|
rdfs:label
|
"KRAS"@fr
"KRAS"@ja
"KRAS"@pt
"KRAS"@ru
"KRAS proto-oncogene, GTPase"@en
"KRAS proto-oncogene, GTPase"@nl
|
|
skos:altLabel
|
"GTPase KRas"@en
"K-Ras 2"@en
"K-ras p21 protein"@en
"KRAS"@en
"KRAS protein, human"@en
"Ki-Ras"@en
"Kirsten rat sarcoma viral oncogene homolog"@en
"Kirsten rat sarcoma viral proto-oncogene"@en
"PR310 c-K-ras oncogene"@en
"c-K-ras"@en
"c-Ki-ras"@en
"c-Kirsten-ras protein"@en
"cellular c-Ki-ras2 proto-oncogene"@en
"cellular transforming proto-oncogene"@en
"oncogene KRAS2"@en
"transforming protein p21"@en
"v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog"@en
"Протоонкоген KRAS"@ru
|
|
schema:description
|
"Protein in Homo sapiens"@de
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in KRAS proto-oncogene, GTPase"@nl
"protèin"@ace
"protéine"@fr
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
"智人發現的哺乳動物蛋白"@zh
|
|
schema:dateModified
|
"2026-07-23T06:56:35+00:00"^^xsd:dateTime
|
|
schema:version
|
2521520778
|
|
wikibase:identifiers
|
52
|
|
wikibase:sitelinks
|
0
|
|
wikibase:statements
|
124
|
|
p:P129
|
wd:statement/Q4042017-496E80BE-08EB-49A8-BBCB-560BE2608852
|
|
p:P2888
|
wd:statement/Q4042017-AA054421-AC47-4B3B-9433-9C7ADB8F0AC7
|
|
wd:statement/Q4042017-DD9632A2-61C2-458C-86B9-684EE67BEF53
|
|
wd:statement/Q4042017-DFE3457C-8650-49D1-B3B5-82332F59F33F
|
|
p:P2892
|
wd:statement/Q4042017-812DC356-8ED3-4209-9A89-4BB56091C227
|
|
p:P31
|
wd:statement/Q4042017-203E39C8-99DC-45E8-A67E-92DEF0D35AB0
|
|
p:P352
|
wd:statement/Q4042017-F074D2FB-3BF8-45B7-BE2B-5FBC37D5E8E2
|
|
p:P361
|
wd:statement/Q4042017-26A0CAB4-64B1-43BC-881E-4BA5DEC1F192
|
|
wd:statement/Q4042017-36A25017-1A2B-4CEA-AFCC-BAC72E19BB20
|
|
wd:statement/Q4042017-F89E1FAE-CE11-4C79-B83F-87F96679877E
|
|
p:P486
|
wd:statement/Q4042017-2b7c9b55-47cb-212d-6a58-f6d61c872e20
|
|
p:P527
|
wd:statement/Q4042017-202ED5B2-CA25-402E-9CAF-5577E0D81A21
|
|
p:P591
|
wd:statement/Q4042017-9B135220-E8F7-4F42-8614-D86FF4736A36
|
|
p:P637
|
wd:statement/Q4042017-110E1ADB-0EC7-42D8-920B-555A04993AB8
|
|
wd:statement/Q4042017-625E4AF3-17BE-45E4-9F53-BC28EEE4AF9D
|
|
wd:statement/Q4042017-8F17FB32-EBC4-40B4-BB6B-3D25920F7758
|
|
wd:statement/Q4042017-9FC84DE9-296C-4BD6-9215-466A442F5C5D
|
|
p:P638
|
wd:statement/Q4042017-1A106D51-EB4A-45AF-8CD4-00863B892A11
|
|
wd:statement/Q4042017-1BF9F423-C5D4-4639-8324-D8CCC9E2E443
|
|
wd:statement/Q4042017-211BC7F5-4DC3-4398-983E-5608D2BC235B
|
|
wd:statement/Q4042017-2BD74E73-A44D-4B19-9355-208D5CF8251A
|
|
wd:statement/Q4042017-360B2F69-E24A-4A66-BF1E-EDF3EC7DA37C
|
|
wd:statement/Q4042017-37ECCB62-8675-4657-8F43-95738651DB96
|
|
wd:statement/Q4042017-3A59C70B-3B62-4348-826F-0D2F3BDE39F2
|
|
wd:statement/Q4042017-3B84130E-5A78-4749-8300-B6107400C9B9
|
|
wd:statement/Q4042017-3BD8694A-8367-4D20-AF61-9427D295353C
|
|
