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rdfs:label
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"ERBB2"@cy
"ERBB2"@uk
"ERBB2"@bs
"Erb-b2 receptor tyrosine kinase 2"@en
"HER-2/neu"@vi
"HER2"@ja
"HER2"@ru
"HER2"@fr
"HER2"@ko
"HER2"@fi
"HER2/neu"@fa
"HER2/neu"@he
"HER2/neu"@it
"HER2/neu"@sh
"HER2/neu"@sr
"HER2/neu"@ca
"HER2/neu"@de
"HER2/neu"@de-ch
"HER2/neu"@en-ca
"HER2/neu"@en-gb
"HER2/neu"@es
"HER2/neu"@gl
"HER2/neu"@nl
"HER2/neu"@pt
"HER2/neu"@pt-br
"HER2/neu"@sl
"مستقبل عامل نمو البشري الثاني"@ar
"人类表皮生长因子受体II"@zh
"人类表皮生长因子受体II"@zh-cn
"人类表皮生长因子受体II"@zh-hans
"人类表皮生长因子受体II"@zh-sg
"人類表皮生長因子受體II"@zh-hant
"人類表皮生長因子受體II"@zh-hk
"人類表皮生長因子受體II"@zh-tw
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skos:altLabel
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"CD340"@es
"CD340"@it
"CD340"@ru
"EGFR2"@ja
"ERBB2"@en
"ERBB2"@ja
"ERb-b2 receptorska tirozin kinaza"@sl
"ErbB-2"@de
"ErbB-2"@fr
"ErbB-2"@he
"ErbB-2"@ru
"ErbB2"@es
"ErbB2"@fr
"ErbB2"@pt
"ErbB2"@ru
"HER-2"@he
"HER2"@de
"HER2"@es
"HER2"@nl
"HER2"@pt
"HER2"@he
"HER2/neu"@ja
"Human epidermal growth factor receptor 2"@pt
"MLN 19"@en
"P185"@es
"Receptor, ErbB-2"@en
"Recettore erbB-2"@it
"c-erb B2/neu protein"@en
"herstatin"@en
"human epidermal growth factor receptor 2"@en
"metastatic lymph node gene 19 protein"@en
"neuro/glioblastoma derived oncogene homolog"@en
"neuroblastoma/glioblastoma derived oncogene homolog"@en
"p185erbB2"@en
"proto-oncogene Neu"@en
"proto-oncogene c-ErbB-2"@en
"receptor epidermalnega rastnega faktorja 2"@sl
"receptor tyrosine-protein kinase erbB-2"@en
"tyrosine kinase-type cell surface receptor HER2"@en
"v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2"@en
"v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2"@en
"v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog"@en
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schema:description
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"Protein"@de
"mammalian protein found in Homo sapiens"@en
"menselijk eiwit"@nl
"neu(-)"@ru
"protein"@sv
"protein"@id
"proteinë"@sq
"proteína mamífera encontrada en humanos"@es
"protèin"@ace
"protéine humaine"@fr
"sesalski protein pri vrsti Homo sapiens"@sl
"білок людини"@uk
"חלבון המקודד על ידי הגן ERBB2"@he
"بروتين في الإنسان العاقل"@ar
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schema:dateModified
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"2026-10-11T13:33:57+00:00"^^xsd:dateTime
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schema:version
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2555886266
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wikibase:identifiers
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84
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wikibase:sitelinks
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wd:statement/Q415271-23F56E40-92E4-458C-A726-331D541C93F8
|
|
wd:statement/Q415271-287D5A44-A0C3-4E92-AA41-13E18E0B1A2A
|
|
wd:statement/Q415271-2C224360-4EFD-4FA0-A810-176C2435ADA1
|
|
wd:statement/Q415271-2E43E095-D5BD-42D2-B5A4-61240D19084E
|
|
wd:statement/Q415271-3B9ACD64-A0D5-4402-9F49-19C3D33C7D73
|
|
wd:statement/Q415271-3E54E68F-0468-4DF5-82BA-D2F4A2712AA7
