angiotensinogen

mammalian protein found in Homo sapiens
rdfs:label
"angiotensinogen"@en
skos:altLabel
"AGT"@en
"alpha-1 antiproteinase"@en
"alpha-1 antiproteinase, antitrypsin"@en
"antitrypsin"@en
"fetal-liver predominant transporter 1"@en
"pre-angiotensinogen"@en
"serine (or cysteine) proteinase inhibitor"@en
"serpin A8"@en
"serpin peptidase inhibitor, clade A, member 8"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-07-15T01:38:41+00:00"^^xsd:dateTime
schema:version 2517586668
wikibase:identifiers 11
wikibase:sitelinks 14
wikibase:statements 101
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p:P2868 wd:statement/Q267200-5630825E-05B3-4C9F-8814-E114D38EE026
p:P2888 wd:statement/Q267200-217445E7-E3B5-47BA-975A-040EA6AA80FB
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p:P361 wd:statement/Q267200-43B06615-33A7-4E43-BC42-D823B18893B4
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p:P3937 wd:statement/Q267200-e7ec6e7b-4d98-b0ae-49c2-6c6c308dba2f
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wd:statement/Q267200-DB0FDF73-7BC0-4FD5-BF36-8D24E1DA76F5
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wd:statement/Q267200-E5D36FB5-FE6E-41E0-810C-A29B2B6D6AC9
wd:statement/Q267200-EB459DFD-D179-46BE-A5AA-3E57C8A2912D
wd:statement/Q267200-F36B05EA-04C1-425F-B004-366EB87CA616
wd:statement/Q267200-F9179A26-E8EE-46A3-9AC9-FE9D4EB972EA
p:P683 wd:statement/Q267200-3174af93-4e7d-6543-3417-c14b05601e0c
p:P692 wd:statement/Q267200-284DBEC7-AD5D-4BA6-9BC3-AAAB7F7CB53D
p:P702 wd:statement/Q267200-D48E32FC-E9BE-43AA-93E8-8563DCDE453D
p:P703 wd:statement/Q267200-74F6671B-540C-4243-92EC-C5A62D7C6495
p:P705 wd:statement/Q267200-78F1A773-5CB4-4BAB-BD35-C69B1338E097
p:direct-normalized/P2671 <http://g.co/kg/g/121dvjvc>
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P01019>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_000020>
<http://purl.uniprot.org/refseq/NP_001369746>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/2WXW>
<https://rdf.wwpdb.org/pdb/2X0B>
<https://rdf.wwpdb.org/pdb/4APH>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_2720>
wdt:P1417 "science/angiotensinogen"
wdt:P2671 "/g/121dvjvc"
wdt:P2868 serine proteinase inhibitor
wdt:P2888 <http://purl.uniprot.org/uniprot/P01019>
wdt:P31 protein precursor
protein
wdt:P352 "P01019"
wdt:P361 angiotensinogen
Serpin superfamily
Metabolism of Angiotensinogen to Angiotensins
Serpin domain, protein family
Angiotensinogen serpin domain, protein family
Serpin, conserved site, protein family
wdt:P373 "Angiotensinogen"
wdt:P3937 "R-HSA-1998759"
wdt:P527 Serpin, conserved site
Serpin domain
Angiotensinogen serpin domain
angiotensins
wdt:P637 "NP_000020"
"NP_001369746"
wdt:P638 "2WXW"
"2X0B"
"4APH"
wdt:P680 serine-type endopeptidase inhibitor activity
protein binding
wdt:P681 extracellular space
extracellular region
blood microparticle
cytosol
collagen-containing extracellular matrix
cytoplasm
extracellular exosome
wdt:P682 vasoconstriction
associative learning
positive regulation of neuron projection development
negative regulation of cell growth
positive regulation of cell population proliferation
response to estradiol
regulation of apoptotic process
cell-cell signaling
positive regulation of nitric oxide biosynthetic process
positive regulation of insulin receptor signaling pathway
positive regulation of cardiac muscle cell apoptotic process
female pregnancy
cell surface receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
ERK1 and ERK2 cascade
regulation of heart rate
positive regulation of renal sodium excretion
positive regulation of blood pressure
angiotensin maturation
negative regulation of angiogenesis
angiotensin-mediated drinking behavior
positive regulation of extracellular matrix constituent secretion
cellular sodium ion homeostasis
activation of phospholipase C activity
positive regulation of cardiac muscle hypertrophy
negative regulation of endopeptidase activity
regulation of norepinephrine secretion
artery smooth muscle contraction
response to muscle activity involved in regulation of muscle adaptation
positive regulation of superoxide anion generation
negative regulation of tissue remodeling
vasodilation
fibroblast proliferation
positive regulation of fibroblast proliferation
regulation of long-term neuronal synaptic plasticity
smooth muscle cell proliferation
negative regulation of neurotrophin TRK receptor signaling pathway
stress-activated MAPK cascade
regulation of calcium ion transport
cell growth involved in cardiac muscle cell development
cellular response to mechanical stimulus
renal system process
positive regulation of catalytic activity
regulation of systemic arterial blood pressure by renin-angiotensin
regulation of signaling receptor activity
protein import into nucleus
regulation of lipid metabolic process
regulation of transmission of nerve impulse
uterine smooth muscle contraction
regulation of molecular function
cellular response to angiotensin
positive regulation of vascular associated smooth muscle cell migration
positive regulation of vascular associated smooth muscle cell proliferation
positive regulation of L-lysine import across plasma membrane
positive regulation of L-arginine import across plasma membrane
ageing
operant conditioning
wdt:P683 "2720"
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20AGT%20202834%20at%20fs.png>
wdt:P702 AGT
wdt:P703 man
wdt:P705 "ENSP00000355627"
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