wd:statement/Q4042017-3CD29861-15B4-44DA-838F-A55E0664E66C
|
|
wd:statement/Q4042017-3D9F193F-6EA7-47E3-BEE1-E6F2113471CA
|
|
wd:statement/Q4042017-44C35E54-75D1-4728-ABE9-2F9F34BE28B0
|
|
wd:statement/Q4042017-496A6A1F-06C2-4596-A3BB-6AB3F9DA2AFF
|
|
wd:statement/Q4042017-5894F721-65C3-414F-A532-CE8F4C69C333
|
|
wd:statement/Q4042017-598362F8-BA1F-4899-9C72-44C6B4F72C5B
|
|
wd:statement/Q4042017-62F79C7A-E936-40E3-ACA9-AF117A94A54F
|
|
wd:statement/Q4042017-6D059969-F310-47A7-A58A-92D74CE78407
|
|
wd:statement/Q4042017-734787BE-0355-4C6F-A7C7-DCC4445FCBBE
|
|
wd:statement/Q4042017-79E6AD83-DEAD-44DF-8915-7EBF55DD6C5B
|
|
wd:statement/Q4042017-8A403BE4-2470-4A2F-ABDA-B6C21CF68D63
|
|
wd:statement/Q4042017-8C6CA5C4-3BA6-4A8A-B9D2-4C1397559C80
|
|
wd:statement/Q4042017-8E4BB87D-D519-4F59-B685-9FBC85C27718
|
|
wd:statement/Q4042017-91E9D043-7046-4B12-9E35-F49CFC4334F8
|
|
wd:statement/Q4042017-96A62128-26C5-4756-85B1-381A309E2CE9
|
|
wd:statement/Q4042017-A47B1F5D-AD39-4C38-A9A1-A14E8E1A7378
|
|
wd:statement/Q4042017-A757BDEF-017C-46EE-A7BD-FBFC89ECE7E5
|
|
wd:statement/Q4042017-A81B79A3-E4E5-4E82-B1B1-FABD2FE9317A
|
|
wd:statement/Q4042017-AA707599-6836-48BD-ACEC-1E6253B19A75
|
|
wd:statement/Q4042017-AA87407D-33C7-44F0-AAF2-CADC002E5E5C
|
|
wd:statement/Q4042017-B7F0F7D5-671C-48A8-89B1-E5BE9821BD80
|
|
wd:statement/Q4042017-C28A41F3-87F5-4F1A-9A82-3198A766F4D4
|
|
wd:statement/Q4042017-C78ECF98-D4A6-4901-ACFD-1C3110A69229
|
|
wd:statement/Q4042017-C8741793-3191-43E4-AE96-EBD7E902C261
|
|
wd:statement/Q4042017-D108F512-373D-4253-AF7E-41986F10A908
|
|
wd:statement/Q4042017-D615F232-2B13-4A8B-9A66-8AB9340332D0
|
|
wd:statement/Q4042017-D768DDD7-6367-4F6A-91E0-4320EE4BE1CA
|
|
wd:statement/Q4042017-DEDA9E9A-D4B6-4082-B23C-5949F8E1303A
|
|
wd:statement/Q4042017-E9D161FA-37AB-4D44-BAA8-AEDBE4362A75
|
|
wd:statement/Q4042017-EFEC1449-DCDF-4BB5-A55B-F14C78797C4D
|
|
wd:statement/Q4042017-F8FFD07C-F190-41FF-9EA7-23C6118322D5
|
|
wd:statement/Q4042017-FA0AC061-1AE6-4C10-A48C-7AD2F15EB0CE
|
|
p:P680
|
wd:statement/Q4042017-0EA487A9-53E0-4CBF-80F3-FA2B028AC6C9
|
|
wd:statement/Q4042017-1004CA24-95B7-4CD9-A2D4-85FFBFC76495
|
|
wd:statement/Q4042017-1B03845F-5E15-4AEC-935E-DB7BC7F6B05A
|
|
wd:statement/Q4042017-270C72A3-0C4D-4233-96EA-B6762BF72DF8
|
|
wd:statement/Q4042017-33342635-8DF1-4BBC-A8B7-CB2FD46AB0EA
|
|
wd:statement/Q4042017-58DDBD1A-E683-4C60-9EE3-FD92ECCBEA1F
|
|
wd:statement/Q4042017-59A5F552-B578-468F-A702-46FE1E5DF543
|
|
wd:statement/Q4042017-5FC8BEE4-30EF-494C-B12E-AD24906F6B88
|
|
wd:statement/Q4042017-656A508E-0445-48DD-AFEE-4B523D0A42E9
|
|
wd:statement/Q4042017-6ADDA858-462A-4A9C-A66D-F84F9F7EA86E
|
|
wd:statement/Q4042017-951FB882-442D-45B3-91FE-7A0384C1DE47
|
|
wd:statement/Q4042017-AA05D7F0-1E25-4A51-A5D9-45ECE9241B45
|
|
p:P681
|
