SHMARQL

CD4 molecule

<http://www.wikidata.org/entity/Q412587>

mammalian protein found in Homo sapiens
rdfs:label
"CD4 molecule"@en
skos:altLabel
"CD4"@en
"CD4 Antigens"@en
"CD4 antigen (p55)"@en
"CD4 protein"@en
"CD4 receptor"@en
"T-cell surface antigen T4/Leu-3"@en
"T-cell surface glycoprotein CD4"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-03-16T02:47:00+00:00"^^xsd:dateTime
schema:version 2472353489
wikibase:identifiers 67
wikibase:sitelinks 25
wikibase:statements 172
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wd:statement/Q412587-CFC09162-CCF9-43A9-8CDD-811264572FAE
p:P638 wd:statement/Q412587-08FCAD38-38BF-4677-9F26-B40257F80B6A
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p:P680 wd:statement/Q412587-0AD2E0CC-72E8-45DF-9961-183C25C5497E
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p:P681 wd:statement/Q412587-0336551E-687D-400C-B5FF-5358EB59B9EB
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p:P682 wd:statement/Q412587-03187834-DA27-4F37-A1B9-26D365749E51
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wd:statement/Q412587-E67F34A1-AB10-41B7-962F-C432A69D93CD
wd:statement/Q412587-E715F4C6-6C41-44EA-BD48-F6E1ECB56AB2
wd:statement/Q412587-EDE13BD1-3E17-4F7D-BEA4-B80C1B2F0A11
p:P692 wd:statement/Q412587-BEAF021D-834B-4195-B4F1-F48984B62726
p:P702 wd:statement/Q412587-DCB1CA0B-0A5D-425F-BF0E-EC9D8488BD09
p:P703 wd:statement/Q412587-E1F1B973-D6B7-4806-8703-D8885493F52D
p:P705 wd:statement/Q412587-348F0258-EF42-4A90-96C5-71CA39BB65A0
wd:statement/Q412587-EA680346-317E-4BF0-8EBD-EF52F2CAFE81
wd:statement/q412587-03185A7B-196A-4B06-AB0C-EF1FF84583DE
p:P7260 wd:statement/Q412587-E3648BFF-4598-4787-891A-384CCC9B36B5
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P01730>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_000607>
<http://purl.uniprot.org/refseq/NP_001181943>
<http://purl.uniprot.org/refseq/NP_001181944>
<http://purl.uniprot.org/refseq/NP_001181945>
<http://purl.uniprot.org/refseq/NP_001181946>
<http://purl.uniprot.org/refseq/NP_001369634>
<http://purl.uniprot.org/refseq/NP_001369635>
<http://purl.uniprot.org/refseq/NP_001369636>
<http://purl.uniprot.org/refseq/NP_001369643>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1CDH>
<https://rdf.wwpdb.org/pdb/1CDI>
<https://rdf.wwpdb.org/pdb/1CDJ>
<https://rdf.wwpdb.org/pdb/1CDU>
<https://rdf.wwpdb.org/pdb/1CDY>
<https://rdf.wwpdb.org/pdb/1G9M>
<https://rdf.wwpdb.org/pdb/1G9N>
<https://rdf.wwpdb.org/pdb/1GC1>
<https://rdf.wwpdb.org/pdb/1JL4>
<https://rdf.wwpdb.org/pdb/1Q68>
<https://rdf.wwpdb.org/pdb/1RZJ>
<https://rdf.wwpdb.org/pdb/1RZK>
<https://rdf.wwpdb.org/pdb/1WBR>
<https://rdf.wwpdb.org/pdb/1WIO>
<https://rdf.wwpdb.org/pdb/1WIP>
<https://rdf.wwpdb.org/pdb/1WIQ>
<https://rdf.wwpdb.org/pdb/2B4C>
<https://rdf.wwpdb.org/pdb/2JKR>
<https://rdf.wwpdb.org/pdb/2JKT>
<https://rdf.wwpdb.org/pdb/2KLU>
<https://rdf.wwpdb.org/pdb/2NXY>
<https://rdf.wwpdb.org/pdb/2NXZ>
<https://rdf.wwpdb.org/pdb/2NY0>
<https://rdf.wwpdb.org/pdb/2NY1>
<https://rdf.wwpdb.org/pdb/2NY2>
<https://rdf.wwpdb.org/pdb/2NY3>
<https://rdf.wwpdb.org/pdb/2NY4>
<https://rdf.wwpdb.org/pdb/2NY5>
<https://rdf.wwpdb.org/pdb/2NY6>
<https://rdf.wwpdb.org/pdb/2QAD>
<https://rdf.wwpdb.org/pdb/3B71>
<https://rdf.wwpdb.org/pdb/3CD4>
<https://rdf.wwpdb.org/pdb/3J70>
<https://rdf.wwpdb.org/pdb/3JWD>
<https://rdf.wwpdb.org/pdb/3JWO>
<https://rdf.wwpdb.org/pdb/3LQA>
<https://rdf.wwpdb.org/pdb/3O2D>
<https://rdf.wwpdb.org/pdb/3S4S>
<https://rdf.wwpdb.org/pdb/3S5L>
<https://rdf.wwpdb.org/pdb/3T0E>
<https://rdf.wwpdb.org/pdb/4H8W>
<https://rdf.wwpdb.org/pdb/4JM2>
<https://rdf.wwpdb.org/pdb/4P9H>
<https://rdf.wwpdb.org/pdb/4Q6I>
<https://rdf.wwpdb.org/pdb/4R2G>
<https://rdf.wwpdb.org/pdb/4R4H>
<https://rdf.wwpdb.org/pdb/4RQS>
<https://rdf.wwpdb.org/pdb/5A7X>
<https://rdf.wwpdb.org/pdb/5A8H>
<https://rdf.wwpdb.org/pdb/5CAY>
wdt:P2888 <http://purl.uniprot.org/uniprot/P01730>
wdt:P2892 "C0003323"
