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rdfs:label
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"Cicavčí cieľ rapamycínu"@sk
"Kinaza mTOR"@pl
"MTOR"@cs
"MTOR"@de
"MTOR"@pt
"MTOR"@bs
"MTOR"@cy
"MTOR"@fa
"MTOR"@id
"MTOR"@it
"MTOR"@ja
"MTOR"@ru
"MTOR"@uk
"MTORC"@sv
"TOR"@he
"diana de rapamicina en células de mamífero"@es
"mTOR"@fr
"mTOR"@ca
"mechanistic target of rapamycin kinase"@en
"هدف الثدييات من الراباميسين"@ar
"雷帕黴素的機理靶標"@zh
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skos:altLabel
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"Diana de rapamicina en celulas de mamifero"@es
"FK506 binding protein 12-rapamycin associated protein 2"@en
"FK506-binding protein 12-rapamycin complex-associated protein 1"@en
"FKBP-rapamycin associated protein"@en
"FKBP12-rapamycin complex-associated protein"@en
"FKBP12-rapamycin complex-associated protein 1"@en
"FRAP"@pl
"MTOR"@en
"MTOR"@pl
"Mammalian Target of Rapamycin"@de
"Mechanistic target of rapamycin"@en
"mammalian target of rapamycin"@en
"mammalian target of rapamycin"@cs
"mechanistic target of rapamycin"@cs
"mechanistic target of rapamycin (serine/threonine kinase)"@en
"rapamycin and FKBP12 target 1"@en
"rapamycin associated protein FRAP2"@en
"rapamycin target protein 1"@en
"serine/threonine-protein kinase mTOR"@en
"哺乳類ラパマイシン標的タンパク質"@ja
"機械的ラパマイシン標的タンパク質"@ja
"機構的ラパマイシン標的タンパク質"@ja
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schema:description
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"Protein"@de
"enzima"@it
"enzym - kináza"@cs
"enzyme"@fr
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteína presente en las células de mamíferos"@es
"proteïne in Mechanistic target of rapamycin kinase"@nl
"protèin"@ace
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
"بروتين في الإنسان العاقل"@ary
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schema:dateModified
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"2026-07-23T06:50:28+00:00"^^xsd:dateTime
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schema:version
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2521519526
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wikibase:identifiers
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36
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21
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wd:statement/Q285613-7E15565C-F83B-4470-9AC8-EBA12F1249AA
|
|
wd:statement/Q285613-8061B389-4838-4A12-B660-8C8FFF2CA833
|
|
wd:statement/Q285613-81C285E2-6CAC-42FB-9377-4D8C78FFCF37
|
|
wd:statement/Q285613-82398D07-8FF9-450D-8568-0CD8334E1C34
|
|
wd:statement/Q285613-8518C886-D7CE-45B5-AEC3-C6785542C875
|
|
wd:statement/Q285613-896DB9A9-9B26-45AC-8879-C497C55AB0F5
|
|
wd:statement/Q285613-8BE6A787-2620-4C1D-BF3B-88EC7A933F48
|
|
wd:statement/Q285613-8CE5453A-3257-4EC2-AFB0-1334C1033120
|
|
wd:statement/Q285613-8EF8F874-68E9-4DB4-8282-BABF3994A2DA
|
|
wd:statement/Q285613-8F3C4970-B7FA-4F58-BD8A-CC1037156B7C
|
|
wd:statement/Q285613-902D89CE-8718-4397-972F-635E97448E3A
|
|
wd:statement/Q285613-928370A0-EFAA-4794-AB69-79F83DA28651
