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rdfs:label
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"LYN"@fa
"LYN"@fr
"LYN"@uk
"LYN proto-oncogene, Src family tyrosine kinase"@en
"LYN proto-oncogene, Src family tyrosine kinase"@nl
"Tirozinska proteinska kinaza Lyn"@sh
"Tyrosinkinase Lyn"@de
"yn ennym lane ayds"@en-gb
"タンパク質チロシンキナーゼLyn"@ja
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skos:altLabel
|
"LYN"@en
|
|
"lck/Yes-related novel protein tyrosine kinase"@en
|
|
"p53Lyn"@en
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|
"p56Lyn"@en
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|
"tyrosine-protein kinase Lyn"@en
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|
"v-yes-1 Yamaguchi sarcoma viral related oncogene homolog"@en
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|
schema:description
|
"Protein"@de
"mammalian protein found in Homo sapiens"@en
"menselijk eiwit"@nl
"protein"@sv
"protein"@id
"proteinë"@sq
"protèin"@ace
"protéine humaine"@fr
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
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schema:dateModified
|
"2026-07-23T06:55:34+00:00"^^xsd:dateTime
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schema:version
|
2521520614
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wikibase:identifiers
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15
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wikibase:sitelinks
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6
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188
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wd:statement/Q2463389-FBA6F39D-A0F0-4F89-8CB9-9A3227A8E1F8
|
|
p:P702
|
wd:statement/Q2463389-FADBFD42-177C-4570-8820-CB9782A68A0A
|
|
p:P703
|
wd:statement/Q2463389-9E7F89EB-8FBE-4277-BF3B-DDE7DCB930B0
|
|
p:P705
|
wd:statement/Q2463389-04591C7C-043C-41F0-AAB7-CEF5AF08D830
|
|
wd:statement/Q2463389-8F9BED6D-6F80-467A-AFDB-D820E062401D
|
|
wd:statement/Q2463389-FFA2B639-ECDA-4194-A938-34087D74DD8A
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P07948>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/175818844>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001104567>
|
|
<http://purl.uniprot.org/refseq/NP_002341>
|
|
<http://purl.uniprot.org/refseq/XP_011515831>
|
|
<http://purl.uniprot.org/refseq/XP_016868904>
|
|
<http://purl.uniprot.org/refseq/XP_016868905>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1W1F>
|
|
<https://rdf.wwpdb.org/pdb/1WA7>
|
|
<https://rdf.wwpdb.org/pdb/3A4O>
|
|
wdt:P10283
|
"C175818844"
|
|
wdt:P129
|
SU6656
|
|
bafetinib
|
|
bosutinib
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P07948"
|
|
wdt:P361
|
Protein kinase-like domain superfamily
|
|
SH3-like domain superfamily
|
|
SH2 domain superfamily
|
|
Src family kinases (SFKs) [cytosol]
|
|
Tyrosine-protein kinase, catalytic domain, protein family
|
|
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
|
|
Protein kinase domain, protein family
|
|
SH3 domain, protein family
|
|
SH2 domain, protein family
|
|
Tyrosine-protein kinase Lyn, SH2 domain, protein family
|
|
Tyrosine-protein kinase Lyn, SH3 domain, protein family
|
|
Tyrosine-protein kinase, active site, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P527
|
tyrosine-protein kinase, catalytic domain
|
|
tyrosine-protein kinase, active site
|
|
serine-threonine/tyrosine-protein kinase, catalytic domain
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
SH3 domain
|
|
SH2 domain
|
|
Tyrosine-protein kinase Lyn, SH3 domain
|
|
Tyrosine-protein kinase Lyn, SH2 domain
|
|
wdt:P591
|
"2.7.10.2"
|
|
wdt:P6366
|
"175818844"
|
|
wdt:P637
|
"NP_001104567"
|
|
"NP_002341"
|
|
"XP_011515831"
|
|
"XP_016868904"
|
|
"XP_016868905"
|
|
wdt:P638
|
"1W1F"
|
|
"1WA7"
|
|
"3A4O"
|
|
wdt:P646
|
"/m/03cpykh"
|
|
wdt:P680
|
enzyme binding
|
|
integrin binding
|
|
ubiquitin protein ligase binding
|
|
ATP binding
|
|
signaling receptor binding
|
|
protein kinase activity
|
|
transferase activity
|
|
nucleotide binding
|
|
phosphoprotein binding
|
|
kinase activity
|
|
protein tyrosine kinase activity
|
|
glycosphingolipid binding
|
|
gamma-tubulin binding
|
|
SH3 domain binding
|
|
non-membrane spanning protein tyrosine kinase activity
|
|
platelet-derived growth factor receptor binding
|
|
ephrin receptor binding
|
|
transmembrane transporter binding
|
|
protein binding
|
|
protein-containing complex binding
|
|
phosphorylation-dependent protein binding
|
|
wdt:P681
|
mitochondrial crista
|
|
perinuclear region of cytoplasm
|
|
membrane
|
|
intracellular membrane-bounded organelle
