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rdfs:label
|
"PTEN"@de
"PTEN"@es
"PTEN"@fi
"PTEN"@fr
"PTEN"@gl
"PTEN"@id
"PTEN"@ja
"PTEN"@pl
"PTEN"@pt
"PTEN"@ru
"PTEN"@uk
"PTEN"@zh
"PTEN"@bs
"PTEN"@ca
"PTEN"@ko
"PTEN"@hu
"Phosphatase and tensin homolog"@en
"Phosphatase and tensin homolog"@nl
"فتن"@ar
"同源性磷酸酶-张力蛋白"@zh-cn
"同源性磷酸酶-张力蛋白"@zh-hans
"同源性磷酸酶-张力蛋白"@zh-sg
"同源性磷酸酶-張力蛋白"@zh-hant
"同源性磷酸酶-張力蛋白"@zh-hk
"同源性磷酸酶-張力蛋白"@zh-tw
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|
skos:altLabel
|
"Gène PTEN"@fr
"MMAC1 phosphatase and tensin homolog deleted on chromosome 10"@en
"PTEN"@ar
"PTEN"@en
"PTENepsilon"@en
"Phosphatase PTEN"@de
"mitochondrial PTENalpha"@en
"mitochondrial phosphatase and tensin protein alpha"@en
"mutated in multiple advanced cancers 1"@en
"phosphatase and tensin-like protein"@en
"phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN"@en
"phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN"@en
"protein tyrosine phosphatase"@en
"بيه تي اي ان"@ar
"磷酸酶及张力蛋白同源体"@zh
"磷酸酶及张力蛋白同源基因"@zh
"磷酸酶及张力蛋白同源物"@zh
"磷酸酶和张力蛋白同源体"@zh
"磷酸酶和张力蛋白同源基因"@zh
"磷酸酶和张力蛋白同源物"@zh
|
|
schema:description
|
"Protein in Homo sapiens"@de
"gène"@fr
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in Phosphatase and tensin homolog"@nl
"protèin"@ace
"tumor suppressor gene"@en
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
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schema:dateModified
|
"2026-10-05T13:13:45+00:00"^^xsd:dateTime
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schema:version
|
2553457322
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wikibase:identifiers
|
17
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|
wikibase:sitelinks
|
19
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wikibase:statements
|
195
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p:P10283
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wd:statement/Q416356-24197AF8-2169-48CD-A968-699CA6B55BEA
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p:P18
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wd:statement/Q416356-DBACEABF-337E-46EE-9CFB-D8C00DAB58C1
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p:P2888
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wd:statement/Q416356-39EF17C6-BC56-4953-B34E-FB100B16B02C
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p:P31
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wd:statement/Q416356-9EA9E96D-3AF3-497F-BE4E-266F49E483AE
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p:P352
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wd:statement/q416356-9F494F2B-9CD1-47E4-85AA-A19B4BA8636D
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p:P361
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wd:statement/Q416356-26CCDFC4-45FD-4922-9C40-DC659A243537
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wd:statement/Q416356-37E41811-B51A-44D4-BD6D-8A8893F82AB8
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wd:statement/Q416356-3B4707B7-53F9-4362-8AC2-A4C8820E0485
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wd:statement/Q416356-4BE5C82A-7771-4442-B6F3-D45A288B73EF
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wd:statement/Q416356-5388D69E-8BFA-4456-8C1E-08D368D16553
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wd:statement/Q416356-8FE6A5F4-57AE-4E2E-982E-3B9EB9F00E84
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wd:statement/Q416356-A5BB71CC-5946-4CBE-8FF0-CA7E705A88A5
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p:P373
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wd:statement/Q416356-da049482-987d-485a-9f59-55c0d1cd0868
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p:P527
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wd:statement/Q416356-727E35A1-7F66-4CA7-B98A-30CE0D49D271