|
|
wd:statement/Q285613-9337475B-1932-4B17-B815-59566B5DD051
|
|
wd:statement/Q285613-94C609CE-94F2-44B6-B5D0-8C24913DC304
|
|
wd:statement/Q285613-955DF0C6-D5BA-403C-88D2-1FCD78815C2C
|
|
wd:statement/Q285613-969DAA9D-EF06-4ACD-A4F9-8EC5EF23C94A
|
|
wd:statement/Q285613-9C82DEA6-079F-437B-BD12-6DE1FFE1DB5E
|
|
wd:statement/Q285613-A387A0BE-DD83-4D13-9E86-E2A05F069072
|
|
wd:statement/Q285613-A444938E-2D4E-4217-9B5C-BC2AE62953D0
|
|
wd:statement/Q285613-A5D3EFCD-3EB0-447D-A5E5-96D5144103A0
|
|
wd:statement/Q285613-A8B935DB-982A-428F-B525-B8C77FF07A56
|
|
wd:statement/Q285613-AA02B5CE-03B9-4EBF-A5DC-412F274A9C47
|
|
wd:statement/Q285613-AB706EDF-790E-4FC2-A984-D61184E341F5
|
|
wd:statement/Q285613-ACCF9B38-E21A-475D-B19E-93519C6D93D2
|
|
wd:statement/Q285613-ADC16BD6-EC04-45A4-8222-547815040CF8
|
|
wd:statement/Q285613-AF9D5A5F-9BB3-46DA-BCB3-591D7A5EDB15
|
|
wd:statement/Q285613-B0961651-3B80-4654-9F01-9D1D1FAF1EA3
|
|
wd:statement/Q285613-B20457A2-F47A-4BFC-AD92-9C0B3904D6A7
|
|
wd:statement/Q285613-B7C75538-5BED-42DB-AF89-5ABF988E6255
|
|
wd:statement/Q285613-B8DB0C59-8317-4CA6-A3ED-1A471E05477A
|
|
wd:statement/Q285613-BB7D59D4-AB7C-4605-8388-811AF693E852
|
|
wd:statement/Q285613-BCC05A33-C799-4F7E-9DF4-C1688538D942
|
|
wd:statement/Q285613-BD74E8CE-FC08-42BF-8D40-9B8AD4C26769
|
|
wd:statement/Q285613-BD96FB47-7AA6-4E59-8A51-2782987C17D7
|
|
wd:statement/Q285613-BE3B5FD2-DA73-4831-BE55-A85508BCE2A1
|
|
wd:statement/Q285613-BF5FFC83-3C88-4546-99EC-1133D41508D0
|
|
wd:statement/Q285613-C06CB719-4EBC-4524-BC83-10C704F4DCEE
|
|
wd:statement/Q285613-C169BA24-5704-4971-9B6B-BA39D912573B
|
|
wd:statement/Q285613-C2FC5F9A-C2FF-4BC5-BCD6-F9958A098A3F
|
|
wd:statement/Q285613-C31E4C2E-84F2-4B50-A2BF-ADD7C175CAD0
|
|
wd:statement/Q285613-C59E72A6-188C-4D64-A29E-A65067BE52D1
|
|
wd:statement/Q285613-C608C1DD-3C1B-4B21-9765-045218477EDF
|
|
wd:statement/Q285613-C8F0BE66-A10D-444F-840A-E94B4D6E4D5D
|
|
wd:statement/Q285613-D3CC635B-809B-4D4E-9775-87C6C780DEC7
|
|
wd:statement/Q285613-D45DACFC-2094-45CD-9017-2BD6B8FA8F1D
|
|
wd:statement/Q285613-E099B70F-A839-415A-81CC-3905418EAAA6
|
|
wd:statement/Q285613-E14550CA-11CE-42BF-AF7B-1CC05B5FFC81
|
|
wd:statement/Q285613-E575F552-F581-4B3B-9FEC-DB630F34CD69
|
|
wd:statement/Q285613-E60589D7-95FF-42A6-8366-63811DAB5A95
|
|
wd:statement/Q285613-E7815354-5FED-47E4-BFC9-D76AE6B5EB32
|
|
wd:statement/Q285613-E9D7F2F2-ED07-4271-98FC-131014380E8E
|
|
wd:statement/Q285613-ECCDA008-AAFB-4647-A565-B0FBD04917A4
|
|
wd:statement/Q285613-F20C1DBA-B869-446A-ADB3-923C795BAD07
|
|
wd:statement/Q285613-F59D0D1C-F30B-4692-BA0D-84F2D366360B
|
|
wd:statement/Q285613-F6CBFE20-0185-444F-94A7-AE1A80556142
|
|
wd:statement/Q285613-F8D6788F-5DA1-45DE-9511-8CE970A45C9E
|
|
wd:statement/Q285613-F9500831-8DD0-427D-8627-FF0391401AB2
|
|
wd:statement/Q285613-FC307C28-3B3E-4DE3-A2CA-8CE6C259EDA4
|
|
wd:statement/Q285613-FD6BC045-E728-45FE-8864-49DAAA13EA92
|
|
wd:statement/Q285613-FE7D0725-48F4-418B-AC4C-850A41BC597E
|
|
p:P692
|
wd:statement/Q285613-CF8B73C0-0CB0-41AA-8066-1B83BDF1CFF3
|
|
p:P702
|