wd:statement/Q4042017-0AB841EF-B542-44AB-ACA8-564254FE2789
|
|
wd:statement/Q4042017-10F94C11-CB9A-496E-B719-3F8AB3153E7E
|
|
wd:statement/Q4042017-17F3B32D-D71E-4044-8C71-7EDE9CDDEE7C
|
|
wd:statement/Q4042017-21CE423B-A3E2-4DDD-98B0-599CE2ADED5C
|
|
wd:statement/Q4042017-256591DB-2DA0-4D3F-8CB2-536B5ADB46BE
|
|
wd:statement/Q4042017-60604459-92E1-41FD-85C8-F407A2845466
|
|
wd:statement/Q4042017-9787907B-9AFC-4087-BCA3-32696F6EED13
|
|
wd:statement/Q4042017-983B9ECE-1099-4FA9-9F4B-ADE3DF2B9F1C
|
|
wd:statement/Q4042017-D74448E3-5CF7-450D-9E6D-A79B90AD59C9
|
|
wd:statement/Q4042017-DC566117-3FA0-4C4E-BB9A-B37543F69E9F
|
|
wd:statement/Q4042017-E0309C65-053C-4BBB-8106-8B7E7A2C8D84
|
|
p:P682
|
wd:statement/Q4042017-04F1E6CE-8D65-4240-9C86-84522F5E65B8
|
|
wd:statement/Q4042017-0DD0B45B-74A8-467C-BF39-1463BA51FE9B
|
|
wd:statement/Q4042017-12ADF978-CE15-420F-A118-EF84CFC2C256
|
|
wd:statement/Q4042017-24FFE75D-FCAC-4E0F-8D7A-82757F340E87
|
|
wd:statement/Q4042017-277F1AB2-E11F-4FD2-8374-0CB6BB819DE6
|
|
wd:statement/Q4042017-43FE849E-01A3-4C06-9E7C-BAFEB54BAE8B
|
|
wd:statement/Q4042017-498FB8DE-C456-46A1-9FB3-1AD9CB7F19AC
|
|
wd:statement/Q4042017-4D1405EE-0711-495E-8CDD-16AF60FFAEC6
|
|
wd:statement/Q4042017-54FD4032-D892-4746-8DF2-5D1D3C4BE0DB
|
|
wd:statement/Q4042017-56A59263-C919-4D80-923A-81937C5519F4
|
|
wd:statement/Q4042017-61996EDE-AA61-40F0-9234-404F174E8B6B
|
|
wd:statement/Q4042017-62745FEF-7822-4E29-9127-79B232213E1E
|
|
wd:statement/Q4042017-67701B00-56B0-46A8-A46F-14A9C1DCD42D
|
|
wd:statement/Q4042017-74F89ED0-7723-4A26-87C0-D07B50EA5304
|
|
wd:statement/Q4042017-7BF14993-4EF4-4327-ABC9-FE790914EFF0
|
|
wd:statement/Q4042017-7E4F69EF-4352-4364-B5A6-EBC501D40D11
|
|
wd:statement/Q4042017-807F26E9-B6AB-4858-AC86-D341398E6E05
|
|
wd:statement/Q4042017-90BA1918-5C65-4BD3-A22B-DD6138446F85
|
|
wd:statement/Q4042017-939A3CAB-98F6-4C0C-8D62-9094F155920B
|
|
wd:statement/Q4042017-A301477A-15D9-4E87-A2ED-13C817B36DC8
|
|
wd:statement/Q4042017-A4A6918E-5F0D-4C8A-BE03-63BB71E2A1CA
|
|
wd:statement/Q4042017-BA243812-3DCB-4673-9CB3-EC287ABC0882
|
|
wd:statement/Q4042017-BB94C966-F555-4BE9-BA2C-3F4E66B58158
|
|
wd:statement/Q4042017-C341B875-6B84-4E22-8927-DD582579FC6E
|
|
wd:statement/Q4042017-C3BD8B73-505B-4A43-AD5D-70D3DE575285
|
|
wd:statement/Q4042017-C53E16D9-DB81-459D-9185-A168FC7A2B4D
|
|
wd:statement/Q4042017-C6B1759C-5463-4060-AA30-94137F9F9063
|
|
wd:statement/Q4042017-D77E9EC9-7B43-4F7B-A957-714ECBED1466
|
|
wd:statement/Q4042017-D7E286CC-FFF2-4A12-A2C7-916EFFFF25DA
|
|
wd:statement/Q4042017-D90A888D-98C0-4463-B434-F11AE5A72B3B
|
|
wd:statement/Q4042017-DBB89497-7426-4D41-B3AA-53D19A33380E
|
|
wd:statement/Q4042017-DC7DF038-0CA4-4F26-9F0E-D6FB942D5B91
|
|
wd:statement/Q4042017-DD945A08-168D-4A59-8085-1E1C6958075B
|
|
wd:statement/Q4042017-E052A4E7-4F14-4D93-BC64-957AA54313B8