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wd:statement/Q416356-A7377C44-BFAF-42C8-908B-49171C87206E
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wd:statement/Q416356-CA277CD5-9A14-4492-B37B-8E13AB44C71A
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wd:statement/Q416356-CD0F2F52-4626-48A8-9060-C57F4457C834
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p:P591
|
wd:statement/Q416356-5E7FA460-97E6-4840-8ADE-1A27025F30B3
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|
wd:statement/Q416356-7DD015F7-B712-43B7-95A3-5D5B57E2BEB9
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wd:statement/Q416356-C6ABED3D-B4B4-452B-938D-2F76588F0522
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p:P6366
|
wd:statement/Q416356-D4B3D818-72DD-4A14-8CAD-1E6ABCBFF5D1
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p:P637
|
wd:statement/Q416356-431BFAAC-C298-4AD3-B67A-759442097165
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wd:statement/Q416356-601C89BA-26C0-4C07-90B8-CB1D02334C5C
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wd:statement/Q416356-ED25B87C-EC50-4954-9FAD-65525D987106
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p:P638
|
wd:statement/Q416356-05FFA27C-4F2C-45EB-93C4-5F4E69100719
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wd:statement/Q416356-15D1B747-08BB-4FE1-A847-D5FCDECB6FE0
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wd:statement/Q416356-52A0BF4D-2EC8-431C-A84A-E6EAB0CEBB0A
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wd:statement/Q416356-562A36FD-045D-4322-998A-F4609DEECF94
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wd:statement/Q416356-617109EB-F00D-4FF6-822E-6981E8BF9C8F
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wd:statement/Q416356-7A6E6FB7-4E77-4E9A-A789-D9350B54A291
|
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p:P646
|
wd:statement/Q416356-7E9BD72A-9FE9-4DA5-958A-3D6C8BE13318
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p:P680
|
wd:statement/Q416356-0259D539-CA7E-4295-9FA2-D3B93D54DFE8
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wd:statement/Q416356-08693C0F-7A1D-48C3-813F-E62B81DFBF5C
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wd:statement/Q416356-1B874727-55AC-49C5-B8DD-FC8015B37256
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wd:statement/Q416356-1C963DD6-D892-49FF-9405-F0E9D2B953D5
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wd:statement/Q416356-1DC38EA3-DAB4-4317-BFA9-7DA780DFA057
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wd:statement/Q416356-235E2CA1-A3A9-4EA4-A264-6CAB6C694A70
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wd:statement/Q416356-33949E39-27F9-420F-B0DB-5D3D6016963E
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wd:statement/Q416356-673A383B-DA94-4D9A-8CB1-F943C4919319
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wd:statement/Q416356-6A2666D6-6263-48C3-A844-323AF5987355
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wd:statement/Q416356-716E1113-991B-4C93-B9C6-BD82F73D33F3
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wd:statement/Q416356-72809A9C-1D35-4D4B-BAF6-3DB550983DB2
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wd:statement/Q416356-768644A6-5651-4FD6-9084-1D462EE970BD
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wd:statement/Q416356-8F6C8019-90E6-44E6-8A04-5676BDEDAD73
|
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wd:statement/Q416356-8F72ED8E-D497-41CA-94DB-B403321B65C2
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wd:statement/Q416356-A5C95042-D263-4901-A132-7E16D10C911D
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wd:statement/Q416356-ABC685FA-6587-4388-9447-EEA36240A098
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wd:statement/Q416356-DB2DB8FF-66B3-4299-A11E-8DCFFDA1A52A