wd:statement/q285613-64E05E39-75D0-4698-830C-6EBC75055201
|
|
p:P703
|
wd:statement/Q285613-B27B9DC5-1344-4A2A-AFFB-1B4E2875D946
|
|
p:P705
|
wd:statement/Q285613-582EB857-4B35-4A72-AAB0-F836AEDD7555
|
|
wd:statement/Q285613-AC10B77C-EB25-497C-94F7-512A77E820F7
|
|
wd:statement/q285613-0C830FCD-F1C6-4E2C-95A0-6CC149802791
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P42345>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/2777949483>
|
|
<https://makg.org/entity/2910776440>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_004949>
|
|
<http://purl.uniprot.org/refseq/XP_005263495>
|
|
<http://purl.uniprot.org/refseq/XP_011539468>
|
|
<http://purl.uniprot.org/refseq/XP_016856389>
|
|
<http://purl.uniprot.org/refseq/XP_016856390>
|
|
<http://purl.uniprot.org/refseq/XP_016856391>
|
|
<http://purl.uniprot.org/refseq/XP_024301955>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1AUE>
|
|
<https://rdf.wwpdb.org/pdb/1FAP>
|
|
<https://rdf.wwpdb.org/pdb/1NSG>
|
|
<https://rdf.wwpdb.org/pdb/2FAP>
|
|
<https://rdf.wwpdb.org/pdb/2GAQ>
|
|
<https://rdf.wwpdb.org/pdb/2NPU>
|
|
<https://rdf.wwpdb.org/pdb/2RSE>
|
|
<https://rdf.wwpdb.org/pdb/3FAP>
|
|
<https://rdf.wwpdb.org/pdb/4DRH>
|
|
<https://rdf.wwpdb.org/pdb/4DRI>
|
|
<https://rdf.wwpdb.org/pdb/4DRJ>
|
|
<https://rdf.wwpdb.org/pdb/4FAP>
|
|
<https://rdf.wwpdb.org/pdb/4JSN>
|
|
<https://rdf.wwpdb.org/pdb/4JSP>
|
|
<https://rdf.wwpdb.org/pdb/4JSV>
|
|
<https://rdf.wwpdb.org/pdb/4JSX>
|
|
<https://rdf.wwpdb.org/pdb/4JT5>
|
|
<https://rdf.wwpdb.org/pdb/4JT6>
|
|
<https://rdf.wwpdb.org/pdb/5FLC>
|
|
wdt:P10283
|
"C2777949483"
|
|
"C2909523446"
|
|
"C86554907"
|
|
wdt:P129
|
perhexiline
|
|
ridaforolimus
|
|
apitolisib
|
|
azd-8055
|
|
indoximod
|
|
sapanisertib
|
|
omipalisib
|
|
vistusertib
|
|
everolimus
|
|
dactolisib
|
|
temsirolimus
|
|
wdt:P2888
|
<http://purl.uniprot.org/uniprot/P42345>
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P42345"
|
|
wdt:P361
|
serine/threonine-protein kinase TOR
|
|
Tetratricopeptide-like helical domain superfamily
|
|
Protein kinase-like domain superfamily
|
|
Armadillo-like helical
|
|
Armadillo-type fold
|
|
FKBP12-rapamycin binding domain superfamily
|
|
Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
|
|
FKBP12-rapamycin binding domain, protein family
|
|
PIK-related kinase family
|
|
Domain of unknown function DUF3385, target of rapamycin protein family
|
|
Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family
|
|
FATC domain, protein family
|
|
PIK-related kinase, FAT family
|
|
Phosphatidylinositol 3/4-kinase, conserved site, protein family
|
|
wdt:P373
|
"TOR serine-threonine kinases"
|
|
wdt:P527
|
FKBP12-rapamycin binding domain
|
|
PIK-related kinase
|
|
Domain of unknown function DUF3385, target of rapamycin protein
|
|
Phosphatidylinositol 3-/4-kinase, catalytic domain
|
|
Phosphatidylinositol 3/4-kinase, conserved site
|
|
FATC domain
|
|
PIK-related kinase, FAT
|
|
wdt:P591
|
"2.7.10.2"
|
|
"2.7.11.1"
|
|
wdt:P6366
|
"2777949483"
|
|
"2910776440"
|
|
wdt:P637
|
"NP_004949"
|
|
"XP_005263495"
|
|
"XP_011539468"
