Adenosine deaminase

mammalian protein found in Homo sapiens
rdfs:label
"Adenosine deaminase"@en
skos:altLabel
"ADA"@en
"adenosine aminohydrolase"@en
"adenosine deaminase"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-07-23T06:50:37+00:00"^^xsd:dateTime
schema:version 2521519557
wikibase:identifiers 17
wikibase:sitelinks 19
wikibase:statements 109
p:P10283 wd:statement/Q356093-35957336-278C-4C47-9DFC-9EB3CBEF4200
wd:statement/Q356093-8A347139-625D-4596-8226-F01ADAA1CD41
p:P10376 wd:statement/Q356093-4776A95B-1F41-4F07-B6D1-6EA875EFB5DB
p:P129 wd:statement/Q356093-4E2E4503-4DD4-4F3A-95A0-4FEB23AC062D
wd:statement/Q356093-836239F2-6054-4C74-8B8C-0B7779495BB2
p:P18 wd:statement/Q356093-473B8D2E-AF27-4735-9632-DEE80F5325B2
p:P2888 wd:statement/Q356093-10FCC74B-4B64-4206-8AD1-9F3D24E6A96E
p:P31 wd:statement/Q356093-4EA3C2BA-0CA3-4E0B-AAFA-96C282426AA9
p:P349 wd:statement/Q356093-50420393-C9C6-423C-BB64-7B584F8197AF
p:P352 wd:statement/q356093-9069EDA1-83ED-4A53-A870-77F5F10D7B8F
p:P361 wd:statement/Q356093-0B05119C-3398-46C5-AE1A-7C3BAB4F59CC
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p:P591 wd:statement/Q356093-EDB0ACEB-8875-4271-82A5-0A4318BCC570
p:P6366 wd:statement/Q356093-2C2EA681-3874-417E-BC3A-2F4B57660947
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p:P637 wd:statement/Q356093-1EE0EEA6-0096-4DE2-802B-A058BD697E00
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p:P646 wd:statement/Q356093-B08EBF61-2464-4882-8F47-99AB32600C95
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p:P682 wd:statement/Q356093-02BB5D16-CEA6-4F25-A877-31039D67CC1E
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wd:statement/Q356093-03E848E4-2E8A-4668-A19F-90C015C07143
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wd:statement/Q356093-059A5170-E1B3-4599-AB3E-9BE0D7B4CBAD
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wd:statement/Q356093-1212A12B-F16B-4E1E-9322-FAAFABDC4F97
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wd:statement/Q356093-31A6A966-0C43-493A-BA54-D7FEB5AB0F06
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wd:statement/Q356093-3B43F8B1-3D80-498E-8C19-1B3FFFBE15B3
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wd:statement/Q356093-7C95C824-78E1-44ED-9A4E-0584C97251C3
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wd:statement/Q356093-8C5027DC-A606-4621-9D10-C06486B886BD
wd:statement/Q356093-995C589A-3895-4572-9CF3-8C5AEE012737
wd:statement/Q356093-9B536CF7-37B4-4531-850E-AA330E353DA1
wd:statement/Q356093-9C2C0FB8-F6AC-4085-AABF-68457EAD09DB
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wd:statement/Q356093-B2CDEA87-EF54-43C3-A808-A14A534B2606
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wd:statement/Q356093-C94F8EFE-45AD-4102-B2E3-76499EC81269
wd:statement/Q356093-CA1FB4D1-F453-4BC8-BC7C-E66BBFF6829C
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wd:statement/Q356093-D9237E4F-AF60-4D44-862F-D317F700A6A6
wd:statement/Q356093-E0C898D9-7871-49D5-B652-4DDB3AC49DAD
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wd:statement/Q356093-E461E80A-B6FB-48CB-B4A2-70CA31041DEC
wd:statement/Q356093-E4A54859-80DF-43DD-BC29-0674E3EBE431
wd:statement/Q356093-EF343B34-12A1-4A86-B072-EC4DFBBD7A94
wd:statement/Q356093-FE14B52A-561C-47C6-BE9F-3358FD7260B7
p:P692 wd:statement/Q356093-4AD32B62-D7C6-4E17-A790-5AD0269CCF6E
p:P702 wd:statement/q356093-79AB7898-AE88-4C43-A00E-DE0B142A5851
p:P703 wd:statement/Q356093-5FE2EBE1-2D45-487B-99DB-CB174FFB1F46
p:P705 wd:statement/Q356093-6A111138-BF98-40EC-804C-2C607DBD1AE8
wd:statement/Q356093-A26EC58D-1FB6-4047-9309-BD18104E86A9
wd:statement/Q356093-B1AA24D0-5030-4D81-AF5F-BA3E6E8373FC
wd:statement/q356093-EF94EEB4-0519-4E49-B499-0E67777B2830
