SHMARQL

Nuclear factor kappa B subunit 1

<http://www.wikidata.org/entity/Q4044834>

mammalian protein found in Homo sapiens
rdfs:label
"Nuclear factor kappa B subunit 1"@en
skos:altLabel "DNA-binding factor KBF1"@en
"EBP-1"@en
"NF-kappabeta"@en
"NFKB1"@en
"nuclear factor NF-kappa-B p105 subunit"@en
"nuclear factor NF-kappa-B p50 subunit"@en
"nuclear factor kappa-B DNA binding subunit"@en
"nuclear factor of kappa light polypeptide gene enhancer in B-cells 1"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2025-07-23T21:46:04+00:00"^^xsd:dateTime
schema:version 2383306254
wikibase:identifiers 33
wikibase:sitelinks 0
wikibase:statements 130
p:P2892 wd:statement/Q4044834-59CAE10C-253A-48B9-9A2D-2453808B1CD5
p:P31 wd:statement/Q4044834-BDB96271-88AF-44D3-B404-27A83A03EFE4
p:P352 wd:statement/Q4044834-81CB0D22-5647-4022-BE88-AFDB0BAB7FF1
p:P361 wd:statement/Q4044834-137A1AEA-92CA-4DAE-B51F-76258DA7AD8F
wd:statement/Q4044834-16760BC9-6223-40E4-8DED-464C7EE67F07
wd:statement/Q4044834-180DE8CD-EA44-4DBA-8819-0D7C58BB395A
wd:statement/Q4044834-3FDCAF5C-D994-4471-AFE6-FB2701D2B26F
wd:statement/Q4044834-41268078-9733-4468-83ED-3140158F601E
wd:statement/Q4044834-470BE699-B6CF-45A4-AEE2-8D7D15A14855
wd:statement/Q4044834-4B03E91F-DCC7-496E-9AEB-21993383789D
wd:statement/Q4044834-6018D11E-CB2E-4E3F-B668-A95544D76CA3
wd:statement/Q4044834-6A9F1D0C-6EE1-403E-8752-9921EB331247
wd:statement/Q4044834-A9F115F3-CA27-40D4-BBAD-6199AE683CA6
wd:statement/Q4044834-AE2B72DA-6B5B-4AA1-B9E2-DC4F4458EAF4
wd:statement/Q4044834-B8BFC33D-9991-4E04-8545-5B39B5930CB2
wd:statement/Q4044834-C05A2E09-4BFE-466C-B981-DD24EB38EF0A
wd:statement/Q4044834-EF000F36-0B6F-477E-A0FB-DA8C214D7615
wd:statement/Q4044834-FC6E6EBE-1EAB-4494-A93E-00A930ECBEAA
p:P486 wd:statement/Q4044834-F9C88FB1-6185-42AF-9CF7-EFAE69A3ADFA
p:P527 wd:statement/Q4044834-18952108-FEFD-42DE-BFF1-D96452418873
wd:statement/Q4044834-1F07C7F4-BADF-4CB7-AFDA-A9AF5D4B8902
wd:statement/Q4044834-7150B7F5-B0D8-4DD2-BF95-BC40BA43204C
wd:statement/Q4044834-88C1E664-92CC-49D3-90B1-5939FF101251
wd:statement/Q4044834-BE9A956F-2B79-45E0-B4B7-0730FC9F71D5
wd:statement/Q4044834-BF12068C-CB7D-4F38-B3C2-97F10E9E96CE
wd:statement/Q4044834-CE952E1B-CB03-49C1-8478-219BD9391DD5
wd:statement/Q4044834-FCC1BC25-F318-4C27-B384-B7089884C7DC
p:P637 wd:statement/Q4044834-4047DFB2-68C3-45BA-AE11-28A53F3587C0
wd:statement/Q4044834-8CF4BEEA-D749-46AC-9115-425170EC266F
wd:statement/Q4044834-982824AE-6080-455A-A228-23035DB43F7D
wd:statement/Q4044834-A0AB5591-5D5A-4796-A537-49ECACEC84E3
wd:statement/Q4044834-B3C9977D-D6A5-49DD-8786-DDE93CF0CE1E
wd:statement/Q4044834-D8381F36-C1F8-4620-BE7A-9B6456C84D7D
wd:statement/Q4044834-EB83AC2A-84AB-4C94-9CC5-332F0CD978DF
wd:statement/Q4044834-F3D34186-CD97-48EA-8101-7BD767023E6B
wd:statement/Q4044834-F7AD0CB0-D007-46E0-ADE6-92CE69B858EA
p:P638 wd:statement/Q4044834-0EB01B7A-58E1-4010-8812-734C024543B7
wd:statement/Q4044834-1FC38C55-68FF-40C6-80FF-CEF6CD3F30D7
wd:statement/Q4044834-523C0F2B-CE85-4723-A010-30D56A57D533
wd:statement/Q4044834-5D0269BC-AF48-4D5B-BDF4-D87C8093A12F
wd:statement/Q4044834-60D01E0E-5D2B-4570-B2A6-4F79914A3401
wd:statement/Q4044834-65797B8E-4102-4BED-A36E-43A3291554EC
wd:statement/Q4044834-B3B23013-FE54-4A7C-9716-1D30100E5E2F
wd:statement/Q4044834-C79988E5-C4A0-4FE1-BC97-627D3FB5A9D8
