|
rdfs:label
|
"Lapatinib"@de
"Lapatinib"@es
"Lapatinib"@id
"Lapatinib"@it
"Lapatinib"@sh
"Lapatinib"@sr
"Lapatinib"@vi
"lapatinib"@en
"lapatinib"@fr
"lapatinib"@nl
"lapatinib"@pt
"lapatinib"@sl
"lapatinibum"@la
"lapatynib"@pl
"лапатиниб"@ru
"лапатиніб"@uk
"לפטיניב"@he
"لاباتينيب"@ar
"ଲାପାଟିନିବ"@or
"ラパチニブ"@ja
"拉帕替尼"@zh
"拉帕替尼"@zh-cn
"拉帕替尼"@zh-hans
"拉帕替尼"@zh-hant
"拉帕替尼"@zh-hk
"拉帕替尼"@zh-sg
"拉帕替尼"@zh-tw
|
|
skos:altLabel
|
"FMM"@en
"GW 572016"@en
"GW572016"@en
"LAP016"@en
"Lapatinib"@ru
"Lapatinib"@zh
"N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine"@en
"N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furanyl]-4-quinazolinamine"@en
"Tykerb"@de
"Tykerb"@es
"Tykerb"@pt
"Tykerb"@ru
"Tykerb"@zh
"Tyverb"@es
"Tyverb"@ru
"Тайверб"@ru
"Тайверб"@uk
"Тайкерб"@ru
|
|
schema:description
|
"Arzneistoff"@de
"cheemesch Verbindung"@lb
"chemical compound"@en
"chemical compound"@en-ca
"chemical compound"@en-gb
"chemická sloučenina"@cs
"chemická zlúčenina"@sk
"chemiese verbinding"@af
"chemische Verbindung"@de-ch
"chemische verbinding"@nl
"component quimic"@oc
"compositum chemicum"@la
"compost químic"@ca
"composto químico"@gl
"composto químico"@pt
"composto químico"@pt-br
"compuesto quimico"@an
"compuesto químico"@es
"compuestu químicu"@ast
"compus chimic"@ro
"farmaco"@it
"kemia kombinaĵo"@eo
"kemiallinen yhdiste"@fi
"kemisk forbindelse"@da
"kimyasal bileşik"@tr
"kjemisk forbindelse"@nb
"kjemisk sambinding"@nn
"komponim kimik"@sq
"konposatu kimiko"@eu
"médicament"@fr
"senyawa kimia"@id
"związek chemiczny"@pl
"ķīmisks savienojums"@lv
"хемиско соединение"@mk
"химическое соединение"@ru
"інгібітор протеїнкінази"@uk
"քիմիական միացություն"@hy
"תרכובת"@he
"مركب كيميائي"@ar
"کیٖمیٲیی مُرَکَب"@ks
"রাসায়নিক যৌগ"@bn
"രാസസംയുക്തം"@ml
|
|
schema:dateModified
|
"2026-06-19T13:19:35+00:00"^^xsd:dateTime
|
|
schema:version
|
2507904029
|
|
wikibase:identifiers
|
45
|
|
wikibase:sitelinks
|
19
|
|
wikibase:statements
|
73
|
|
p:P10245
|
wd:statement/Q420323-ad6cf24f-4718-2dd0-592a-435986b35aae
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|
p:P10283
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|
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|
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|
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|
p:P11198
|
wd:statement/Q420323-AD2073C3-ED2F-48A0-B703-06F0DFA1164A
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|
p:P11199
|
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|
p:P117
|
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|
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|
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|
wd:statement/Q420323-1D7ADB95-2410-4010-809C-8FC99567CC0C
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|
p:P1579
|
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|
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|
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|
p:P2062
|
wd:statement/Q420323-3312FFF7-7143-4BEA-A7B4-D85E3F12A2EE
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|
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|
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p:P235
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p:P267
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wd:statement/Q420323-2137E227-08C9-4097-99D9-66BB9A90B2A6
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p:P274
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wd:statement/Q420323-93CA8132-2E9E-4FF1-AA05-3307D89AB995
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p:P279
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p:P2868
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wd:statement/Q420323-9889611B-30AA-4E07-B37B-B11EABDF9095
