SHMARQL

Hypoxanthine phosphoribosyltransferase 1

<http://www.wikidata.org/entity/Q418137>

mammalian protein found in Homo sapiens
Hypoxanthine phosphoribosyltransferase 1
rdfs:label
"Hypoxanthine phosphoribosyltransferase 1"@en
skos:altLabel
"HGPRT"@en
"HGPRTase"@en
"HPRT"@en
"HPRT1"@en
"hypoxanthine-guanine phosphoribosyltransferase"@en
"hypoxanthine-guanine phosphoribosyltransferase 1"@en
"testicular tissue protein Li 89"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-07-23T06:51:58+00:00"^^xsd:dateTime
schema:version 2521519817
wikibase:identifiers 22
wikibase:sitelinks 0
wikibase:statements 81
p:P18 wd:statement/Q418137-25D76576-D0F1-40D9-AF03-3089275D0C65
p:P2888 wd:statement/Q418137-C68C2EE3-2EC8-4867-B2A3-EF839D684499
p:P31 wd:statement/Q418137-1E9956C6-C4AE-49D2-8C83-3CC22A451224
p:P352 wd:statement/q418137-6FFA421B-8E96-4203-B291-4570BAD00045
p:P361 wd:statement/Q418137-C94CA32E-0EBC-4058-B20E-457617FDEB46
wd:statement/Q418137-D6AEDA67-536C-48E2-B130-F2C1DC6BAEEF
wd:statement/Q418137-F0FD12F2-1CB4-4F7B-A4D1-FB1F57CABC36
p:P527 wd:statement/Q418137-0745796F-6CDE-40AA-9B36-1515475FD227
p:P591 wd:statement/Q418137-CEEC2773-112F-4D1F-B570-80D86CA72282
p:P637 wd:statement/Q418137-2F53A43F-19ED-4817-955B-91F59E0F1C24
p:P638 wd:statement/Q418137-3965A1CF-6466-4D58-BCAC-B023A58D4F29
wd:statement/Q418137-484E90E2-6E73-46F1-9CEF-7E02B531F167
wd:statement/Q418137-6F85E386-AD17-41DB-80AD-E138B73417EA
wd:statement/Q418137-A3A1B41C-EA69-419E-B1BC-71E012087DD0
wd:statement/Q418137-BE4B7289-19B6-4D76-8F32-8C2201E1E02B
wd:statement/Q418137-CA98E6BD-ADC0-4A4D-ACF0-44B0B654A7A2
wd:statement/Q418137-D156C91E-75D4-48CD-A257-1DA755B818A1
wd:statement/Q418137-D605AE2A-0094-4B41-8130-ECB21CF116FC
wd:statement/Q418137-DBE0CB5C-2A06-4FFB-AF99-900D4D1AFE55
wd:statement/Q418137-DFC84FAE-1F19-409E-9962-0C2A0A438122
wd:statement/Q418137-F33B0C1E-E2D0-43E7-B813-C47657DC51B9
wd:statement/q418137-05CE0A38-A4B9-490E-99E4-A26A919A993D
wd:statement/q418137-2020A332-65CA-4D77-80E6-C41AA6892D15
wd:statement/q418137-75E205BC-78B7-49F5-B358-36AB29EF2ED9
wd:statement/q418137-B3B5BA59-7D76-425F-B521-02FEE8F07891
wd:statement/q418137-BB7458B2-5077-4E88-8C2A-5CF00B79C3E9
wd:statement/q418137-C078FA17-F97B-4900-AC6C-6DBBFBBFC1CC
wd:statement/q418137-DB62B5D4-F9A2-4544-B15B-86D2E5DCFBF9
p:P646 wd:statement/Q418137-7089E6BF-AEC5-4E1E-9C21-8A6FB8BBC1AE
p:P680 wd:statement/Q418137-1A2CDC8B-EA83-4FA5-8306-219D463F4D3A
wd:statement/Q418137-25D7B089-BEC0-4814-B641-EAC3E7EA0B1C
wd:statement/Q418137-378C483D-A630-4389-9B75-662BAD9012DC
wd:statement/Q418137-3FE766B4-5A79-49BC-88CF-C99A07650C5A
wd:statement/Q418137-48F397C2-370D-40E6-A886-68E6A50822EE
wd:statement/Q418137-51D236E1-11FD-4959-9A67-08A4E5C23EE1
wd:statement/Q418137-6BCEED5C-7971-43F5-B17B-ADAF7FE7D302
wd:statement/Q418137-7520CC33-DC98-4988-9147-9FA653B9D410
wd:statement/Q418137-9F0CFC8D-97B0-4E60-8EB2-A7E0BD542814
wd:statement/Q418137-B2EED850-B1B4-4FC2-BD12-13DAB451704B
wd:statement/Q418137-B95328BD-790E-4194-AE09-C2DE0B62D5DD
wd:statement/Q418137-D93CB093-DF8B-4E2D-AA51-8ED9D4DB792D
wd:statement/Q418137-E0795F46-27BF-4AE0-A732-BA03E9CED7B4
p:P681 wd:statement/Q418137-091DAFD6-7D99-46D2-A27C-FD98E9E42FB4
wd:statement/Q418137-26468037-3F9F-4086-884A-EF5300053CD6
wd:statement/Q418137-41B50250-8E1A-4059-A5D9-48A87FBCBC12
wd:statement/Q418137-7F854938-71C7-4C01-99EE-2C6D6347259C
p:P682 wd:statement/Q418137-12C34126-FD45-4B4E-8E05-17DA35D2EA4D
wd:statement/Q418137-145599EE-1640-4866-9B6D-314B918E1177
wd:statement/Q418137-2F5CB4D5-A8B0-47B7-9F13-30C689CC7DDE
wd:statement/Q418137-3157621F-F8D7-439C-9973-D15FCAA62069
wd:statement/Q418137-33A8BCC6-10EB-44C3-A231-E4C98AC8CD90
wd:statement/Q418137-38CBE557-F14E-4F47-9A19-868A40B6B96B
wd:statement/Q418137-4C462205-15D4-4353-91A0-DED0C3F27A96
wd:statement/Q418137-53AE4BAA-8A3E-4948-BBB2-97B59D4D8E99
wd:statement/Q418137-5515EAD7-EFD2-4541-897E-9E6256A902D1
wd:statement/Q418137-6162EA83-7328-415C-86EA-E7BE68EBF11A
wd:statement/Q418137-684C9C45-B5B1-4F2B-A3F2-0EB15AEAD3CD
wd:statement/Q418137-7ED19A46-7E0B-4E80-B3EA-CE0FEA2169ED
wd:statement/Q418137-7F1DECAA-4CCB-418F-9761-781A78C00E60
wd:statement/Q418137-8949D170-9F52-4505-9874-8C033C9DF126
wd:statement/Q418137-8F170923-B27E-4D29-9C8C-C68C49041385
wd:statement/Q418137-9065A09B-72AE-4E0E-95FB-70A9E038B230
wd:statement/Q418137-92BF0CE6-0032-4DD4-97F2-C1ACFB512311
wd:statement/Q418137-99C77DBB-C01C-4B7B-A672-5AE36EEE4C95
wd:statement/Q418137-9AE78462-15C3-43AA-99D0-2B1123DCB4FE
wd:statement/Q418137-9BB1D5C7-9FD7-49A2-A509-38671DBDB301
wd:statement/Q418137-AF18F060-EFA0-4FF1-82CE-50E591F3D3AD
wd:statement/Q418137-AF69586B-A618-4695-936B-C6F04E974B58
wd:statement/Q418137-AFECAD3F-4BDE-403E-BB0E-078DBC5C6D18
wd:statement/Q418137-C98F34CA-5E9A-4FE2-BAFF-01EEE308DDDA
wd:statement/Q418137-CFBD2847-63F4-4CE4-833D-45E3ADC97001
wd:statement/Q418137-D651B2B9-31C1-469F-AC44-97F5AAA7EE4A
wd:statement/Q418137-DD78C9E0-5262-4CFC-BDAD-571D9399C058
wd:statement/Q418137-E27F58D6-AC23-49AE-B534-649CC0419E46
wd:statement/Q418137-EDC11B94-EC50-4B9B-9AED-4B95A93C31F0
wd:statement/Q418137-F5CC9FAB-F2BA-4118-AF9C-56F909F9ED3B
wd:statement/Q418137-FA22886F-220E-4057-B63E-3F4698AA9576
p:P692 wd:statement/Q418137-3FE33FA1-FCCF-438B-95EE-62D4116C71C8
p:P702 wd:statement/q418137-65767B2D-2DC7-4EF0-9CE7-DF2274F901CD