|
|
mitochondrial intermembrane space
|
|
mast cell granule
|
|
mitochondrial membranes
|
|
extrinsic component of cytoplasmic side of plasma membrane
|
|
integrin alpha2-beta1 complex
|
|
cytosol
|
|
glutamatergic synapse
|
|
postsynaptic specialization, intracellular component
|
|
plasma membrane
|
|
nucleus
|
|
membrane raft
|
|
postsynaptic density
|
|
cytoplasm
|
|
Golgi apparatus
|
|
extracellular exosome
|
|
wdt:P682
|
response to toxic substance
|
|
central nervous system development
|
|
positive regulation of neuron projection development
|
|
positive regulation of phosphatidylinositol 3-kinase signaling
|
|
peptidyl-tyrosine phosphorylation
|
|
positive regulation of peptidyl-tyrosine phosphorylation
|
|
negative regulation of cell population proliferation
|
|
response to hormone
|
|
response to insulin
|
|
positive regulation of cell population proliferation
|
|
positive regulation of cell migration
|
|
positive regulation of phosphatidylinositol 3-kinase activity
|
|
cellular response to DNA damage stimulus
|
|
platelet degranulation
|
|
platelet activation
|
|
leukocyte migration
|
|
positive regulation of protein phosphorylation
|
|
inflammatory response
|
|
growth hormone receptor signaling pathway via JAK-STAT
|
|
response to peptide hormone
|
|
response to organic cyclic compound
|
|
cellular response to retinoic acid
|
|
regulation of protein phosphorylation
|
|
intracellular signal transduction
|
|
positive regulation of Ras protein signal transduction
|
|
response to axon injury
|
|
erythrocyte differentiation
|
|
oligodendrocyte development
|
|
positive regulation of oligodendrocyte progenitor proliferation
|
|
regulation of inflammatory response
|
|
positive regulation of phosphorylation
|
|
response to amino acid
|
|
negative regulation of protein phosphorylation
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
|
B cell homeostasis
|
|
B cell receptor signaling pathway
|
|
negative regulation of ERK1 and ERK2 cascade
|
|
Fc-gamma receptor signaling pathway involved in phagocytosis
|
|
negative regulation of MAP kinase activity
|
|
neuron projection development
|
|
negative regulation of B cell proliferation
|
|
positive regulation of glial cell proliferation
|
|
viral process
|
|
T cell costimulation
|
|
dendritic cell differentiation
|
|
tolerance induction to self antigen
|
|
negative regulation of immune response
|
|
Fc-epsilon receptor signaling pathway
|
|
regulation of cytokine production
|
|
regulation of ERK1 and ERK2 cascade
|
|
cellular response to heat
|
|
regulation of B cell apoptotic process
|
|
lipopolysaccharide-mediated signaling pathway
|
|
adaptive immune response
|
|
response to carbohydrate
|
|
cellular response to extracellular stimulus
|
|
regulation of cell adhesion mediated by integrin
|
|
ephrin receptor signaling pathway
|
|
histamine secretion by mast cell
|
|
positive regulation of tyrosine phosphorylation of STAT protein
|
|
regulation of platelet aggregation
|
|
regulation of erythrocyte differentiation
|
|
immune response-regulating cell surface receptor signaling pathway
|
|
positive regulation of mast cell proliferation
|
|
negative regulation of toll-like receptor 2 signaling pathway
|
|
positive regulation of dendritic cell apoptotic process
|
|
immune system process
|
|
regulation of mast cell degranulation
|
|
negative regulation of toll-like receptor 4 signaling pathway
|
|
peptidyl-tyrosine autophosphorylation
|
|
Fc receptor mediated stimulatory signaling pathway
|
|
negative regulation of myeloid leukocyte differentiation
|
|
Fc receptor mediated inhibitory signaling pathway
|
|
response to sterol depletion
|
|
regulation of mast cell activation
|
|
regulation of B cell receptor signaling pathway
|
|
regulation of release of sequestered calcium ion into cytosol
|
|
positive regulation of Fc receptor mediated stimulatory signaling pathway
|
|
positive regulation of stress-activated protein kinase signaling cascade
|
|
negative regulation of mast cell proliferation
|
|
regulation of monocyte chemotaxis
|
|
positive regulation of B cell receptor signaling pathway
|
|
blood coagulation
|
|
cell differentiation
|
|
stimulatory C-type lectin receptor signaling pathway
|
|
negative regulation of intracellular signal transduction
|
|
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
|
|
phosphorylation
|
|
protein autophosphorylation
|
|
innate immune response
|
|
protein phosphorylation
|
|
signal transduction
|
|
hemopoiesis
|
|
wdt:P702
|
LYN
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000428313"
|
|
"ENSP00000428424"
|
|
"ENSP00000428924"
|