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p:P2877
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p:P2892
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p:P31
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p:P3117
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p:P3345
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wd:statement/Q420323-4B22202D-B3C0-4DC1-85F5-36FE1C2027C9
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p:P3350
|
wd:statement/Q420323-56e4b493-408a-fc72-cc5b-19696e13e3e5
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p:P3489
|
wd:statement/Q420323-AB81C7B3-C09B-4D84-831D-A05064DD1A79
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|
wd:statement/Q420323-FF1A96DC-4209-48F9-8F0D-079EA38B831D
|
|
p:P3493
|
wd:statement/Q420323-CFCEF069-E1F9-4B1C-952F-12E3C38D31B0
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|
p:P361
|
wd:statement/Q420323-DF6AA3E2-B48E-4523-8C4E-47846EA73CA0
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|
p:P3636
|
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|
p:P366
|
wd:statement/Q420323-9B6BFEB4-AA03-4ED9-9C5A-ED3C2EA671D8
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|
p:P373
|
wd:statement/Q420323-7BBE4970-91B3-4EB5-8454-1C2BFA9E9A72
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|
p:P3780
|
wd:statement/Q420323-8C4A22C9-2683-47F2-B14D-A64E6E9CBA96
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|
wd:statement/Q420323-D83C9A99-259B-4546-BD4B-D071D5E08C55
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|
p:P4235
|
wd:statement/Q420323-7E5B718C-9414-4674-9DA2-4614C3576DCD
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|
p:P486
|
wd:statement/Q420323-E899F43B-5434-41EA-AA7E-6639A5C148D2
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p:P4964
|
wd:statement/Q420323-AFFADA5A-0E5B-45A0-BFB2-D36F43097034
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|
p:P527
|
wd:statement/Q420323-889F532C-138E-432D-A8F1-3A1AE7D3F004
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|
wd:statement/Q420323-93E8DF13-A028-4B17-B1F1-92D33CE2622E
|
|
p:P592
|
wd:statement/Q420323-92F7A30F-E2F7-4205-9538-D06F7AB4902E
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|
p:P595
|
wd:statement/Q420323-4842C7E9-2882-455A-BD7A-AF46CE0CBE96
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|
p:P6366
|
wd:statement/Q420323-D1A7D44D-7888-4868-97B9-D5A7211B0564
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|
p:P638
|
wd:statement/Q420323-1FCC0B29-5BC9-4348-B9E5-EDF5C041E901
|
|
wd:statement/Q420323-B0E48DB6-9772-4C0B-A16A-87F2B13BEAAA
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|
p:P646
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wd:statement/Q420323-0FB3817F-49F4-4AB0-A350-E04E2F1B4ACC
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|
p:P652
|
wd:statement/Q420323-13E6474D-C909-452F-A6B6-536AD35A61BA
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p:P661
|
wd:statement/Q420323-8AB8FDBA-4D85-4BF7-9167-BA7E71E4A4B9
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|
p:P662
|
wd:statement/Q420323-BB69CC3D-478C-4CD1-B811-E3B3199BCAFE
|
|
p:P665
|
wd:statement/Q420323-71AD179D-892A-4E7E-BAA7-A917169B0F04
|
|
p:P6689
|
wd:statement/Q420323-06CE744C-6036-4A9E-AEF4-B4103F444B7C
|
|
wd:statement/Q420323-09215000-2DE0-4CD2-929B-372190CCC5F2
|
|
wd:statement/Q420323-2AFE1C18-A2CC-4F17-90D5-AD2B4E1E576C
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|
wd:statement/Q420323-8252FCA6-B49A-4307-B03D-C3097293CB8A
|
|
wd:statement/Q420323-C0DF3DC9-542B-469B-9057-1BDED35393EF
|
|
wd:statement/Q420323-E8647471-BCF1-4CD6-89CC-95FC610ED346
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|
p:P672
|
wd:statement/Q420323-eb5f6396-461c-1904-b3ea-b6dd076f2455
|
|
p:P683
|