|
|
wd:statement/Q415271-43F791DB-6138-4735-87B9-A743984CC416
|
|
wd:statement/Q415271-49A25579-A33E-4481-B3A2-5A40F9F1CD4F
|
|
wd:statement/Q415271-4CFA45FE-932A-49A2-8233-740B8EAEF25C
|
|
wd:statement/Q415271-5DA93B21-B30D-4C8B-942C-2A3DF18F2AED
|
|
wd:statement/Q415271-64AF3666-7672-4BAC-9FB9-036936F04758
|
|
wd:statement/Q415271-6686AF58-4753-4539-AFF4-DA04EE93E233
|
|
wd:statement/Q415271-73E96DD7-E970-49F4-ABFF-7C784403B9FA
|
|
wd:statement/Q415271-74294480-46E3-49BE-9420-B88860ED66AA
|
|
wd:statement/Q415271-7979BD04-6093-476C-8482-2A1A374BF14B
|
|
wd:statement/Q415271-7B3997EC-18CC-4BBB-BF12-591D4EB199D9
|
|
wd:statement/Q415271-7FE84C47-0742-42FC-BAF8-72158C029760
|
|
wd:statement/Q415271-81E714C5-570F-44A1-832F-650700A49A66
|
|
wd:statement/Q415271-8A457D1F-CDF7-48C2-A81B-7E670A07468C
|
|
wd:statement/Q415271-8CF91B88-57B7-4E96-976A-A699FA0ED0C4
|
|
wd:statement/Q415271-93F522B3-2CFD-409C-BC4A-16A696999BB5
|
|
wd:statement/Q415271-96FCB557-FF1D-4F15-9C4E-945EF793DCFC
|
|
wd:statement/Q415271-9E88AAF2-8B9F-4B7D-AE7B-EAB9FF1B5870
|
|
wd:statement/Q415271-9F4ED733-31E8-44A3-B85F-D221E073591A
|
|
wd:statement/Q415271-A0F61823-559B-45BF-BE92-C6D2BE88EAD4
|
|
wd:statement/Q415271-A12A5538-2369-4E31-918F-D4A1CFD33E9D
|
|
wd:statement/Q415271-AF0D29CE-3C83-4971-883F-732C6D34C539
|
|
wd:statement/Q415271-B2C2A338-15DD-4749-A334-1277502308ED
|
|
wd:statement/Q415271-B39EEFA8-E006-488F-977F-2D1F3038AFCC
|
|
wd:statement/Q415271-B924A643-C9BC-4DF0-A29B-74BA8FA1270D
|
|
wd:statement/Q415271-C1AAD25E-3CD0-4A03-B20B-7980C7343991
|
|
wd:statement/Q415271-C689898A-24B1-4796-B9F8-0DF4D3603F7B
|
|
wd:statement/Q415271-D32B0CE5-70EB-44AA-92E5-B875E884BC23
|
|
wd:statement/Q415271-D8BA2F96-43A3-4411-8DD0-7154D738559C
|
|
wd:statement/Q415271-D9875A5D-1A64-4739-ADED-6BDFC16510C7
|
|
wd:statement/Q415271-E13D8936-28BE-40E9-802A-AE3D53CEFBA8
|
|
wd:statement/Q415271-E4E31A8C-42BE-44FF-B35B-B3E2167EA544
|
|
wd:statement/Q415271-F303C5BA-E22D-4E84-BA22-E2863D6CB290
|
|
wd:statement/Q415271-F4357073-8B49-42C1-95D4-A780250651E8
|
|
wd:statement/Q415271-F61F9B3D-E446-49ED-832F-B631973062AC
|
|
wd:statement/Q415271-F6FB5407-66AB-4D37-8281-0A7B0E5A5930
|
|
p:P692
|
wd:statement/Q415271-9CB4C1F9-F6E4-4ED9-8FDB-95A231CD80F9
|
|
p:P702
|
wd:statement/q415271-A4DFC7A7-1C7D-4E11-B454-2F67D48969F7
|
|
p:P703
|
wd:statement/Q415271-EBBB6EA6-E646-4F76-901F-9E122B012E51
|
|
p:P705
|
wd:statement/Q415271-0F2D352F-0403-43EB-8F17-C8877FF90B29
|
|
wd:statement/Q415271-5332D2BA-2F15-47B3-86EC-889959570AF5
|
|
wd:statement/Q415271-541D0017-41EC-46D8-AB47-0BE5052F6824
|
|
wd:statement/Q415271-55FF3A55-1A74-4718-ABDC-7C68B3119F73
|
|
wd:statement/Q415271-6EEC9FAE-3E81-407A-AD70-E6CB6FC1242C
|
|
wd:statement/Q415271-D08CF70A-2C21-4879-9FC3-81230AA93D0A
|
|
wd:statement/Q415271-D54615E7-AD42-43AB-9E10-101AD98E76DD
|
|
wd:statement/Q415271-E5CB2AA3-F344-4CB7-BB86-1CE073CCA53C
|
|
wd:statement/Q415271-FDD02269-6344-417E-908A-DA067E577E3E
|
|
wd:statement/q415271-3D7F40ED-9B92-40D7-94A5-FF9B8A40211B
|
|
wd:statement/q415271-8E8919D7-57B8-44D6-BA29-F9FB988074CE
|
|
wd:statement/q415271-BBB02FCF-5580-49B9-A2EE-13FF109571B3
|
|
wd:statement/q415271-F5D5C296-015D-4240-8E2F-5B55DBCB6CF4
