SHMARQL

Plasminogen activator, tissue type

<http://www.wikidata.org/entity/Q416351>

protein involved in the breakdown of blood clots
rdfs:label
"Plasminogen activator, tissue type"@en
skos:altLabel
"PLAT"@en
"TPA"@en
"alteplase"@en
"plasminogen/activator kringle"@en
"reteplase"@en
"t-plasminogen activator"@en
"tissue-type plasminogen activator"@en
"uniprot:P00750"@en
schema:description
"protein involved in the breakdown of blood clots"@en
schema:dateModified "2026-07-23T06:51:45+00:00"^^xsd:dateTime
schema:version 2521519782
wikibase:identifiers 28
wikibase:sitelinks 21
wikibase:statements 90
p:P10283 wd:statement/Q416351-20F32D50-2215-4254-AF96-68C796A944B8
wd:statement/Q416351-520D771E-3CE5-4688-915E-59B69159DBA4
wd:statement/Q416351-E7608F8A-F37E-4F5D-A2B9-F392802B0C99
p:P129 wd:statement/Q416351-A52CAF11-186D-4146-8780-6E383AFFD836
p:P2888 wd:statement/Q416351-344AA287-DAC3-4C0A-AC61-378141782720
p:P31 wd:statement/Q416351-BD71413D-FB0C-4B42-85C7-3A1040FD7C18
p:P352 wd:statement/q416351-3183F0E0-9CF3-44E6-9062-F013521D60C9
p:P361 wd:statement/Q416351-09C271BC-1258-424C-B4D5-D24CB112EAA7
wd:statement/Q416351-16EA2721-76D9-4FF5-8F39-088E83F74A58
wd:statement/Q416351-434900CD-570C-484C-95B7-50E6B6CE1CCB
wd:statement/Q416351-53BD7CAD-1679-4A1D-96EF-F9B36CDD7BE4
wd:statement/Q416351-5FF89E9E-14C3-480C-A217-E46E24024F97
wd:statement/Q416351-6670BD89-04B5-4DEB-9A1E-4A09173F49B7
wd:statement/Q416351-70F44947-B1F7-43C2-B94C-2E4FA47D7FCD
wd:statement/Q416351-8281B822-07A4-40BC-B1B5-6E604E670795
wd:statement/Q416351-930F1FCA-2CF7-423F-907B-654EDFA989CB
wd:statement/Q416351-BF9A534F-0662-4053-8588-2F78C7321823
wd:statement/Q416351-C5213F76-25F6-4857-B8D3-35FF3CBC8D83
wd:statement/Q416351-EBE9AEAE-94BF-4C21-9306-4343F9CA6D00
p:P373 wd:statement/Q416351-C0202E73-2346-4604-AB6D-8BEED7E52143
p:P527 wd:statement/Q416351-0933E859-339A-41C9-8DA5-D9FF44ED0C8A
wd:statement/Q416351-2342CF7C-877E-4180-826A-0DC6EDC8D4C0
wd:statement/Q416351-430558B6-5B4E-4C5B-A4BC-C097BDE7828E
wd:statement/Q416351-7D6B7DDA-6668-4B86-90FD-CEE9EF1A6C06
wd:statement/Q416351-81AE418B-E732-456B-97CF-07FEFAE3BEAC
wd:statement/Q416351-A4720338-8963-44D7-BC3B-30A8B0ACF044
wd:statement/Q416351-BAB7C796-8B09-4F9F-A854-EF1C3EED868D
wd:statement/Q416351-F8C23ACC-5937-4CB8-AD10-C6AE5FD93223
p:P591 wd:statement/Q416351-A59BA690-BACE-46F5-ACAF-466A8EB0CAAE
p:P6366 wd:statement/Q416351-38AFA8E9-57CA-4DC6-8B72-4ABC767B5300
p:P637 wd:statement/Q416351-003284E8-0EF6-4BD0-89D3-916B18C5BEDD
wd:statement/Q416351-34BC1EE0-36B8-41C1-AD68-E8DD1838288F
wd:statement/Q416351-FCFF529F-F09D-42B6-9174-66C886765F53
p:P638 wd:statement/Q416351-2EC95343-C3AB-4BD2-96DE-964D7D680356
wd:statement/q416351-210A36EF-D821-4768-AE5F-0E8C268A82A6
wd:statement/q416351-23C5DE06-5056-4E61-8BCA-DF52649B3FE7
wd:statement/q416351-4621295C-6066-4048-AE09-9D7BA7A1C547
wd:statement/q416351-4EF6260D-BFFD-48B2-ADA1-7464CA4D6AF9
wd:statement/q416351-51642BAF-44DF-458E-9864-855F968E5E4E
