SHMARQL

TNF superfamily member 11

<http://www.wikidata.org/entity/Q418934>

mammalian protein found in Homo sapiens
TNF superfamily member 11
rdfs:label
"TNF superfamily member 11"@en
skos:altLabel
"ODF"@en
"OPGL"@en
"RANK ligand"@en
"RANKL"@en
"Receptor activator of nuclear factor kappa-B ligand"@en
"TNF-related activation-induced cytokine"@en
"TNFSF11"@en
"TRANCE"@en
"osteoclast differentiation factor"@en
"osteoprotegerin ligand"@en
"receptor activator of nuclear factor kappa B ligand"@en
"tumor necrosis factor (ligand) superfamily, member 11"@en
"tumor necrosis factor ligand 6B"@en
"tumor necrosis factor ligand superfamily member 11"@en
"tumor necrosis factor superfamily member 11"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-11-02T19:32:33+00:00"^^xsd:dateTime
schema:version 2564005398
wikibase:identifiers 24
wikibase:sitelinks 14
wikibase:statements 92
p:P10283 wd:statement/Q418934-0E0026CA-7719-484C-808F-652574918807
wd:statement/Q418934-F6FC5A66-7917-4418-86EB-8257E102E34B
p:P18 wd:statement/Q418934-F25BC315-B68C-4DDC-B9F9-34CBE1B1FA57
p:P2888 wd:statement/Q418934-4D020952-E1D8-4CC4-86B5-3922C63AC03D
p:P2892 wd:statement/Q418934-DB71C7C4-D027-4C78-8AFD-83BB03BF1EE5
p:P31 wd:statement/Q418934-2976C07E-0A63-407F-AF41-96557BBCCF64
p:P352 wd:statement/Q418934-B5FBA1E6-A2BB-45DE-9EAC-031EC31515CE
p:P361 wd:statement/Q418934-4FAD60EC-3508-427B-8AF9-8036972F883D
wd:statement/Q418934-7FEF5026-7A21-4D44-9F22-AAEF9159AD6D
wd:statement/Q418934-E4D65367-4B96-4E2E-A8A8-F17DD7042BF2
p:P486 wd:statement/Q418934-A0C79183-8362-41AF-B9F0-48C0B2E8A49B
p:P527 wd:statement/Q418934-BA29B904-A653-4F5D-BEE1-046E4A308EAD
p:P6366 wd:statement/Q418934-1340341E-5DD4-44DA-B1FF-19C63C4D9458
wd:statement/Q418934-4A2B2169-D6EA-4F78-B9AA-9C3F54016848
wd:statement/Q418934-DA7A9A58-0F9B-4505-B7F5-411BAC019175
p:P637 wd:statement/Q418934-6644FD28-543A-4A17-93D7-E838C41F4353
wd:statement/Q418934-A74E9070-0729-4A4B-8E30-AAD11F42C7B4
wd:statement/Q418934-A8B312DC-FDD9-432E-B80E-5153D08D914D
wd:statement/Q418934-CBB11A5B-C847-44B7-A8EA-5CB7CEA908BF
wd:statement/Q418934-DCF262B3-995A-4E6D-93D5-EE5FC55BA412
p:P638 wd:statement/Q418934-4A405B5F-D2EC-47AD-B796-B9172976EBE0
wd:statement/Q418934-DE3AB02C-6056-45BB-9361-2A3C83A9EC5C
p:P646 wd:statement/Q418934-E1FF4886-58A0-4B86-A57F-2F2B1B5AAF65
p:P672 wd:statement/Q418934-47090475-401c-03b0-3990-b5d7efc7a1dc
wd:statement/Q418934-cef60d41-40f9-85a5-da1b-4ff11a7ced04
wd:statement/Q418934-f1ba7cc9-43a6-5b9a-d206-0be9b45d6685
p:P680 wd:statement/Q418934-4BF13E0B-6DF2-4015-AA23-6B44BC563B20
wd:statement/Q418934-A569A1A2-2DEE-46E1-AF27-64DDBC4E27ED
wd:statement/Q418934-A754167A-1F2E-49AA-8F99-F7BB4313FDE4
wd:statement/Q418934-EB542934-03E5-41B0-BFDA-C85E228AE9C9
p:P681 wd:statement/Q418934-28285267-BAC6-4D7D-A425-233D85355EF6
wd:statement/Q418934-4EB31EA9-450F-4571-87EF-88F2AB6E7FF1
wd:statement/Q418934-62CC80B5-C8AE-4B9D-A11F-ED452558C4E5
wd:statement/Q418934-63066A0B-B3F0-41A4-8576-D1B4A8824F05
wd:statement/Q418934-7DE0F696-F14B-4816-872B-7D0F97903A97
wd:statement/Q418934-F220AA53-6EEB-46B8-B442-6A7818603227
wd:statement/Q418934-F98C22F1-8D11-4CC9-9924-80BB76D3E4C9
p:P682 wd:statement/Q418934-00C9D170-C71C-4410-81A1-D212222FA95B
wd:statement/Q418934-00E2E7EF-893C-45CB-BB9F-54AC08878786
wd:statement/Q418934-020D8ED4-2659-4EC1-877D-446E89B26EA3