p:P8814 wd:statement/Q356093-FA1C7B6D-4D83-46A2-A39B-94F0993BBBF7
p:direct-normalized/P349 <http://id.ndl.go.jp/auth/ndlna/00575923>
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P00813>
p:direct-normalized/P6366 <https://makg.org/entity/2909476619>
<https://makg.org/entity/34628245>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_000013>
<http://purl.uniprot.org/refseq/NP_001308979>
<http://purl.uniprot.org/refseq/NP_001308980>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/3IAR>
p:direct-normalized/P8814 <http://wordnet-rdf.princeton.edu/rdf/id/14731522-n>
wdt:P10283 "C2909627636"
"C34628245"
wdt:P10376 "agricultural-and-biological-sciences/adenosine-deaminase"
wdt:P129 coformycin
pentostatin
wdt:P18 <http://commons.wikimedia.org/wiki/Special:FilePath/Adenosine%20deaminase%201VFL.png>
wdt:P2888 <http://purl.uniprot.org/uniprot/P00813>
wdt:P31 protein
wdt:P349 "00575923"
wdt:P352 "P00813"
wdt:P361 Metal-dependent hydrolase
adenosine deaminase
Adenosine/AMP deaminase domain, protein family
Adenosine/AMP deaminase active site, protein family
wdt:P527 Adenosine/AMP deaminase active site
Adenosine/AMP deaminase domain
wdt:P591 "3.5.4.4"
wdt:P6366 "2909476619"
"34628245"
wdt:P637 "NP_000013"
"NP_001308979"
"NP_001308980"
wdt:P638 "3IAR"
wdt:P646 "/m/04ndg6"
wdt:P680 metal ion binding
hydrolase activity
zinc ion binding
purine nucleoside binding
adenosine deaminase activity
deaminase activity
protein binding
wdt:P681 extracellular space
membrane
external side of plasma membrane
soma
cytoplasmic vesicle
dendrite cytoplasm
cytoplasmic vesicle lumen
cell junction
cell surface
cytosol
plasma membrane
cytoplasm
lysosome
wdt:P682 placenta development
liver development
lung development
negative regulation of apoptotic process
in utero embryonic development
response to hypoxia
response to vitamin E
response to hydrogen peroxide
lung alveolus development
positive regulation of T cell differentiation in thymus
positive regulation of alpha-beta T cell differentiation
negative regulation of inflammatory response
positive regulation of B cell proliferation
T cell activation
regulation of circadian sleep/wake cycle, sleep
positive regulation of T cell differentiation
purine-containing compound salvage
hypoxanthine salvage
trophectodermal cell differentiation
histamine secretion
germinal center B cell differentiation
positive regulation of germinal center formation
negative regulation of leukocyte migration
negative regulation of mature B cell apoptotic process
adenosine catabolic process
deoxyadenosine catabolic process
purine ribonucleoside monophosphate biosynthetic process
positive regulation of heart rate
purine nucleotide salvage
regulation of cell-cell adhesion mediated by integrin
response to morphine
positive regulation of smooth muscle contraction
dATP catabolic process
inosine biosynthetic process
xanthine biosynthetic process
Peyer's patch development
embryonic digestive tract development
positive regulation of calcium-mediated signaling
positive regulation of T cell receptor signaling pathway
negative regulation of adenosine receptor signaling pathway
negative regulation of penile erection
negative regulation of thymocyte apoptotic process
negative regulation of mucus secretion
nucleotide metabolic process
regulation of T cell differentiation
adenosine metabolic process
hypoxanthine biosynthetic process
positive regulation of T cell activation
cell adhesion
negative regulation of circadian sleep/wake cycle, non-REM sleep
ageing
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20ADA%20204639%20at%20fs.png>
wdt:P702 ADA
wdt:P703 man
wdt:P705 "ENSP00000361965"
"ENSP00000440946"
"ENSP00000441818"
"ENSP00000446464"
wdt:P8814 "14731522-n"
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