wd:statement/q416351-532E2441-6BFD-4328-8194-5A8E894EF20B
wd:statement/q416351-93E74401-2F1B-4823-9381-E73EC2BB48AD
wd:statement/q416351-96140270-FB2D-4D1A-92FC-248024A27B67
wd:statement/q416351-B592563C-7768-4488-A7E1-4E2CDCE67A63
p:P646 wd:statement/Q416351-EB1FFE34-AC49-4288-9362-2C9FF59D82A0
p:P680 wd:statement/Q416351-0DC3FA72-49F0-4670-9D82-81450F793D0C
wd:statement/Q416351-132B668A-F693-435E-B14C-046CC4216A48
wd:statement/Q416351-928EFF63-54A7-4FB3-B7AC-2FD448B9B48C
wd:statement/Q416351-9E9A13A4-2C44-4E04-B04B-C88CB8D26301
wd:statement/Q416351-D1FB25BA-7F92-4C0F-8EE1-52534BB73976
wd:statement/Q416351-DF51514F-C33C-476D-A002-5D2641DE5859
wd:statement/Q416351-E1B7E6AB-814B-4272-8C49-FD3A2322A322
wd:statement/Q416351-E6B7E995-7EB3-4517-BD44-628B9CA2BFAC
p:P681 wd:statement/Q416351-086D706F-76B8-4A2C-91F1-57047006A7D3
wd:statement/Q416351-118604A9-79E6-4C4B-B34D-71D9BBB4F7CD
wd:statement/Q416351-279F335E-D819-4F47-8FA6-E33A6FDF9578
wd:statement/Q416351-33E47B36-ECBA-4216-94A3-898AD3691BE1
wd:statement/Q416351-3B5438E1-4FD5-4341-A1D4-567DED4DEAD0
wd:statement/Q416351-46CE86B3-C829-4EBE-ADBC-765FACDD0745
wd:statement/Q416351-48652265-96B8-472B-BE15-B9FC94B0A070
wd:statement/Q416351-4AD8BB77-DB99-4912-8A74-90836D56F534
wd:statement/Q416351-55380A90-0C1F-401D-A2F6-E8F99E04973D
wd:statement/Q416351-9E4BD560-3249-425C-A062-EA62C70FD67E
wd:statement/Q416351-A3C8E11E-EBCC-47CD-A97D-E6333566CAEF
wd:statement/Q416351-B725466D-5DB3-4482-9C0F-1EFB527191FF
wd:statement/Q416351-F97714B4-E515-4730-BBB7-71BD65E18212
p:P682 wd:statement/Q416351-02F7C2A3-F12D-4F30-AB3E-51877BAA6934
wd:statement/Q416351-29562C2D-AAE4-40F3-B3B3-97859009F5E0
wd:statement/Q416351-53600644-481F-4BD0-8722-94D4CDC08223
wd:statement/Q416351-8474990D-AAAD-4370-8DCA-723076816C62
wd:statement/Q416351-94466308-9EB3-47B4-AE12-29D49B12AC6D
wd:statement/Q416351-A3BA33B6-A2F6-407D-93B5-37ABF4D2D444
wd:statement/Q416351-B008FD2A-14F2-4186-928F-F6854A292A32
wd:statement/Q416351-B6C3EEE6-A506-4BEA-91B5-29AF35D387F6
wd:statement/Q416351-D294A77B-E1D7-4CD4-8BC6-E3BC55283393
wd:statement/Q416351-E5AA2A25-924E-497A-BE06-9AECBE004B32
wd:statement/Q416351-E887A155-3DEB-4D2C-BD65-BED5C8B94596
wd:statement/Q416351-F852F275-AE7C-4502-8EC9-F8B3128E155E
wd:statement/Q416351-FADAAB7A-6318-415F-B69D-8E9724094AFC
p:P692 wd:statement/Q416351-E6A658E0-0F20-46EE-906E-7AE7CF1C7BB1
p:P702 wd:statement/q416351-74CEFDEE-3E3F-4D86-A35D-7E78D68572E8
p:P703 wd:statement/Q416351-B07DB37D-1487-4549-8B97-943B29E368D9
p:P705 wd:statement/Q416351-6AE8BA6E-5219-4AE6-8BCB-FF4295CDB346
wd:statement/Q416351-83CF36D1-A0CB-43D2-8C69-32B9065C229A
wd:statement/Q416351-8A92E7B0-7517-4A1A-B9A4-964FA338A55A
wd:statement/Q416351-8EEB66C5-1716-426D-9CC5-98664A30D2FA
wd:statement/Q416351-D2CB9418-EE0F-4723-B2CD-1544F2381C5B
wd:statement/Q416351-E9710CB0-DCF3-430C-A595-F62E76BFB7DA
wd:statement/q416351-79851ECD-4BE4-4711-8EA8-ACAE5B0FE367