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P04626>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/D018719>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/2776872082>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001005862>
|
|
<http://purl.uniprot.org/refseq/NP_001276865>
|
|
<http://purl.uniprot.org/refseq/NP_001276866>
|
|
<http://purl.uniprot.org/refseq/NP_001276867>
|
|
<http://purl.uniprot.org/refseq/NP_001369711>
|
|
<http://purl.uniprot.org/refseq/NP_001369712>
|
|
<http://purl.uniprot.org/refseq/NP_001369713>
|
|
<http://purl.uniprot.org/refseq/NP_001369714>
|
|
<http://purl.uniprot.org/refseq/NP_001369715>
|
|
<http://purl.uniprot.org/refseq/NP_001369716>
|
|
<http://purl.uniprot.org/refseq/NP_001369717>
|
|
<http://purl.uniprot.org/refseq/NP_001369718>
|
|
<http://purl.uniprot.org/refseq/NP_001369719>
|
|
<http://purl.uniprot.org/refseq/NP_001369720>
|
|
<http://purl.uniprot.org/refseq/NP_001369721>
|
|
<http://purl.uniprot.org/refseq/NP_001369722>
|
|
<http://purl.uniprot.org/refseq/NP_001369723>
|
|
<http://purl.uniprot.org/refseq/NP_001369724>
|
|
<http://purl.uniprot.org/refseq/NP_001369725>
|
|
<http://purl.uniprot.org/refseq/NP_001369726>
|
|
<http://purl.uniprot.org/refseq/NP_001369727>
|
|
<http://purl.uniprot.org/refseq/NP_001369728>
|
|
<http://purl.uniprot.org/refseq/NP_001369729>
|
|
<http://purl.uniprot.org/refseq/NP_001369730>
|
|
<http://purl.uniprot.org/refseq/NP_001369731>
|
|
<http://purl.uniprot.org/refseq/NP_001369732>
|
|
<http://purl.uniprot.org/refseq/NP_001369733>
|
|
<http://purl.uniprot.org/refseq/NP_001369734>
|
|
<http://purl.uniprot.org/refseq/NP_001369735>
|
|
<http://purl.uniprot.org/refseq/NP_004439>
|
|
<http://purl.uniprot.org/refseq/XP_024306409>
|
|
<http://purl.uniprot.org/refseq/XP_024306410>
|
|
<http://purl.uniprot.org/refseq/XP_024306411>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1MFG>
|
|
<https://rdf.wwpdb.org/pdb/1MFL>
|
|
<https://rdf.wwpdb.org/pdb/1MW4>
|
|
<https://rdf.wwpdb.org/pdb/1N8Z>
|
|
<https://rdf.wwpdb.org/pdb/1QR1>
|
|
<https://rdf.wwpdb.org/pdb/1S78>
|
|
<https://rdf.wwpdb.org/pdb/2A91>
|
|
<https://rdf.wwpdb.org/pdb/2JWA>
|
|
<https://rdf.wwpdb.org/pdb/2KS1>
|
|
<https://rdf.wwpdb.org/pdb/2L4K>
|
|
<https://rdf.wwpdb.org/pdb/2N2A>
|
|
<https://rdf.wwpdb.org/pdb/3BE1>
|
|
<https://rdf.wwpdb.org/pdb/3H3B>
|
|
<https://rdf.wwpdb.org/pdb/3MZW>
|
|
<https://rdf.wwpdb.org/pdb/3N85>
|
|
<https://rdf.wwpdb.org/pdb/3PP0>
|
|
<https://rdf.wwpdb.org/pdb/3RCD>
|
|
<https://rdf.wwpdb.org/pdb/3WLW>
|
|
<https://rdf.wwpdb.org/pdb/3WSQ>
|
|
<https://rdf.wwpdb.org/pdb/4GFU>
|
|
<https://rdf.wwpdb.org/pdb/4HRL>
|
|
<https://rdf.wwpdb.org/pdb/4HRM>
|
|
<https://rdf.wwpdb.org/pdb/4HRN>
|
|
p:direct-normalized/P672
|
<http://id.nlm.nih.gov/mesh/D08.811.913.696.620.682.725.400.009.400>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.476.568.400.009.400>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.543.750.630.009.400>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.543.750.750.400.074.400>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.624.664.700.642>
|
|
<http://id.nlm.nih.gov/mesh/D23.050.301.500.600.700>
|
|
