Langerhans-cell histiocytosis

disease involving clonal proliferation of Langerhans cells
rdfs:label
"Langerhans-cell histiocytosis"@en
skos:altLabel
"Histiocytosis X"@en
"Langerhan's cell histiocytosis"@en
"Langerhan's cell histiocytosis (disorder)"@en
"Langerhans cell granulomatosis"@en
"Letterer-Siwe disease"@en
"Letterer-Siwe disease involving intra-abdominal lymph nodes"@en
"Letterer-Siwe disease involving intrapelvic lymph nodes"@en
"Letterer-Siwe disease involving intrathoracic lymph nodes"@en
"Letterer-Siwe disease involving lymph nodes of axilla and upper limb"@en
"Letterer-Siwe disease involving lymph nodes of head, face and neck"@en
"Letterer-Siwe disease involving lymph nodes of head, face, and neck"@en
"Letterer-Siwe disease involving lymph nodes of inguinal region and lower limb"@en
"Letterer-Siwe disease involving lymph nodes of multiple sites"@en
"Letterer-Siwe disease involving spleen"@en
"Letterer-Siwe disease of intra-abdominal lymph nodes"@en
"Letterer-Siwe disease of intra-abdominal lymph nodes (disorder)"@en
"Letterer-Siwe disease of intrapelvic lymph nodes"@en
"Letterer-Siwe disease of intrapelvic lymph nodes (disorder)"@en
"Letterer-Siwe disease of intrathoracic lymph nodes"@en
"Letterer-Siwe disease of intrathoracic lymph nodes (disorder)"@en
"Letterer-Siwe disease of lymph nodes of axilla and upper limb"@en
"Letterer-Siwe disease of lymph nodes of axilla and upper limb (disorder)"@en
"Letterer-Siwe disease of lymph nodes of axilla and/or upper limb"@en
"Letterer-Siwe disease of lymph nodes of axilla and/or upper limb (disorder)"@en
"Letterer-Siwe disease of lymph nodes of head, face and neck"@en
"Letterer-Siwe disease of lymph nodes of head, face and neck (disorder)"@en
"Letterer-Siwe disease of lymph nodes of head, face and/or neck"@en
"Letterer-Siwe disease of lymph nodes of head, face and/or neck (disorder)"@en
"Letterer-Siwe disease of lymph nodes of inguinal region amd/or lower limb"@en
"Letterer-Siwe disease of lymph nodes of inguinal region and lower limb"@en
"Letterer-Siwe disease of lymph nodes of inguinal region and lower limb (disorder)"@en
"Letterer-Siwe disease of lymph nodes of inguinal region and/or lower limb"@en
"Letterer-Siwe disease of lymph nodes of inguinal region and/or lower limb (disorder)"@en
"Letterer-Siwe disease of lymph nodes of multiple sites"@en
"Letterer-Siwe disease of lymph nodes of multiple sites (disorder)"@en
"Letterer-Siwe disease of spleen"@en
"Letterer-Siwe disease of spleen (disorder)"@en
schema:description
"disease involving clonal proliferation of Langerhans cells"@en
schema:dateModified "2026-11-01T15:13:58+00:00"^^xsd:dateTime
schema:version 2563444063
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p:direct-normalized/P4527 <http://data.parliament.uk/terms/454847>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D006646>
p:direct-normalized/P508 <http://purl.org/bncf/tid/61925>
p:direct-normalized/P5806 <http://snomed.info/id/65399007>
p:direct-normalized/P6366 <https://makg.org/entity/2777484599>
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p:direct-normalized/P665 <http://www.kegg.jp/entry/H01512>
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<http://id.nlm.nih.gov/mesh/C15.604.250.400>
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wdt:P10283 "C2777484599"
"C2908924797"
wdt:P11143 "Langerhans cell histiocytosis"
wdt:P1193 0.00005^^xsd:decimal
wdt:P138 Langerhans cell
wdt:P14914 "D00389"
wdt:P1550 "389"
wdt:P1692 "202.5"
wdt:P1748 "C3107"
"C3160"
"C6920"
wdt:P18 <http://commons.wikimedia.org/wiki/Special:FilePath/Hans-Schuller-Christian.jpg>
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wdt:P1995 oncology
wdt:P2293 BRAF
NRAS
MAP2K1
wdt:P2581 "00978670n"
wdt:P279 histiocytosis
wdt:P2841 any age
wdt:P2888 <http://identifiers.org/doid/DOID:2571>
<http://purl.obolibrary.org/obo/DOID_2571>
<http://www.orpha.net/ORDO/Orphanet_389>
wdt:P2892 "C0019621"
"C0023381"
wdt:P31 type of disease
wdt:P373 "Langerhans cell histiocytosis"
wdt:P3827 "langerhans-cell-histiocytosis"
wdt:P3841 "HP:0034769"
wdt:P4229 "C96.0"
"C96.5"
"C96.6"
wdt:P4233 "langerhans-cell-histiocytosis"
wdt:P4317 "6858"
wdt:P4527 "454847"
wdt:P486 "D006646"
wdt:P492 "246400"
"604856"
wdt:P494 "C96.6"
wdt:P5008 WikiProject Medicine
wdt:P508 "61925"
wdt:P557 "5906"
wdt:P563 "9751/1"
"9751/3"
"9752/3"
wdt:P5806 "65399007"
wdt:P6366 "2777484599"
"2910305713"
wdt:P6532 Growth delay
splenomegaly
interstitial lung disease
deafness
hepatomegaly
Skin rash
mild cognitive impairment
cerebellar ataxia
hypoalbuminemia
sclerosing cholangitis
osteolysis
diabetes insipidus
dysarthria
mouth ulcer
bone pain
cough
Langerhans-cell histiocytosis
fever
genital ulcer
leukopenia
thrombocytopenia
weight loss
respiratory failure
lymphadenopathy
liver failure
eczema
wdt:P665 "H01512"
wdt:P672 "C08.381.483.375"
"C15.604.250.400"
wdt:P673 "1100579"
wdt:P699 "DOID:2571"
wdt:P7329 "2B31.2"
wdt:P7464 "langerhans-cell-histiocytosis"
wdt:P7807 "1388720498"
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wdt:P989 <http://commons.wikimedia.org/wiki/Special:FilePath/Nl-Langerhanscelhistiocytose-article.ogg>
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