|
|
wd:statement/Q4042017-E355C69F-D056-4E15-B605-CEBBAB98E510
|
|
wd:statement/Q4042017-EE714BDE-2CE1-4BDF-BDC5-6948E024219C
|
|
p:P692
|
wd:statement/Q4042017-F3A59662-1068-4387-B6B5-88F42C65933C
|
|
p:P702
|
wd:statement/Q4042017-14D1DB70-B385-43E7-9793-16020AD63EB7
|
|
p:P703
|
wd:statement/Q4042017-7E53EC53-4630-459A-9F0D-D886DE2D9240
|
|
p:P705
|
wd:statement/Q4042017-73B81EAB-8B48-4E3E-828B-B4E0343721F2
|
|
wd:statement/Q4042017-8E6B378F-9002-4AD1-8F03-D1BEB3FB7C13
|
|
wd:statement/Q4042017-C1846D6F-01B5-42AD-9913-AAFC4AAA8159
|
|
wd:statement/Q4042017-E4DF552E-3DFB-4EE8-BE13-07EC1208B6D4
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P01116>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/C117307>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001356715>
|
|
<http://purl.uniprot.org/refseq/NP_001356716>
|
|
<http://purl.uniprot.org/refseq/NP_004976>
|
|
<http://purl.uniprot.org/refseq/NP_203524>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1D8D>
|
|
<https://rdf.wwpdb.org/pdb/1D8E>
|
|
<https://rdf.wwpdb.org/pdb/3GFT>
|
|
<https://rdf.wwpdb.org/pdb/4DSN>
|
|
<https://rdf.wwpdb.org/pdb/4DSO>
|
|
<https://rdf.wwpdb.org/pdb/4DST>
|
|
<https://rdf.wwpdb.org/pdb/4DSU>
|
|
<https://rdf.wwpdb.org/pdb/4EPR>
|
|
<https://rdf.wwpdb.org/pdb/4EPT>
|
|
<https://rdf.wwpdb.org/pdb/4EPV>
|
|
<https://rdf.wwpdb.org/pdb/4EPW>
|
|
<https://rdf.wwpdb.org/pdb/4EPX>
|
|
<https://rdf.wwpdb.org/pdb/4EPY>
|
|
<https://rdf.wwpdb.org/pdb/4L8G>
|
|
<https://rdf.wwpdb.org/pdb/4LDJ>
|
|
<https://rdf.wwpdb.org/pdb/4LPK>
|
|
<https://rdf.wwpdb.org/pdb/4LRW>
|
|
<https://rdf.wwpdb.org/pdb/4LUC>
|
|
<https://rdf.wwpdb.org/pdb/4LV6>
|
|
<https://rdf.wwpdb.org/pdb/4LYF>
|
|
<https://rdf.wwpdb.org/pdb/4LYH>
|
|
<https://rdf.wwpdb.org/pdb/4LYJ>
|
|
<https://rdf.wwpdb.org/pdb/4M1O>
|
|
<https://rdf.wwpdb.org/pdb/4M1S>
|
|
<https://rdf.wwpdb.org/pdb/4M1T>
|
|
<https://rdf.wwpdb.org/pdb/4M1W>
|
|
<https://rdf.wwpdb.org/pdb/4M1Y>
|
|
<https://rdf.wwpdb.org/pdb/4M21>
|
|
<https://rdf.wwpdb.org/pdb/4M22>
|
|
<https://rdf.wwpdb.org/pdb/4NMM>
|
|
<https://rdf.wwpdb.org/pdb/4OBE>
|
|
<https://rdf.wwpdb.org/pdb/4PZY>
|
|
<https://rdf.wwpdb.org/pdb/4PZZ>
|
|
<https://rdf.wwpdb.org/pdb/4Q01>
|
|
<https://rdf.wwpdb.org/pdb/4Q02>
|
|
<https://rdf.wwpdb.org/pdb/4Q03>
|
|
<https://rdf.wwpdb.org/pdb/4QL3>
|
|
<https://rdf.wwpdb.org/pdb/4TQ9>
|
|
<https://rdf.wwpdb.org/pdb/4TQA>
|
|
<https://rdf.wwpdb.org/pdb/4WA7>
|
|
<https://rdf.wwpdb.org/pdb/5F2E>
|
|
wdt:P129
|
lonafarnib
|
|
wdt:P2888
|
<http://purl.uniprot.org/uniprot/P01116>
|
|
<https://identifiers.org/uniprot:P01116>
|
|
<https://www.ncbi.nlm.nih.gov/protein/P01116>
|
|
wdt:P2892
|
"C0763464"
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P01116"
|
|
wdt:P361
|
P-loop containing nucleoside triphosphate hydrolase