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wd:statement/Q416356-EFA83C3B-80BB-407F-82BF-C80CEFC0EF0E
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wd:statement/Q416356-F6710A1B-F5EB-44CA-8E46-2E7F95F4EB30
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wd:statement/Q416356-FA3F039C-EC34-4F30-9FAE-E66F28B07301
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p:P681
|
wd:statement/Q416356-06E88F2D-C6A3-40D0-AB48-706C501355E2
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wd:statement/Q416356-0D411CB4-7D7B-44B3-9748-CF639A20678D
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wd:statement/Q416356-369D6C91-10EB-4B89-B255-82B343BE06C0
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wd:statement/Q416356-6B57FC06-7C61-498B-8E64-17C5D30A3BBE
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wd:statement/Q416356-6ED8C4C4-3FBB-4E85-90BF-425033C47E9F
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wd:statement/Q416356-6FA85223-2A61-409F-8DA7-26465C9172B3
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wd:statement/Q416356-7D39B172-32A8-420B-A077-D0179A9EC57A
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wd:statement/Q416356-8821A0E3-7A29-487E-93F1-A7A73B1BC8CD
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wd:statement/Q416356-8A792ED3-DC55-484D-9257-215AAFB1E9BB
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wd:statement/Q416356-8EE351B8-0E0F-4B63-85EF-5E92D7BA0D96
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wd:statement/Q416356-918EDC5A-9E31-411A-B533-CD3D4183BA72
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wd:statement/Q416356-9204B40A-4053-44F3-AF1E-2A30221219F3
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wd:statement/Q416356-954C920D-E12C-4F93-B97A-80C2A4973532
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wd:statement/Q416356-B28B5274-5453-4848-8B87-E9C4EAA93945
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wd:statement/Q416356-C80799BD-AA2A-4BBC-958D-C6DA39DAF30F
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wd:statement/Q416356-DFC3477E-2459-4908-8967-EA3642FC4240
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wd:statement/Q416356-F3B863C0-E6AE-49D7-B510-800E947A1F3D
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p:P682
|
wd:statement/Q416356-004677D8-6163-40B2-AB6C-1B71C6BD7FBE
|
|
wd:statement/Q416356-032B38CA-32FF-4E3D-B302-DCDC52F109B1
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wd:statement/Q416356-05C5FC07-57DF-4997-8B12-D8025370D848
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wd:statement/Q416356-05E06491-43AC-4B02-B273-8CE0CDA24572
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wd:statement/Q416356-0765C1F1-EA23-456A-8DAF-106E45B8EC64
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wd:statement/Q416356-0DF50CD7-D426-468F-A250-A8E865D94D01
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wd:statement/Q416356-0E176752-40EB-4EF8-BC7D-31A6EB05206F
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wd:statement/Q416356-10AED191-0B83-46D9-B9E8-320D07C06E50
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wd:statement/Q416356-1429215F-E8E3-40EB-BC34-3CE41932FBF9
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wd:statement/Q416356-16B66DE5-F7CF-4344-83F2-E898F125585F
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wd:statement/Q416356-16CA613F-6E79-4897-98EA-36FF9A5F61AA
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wd:statement/Q416356-188C29E9-B991-4030-9D8E-C6499CFCA2EE
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wd:statement/Q416356-18D88069-442B-46EC-A2FA-18ECF0E3F06C
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wd:statement/Q416356-1A0BFBF0-3D6E-4F41-9673-1220059E9639
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wd:statement/Q416356-1D8BA47E-1860-46C7-B44E-17D941BCB959