wd:statement/Q418934-05DAE3B7-2F08-403E-8609-F9510BCA769A
wd:statement/Q418934-0634055F-D755-49D5-9365-5C01AF47936D
wd:statement/Q418934-0896D29D-BE95-4D36-BB10-29142DFD042D
wd:statement/Q418934-0DEC5FED-4522-4143-9D50-6494D4FCB21E
wd:statement/Q418934-1FD8DAAA-B23A-4E10-A438-04FF2004E9AF
wd:statement/Q418934-27D5AD2C-A460-44BB-919F-0917295402B5
wd:statement/Q418934-2E3803D1-9AD4-4D96-BF06-330863622BE2
wd:statement/Q418934-337C7907-8BC5-441F-9F0A-C0A544828C05
wd:statement/Q418934-3734F691-FC1F-466C-AD54-6920D2C06076
wd:statement/Q418934-3BA6EDC1-0BB2-42BE-BFF9-6F80DEACA42D
wd:statement/Q418934-41B5732D-893E-429C-90F0-F42A6DB7B96C
wd:statement/Q418934-450C8ABE-72EE-47AE-8D48-63A247800DCC
wd:statement/Q418934-48604912-3F19-452B-A17D-DA3BB746C338
wd:statement/Q418934-4D2E858F-74ED-4930-B41F-6E3FDEEC59A5
wd:statement/Q418934-525947AC-387A-4259-A22E-E1ACF9A11D84
wd:statement/Q418934-5AA05003-D568-47B4-BC21-D722DD48D5F4
wd:statement/Q418934-5F34AA72-2B9E-4300-B5C6-37C8147E7279
wd:statement/Q418934-6FC2CE77-6AA4-4BFF-85D4-A8AE5420A6FE
wd:statement/Q418934-70084208-4E65-4ED6-8A9D-2A8CFDAE87F9
wd:statement/Q418934-79D19495-EFDA-4EE4-B8ED-769BD6233B0D
wd:statement/Q418934-7B70BD57-165C-4527-B624-DF543B4C8BA4
wd:statement/Q418934-7D361015-6B84-400A-AA79-10B7D4AE0FFE
wd:statement/Q418934-822588C8-51C4-44A1-BF33-59627756D9E5
wd:statement/Q418934-869EE2F2-49C5-41FE-822D-99174DFA96FB
wd:statement/Q418934-8F92FCF0-8A30-4F31-A1AF-11EDB4BE39AE
wd:statement/Q418934-96920950-C2CA-4AA5-A625-44695BB9900B
wd:statement/Q418934-973087D1-1C4C-419F-B16B-3FE9F0ED7225
wd:statement/Q418934-9927151F-D7FE-4CFE-BDA6-B26A030D9BF0
wd:statement/Q418934-9BD5A794-0D70-499A-8E81-FC214C8A2A8C
wd:statement/Q418934-9E2414F4-0755-4A4A-AC4C-1A4913E8A46E
wd:statement/Q418934-A1D3D30A-5838-4E80-BE04-DA1020305887
wd:statement/Q418934-AB2E3C86-154F-424E-B66B-EEFDD7DC9754
wd:statement/Q418934-AEB17A04-276E-42E1-9E21-AF12877E3E4B
wd:statement/Q418934-B53F6A26-5FCD-4A31-91F1-DBED67E344B7
wd:statement/Q418934-C8E7982E-A7A0-4527-800D-2BB90DD2B35B
wd:statement/Q418934-CB641823-CDD3-4751-A161-CE43E37900E7
wd:statement/Q418934-CDB874FB-225D-45C9-916D-7C1DE287566D
wd:statement/Q418934-CF8F3F60-7E44-468B-AA0E-12FE561839B9
wd:statement/Q418934-D1667F5D-C74C-4B56-8561-B479A3E98D5A
wd:statement/Q418934-D53F5EE2-0E15-4DA0-8C39-549B5BFE7A49
wd:statement/Q418934-F39ECA6D-1EBB-4873-9B6E-CE650B6A1A80
wd:statement/Q418934-F50167A0-2D27-4E02-ACCE-8877A0B75951
wd:statement/Q418934-F54B495B-F128-4A65-8EAE-C268731FD43C
wd:statement/Q418934-FDBAD71D-F6A0-47F5-ABCE-F887108EEE64
p:P692 wd:statement/Q418934-7685AF2C-DAD8-45F3-9FE3-B8FADE7FD334
p:P702 wd:statement/Q418934-6F9F2F8E-E2A6-4AF1-86DD-A22BFFA926A1
p:P703 wd:statement/Q418934-DF8567B7-8241-4DD7-8C54-C82824A0C5CA
p:P705 wd:statement/Q418934-3566681E-99E9-405B-9CC2-0FEEC7AB4D71
wd:statement/Q418934-3B58BDCB-4668-4B9B-BDA3-192F52EE93D6
wd:statement/Q418934-49C16172-7F3F-4DC6-842E-1FBB842F875C
wd:statement/Q418934-9BAD9753-84F3-4847-9EC3-AC65DB2942EC
wd:statement/Q418934-CF328434-8719-4BF8-97A6-31B0ADB765D7
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/O14788>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D053245>
p:direct-normalized/P6366 <https://makg.org/entity/2779428903>
<https://makg.org/entity/2910053612>
<https://makg.org/entity/2910283315>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_003692>