|
|
small GTPase superfamily, ras-type
|
|
Small GTP-binding protein domain family
|
|
wdt:P486
|
"C117307"
|
|
wdt:P527
|
small GTP-binding protein domain
|
|
wdt:P591
|
"3.6.5.2"
|
|
wdt:P637
|
"NP_001356715"
|
|
"NP_001356716"
|
|
"NP_004976"
|
|
"NP_203524"
|
|
wdt:P638
|
"1D8D"
|
|
"1D8E"
|
|
"3GFT"
|
|
"4DSN"
|
|
"4DSO"
|
|
"4DST"
|
|
"4DSU"
|
|
"4EPR"
|
|
"4EPT"
|
|
"4EPV"
|
|
"4EPW"
|
|
"4EPX"
|
|
"4EPY"
|
|
"4L8G"
|
|
"4LDJ"
|
|
"4LPK"
|
|
"4LRW"
|
|
"4LUC"
|
|
"4LV6"
|
|
"4LYF"
|
|
"4LYH"
|
|
"4LYJ"
|
|
"4M1O"
|
|
"4M1S"
|
|
"4M1T"
|
|
"4M1W"
|
|
"4M1Y"
|
|
"4M21"
|
|
"4M22"
|
|
"4NMM"
|
|
"4OBE"
|
|
"4PZY"
|
|
"4PZZ"
|
|
"4Q01"
|
|
"4Q02"
|
|
"4Q03"
|
|
"4QL3"
|
|
"4TQ9"
|
|
"4TQA"
|
|
"4WA7"
|
|
"5F2E"
|
|
wdt:P680
|
identical protein binding
|
|
nucleotide binding
|
|
GTP binding
|
|
GTPase activity
|
|
LRR domain binding
|
|
GMP binding
|
|
GDP binding
|
|
protein binding
|
|
protein-containing complex binding
|
|
wdt:P681
|
membrane
|
|
extrinsic component of cytoplasmic side of plasma membrane
|
|
cytosol
|
|
plasma membrane
|
|
mitochondrion
|
|
membrane raft
|
|
cytoplasm
|
|
focal adhesion
|
|
wdt:P682
|
liver development
|
|
Ras protein signal transduction
|
|
positive regulation of cell population proliferation
|
|
positive regulation of gene expression
|
|
MAPK cascade
|
|
positive regulation of nitric-oxide synthase activity
|
|
positive regulation of NF-kappaB transcription factor activity
|
|
leukocyte migration
|
|
positive regulation of protein phosphorylation
|
|
female pregnancy
|
|
negative regulation of neuron apoptotic process
|
|
response to glucocorticoid
|
|
regulation of long-term neuronal synaptic plasticity
|
|
negative regulation of cell differentiation
|
|
striated muscle cell differentiation
|
|
epithelial tube branching involved in lung morphogenesis
|
|
cytokine-mediated signaling pathway
|
|
regulation of protein stability
|
|
homeostasis of number of cells within a tissue
|
|
epidermal growth factor receptor signaling pathway
|
|
positive regulation of MAP kinase activity
|
|
actin cytoskeleton organization
|
|
Fc-epsilon receptor signaling pathway
|
|
regulation of synaptic transmission, GABAergic
|
|
positive regulation of Rac protein signal transduction
|
|
forebrain astrocyte development
|
|
positive regulation of cellular senescence
|
|
response to mineralocorticoid
|
|
axon guidance
|
|
stimulatory C-type lectin receptor signaling pathway
|
|
ERBB2 signaling pathway
|
|
response to isolation stress
|
|
endocrine signaling
|
|
visual learning
|
|
signal transduction
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20KRAS%20204009%20s%20at%20fs.png>
|
|
wdt:P702
|
KRAS
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000256078"
|
|
"ENSP00000308495"
|
|
"ENSP00000451856"
|
|
"ENSP00000452512"
|