|
|
"XP_016856389"
|
|
"XP_016856390"
|
|
"XP_016856391"
|
|
"XP_024301955"
|
|
wdt:P638
|
"1AUE"
|
|
"1FAP"
|
|
"1NSG"
|
|
"2FAP"
|
|
"2GAQ"
|
|
"2NPU"
|
|
"2RSE"
|
|
"3FAP"
|
|
"4DRH"
|
|
"4DRI"
|
|
"4DRJ"
|
|
"4FAP"
|
|
"4JSN"
|
|
"4JSP"
|
|
"4JSV"
|
|
"4JSX"
|
|
"4JT5"
|
|
"4JT6"
|
|
"5FLC"
|
|
wdt:P646
|
"/m/0860kt"
|
|
wdt:P680
|
protein serine/threonine kinase activity
|
|
identical protein binding
|
|
ATP binding
|
|
protein kinase binding
|
|
protein kinase activity
|
|
transferase activity
|
|
nucleotide binding
|
|
protein domain specific binding
|
|
phosphoprotein binding
|
|
kinase activity
|
|
TFIIIC-class transcription factor complex binding
|
|
ribosome binding
|
|
translation regulator activity
|
|
protein binding
|
|
protein-containing complex binding
|
|
wdt:P681
|
dendrite
|
|
endoplasmic reticulum membrane
|
|
mitochondrial outer membrane
|
|
membrane
|
|
intracellular membrane-bounded organelle
|
|
Golgi membrane
|
|
soma
|
|
nucleoplasm
|
|
PML body
|
|
phosphatidylinositol 3-kinase complex
|
|
TORC1 complex
|
|
TORC2 complex
|
|
organelle membrane
|
|
lysosomal membrane
|
|
cytosol
|
|
protein-containing complex
|
|
postsynaptic cytosol
|
|
glutamatergic synapse
|
|
mitochondrion
|
|
nucleus
|
|
cytoplasm
|
|
endoplasmic reticulum
|
|
Golgi apparatus
|
|
lysosome
|
|
endomembrane system
|
|
wdt:P682
|
growth
|
|
brain development
|
|
positive regulation of neuron projection development
|
|
positive regulation of peptidyl-tyrosine phosphorylation
|
|
response to insulin
|
|
positive regulation of gene expression
|
|
energy reserve metabolic process
|
|
activation of protein kinase B activity
|
|
positive regulation of nitric oxide biosynthetic process
|
|
positive regulation of lipid biosynthetic process
|
|
positive regulation of protein kinase B signaling
|
|
multicellular organism growth
|
|
cellular response to hypoxia
|
|
positive regulation of protein phosphorylation
|
|
positive regulation of cell death
|
|
response to activity
|
|
response to cocaine
|
|
regulation of protein phosphorylation
|
|
peptidyl-serine phosphorylation
|
|
heart morphogenesis
|
|
regulation of cell growth
|
|
'de novo' pyrimidine nucleobase biosynthetic process
|
|
positive regulation of oligodendrocyte differentiation
|
|
regulation of myelination
|
|
response to nutrient
|
|
response to amino acid
|
|
negative regulation of protein phosphorylation
|
|
positive regulation of actin filament polymerization
|
|
negative regulation of autophagy
|
|
positive regulation of neuron maturation
|
|
peptidyl-threonine phosphorylation
|
|
positive regulation of smooth muscle cell proliferation
|
|
positive regulation of neurogenesis
|
|
regulation of response to food
|
|
positive regulation of translation
|
|
cardiac muscle contraction
|
|
cellular response to starvation
|
|
positive regulation of dendritic spine development
|
|
response to morphine
|
|
response to nutrient levels
|
|
positive regulation of glial cell proliferation
|
|
positive regulation of stress fiber assembly
|
|
ruffle organization
|
|