wd:statement/q416351-8FC75DCB-3DDA-4D89-AFF8-50CA8D5F12A7
wd:statement/q416351-C671F2AE-4690-419D-87EB-B204D3B7D98F
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P00750>
p:direct-normalized/P6366 <https://makg.org/entity/2776572282>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_000921>
<http://purl.uniprot.org/refseq/NP_001306118>
<http://purl.uniprot.org/refseq/NP_127509>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1A5H>
<https://rdf.wwpdb.org/pdb/1BDA>
<https://rdf.wwpdb.org/pdb/1PK2>
<https://rdf.wwpdb.org/pdb/1PML>
<https://rdf.wwpdb.org/pdb/1RTF>
<https://rdf.wwpdb.org/pdb/1TPG>
<https://rdf.wwpdb.org/pdb/1TPK>
<https://rdf.wwpdb.org/pdb/1TPM>
<https://rdf.wwpdb.org/pdb/1TPN>
<https://rdf.wwpdb.org/pdb/5BRR>
wdt:P10283 "C2776572282"
"C2909373784"
"C2911092318"
wdt:P129 aminocaproic acid
wdt:P2888 <http://purl.uniprot.org/uniprot/P00750>
wdt:P31 protein
wdt:P352 "P00750"
wdt:P361 tissue plasminogen activator
Kringle-like fold
Peptidase S1, PA clan
Kringle superfamily
EGF-like domain, protein family
Kringle domain, protein family
Fibronectin, type I, protein family
Serine proteases, trypsin domain, protein family
Kringle, conserved site, protein family
Serine proteases, trypsin family, serine active site, protein family
Serine proteases, trypsin family, histidine active site, protein family
EGF-like, conserved site, protein family
wdt:P373 "Tissue plasminogen activator"
wdt:P527 kringle, conserved site
EGF-like domain
Serine proteases, trypsin family, serine active site
serine proteases, trypsin family, histidine active site
kringle
fibronectin, type I
serine proteases, trypsin domain
EGF-like, conserved site
wdt:P591 "3.4.21.68"
wdt:P6366 "2776572282"
wdt:P637 "NP_000921"
"NP_001306118"
"NP_127509"
wdt:P638 "1A5H"
"1BDA"
"1PK2"
"1PML"
"1RTF"
"1TPG"
"1TPK"
"1TPM"
"1TPN"
"5BRR"
wdt:P646 "/m/02nrn3"
wdt:P680 serine-type peptidase activity
hydrolase activity
peptidase activity
signaling receptor binding
serine-type endopeptidase activity
phosphoprotein binding
protein binding
wdt:P681 extracellular space
apical part of cell
extracellular region
secretory granule
cell surface
extracellular matrix
glutamatergic synapse
Schaffer collateral - CA1 synapse
collagen-containing extracellular matrix
cytoplasm
extracellular exosome
wdt:P682 fibrinolysis
plasminogen activation
negative regulation of proteolysis
response to hypoxia
smooth muscle cell migration
platelet-derived growth factor receptor signaling pathway
blood coagulation
proteolysis
trans-synaptic signaling by BDNF, modulating synaptic transmission
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20PLAT%20201860%20s%20at%20fs.png>
wdt:P702 PLAT
wdt:P703 man
wdt:P705 "ENSP00000220809"
"ENSP00000270188"
"ENSP00000392045"
"ENSP00000407861"
"ENSP00000428797"
"ENSP00000428886"
"ENSP00000429401"
"ENSP00000429542"
"ENSP00000429801"
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data from SPARQL profile: Wikidata