wdt:P2910 <http://commons.wikimedia.org/wiki/Special:FilePath/Schematic%20CD4%20Protein%20%28NIH%20BioArt%20466%20-%20635022%29.svg>
wdt:P31 protein
wdt:P352 "P01730"
wdt:P361 T-cell surface antigen CD4
Immunoglobulin-like fold
Immunoglobulin-like domain superfamily
T cell CD4 receptor C-terminal region, protein family
Immunoglobulin C2-set, protein family
Immunoglobulin domain, protein family
Immunoglobulin subtype 2, protein family
CD4, extracellular domain, protein family
immunoglobulin-like domain, protein family
Immunoglobulin V-set domain, protein family
immunoglobulin subtype, protein family
wdt:P373 "CD4"
wdt:P527 T cell CD4 receptor C-terminal region
Immunoglobulin C2-set
immunoglobulin domain
immunoglobulin subtype 2
CD4, extracellular
immunoglobulin-like domain
immunoglobulin V-set domain
immunoglobulin subtype
wdt:P637 "NP_000607"
"NP_001181943"
"NP_001181944"
"NP_001181945"
"NP_001181946"
"NP_001369634"
"NP_001369635"
"NP_001369636"
"NP_001369643"
wdt:P638 "1CDH"
"1CDI"
"1CDJ"
"1CDU"
"1CDY"
"1G9M"
"1G9N"
"1GC1"
"1JL4"
"1Q68"
"1RZJ"
"1RZK"
"1WBR"
"1WIO"
"1WIP"
"1WIQ"
"2B4C"
"2JKR"
"2JKT"
"2KLU"
"2NXY"
"2NXZ"
"2NY0"
"2NY1"
"2NY2"
"2NY3"
"2NY4"
"2NY5"
"2NY6"
"2QAD"
"3B71"
"3CD4"
"3J70"
"3JWD"
"3JWO"
"3LQA"
"3O2D"
"3S4S"
"3S5L"
"3T0E"
"4H8W"
"4JM2"
"4P9H"
"4Q6I"
"4R2G"
"4R4H"
"4RQS"
"5A7X"
"5A8H"
"5CAY"
wdt:P646 "/m/02kfly8"
"/m/063m46"
wdt:P680 enzyme binding
zinc ion binding
identical protein binding
protein homodimerization activity
protein kinase binding
signaling receptor binding
extracellular matrix structural constituent
immunoglobulin binding
MHC class II protein binding
transmembrane signaling receptor activity
coreceptor activity
virus receptor activity
protein binding
signaling receptor activity
protein tyrosine kinase binding
interleukin-16 binding
interleukin-16 receptor activity
wdt:P681 integral component of membrane
endoplasmic reticulum membrane
membrane
endoplasmic reticulum lumen
external side of plasma membrane
integral component of plasma membrane
early endosome
T cell receptor complex
cell surface
clathrin-coated vesicle membrane
plasma membrane
membrane raft
wdt:P682 positive regulation of protein kinase activity
positive regulation of peptidyl-tyrosine phosphorylation
response to vitamin D
response to estradiol
positive regulation of MAPK cascade
positive regulation of transcription, DNA-templated
positive regulation of protein phosphorylation
cell surface receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade
regulation of calcium ion transport
cytokine-mediated signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
T cell differentiation
T cell activation
T cell receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of T cell proliferation
positive regulation of calcium-mediated signaling
positive regulation of T cell activation
viral process
defense response to Gram-negative bacterium
cytokine production
induction by virus of host cell-cell fusion
enzyme linked receptor protein signaling pathway
maintenance of protein location in cell
T cell selection
mitigation of host defenses by virus
regulation of T cell activation
positive regulation of kinase activity
membrane organization
adaptive immune response
macrophage differentiation
positive regulation of monocyte differentiation
positive regulation of calcium ion transport into cytosol
immune system process
immune response
cell adhesion
cellular response to granulocyte macrophage colony-stimulating factor stimulus
fusion of virus membrane with host plasma membrane
positive regulation of viral entry into host cell
interleukin-15-mediated signaling pathway
helper T cell enhancement of adaptive immune response
signal transduction
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20CD4%20203547%20at%20fs.png>
wdt:P702 CD4
wdt:P703 man
wdt:P705 "ENSP00000011653"
"ENSP00000440720"
"ENSP00000445167"
wdt:P7260 "8.A.23.2.1"
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