positive regulation of endothelial cell proliferation
|
|
regulation of protein kinase activity
|
|
T-helper 1 cell lineage commitment
|
|
positive regulation of transcription by RNA polymerase III
|
|
cardiac muscle tissue development
|
|
germ cell development
|
|
regulation of glycogen biosynthetic process
|
|
positive regulation of lamellipodium assembly
|
|
positive regulation of myotube differentiation
|
|
negative regulation of macroautophagy
|
|
protein catabolic process
|
|
cellular response to nutrient levels
|
|
TOR signaling
|
|
regulation of fatty acid beta-oxidation
|
|
regulation of actin cytoskeleton organization
|
|
regulation of carbohydrate utilization
|
|
negative regulation of cell size
|
|
regulation of carbohydrate metabolic process
|
|
cell projection organization
|
|
maternal process involved in female pregnancy
|
|
negative regulation of calcineurin-NFAT signaling cascade
|
|
positive regulation of epithelial to mesenchymal transition
|
|
cellular response to amino acid stimulus
|
|
regulation of osteoclast differentiation
|
|
regulation of protein kinase B signaling
|
|
cardiac muscle cell development
|
|
spinal cord development
|
|
negative regulation of protein ubiquitination
|
|
regulation of GTPase activity
|
|
positive regulation of neuron death
|
|
positive regulation of phosphoprotein phosphatase activity
|
|
positive regulation of keratinocyte migration
|
|
mRNA stabilization
|
|
positive regulation of cell growth involved in cardiac muscle cell development
|
|
wound healing
|
|
long-term memory
|
|
DNA repair
|
|
regulation of cellular response to heat
|
|
positive regulation of wound healing, spreading of epidermal cells
|
|
cardiac cell development
|
|
voluntary musculoskeletal movement
|
|
cellular response to amino acid starvation
|
|
regulation of brown fat cell differentiation
|
|
regulation of cell size
|
|
regulation of membrane permeability
|
|
regulation of macroautophagy
|
|
heart valve morphogenesis
|
|
positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
|
|
negative regulation of muscle atrophy
|
|
cellular response to leucine
|
|
cellular response to leucine starvation
|
|
positive regulation of cytoplasmic translational initiation
|
|
regulation of translation at synapse, modulating synaptic transmission
|
|
positive regulation of sensory perception of pain
|
|
positive regulation of skeletal muscle hypertrophy
|
|
negative regulation of iodide transmembrane transport
|
|
TORC1 signaling
|
|
negative regulation of cholangiocyte apoptotic process
|
|
positive regulation of eating behavior
|
|
positive regulation of granulosa cell proliferation
|
|
positive regulation of cholangiocyte proliferation
|
|
phosphorylation
|
|
protein autophosphorylation
|
|
post-embryonic development
|
|
anoikis
|
|
protein phosphorylation
|
|
visual learning
|
|
signal transduction
|
|
social behavior
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20FRAP1%20202288%20at%20fs.png>
|
|
wdt:P702
|
MTOR
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000354558"
|
|
"ENSP00000366034"
|
|
"ENSP00000398745"
|
