidata