anaphase-promoting complex

ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which
rdfs:label
"anaphase-promoting complex"@en
skos:altLabel
"APC"@en
"GO:0005680"@en
"anaphase promoting complex"@en
"cyclosome"@en
schema:description
"ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which"@en
schema:dateModified "2026-09-27T21:26:57+00:00"^^xsd:dateTime
schema:version 2550174880
wikibase:identifiers 7
wikibase:sitelinks 13
wikibase:statements 12
p:P10283 wd:statement/Q418432-60A79A52-7F22-45B7-9473-3FF8E969756B
p:P10376 wd:statement/Q418432-530797AA-20D1-4691-A9FA-DF10FAA4CAEE
p:P227 wd:statement/Q418432-3EFDB5B7-2EB1-40E0-A92F-2124DAD902E1
p:P279 wd:statement/Q418432-54A135EE-BE21-42D5-B501-B2C353C6F43A
wd:statement/Q418432-8AC5853D-7B4E-4329-A705-98CF85852431
p:P2888 wd:statement/Q418432-CB15CBFC-DE5F-4F64-91E7-6DD0F80CF1EF
p:P2892 wd:statement/Q418432-F9B33287-E9D1-4041-82E5-D4CEA7AF059E
p:P31 wd:statement/Q418432-26887B74-8762-4B07-AAB4-AC89E2ED8D3E
p:P373 wd:statement/q418432-CC5F0DF4-BE0C-4ED6-BE75-41DD6F281229
p:P6366 wd:statement/Q418432-D190CA13-285F-40C2-B011-4DA0EBC7E050
p:P646 wd:statement/Q418432-28CDB82A-D662-4157-9718-4BC6F26B7367
p:P686 wd:statement/Q418432-079C1B45-11C5-4A6D-B3C4-3EEE2656B241
p:direct-normalized/P227 <https://d-nb.info/gnd/7534837-8>
p:direct-normalized/P6366 <https://makg.org/entity/107888121>
wdt:P10283 "C107888121"
wdt:P10376 "agricultural-and-biological-sciences/anaphase-promoting-complex"
wdt:P227 "7534837-8"
wdt:P279 nuclear ubiquitin ligase complex
cullin-RING ubiquitin ligase complex
wdt:P2888 <http://purl.obolibrary.org/obo/GO_0005680>
wdt:P2892 "C1176286"
wdt:P31 cellular component
wdt:P373 "Anaphase promoting complex (APC)"
wdt:P6366 "107888121"
wdt:P646 "/m/02gtxq"
wdt:P686 "GO:0005680"
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