<http://id.nlm.nih.gov/mesh/D23.050.705.552.600.550>
|
|
<http://id.nlm.nih.gov/mesh/D23.101.140.642>
|
|
wdt:P10283
|
"C2908728163"
|
|
wdt:P129
|
Margetuximab
|
|
dacomitinib
|
|
pertuzumab
|
|
tucatinib
|
|
bms-599626
|
|
bms-690514
|
|
cp-724714
|
|
cudc-101
|
|
poziotinib
|
|
sapitinib
|
|
varlitinib
|
|
tesevatinib
|
|
lapatinib
|
|
afatinib
|
|
canertinib
|
|
mubritinib
|
|
neratinib
|
|
wdt:P13204
|
"qur8tv43"
|
|
wdt:P2888
|
<http://purl.uniprot.org/uniprot/P04626>
|
|
wdt:P2892
|
"C0069515"
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P04626"
|
|
wdt:P361
|
Tyrosine protein kinase, EGF/ERB/XmrK receptor
|
|
Growth factor receptor cysteine-rich domain superfamily
|
|
Protein kinase-like domain superfamily
|
|
Receptor L-domain superfamily
|
|
Tyrosine-protein kinase, catalytic domain, protein family
|
|
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
|
|
Protein kinase domain, protein family
|
|
Growth factor receptor domain 4, protein family
|
|
Receptor L-domain, protein family
|
|
Furin-like cysteine-rich domain, protein family
|
|
Furin-like repeat, protein family
|
|
Tyrosine-protein kinase, active site, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P373
|
"ErbB-2 receptor"
|
|
wdt:P486
|
"D018719"
|
|
wdt:P527
|
tyrosine-protein kinase, catalytic domain
|
|
tyrosine-protein kinase, active site
|
|
serine-threonine/tyrosine-protein kinase, catalytic domain
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
Furin-like repeat
|
|
Receptor L-domain
|
|
Growth factor receptor domain 4
|
|
Furin-like cysteine-rich domain
|
|
wdt:P591
|
"2.7.10.1"
|
|
wdt:P6366
|
"2776872082"
|
|
wdt:P637
|
"NP_001005862"
|
|
"NP_001276865"
|
|
"NP_001276866"
|
|
"NP_001276867"
|
|
"NP_001369711"
|
|
"NP_001369712"
|
|
"NP_001369713"
|
|
"NP_001369714"
|
|
"NP_001369715"
|
|
"NP_001369716"
|
|
"NP_001369717"
|
|
"NP_001369718"
|
|
"NP_001369719"
|
|
"NP_001369720"
|
|
"NP_001369721"
|
|
"NP_001369722"
|
|
"NP_001369723"
|
|
"NP_001369724"
|
|
"NP_001369725"
|
|
"NP_001369726"
|
|
"NP_001369727"
|
|
"NP_001369728"
|
|
"NP_001369729"
|
|
"NP_001369730"
|
|
"NP_001369731"
|
|
"NP_001369732"
|
|
"NP_001369733"
|
|
"NP_001369734"
|
|
"NP_001369735"
|
|
"NP_004439"
|
|
"XP_024306409"
|
|
"XP_024306410"
|
|
"XP_024306411"
|
|
wdt:P638
|
"1MFG"
|
|
"1MFL"
|
|
"1MW4"
|
|
"1N8Z"
|
|
"1QR1"
|
|
"1S78"
|
|
"2A91"
|
|
"2JWA"
|
|
"2KS1"
|
|
"2L4K"
|
|
"2N2A"
|
|
"3BE1"
|
|
"3H3B"
|
|
"3MZW"
|
|
"3N85"
|
|
"3PP0"
|
|
"3RCD"
|
|
"3WLW"
|
|
"3WSQ"
|
|
"4GFU"
|
|
"4HRL"
|
|
"4HRM"
|
|
"4HRN"
|
|
wdt:P646
|
"/m/08k67q"
|
|
wdt:P672
|
"D08.811.913.696.620.682.725.400.009.400"
|
|
"D12.776.476.568.400.009.400"
|
|
"D12.776.543.750.630.009.400"
|
|
"D12.776.543.750.750.400.074.400"
|
|
"D12.776.624.664.700.642"
|
|
"D23.050.301.500.600.700"
|
|
"D23.050.705.552.600.550"
|
|
"D23.101.140.642"
|
|
wdt:P680
|
identical protein binding
|
|
protein heterodimerization activity
|
|
ATP binding
|
|
protein C-terminus binding
|
|
protein kinase activity
|
|
transferase activity
|
|
nucleotide binding
|
|
protein dimerization activity
|
|
protein phosphatase binding
|
|
kinase activity
|
|
protein tyrosine kinase activity
|
|
transmembrane receptor protein tyrosine kinase activity
