SHMARQL

tacrolimus

<http://www.wikidata.org/entity/Q411648>

immunosuppressive Rx drug
rdfs:label
"tacrolimus"@en
skos:altLabel
"(-)-FK 506"@en
"FK506"@en
"anhydrous tacrolimus"@en
"fujimycin"@en
"tacrolimus anhydrous"@en
schema:description
"immunosuppressive Rx drug"@en
schema:dateModified "2026-11-10T21:17:57+00:00"^^xsd:dateTime
schema:version 2567700904
wikibase:identifiers 75
wikibase:sitelinks 34
wikibase:statements 197
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p:direct-normalized/P665 <http://www.kegg.jp/entry/C01375>
<http://www.kegg.jp/entry/D08556>
p:direct-normalized/P6694 <http://id.nlm.nih.gov/mesh/M0329463>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D02.540.505.810>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_61049>
p:direct-normalized/P8408 <http://kbpedia.org/kko/rc/Tacrolimus>
wdt:P10245 "a601117"
"a602020"
"a608037"
wdt:P10283 "C2909675724"
wdt:P11089 "184250"
wdt:P11143 "Tacrolimus"
wdt:P11199 "PD003361"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Tacrolimus-2D-skeletal.png>
wdt:P129 FKBP prolyl isomerase 1A
wdt:P1417 "topic/tacrolimus"
wdt:P1579 "3647477"
"8821611"
wdt:P176 Pfizer
wdt:P2004 "131695"
wdt:P2017 "C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC"
wdt:P2062 "8195"
wdt:P2063 "LMPK04000003"
wdt:P2067 803.482^^xsd:decimal
wdt:P2115 "N0000148372"
wdt:P2175 interstitial lung disease
graft-versus-host disease
ulcerative colitis
lupus nephritis
conjunctivitis
vitiligo
atopic dermatitis
nephrotic syndrome
acute graft versus host disease
autoimmune hepatitis
myasthenia gravis
lichen planus
polymyositis
wdt:P2275
"tacrolimus"@en
wdt:P231 "104987-11-3"
wdt:P232 "627-021-3"
wdt:P233 "CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC"
wdt:P234 "InChI=1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19+,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1"
wdt:P2347 "23272"
wdt:P235 "QJJXYPPXXYFBGM-LFZNUXCKSA-N"
wdt:P244 "sh94005977"
wdt:P2566 "100.155.367"
wdt:P267 "D11AH01"
"L04AD02"
wdt:P274 "C₄₄H₆₉NO₁₂"
wdt:P279 macrolides
alkaloid
wdt:P2868 immunosuppressive drug
enzyme inhibitor
wdt:P2877 "3088"
wdt:P2892 "C0085149"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID5046354"
wdt:P3345 "235991"
"42316"
wdt:P3364 wd:Q108730784
LSM-3557
LSM-5735
wd:Q63398962
wdt:P3489 US pregnancy category C
Australian pregnancy category C
wdt:P3493 boxed warning
wdt:P361 FK506 binding
wdt:P3636 "FK5"
wdt:P366 medication
chemical probe
wdt:P373 "Tacrolimus"
wdt:P4235 "tacrolimus"
wdt:P4250 5.0^^xsd:decimal
wdt:P4802 "109981"
wdt:P486 "D016559"
wdt:P5082 "takrolimus"
wdt:P592 "CHEMBL269732"
wdt:P595 "6784"
wdt:P636 oral administration
intravenous infusion and defusion
wdt:P638 "1BKF"
"1FKF"
"1FKJ"
"1Q6I"
"1TCO"
"1YAT"
"2FKE"
"2VN1"
"3IHZ"
"3O5R"
"3UF8"
"3UQA"
"3UQB"
"3VAW"
"4DZ2"
"4DZ3"
"4LAX"
"4NNR"
"4ODO"
"4ODR"
"5B8I"
"5D75"
"5HUA"
"5HW8"
"5HWC"
wdt:P646 "/m/014_0n"
wdt:P652 "Y5L2157C4J"
wdt:P661 "393220"
wdt:P662 "445643"
wdt:P665 "C01375"
"D08556"
wdt:P6694 "M0329463"
wdt:P672 "D02.540.505.810"
wdt:P680 FK506 binding
wdt:P683 "61049"
wdt:P703 Streptomyces tacrolimicus
Streptomyces hygroscopicus
Streptomyces clavuligerus
Penicillium
wdt:P715 "DB00864"
wdt:P7524 "tacrolimus"
wdt:P769 clarithromycin
naproxen
ibuprofen
erythromycin
Diclofenac
(RS)-etodolac
(RS)-fenoprofen
parecoxib
cyclosporine
ketoconazole
dronedarone
piroxicam
celecoxib
(RS)-ketoprofen
indomethacin
amiodarone
itraconazole
fluconazole
voriconazole
meloxicam
pentamidine
ganciclovir
(±)-flurbiprofen
foscarnet
ritonavir
saquinavir
valganciclovir
atazanavir
nabumetone
tenoxicam
aceclofenac
crizotinib
fosphenytoin
ranolazine
sulindac
wdt:P8189 "987007549156305171"
wdt:P8408 "Tacrolimus"
wdt:P8494 "DTXCID3026354"
wdt:P8669 "tacrolimus"
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