|
rdfs:label
|
"BLK"@pt
"BLK proto-oncogene, Src family tyrosine kinase"@en
"Blk"@ru
"Tirosin-chinasi B-linfoide"@it
|
|
skos:altLabel
|
"B lymphoid tyrosine kinase"@en
"BLK"@en
"BLK"@it
"BLK nonreceptor tyrosine kinase"@en
"Chinasi B-linfocitica"@it
"b lymphocyte kinase"@en
"p55-Blk"@en
"tyrosine-protein kinase Blk"@en
|
|
schema:description
|
"Protein in Homo sapiens"@de
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in BLK proto-oncogene, Src family tyrosine kinase"@nl
"protèin"@ace
"protéine"@fr
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
|
|
schema:dateModified
|
"2026-07-23T06:50:41+00:00"^^xsd:dateTime
|
|
schema:version
|
2521519568
|
|
wikibase:identifiers
|
14
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|
wikibase:sitelinks
|
0
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|
wikibase:statements
|
66
|
|
p:P129
|
wd:statement/Q401536-3F6EB365-57F6-4D32-B4F5-255AEC9BC5D3
|
|
p:P2888
|
wd:statement/Q401536-FC30EE65-4D39-4BFC-A0FB-9CAFDCE69DE3
|
|
p:P31
|
wd:statement/Q401536-A0BD9F7C-A3DA-44D4-9777-9799820AE562
|
|
p:P352
|
wd:statement/Q401536-95498260-A4F8-4D63-BA5F-D33B30AEEAF4
|
|
p:P361
|
wd:statement/Q401536-82800545-2ACF-43D3-9363-C008F902A680
|
|
wd:statement/Q401536-84A2DC9F-540C-4701-A5A0-DDB0B67E863D
|
|
wd:statement/Q401536-890BF041-855E-4B8A-8C04-9D321728FD9E
|
|
wd:statement/Q401536-A42F0B9B-E3E3-48BF-A37C-70D5B97802BA
|
|
wd:statement/Q401536-AB5159A8-B976-4647-8FD7-E4BC6847053E
|
|
wd:statement/Q401536-B3D4085A-87AB-4ED2-9EBF-F1D38FC7352C
|
|
wd:statement/Q401536-C7A669FF-DCA6-4054-93BC-834F47AE166C
|
|
wd:statement/Q401536-D6961D50-3FD9-4814-AE97-A3E6592B3336
|
|
wd:statement/Q401536-D99B6F81-F4E8-475E-AEA4-A8F1E9A3D66D
|
|
wd:statement/Q401536-E8AEA278-F433-42B7-B2FA-5A0E70178AF7
|
|
p:P527
|
wd:statement/Q401536-151DDE0E-7CC6-4B41-9E86-E982EDBFDD04
|
|
wd:statement/Q401536-31E19B0B-7BC4-45D6-83FC-F47632EA8CCE
|
|
wd:statement/Q401536-41A18E85-3EB2-450C-A1C3-AB56506C947F
|
|
wd:statement/Q401536-802C6FDB-9009-4BCF-A8DC-976E78B92AF9
|
|
wd:statement/Q401536-8B09A296-BCDE-4119-914E-71B45307CDF1
|
|
wd:statement/Q401536-C1C97C7C-E915-4413-B9CB-64EEAEC894E6
|
|
wd:statement/Q401536-C3692FD5-C7ED-4907-8634-17EC0829392B
|
|
p:P591
|
wd:statement/Q401536-1EE6DD76-D7B1-4401-8EC5-61EAAD614438
|
|
p:P637
|
wd:statement/Q401536-019C8B3A-540A-40C9-9C1E-E53245495F46
|
|
wd:statement/Q401536-1E857B76-DA1E-4BDD-A92B-2D60EFE72EBE
|
|
wd:statement/Q401536-54A6F440-0947-4C16-B63E-E7F1BE8A5D52
|
|
wd:statement/Q401536-6B1278EC-BBB5-43D7-AEAE-AB3D405E48C1
|
|
wd:statement/Q401536-9DEE5A4F-42C9-482A-86CC-6905EF34B0A7
|
|
wd:statement/Q401536-ADCC8A65-7586-4825-AC8D-CCD77AC773A0
|
|
wd:statement/Q401536-BCA3D808-A249-4D13-A953-79CB04517E56
|
|
p:P646
|
wd:statement/Q401536-D1C99C7D-BB5F-4DAD-ADF4-C6CF4D24C2CB
|
|
p:P680
|
wd:statement/Q401536-225CC97D-2272-4DDF-9410-242FE749CE07
|
|
wd:statement/Q401536-302CB78F-AD41-456D-8A76-9BFDC4480CA2
|
|
wd:statement/Q401536-55E59469-53EB-4401-B0BC-16F0D8FDF4AB
|
|
wd:statement/Q401536-87CC2B46-F4C0-41A2-990A-0CE296E8AD62
|
|
wd:statement/Q401536-8A3583A3-B1B1-40E8-A951-BC62904533A4
|
|
wd:statement/Q401536-8B22C401-5B33-49F8-81F5-0E77D86E964F
|
|
wd:statement/Q401536-A1853BFD-D443-4E0F-8935-547B1C923145
|
|
wd:statement/Q401536-A6CDE0EF-4554-46CE-8CC0-7E16167BF0F1
|
|
wd:statement/Q401536-DA8D8C85-2453-41CE-B9EC-E3252064A1D2
|
|
wd:statement/Q401536-ED0AAFBB-03C2-4B07-9096-DA9DD1ECE087
|
|
wd:statement/Q401536-FABA891F-9AFA-4804-A24E-FF78A3D350CB
|
|
p:P681
|
wd:statement/Q401536-0C0ED8A8-A969-4B59-81CF-F0CEAF1D646E
|
|
wd:statement/Q401536-1794DB6F-01AD-4468-AC1C-8A8F830F5114
|
|
wd:statement/Q401536-9A64E111-1551-4A03-A4AF-188C821AC663
|
|
wd:statement/Q401536-E5590F93-893D-4A42-BF05-CA7AA28D3CE2
|
|
p:P682
|
wd:statement/Q401536-04E431BC-0250-41CA-B9CC-176625395520
|
|