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wd:statement/Q416356-1DF5E7C2-3E4B-4D3F-9CED-AFDD41975C0C
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wd:statement/Q416356-1E3B8C89-4024-44DE-A2B8-C0C7485A7170
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wd:statement/Q416356-1FCD1F40-A30C-496B-A52E-CC488F7096F6
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wd:statement/Q416356-2052F020-D890-4EC2-935C-0DE876884738
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wd:statement/Q416356-2112507B-3256-48A1-B8D4-02FF12A21ED7
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wd:statement/Q416356-2396036D-E525-41C9-B3B7-821412649EBF
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wd:statement/Q416356-24A5A594-6602-4D63-826A-4C64610995ED
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wd:statement/Q416356-2C365566-1E1B-4188-8012-ED8605E89D22
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wd:statement/Q416356-3B66CB61-FB58-4477-B4B6-473F6DFF60AD
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wd:statement/Q416356-3BEEF6E7-2F4D-43E5-9867-52285749D123
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wd:statement/Q416356-40F511F2-B275-4486-BE92-E57905BE8CA2
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wd:statement/Q416356-4462F3A4-DE18-489C-A05C-32EA02441429
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wd:statement/Q416356-44A14223-D957-4C39-BD99-AA455D5609DD
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wd:statement/Q416356-4D1FA08E-EEE2-472D-8EC8-5D40764AC77C
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wd:statement/Q416356-513BB31D-CA17-435B-B62A-AFE80B8626A4
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wd:statement/Q416356-5E94C064-DECA-48EA-8B3E-985A66A3B4FD
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wd:statement/Q416356-5FDF3CBC-E82B-4B2B-8680-BDF8B9991AFB
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wd:statement/Q416356-60514F2B-7738-4113-8A06-69AB73C8D398
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wd:statement/Q416356-E40EA016-10BB-40CE-ABD4-9E0B285AA0B6
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wd:statement/Q416356-E567617F-4D8A-4BF7-919D-81A5B01A0D27
|
|
wd:statement/Q416356-E609BCC6-F7DC-4A6D-B923-3DCDE5EC773A
|
|
wd:statement/Q416356-E77DE28D-D5EB-4D0C-84C9-03B250A84EE1
|
|
wd:statement/Q416356-E8A473F7-276A-4E17-A6ED-D7811781F76D
|
|
wd:statement/Q416356-E9C391CC-7E6B-41F4-8ECA-4BCCD05CCEC3
|
|
wd:statement/Q416356-EB3FA2B3-5172-4197-88DC-55FA99F79CC3
|
|
wd:statement/Q416356-EC58E707-6DD4-47EC-9999-E541B50FC754
|
|
wd:statement/Q416356-EDE2E70A-4245-4575-A716-5407AAA0F1E2
|
|
wd:statement/Q416356-EFFD640D-8995-4DD6-A96B-F672A1922844
|
|
wd:statement/Q416356-F217B276-67C8-478F-9403-DCCF4FAA14F7
|
|
wd:statement/Q416356-F22C2CDD-3515-44FC-B63A-88E76637D76F
|
|
wd:statement/Q416356-F442F907-8C89-42C4-8EAE-047AC4B27AEE
|
|
wd:statement/Q416356-F4FBF8F4-53C8-43BE-B27D-6478E3BBDDCB
|
|
wd:statement/Q416356-F52A5397-76C4-48F7-AE60-90CDC4E87961
|
|
wd:statement/Q416356-F64CA01A-E7C3-476A-8158-1925C678C3B5
|
|
wd:statement/Q416356-FEDFD8BF-3F34-47E4-837E-C9823B0FF56C
|
|
p:P702
|
wd:statement/q416356-8E8E9942-1E8A-44A9-99C8-56BC86D4D622
|
|
p:P703
|
wd:statement/Q416356-9DA43B7E-8C3D-4C63-8197-550052A0CA7C
|
|
p:P705
|
wd:statement/Q416356-0214FBBB-2D3D-4D26-A785-8BC6E59D31CB
|
|
wd:statement/Q416356-1E0CC7AB-5B37-489A-B00B-90BDBF73FCFB
|
|
wd:statement/Q416356-ABFE61B4-0A84-44C0-85E5-39BCDAADA03F
|
|
wd:statement/q416356-9DDCE1C2-8388-4495-A038-2DC0E2FC2119
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P60484>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/2777609662>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_000305>
|
|
<http://purl.uniprot.org/refseq/NP_001291646>
|
|