|
|
transmembrane signaling receptor activity
|
|
RNA polymerase I core binding
|
|
growth factor binding
|
|
ErbB-3 class receptor binding
|
|
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
|
protein binding
|
|
receptor tyrosine kinase
|
|
wdt:P681
|
integral component of membrane
|
|
perinuclear region of cytoplasm
|
|
membrane
|
|
apical plasma membrane
|
|
cytoplasmic vesicle
|
|
integral component of plasma membrane
|
|
basal plasma membrane
|
|
endosome membrane
|
|
basolateral plasma membrane
|
|
receptor complex
|
|
myelin sheath
|
|
cytosol
|
|
plasma membrane
|
|
nucleus
|
|
cytoplasm
|
|
wdt:P682
|
nervous system development
|
|
peptidyl-tyrosine phosphorylation
|
|
negative regulation of apoptotic process
|
|
regulation of transcription, DNA-templated
|
|
positive regulation of cell population proliferation
|
|
positive regulation of gene expression
|
|
MAPK cascade
|
|
positive regulation of cell growth
|
|
positive regulation of MAPK cascade
|
|
positive regulation of protein kinase B signaling
|
|
transcription, DNA-templated
|
|
cellular response to growth factor stimulus
|
|
positive regulation of protein phosphorylation
|
|
positive regulation of epithelial cell proliferation
|
|
cell surface receptor signaling pathway
|
|
positive regulation of ERK1 and ERK2 cascade
|
|
intracellular signal transduction
|
|
regulation of transcription by RNA polymerase II
|
|
oligodendrocyte differentiation
|
|
neuromuscular junction development
|
|
positive regulation of cell adhesion
|
|
regulation of cell motility
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
|
regulation of angiogenesis
|
|
positive regulation of translation
|
|
positive regulation of MAP kinase activity
|
|
enzyme linked receptor protein signaling pathway
|
|
positive regulation of transcription by RNA polymerase III
|
|
peripheral nervous system development
|
|
motor neuron axon guidance
|
|
myelination
|
|
phosphatidylinositol 3-kinase signaling
|
|
regulation of microtubule-based process
|
|
negative regulation of immature T cell proliferation in thymus
|
|
positive regulation of transcription by RNA polymerase I
|
|
regulation of ERK1 and ERK2 cascade
|
|
phosphatidylinositol phosphate biosynthetic process
|
|
neuron differentiation
|
|
negative regulation of signal transduction
|
|
positive regulation of GTPase activity
|
|
wound healing
|
|
cell population proliferation
|
|
cell differentiation
|
|
cellular response to epidermal growth factor stimulus
|
|
positive regulation of protein targeting to membrane
|
|
ERBB2 signaling pathway
|
|
negative regulation of ERBB signaling pathway
|
|
phosphorylation
|
|
protein autophosphorylation
|
|
development of the heart
|
|
protein phosphorylation
|
|
signal transduction
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20ERBB2%20216836%20s%20at.png>
|
|
wdt:P702
|
ERBB2
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000269571"
|
|
"ENSP00000385185"
|
|
"ENSP00000404047"
|
|
"ENSP00000446466"
|
|
"ENSP00000462024"
|
|
"ENSP00000462438"
|
|
"ENSP00000462808"
|
|
"ENSP00000463002"
|
|
"ENSP00000463427"
|
|
"ENSP00000463714"
|
|
"ENSP00000463719"
|
|
"ENSP00000464252"
|
|
"ENSP00000464420"
|