p:P672 wd:statement/Q4044834-05a8fd73-47d8-295d-8907-5433c6fec527
wd:statement/Q4044834-1bfe38ce-4e3e-c897-116a-d76c8280f861
wd:statement/Q4044834-74afc479-4e6c-5a4e-a6e5-e3e3f5e02752
p:P680 wd:statement/Q4044834-0862652C-89A2-40D7-9B0A-51833D2AB127
wd:statement/Q4044834-0EE0083A-AE2C-4566-A9FB-5FDCC51B12BC
wd:statement/Q4044834-1CEC9545-67E1-4F3A-86C9-19C1D8313BAD
wd:statement/Q4044834-300CFE9A-FB7A-48D5-9DC6-77C9AAB89125
wd:statement/Q4044834-4129CF96-F740-499C-9B0C-102C70C0DA61
wd:statement/Q4044834-4287E248-7181-4603-888C-1C5E4F5BF3E8
wd:statement/Q4044834-61370E09-3A37-477B-AB28-7C6E2B9982F5
wd:statement/Q4044834-708A43AD-6929-491E-882A-BB4D4B308B0D
wd:statement/Q4044834-762B8307-4C88-4599-B0C0-3FEAA9B93CB3
wd:statement/Q4044834-7AEFF728-2400-471E-9FBA-1BD28A23C292
wd:statement/Q4044834-7D3B5A47-C422-432F-9B0C-33A98A251E0C
wd:statement/Q4044834-9E3C7B47-B1E0-4B69-A0A2-FDAD001C90CD
wd:statement/Q4044834-A612C725-57AE-44A6-A8FC-588895CFE641
wd:statement/Q4044834-BC2D8048-ED61-4C48-8648-7A527B8A2201
wd:statement/Q4044834-CF85EFC3-3FDF-4D65-82AB-2514EEF325AF
wd:statement/Q4044834-E66A67B8-F805-4BB3-AA6B-898498F5BA1C
wd:statement/Q4044834-E6E863F0-F9E3-4A72-B36E-A49197B72D28
p:P681 wd:statement/Q4044834-051760AB-DA8F-4F91-901D-194D821E02AA
wd:statement/Q4044834-38175343-AD73-4CCE-A28E-29DCDBB1110A
wd:statement/Q4044834-4E3B4D5D-347D-4D77-95A7-1B340A25DD2F
wd:statement/Q4044834-B5FE342D-26B2-466C-B395-99E61E1DE8ED
wd:statement/Q4044834-C49F2A15-B27B-4950-88F9-E620EE2C9CC8
wd:statement/Q4044834-C5BBD28B-DF10-4CE1-BD09-250C686BF7F2
wd:statement/Q4044834-D7A6E4E9-DC23-47C9-92DE-A29664C13E31
wd:statement/Q4044834-E751342C-6651-42F1-88D7-7CE1611BCD9F
wd:statement/Q4044834-EB9CE43B-798E-42B0-91EE-6A799D96A0D2
wd:statement/Q4044834-ECF15BE8-C15B-45A9-B89A-D3D76F066200
p:P682 wd:statement/Q4044834-029BA1F5-12D3-4EA8-9472-3682F0CCD171
wd:statement/Q4044834-05655137-CF46-4B09-BAAF-D0F2BE2A01E0
wd:statement/Q4044834-0823BB19-7272-4214-85C8-8B5D7CB7C143
wd:statement/Q4044834-0B628EEB-D8F7-4508-94B6-ECA77AB55734
wd:statement/Q4044834-12EB2A2D-62EB-4262-B1A0-F36D0E11A2F2
wd:statement/Q4044834-15468DC5-4A4D-4852-8E00-4595E1B0F960
wd:statement/Q4044834-2250747C-D990-40B3-A500-6F83C112EB2F
wd:statement/Q4044834-233F4645-C184-4351-96BE-575D05CC6B44
wd:statement/Q4044834-2376DC29-2342-490E-9D9F-FB08A2B54E76
wd:statement/Q4044834-3515DA2E-E6E1-4029-A2A9-CAD8433BD5A8
wd:statement/Q4044834-3C834F39-776D-407B-A2AA-9E27EA2E6E78
wd:statement/Q4044834-40C33814-0BD9-4C9D-B014-9A662054AD83
wd:statement/Q4044834-457199A4-18E0-4F19-8504-ECC082053A2E
wd:statement/Q4044834-4A5BFF6E-4BA5-49A0-BCA5-1BCF45C17A82
wd:statement/Q4044834-4D3E1572-E22E-486D-9C39-AD5AFC794776
wd:statement/Q4044834-4D9AF6E0-8B16-495D-836F-3F700DD6E582
wd:statement/Q4044834-4E0CE158-21FC-41D6-B02C-7C3C5D8C12B2
wd:statement/Q4044834-50C08D99-A263-475F-8162-38952CF3514D
wd:statement/Q4044834-517716C2-85F4-4E39-A336-F8661F41B21C
wd:statement/Q4044834-5307C87A-B3A6-4B81-A479-D6031D30B8AA
wd:statement/Q4044834-5EB6B438-6B03-4E28-AF96-7A46E061D85E
wd:statement/Q4044834-64EAA030-161B-4F3B-84F5-96868F38D5B2
wd:statement/Q4044834-76A901BF-DB28-4521-98FE-F871DDE673E9
wd:statement/Q4044834-77B9A14C-BF6F-4F61-8643-47F0B12657F6
wd:statement/Q4044834-78CD697F-92FA-43CD-B5F0-8C143FBDD709
wd:statement/Q4044834-8151AAB2-6CE5-4ADE-AA04-8B42F85351CB
wd:statement/Q4044834-8A930E14-7009-4704-9098-603E1474B66A