wd:statement/Q420323-CEEC8F19-5A24-4A78-9B08-62234248CDE8
|
|
p:P715
|
wd:statement/Q420323-1D42A66B-FF45-4B2E-8773-6E156512F0A4
|
|
p:P769
|
wd:statement/Q420323-2944F733-3E3F-4BC9-A121-7E38FF86A423
|
|
wd:statement/Q420323-65F00B75-6F0F-4B8D-82B3-F380F5889BB1
|
|
wd:statement/Q420323-7A5DE840-73E1-4706-A0FD-E31E926FFBE1
|
|
wd:statement/Q420323-7B140D62-37E6-4CD8-A59E-E5B4301BD306
|
|
wd:statement/Q420323-CAACC335-50E2-471C-AA25-652E89A69DB5
|
|
p:P7830
|
wd:statement/Q420323-C33194F1-CFA9-4249-87A3-8309852B3B74
|
|
p:P8026
|
wd:statement/Q420323-8568AFA4-5DA7-4AC2-B0E1-F6B803B949F0
|
|
p:P8494
|
wd:statement/Q420323-F612C5B1-2E2C-422C-BA74-CC40C2C40D94
|
|
p:P9272
|
wd:statement/Q420323-0E2C29F8-5A53-4145-A391-11B693C63259
|
|
p:direct-normalized/P2115
|
<http://purl.bioontology.org/ontology/NDFRT/N0000176088>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/D000077341>
|
|
p:direct-normalized/P592
|
<http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL554>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/2777329042>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1XKK>
|
|
<https://rdf.wwpdb.org/pdb/3BBT>
|
|
p:direct-normalized/P661
|
<http://rdf.chemspider.com/181006>
|
|
p:direct-normalized/P662
|
<http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID208908>
|
|
p:direct-normalized/P665
|
<http://www.kegg.jp/entry/D04024>
|
|
p:direct-normalized/P672
|
<http://id.nlm.nih.gov/mesh/D03.633.100.786.516>
|
|
p:direct-normalized/P683
|
<http://purl.obolibrary.org/obo/CHEBI_49603>
|
|
wdt:P10245
|
"a607055"
|
|
wdt:P10283
|
"C2777329042"
|
|
wdt:P11089
|
"608060"
|
|
wdt:P11143
|
"Lapatinib"
|
|
wdt:P11198
|
"1548"
|
|
wdt:P11199
|
"PD003505"
|
|
wdt:P117
|
<http://commons.wikimedia.org/wiki/Special:FilePath/Lapatinib.svg>
|
|
wdt:P129
|
Erb-b2 receptor tyrosine kinase 2
|
|
epidermal growth factor receptor
|
|
wdt:P1579
|
"10502247"
|
|
wdt:P2057
|
"HMDB0015388"
|
|
wdt:P2062
|
"8209"
|
|
wdt:P2067
|
580.135^^xsd:decimal
|
|
wdt:P2115
|
"N0000176088"
|
|
wdt:P2175
|
rare breast tumor
|
|
wdt:P2275
|
"lapatinib"@en
|
|
wdt:P231
|
"231277-92-2"
|
|
wdt:P233
|
"CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl"
|
|
wdt:P234
|
"InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)"
|
|
wdt:P235
|
"BCFGMOOMADDAQU-UHFFFAOYSA-N"
|
|
wdt:P267
|
"L01XE07"
|
|
wdt:P274
|
"C₂₉H₂₆ClFN₄O₄S"
|
|
wdt:P279
|
heterocyclic compound
|
|
wdt:P2868
|
antineoplastic
|
|
protein kinase inhibitors
|
|
wdt:P2877
|
"8100"
|
|
wdt:P2892
|
"C1506770"
|
|
wdt:P31
|
type of chemical entity
|
|
wdt:P3117
|
"DTXSID7046675"
|
|
wdt:P3345
|
"480167"
|
|
wdt:P3350
|
"8378"
|
|
wdt:P3489
|
US pregnancy category D
|
|
Australian pregnancy category D
|
|
wdt:P3493
|
boxed warning
|
|
wdt:P361
|
response to lapatinib
|
|
wdt:P3636
|
"FMM"
|
|
wdt:P366
|
medication
|
|
wdt:P373
|
"Lapatinib"
|
|
wdt:P3780
|
Tyverb
|
|
Tykerb
|
|
wdt:P4235
|
"lapatinib"
|
|
wdt:P486
|
"D000077341"
|
|
wdt:P4964
|
"splash10-0ab9-0649800000-87742edfe3489dab4ac8"
|
|
wdt:P527
|
carbon
|
|
oxygen
|
|
wdt:P592
|
"CHEMBL554"
|
|
wdt:P595
|
"5692"
|
|
wdt:P6366
|
"2777329042"
|
|
wdt:P638
|
"1XKK"
|
|
"3BBT"
|
|
wdt:P646
|
"/m/0cgbt7"
|
|
wdt:P652
|
"0VUA21238F"
|
|
wdt:P661
|
"181006"
|
|
wdt:P662
|
"208908"
|
|
wdt:P665
|
"D04024"
|
|
wdt:P6689
|
"MSBNK-Athens_Univ-AU252501"
|
|
"MSBNK-Athens_Univ-AU252502"
|
|
"MSBNK-Athens_Univ-AU252503"
|
|
"MSBNK-Athens_Univ-AU252504"
|
|
"MSBNK-Athens_Univ-AU252505"
|
|
"MSBNK-Athens_Univ-AU252506"
|
|
wdt:P672
|
"D03.633.100.786.516"
|
|
wdt:P683
|
"49603"
|
|
wdt:P715
|
"DB01259"
|
|
wdt:P769
|
clarithromycin
|
|
erythromycin
|
|
voriconazole
|
|
crizotinib
|
|
posaconazole
|
|
wdt:P7830
|
"Lapatinib"
|
|
wdt:P8026
|
LiverTox toxicity likelihood category B
|
|
wdt:P8494
|
"DTXCID5026675"
|
|
wdt:P9272
|
"57625"
|