<http://purl.uniprot.org/refseq/NP_143026>
<http://purl.uniprot.org/refseq/XP_011533582>
<http://purl.uniprot.org/refseq/XP_016876291>
<http://purl.uniprot.org/refseq/XP_016876292>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/3URF>
<https://rdf.wwpdb.org/pdb/5BNQ>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D12.644.276.374.750.562>
<http://id.nlm.nih.gov/mesh/D12.776.467.374.750.562>
<http://id.nlm.nih.gov/mesh/D23.529.374.750.562>
wdt:P10283 "C2779428903"
"C2909639871"
wdt:P18 <http://commons.wikimedia.org/wiki/Special:FilePath/Protein%20TNFSF11%20PDB%201s55.png>
wdt:P2888 <http://purl.uniprot.org/uniprot/O14788>
wdt:P2892 "C0666364"
wdt:P31 protein
wdt:P352 "O14788"
wdt:P361 Tumour necrosis factor ligand 10/11
Tumour necrosis factor-like domain superfamily
Tumour necrosis factor domain, protein family
wdt:P486 "D053245"
wdt:P527 Tumour necrosis factor domain
wdt:P6366 "2779428903"
"2910053612"
"2910283315"
wdt:P637 "NP_003692"
"NP_143026"
"XP_011533582"
"XP_016876291"
"XP_016876292"
wdt:P638 "3URF"
"5BNQ"
wdt:P646 "/m/0g4r43"
wdt:P672 "D12.644.276.374.750.562"
"D12.776.467.374.750.562"
"D23.529.374.750.562"
wdt:P680 cytokine activity
tumor necrosis factor receptor binding
tumor necrosis factor receptor superfamily binding
protein binding
wdt:P681 extracellular space
integral component of membrane
membrane
extracellular region
integral component of plasma membrane
plasma membrane
cytoplasm
wdt:P682 ossification
calcium ion homeostasis
positive regulation of gene expression
multicellular organism development
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling
positive regulation of transcription by RNA polymerase II
ERK1 and ERK2 cascade
monocyte chemotaxis
osteoclast differentiation
positive regulation of phosphorylation
positive regulation of bone resorption
protein homooligomerization
cytokine-mediated signaling pathway
animal organ morphogenesis
positive regulation of I-kappaB kinase/NF-kappaB signaling
tumor necrosis factor-mediated signaling pathway
positive regulation of DNA-binding transcription factor activity
positive regulation of MAP kinase activity
mammary gland alveolus development
positive regulation of T cell activation
positive regulation of JNK cascade
calcium-mediated signaling
regulation of signaling receptor activity
paracrine signaling
bone development
positive regulation of corticotropin-releasing hormone secretion
regulation of osteoclast differentiation
positive regulation of fever generation by positive regulation of prostaglandin secretion
TNFSF11-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
osteoclast proliferation
positive regulation of osteoclast differentiation
mammary gland epithelial cell proliferation
positive regulation of homotypic cell-cell adhesion
tooth eruption
osteoclast development
immune response
cell differentiation
positive regulation of intracellular signal transduction
positive regulation of osteoclast development
cellular response to leukemia inhibitory factor
regulation of actin binding
bone resorption
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20TNFSF11%20210643%20at%20fs.png>
wdt:P702 TNFSF11
wdt:P703 man
wdt:P705 "ENSP00000239849"
"ENSP00000351347"
"ENSP00000381775"
"ENSP00000384042"
"ENSP00000444913"
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