wd:statement/Q4044834-91109F17-202D-4DB5-9C07-ECA4BA9C432F
wd:statement/Q4044834-9217E7BB-3E46-42CD-926C-5C901DCF018D
wd:statement/Q4044834-93700772-56CF-4D22-A1D3-26862DCF9AB2
wd:statement/Q4044834-98FAD2B9-AA8D-47B7-9589-D6F9A84F681B
wd:statement/Q4044834-AE491007-B78C-4E27-871E-285B970BB8CC
wd:statement/Q4044834-AF372898-5255-4A2B-8786-C341BCCA34A3
wd:statement/Q4044834-B48426C8-9DD7-40A8-86E3-4BA7F1F1D6B9
wd:statement/Q4044834-C9F76443-AF80-4020-856F-095E25CCB43C
wd:statement/Q4044834-CADCC073-412A-4B36-B5ED-AB69F535DCC4
wd:statement/Q4044834-CB4DFD97-3B68-48C1-9980-694D8404ED0F
wd:statement/Q4044834-D051DD1C-30D0-4A7B-9B3E-45FF44BE048B
wd:statement/Q4044834-D564114C-98D0-47FE-936A-92226C934BE6
wd:statement/Q4044834-D8626FCB-BA3B-45C3-A7E3-369CC2CE39DB
wd:statement/Q4044834-E010CEE3-1997-4E72-AF94-4DA3AA6A1881
wd:statement/Q4044834-E5FEC70E-EDB9-44D7-A57F-D2DB59C7F140
wd:statement/Q4044834-F53A7DEA-B32E-41B8-B55C-08039F68491E
wd:statement/Q4044834-FBFA16F1-D521-4A5B-BEB3-13983AC8D198
p:P702 wd:statement/Q4044834-2FA24DBA-95E6-42F5-A7EC-30E894304350
p:P703 wd:statement/Q4044834-1EE74D44-1702-47CF-A732-FEF1639D9FBB
p:P705 wd:statement/Q4044834-1CB4F2CC-BEFC-4655-8A13-8DE52DBBCCB1
wd:statement/Q4044834-2B0C5CA8-E820-460D-BABF-9294888A394A
wd:statement/Q4044834-47556559-8606-40EE-A1F2-9153918C5E30
wd:statement/Q4044834-52AC565E-83FE-4142-9796-4E8C5D65A143
wd:statement/Q4044834-664D9C0A-661C-462C-949B-259C964102D6
wd:statement/Q4044834-874AE167-3309-4792-A58E-A1C5A289B7E4
wd:statement/Q4044834-94C69BAD-FEA6-40EC-880D-640B9F966FDA
wd:statement/Q4044834-BC447964-FCBE-4BCD-8BE7-DE30F20D5D71
wd:statement/Q4044834-BF1900E9-287E-461C-91FF-FE559E93CC89
wd:statement/Q4044834-C34E83E7-08EB-4A0E-A6EB-ED7F39654F12
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P19838>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D052002>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_001158884>
<http://purl.uniprot.org/refseq/NP_001306155>
<http://purl.uniprot.org/refseq/NP_001369554>
<http://purl.uniprot.org/refseq/NP_001369555>
<http://purl.uniprot.org/refseq/NP_001369556>
<http://purl.uniprot.org/refseq/NP_001369557>
<http://purl.uniprot.org/refseq/NP_003989>
<http://purl.uniprot.org/refseq/XP_024309836>
<http://purl.uniprot.org/refseq/XP_024309837>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1MDI>
<https://rdf.wwpdb.org/pdb/1MDJ>
<https://rdf.wwpdb.org/pdb/1MDK>
<https://rdf.wwpdb.org/pdb/1NFI>
<https://rdf.wwpdb.org/pdb/1SVC>
<https://rdf.wwpdb.org/pdb/2DBF>
<https://rdf.wwpdb.org/pdb/2O61>
<https://rdf.wwpdb.org/pdb/3GUT>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D12.776.260.600.124>
<http://id.nlm.nih.gov/mesh/D12.776.660.600.124>
<http://id.nlm.nih.gov/mesh/D12.776.930.600.124>
wdt:P2892 "C0132348"
wdt:P31 protein
wdt:P352 "P19838"
wdt:P361 Nuclear factor NF-kappa-B, p105 subunit
p53-like transcription factor, DNA-binding
Death-like domain superfamily
Immunoglobulin E-set
Immunoglobulin-like fold
Ankyrin repeat-containing domain superfamily
Rel homology domain (RHD), DNA-binding domain superfamily
Death domain, protein family
Rel homology domain (RHD), DNA-binding domain, protein family
IPT domain, protein family
Rel homology dimerisation domain, protein family
Ankyrin repeat-containing domain, protein family
NFkappaB IPT domain, protein family