<http://purl.uniprot.org/refseq/NP_001291647>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1D5R>
|
|
<https://rdf.wwpdb.org/pdb/2KYL>
|
|
<https://rdf.wwpdb.org/pdb/4O1V>
|
|
<https://rdf.wwpdb.org/pdb/5BUG>
|
|
<https://rdf.wwpdb.org/pdb/5BZX>
|
|
<https://rdf.wwpdb.org/pdb/5BZZ>
|
|
wdt:P10283
|
"C2777609662"
|
|
wdt:P18
|
<http://commons.wikimedia.org/wiki/Special:FilePath/Pten.jpg>
|
|
wdt:P2888
|
<http://purl.uniprot.org/uniprot/P60484>
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P60484"
|
|
wdt:P361
|
Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN
|
|
Protein-tyrosine phosphatase-like
|
|
Dual specificity phosphatase
|
|
Tensin-type phosphatase domain, protein family
|
|
Protein-tyrosine phosphatase, catalytic domain, protein family
|
|
Tensin phosphatase, C2 domain, protein family
|
|
Protein-tyrosine phosphatase, active site, protein family
|
|
wdt:P373
|
"PTEN phosphohydrolase"
|
|
wdt:P527
|
Tensin-type phosphatase domain
|
|
Protein-tyrosine phosphatase, catalytic
|
|
Protein-tyrosine phosphatase, active site
|
|
Tensin phosphatase, C2 domain
|
|
wdt:P591
|
"3.1.3.16"
|
|
"3.1.3.48"
|
|
"3.1.3.67"
|
|
wdt:P6366
|
"2777609662"
|
|
wdt:P637
|
"NP_000305"
|
|
"NP_001291646"
|
|
"NP_001291647"
|
|
wdt:P638
|
"1D5R"
|
|
"2KYL"
|
|
"4O1V"
|
|
"5BUG"
|
|
"5BZX"
|
|
"5BZZ"
|
|
wdt:P646
|
"/m/096cc3"
|
|
wdt:P680
|
hydrolase activity
|
|
lipid binding
|
|
enzyme binding
|
|
identical protein binding
|
|
protein kinase binding
|
|
PDZ domain binding
|
|
ionotropic glutamate receptor binding
|
|
phosphatidylinositol-3-phosphatase activity
|
|
phosphoprotein phosphatase activity
|
|
protein tyrosine phosphatase activity
|
|
protein tyrosine/serine/threonine phosphatase activity
|
|
anaphase-promoting complex binding
|
|
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
|
|
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
|
|
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
|
|
platelet-derived growth factor receptor binding
|
|
protein binding
|
|
ubiquitin-specific protease binding
|
|
protein serine/threonine phosphatase activity
|
|
protein tyrosine kinase binding
|
|
wdt:P681
|
myelin sheath adaxonal region
|
|
cell projection
|
|
extracellular region
|
|
neuron projection
|
|
nucleoplasm
|
|
PML body
|
|
apical plasma membrane
|
|
postsynaptic membrane
|
|
cytoplasmic side of plasma membrane
|
|
Schmidt-Lanterman incisure
|
|
cytosol
|
|
postsynaptic cytosol
|
|
plasma membrane
|
|
mitochondrion
|
|
nucleus
|
|
cytoplasm
|
|
dendritic spine
|
|
wdt:P682
|
dephosphorylation
|
|
prepulse inhibition
|
|
maternal behavior
|
|
nervous system development
|
|
central nervous system development
|
|
positive regulation of excitatory postsynaptic potential
|
|
apoptotic process
|
|
negative regulation of cell population proliferation
|
|
negative regulation of apoptotic process
|
|
positive regulation of cell population proliferation
|
|
positive regulation of gene expression
|
|
response to estradiol
|
|
protein stabilization
|
|
locomotory behavior
|
|
dentate gyrus development
|
|
postsynaptic density assembly
|
|
canonical Wnt signaling pathway
|
|
positive regulation of apoptotic process
|
|
cellular response to hypoxia
|
|
positive regulation of cardiac muscle cell apoptotic process
|
|
regulation of cell cycle
|
|
learning or memory
|
|
response to ethanol
|
|
response to activity
|
|
male mating behavior
|
|
response to organic cyclic compound
|
|
positive regulation of ERK1 and ERK2 cascade
|
|
positive regulation of neuron differentiation
|
|
response to zinc ion
|
|
negative regulation of cell migration
|
|
endothelial cell migration
|
|
transcription initiation from RNA polymerase II promoter
|
|
response to nutrient
|
|
negative regulation of organ growth
|
|
brain morphogenesis
|
|
negative regulation of protein phosphorylation