wd:statement/Q401536-5543D771-DC0A-4A52-802F-8FE91C7EB5B2
|
|
wd:statement/Q401536-67C2BD00-E6D4-4308-B02C-2D287B586363
|
|
wd:statement/Q401536-7939DB37-2E3B-4CE4-913E-99C49DFB4C1E
|
|
wd:statement/Q401536-9A45050C-9A52-401E-B36A-CAA3ADE00586
|
|
wd:statement/Q401536-B7271D6B-631B-445A-A7CB-73CCC2842090
|
|
wd:statement/Q401536-CE8F0605-F84A-4751-BFF0-773718CC77EB
|
|
wd:statement/Q401536-D66E2E86-B5DB-41D8-B4DB-208D3D2878DF
|
|
wd:statement/Q401536-D890405A-5497-4E60-A28C-EBE56A05FC4B
|
|
wd:statement/Q401536-E93F8113-E51D-4EDE-94FD-57CE8A926A99
|
|
wd:statement/Q401536-F01BD19B-7B3F-4DC5-8C57-EA88F48FE024
|
|
wd:statement/Q401536-F19404E4-FE85-4E0A-9818-BA2D065E1BBE
|
|
wd:statement/Q401536-F3EAB76A-BF01-4E0F-81A2-F8D5CE0FFFF8
|
|
p:P692
|
wd:statement/Q401536-59B00FC1-CAFE-4E68-A45D-4120931A765E
|
|
p:P702
|
wd:statement/Q401536-773F3460-27CB-411E-9440-1B5CBF697D0F
|
|
p:P703
|
wd:statement/Q401536-45CD7980-8071-4F54-854F-A3F5F27420E0
|
|
p:P705
|
wd:statement/Q401536-1E028EA5-1EDD-4EFF-BBF2-826809A89C34
|
|
wd:statement/Q401536-9636B45C-AAF7-4A8D-94A6-EF74D3044CCB
|
|
wd:statement/Q401536-EAE57365-8BFC-4D9E-BED7-C4BE1EC90F12
|
|
wd:statement/Q401536-EEA5293F-3D99-4B46-823E-E7D6A03D6468
|
|
wd:statement/Q401536-FD7AD0CD-CFCA-4176-890D-DA88B88C4DE6
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P51451>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001317394>
|
|
<http://purl.uniprot.org/refseq/NP_001706>
|
|
<http://purl.uniprot.org/refseq/XP_011542126>
|
|
<http://purl.uniprot.org/refseq/XP_011542127>
|
|
<http://purl.uniprot.org/refseq/XP_011542129>
|
|
<http://purl.uniprot.org/refseq/XP_011542130>
|
|
<http://purl.uniprot.org/refseq/XP_011542131>
|
|
wdt:P129
|
ibrutinib
|
|
wdt:P2888
|
<http://purl.uniprot.org/uniprot/P51451>
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P51451"
|
|
wdt:P361
|
Protein kinase-like domain superfamily
|
|
SH3-like domain superfamily
|
|
SH2 domain superfamily
|
|
Tyrosine-protein kinase, catalytic domain, protein family
|
|
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
|
|
Protein kinase domain, protein family
|
|
SH3 domain, protein family
|
|
SH2 domain, protein family
|
|
Tyrosine-protein kinase Blk, SH2 domain, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P527
|
tyrosine-protein kinase, catalytic domain
|
|
serine-threonine/tyrosine-protein kinase, catalytic domain
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
SH3 domain
|
|
SH2 domain
|
|
Tyrosine-protein kinase Blk, SH2 domain
|
|
wdt:P591
|
"2.7.10.2"
|
|
wdt:P637
|
"NP_001317394"
|
|
"NP_001706"
|
|
"XP_011542126"
|
|
"XP_011542127"
|
|
"XP_011542129"
|
|
"XP_011542130"
|
|
"XP_011542131"
|
|
wdt:P646
|
"/m/03gz0m8"
|
|
wdt:P680
|
ATP binding
|
|
signaling receptor binding
|
|
protein kinase activity
|
|
transferase activity
|
|
nucleotide binding
|
|
kinase activity
|
|
protein tyrosine kinase activity
|
|
non-membrane spanning protein tyrosine kinase activity
|
|
protein binding
|
|
wdt:P681
|
membrane
|
|
extrinsic component of cytoplasmic side of plasma membrane
|
|
cytosol
|
|
plasma membrane
|
|
wdt:P682
|
peptidyl-tyrosine phosphorylation
|
|
regulation of cell population proliferation
|
|
intracellular signal transduction
|
|
positive regulation of insulin secretion
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
|
B cell receptor signaling pathway
|
|
peptidyl-tyrosine autophosphorylation
|
|
regulation of B cell receptor signaling pathway
|
|
cell migration
|
|
cell differentiation
|
|
phosphorylation
|
|
innate immune response
|
|
protein phosphorylation
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20BLK%20206255%20at%20fs.png>
|
|
wdt:P702
|
BLK
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000259089"
|
|
"ENSP00000433663"
|
|
"ENSP00000494522"
|
|
"ENSP00000494690"
|
|
"ENSP00000496520"
|