Rel homology domain, conserved site, protein family
Ankyrin repeat, protein family
wdt:P486 "D052002"
wdt:P527 Rel homology domain (RHD), DNA-binding domain
Rel homology domain, conserved site
IPT domain
Rel homology dimerisation domain
ankyrin repeat-containing domain
ankyrin repeat
NFkappaB IPT domain
death domain
wdt:P637 "NP_001158884"
"NP_001306155"
"NP_001369554"
"NP_001369555"
"NP_001369556"
"NP_001369557"
"NP_003989"
"XP_024309836"
"XP_024309837"
wdt:P638 "1MDI"
"1MDJ"
"1MDK"
"1NFI"
"1SVC"
"2DBF"
"2O61"
"3GUT"
wdt:P672 "D12.776.260.600.124"
"D12.776.660.600.124"
"D12.776.930.600.124"
wdt:P680 DNA binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
DNA-binding transcription activator activity, RNA polymerase II-specific
chromatin binding
DNA-binding transcription factor activity
transcription factor binding
sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
transcription cis-regulatory region binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
actinin binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
protein binding
DNA-binding transcription repressor activity, RNA polymerase II-specific
wdt:P681 extracellular region
secretory granule lumen
nucleoplasm
I-kappaB/NF-kappaB complex
cytosol
specific granule lumen
mitochondrion
nucleus
cytoplasm
wdt:P682 apoptotic process
negative regulation of apoptotic process
negative regulation of calcidiol 1-monooxygenase activity
negative regulation of transcription by RNA polymerase II
regulation of transcription, DNA-templated
negative regulation of transcription, DNA-templated
positive regulation of NF-kappaB transcription factor activity
transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
cellular response to interleukin-1
inflammatory response
negative regulation of gene expression
regulation of transcription by RNA polymerase II
positive regulation of macrophage derived foam cell differentiation
stress-activated MAPK cascade
cellular response to mechanical stimulus
positive regulation of canonical Wnt signaling pathway
negative regulation of inflammatory response
cellular response to lipopolysaccharide
T cell receptor signaling pathway
negative regulation of cytokine production
transcription by RNA polymerase II
positive regulation of hyaluronan biosynthetic process
interleukin-1-mediated signaling pathway
cellular response to interleukin-6
positive regulation of type I interferon production
Fc-epsilon receptor signaling pathway
positive regulation of lipid storage
cellular response to tumor necrosis factor
positive regulation of miRNA metabolic process
cellular response to nicotine
membrane protein intracellular domain proteolysis
negative regulation of cholesterol transport
neutrophil degranulation
cellular response to dsRNA
negative regulation of vitamin D biosynthetic process
I-kappaB kinase/NF-kappaB signaling
stimulatory C-type lectin receptor signaling pathway
response to muscle stretch
NIK/NF-kappaB signaling
cellular response to angiotensin
innate immune response
signal transduction
wdt:P702 NFKB1
wdt:P703 man
wdt:P705 "ENSP00000226574"
"ENSP00000378297"
"ENSP00000420904"
"ENSP00000423877"
"ENSP00000424790"
"ENSP00000424815"
"ENSP00000426147"
"ENSP00000469340"
"ENSP00000498904"
"ENSP00000499031"
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data from SPARQL profile: Wikidata