p:P703 wd:statement/Q418137-5940ACBD-1F2E-4E84-9C44-D5F128C61AAD
p:P705 wd:statement/q418137-D44B70A8-7281-4EEB-BFB3-EABB5B81D51C
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P00492>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_000185>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1BZY>
<https://rdf.wwpdb.org/pdb/1D6N>
<https://rdf.wwpdb.org/pdb/1HMP>
<https://rdf.wwpdb.org/pdb/1Z7G>
<https://rdf.wwpdb.org/pdb/2VFA>
<https://rdf.wwpdb.org/pdb/3GEP>
<https://rdf.wwpdb.org/pdb/3GGC>
<https://rdf.wwpdb.org/pdb/3GGJ>
<https://rdf.wwpdb.org/pdb/4IJQ>
<https://rdf.wwpdb.org/pdb/4KN6>
<https://rdf.wwpdb.org/pdb/4RAB>
<https://rdf.wwpdb.org/pdb/4RAC>
<https://rdf.wwpdb.org/pdb/4RAD>
<https://rdf.wwpdb.org/pdb/4RAN>
<https://rdf.wwpdb.org/pdb/4RAO>
<https://rdf.wwpdb.org/pdb/4RAQ>
<https://rdf.wwpdb.org/pdb/5BRN>
<https://rdf.wwpdb.org/pdb/5BSK>
wdt:P18 <http://commons.wikimedia.org/wiki/Special:FilePath/Hypoxanthine-guanine%20phosphoribosyltransferase%201BZY.png>
wdt:P2888 <http://purl.uniprot.org/uniprot/P00492>
wdt:P31 protein
wdt:P352 "P00492"
wdt:P361 Phosphoribosyltransferase-like
Hypoxanthine phosphoribosyl transferase
Phosphoribosyltransferase domain, protein family
wdt:P527 Phosphoribosyltransferase domain
wdt:P591 "2.4.2.8"
wdt:P637 "NP_000185"
wdt:P638 "1BZY"
"1D6N"
"1HMP"
"1Z7G"
"2VFA"
"3GEP"
"3GGC"
"3GGJ"
"4IJQ"
"4KN6"
"4RAB"
"4RAC"
"4RAD"
"4RAN"
"4RAO"
"4RAQ"
"5BRN"
"5BSK"
wdt:P646 "/m/04c4cz"
wdt:P680 metal ion binding
identical protein binding
protein homodimerization activity
transferase activity
glycosyltransferase activity
nucleotide binding
magnesium ion binding
hypoxanthine phosphoribosyltransferase activity
guanine phosphoribosyltransferase activity
protein binding
wdt:P681 cytosol
cytoplasm
extracellular exosome
wdt:P682 locomotory behavior
protein homotetramerization
response to amphetamine
central nervous system neuron development
nucleoside metabolic process
dopamine metabolic process
purine nucleotide biosynthetic process
purine ribonucleoside salvage
adenine salvage
guanine salvage
striatum development
cerebral cortex neuron differentiation
GMP salvage
IMP salvage
purine-containing compound salvage
hypoxanthine salvage
positive regulation of dopamine metabolic process
GMP catabolic process
IMP metabolic process
hypoxanthine metabolic process
lymphocyte proliferation
dendrite morphogenesis
adenine metabolic process
T cell mediated cytotoxicity
cytolysis
grooming behavior
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20HPRT1%20202854%20at%20fs.png>
wdt:P702 HPRT1
wdt:P703 man
wdt:P705 "ENSP00000298556"
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data from SPARQL profile: Wikidata