|
|
response to organic substance
|
|
platelet-derived growth factor receptor signaling pathway
|
|
cellular response to insulin stimulus
|
|
cellular response to leptin stimulus
|
|
protein dephosphorylation
|
|
regulation of protein stability
|
|
prostate gland growth
|
|
negative regulation of ERK1 and ERK2 cascade
|
|
response to glucose
|
|
negative regulation of phagocytosis
|
|
protein deubiquitination
|
|
neuron projection development
|
|
response to arsenic-containing substance
|
|
positive regulation of DNA-binding transcription factor activity
|
|
positive regulation of ubiquitin-dependent protein catabolic process
|
|
negative regulation of neuron projection development
|
|
multicellular organismal response to stress
|
|
negative regulation of cyclin-dependent protein serine/threonine kinase activity
|
|
phosphatidylinositol biosynthetic process
|
|
positive regulation of apoptotic signaling pathway
|
|
negative regulation of epithelial cell proliferation
|
|
cardiac muscle tissue development
|
|
adult behavior
|
|
negative regulation of cell size
|
|
negative regulation of axonogenesis
|
|
regulation of B cell apoptotic process
|
|
neuron-neuron synaptic transmission
|
|
regulation of neuron projection development
|
|
negative regulation of phosphatidylinositol 3-kinase signaling
|
|
central nervous system neuron axonogenesis
|
|
negative regulation of myelination
|
|
central nervous system myelin maintenance
|
|
regulation of cellular component size
|
|
regulation of myeloid cell apoptotic process
|
|
peptidyl-tyrosine dephosphorylation
|
|
protein kinase B signaling
|
|
inositol phosphate metabolic process
|
|
locomotor rhythm
|
|
inositol phosphate dephosphorylation
|
|
phosphatidylinositol dephosphorylation
|
|
forebrain morphogenesis
|
|
negative regulation of focal adhesion assembly
|
|
negative regulation of protein kinase B signaling
|
|
rhythmic synaptic transmission
|
|
synapse maturation
|
|
dendritic spine morphogenesis
|
|
negative regulation of dendritic spine morphogenesis
|
|
negative regulation of ribosome biogenesis
|
|
negative regulation of excitatory postsynaptic potential
|
|
presynaptic membrane assembly
|
|
negative regulation of G1/S transition of mitotic cell cycle
|
|
negative regulation of synaptic vesicle clustering
|
|
regulation of synaptic transmission, GABAergic
|
|
response to inorganic substance
|
|
cellular response to nerve growth factor stimulus
|
|
cellular response to ethanol
|
|
response to ATP
|
|
negative regulation of potassium ion transmembrane transporter activity
|
|
negative regulation of cardiac muscle cell proliferation
|
|
negative regulation of epithelial to mesenchymal transition
|
|
negative regulation of signaling receptor activity
|
|
long-term depression
|
|
long-term potentiation
|
|
synapse assembly
|
|
cell migration
|
|
cell population proliferation
|
|
regulation of axon regeneration
|
|
regulation of cellular localization
|
|
negative regulation of axon regeneration
|
|
cellular response to decreased oxygen levels
|
|
regulation of cyclin-dependent protein serine/threonine kinase activity
|
|
cellular response to electrical stimulus
|
|
negative regulation of wound healing, spreading of epidermal cells
|
|
positive regulation of TRAIL-activated apoptotic signaling pathway
|
|
cellular response to insulin-like growth factor stimulus
|
|
positive regulation of ubiquitin protein ligase activity
|
|
negative regulation of keratinocyte migration
|
|
negative regulation of vascular associated smooth muscle cell proliferation
|
|
lipid metabolism
|
|
ageing
|
|
development of the heart
|
|
memory
|
|
angiogenesis
|
|
social behavior
|
|
wdt:P702
|
PTEN
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000361021"
|
|
"ENSP00000483066"
|
|
"ENSP00000494918"
|
|
"ENSP00000495622"
|
