SHMARQL

signal transducer and activator of transcription 3

<http://www.wikidata.org/entity/Q4210010>

mammalian protein found in Homo sapiens
rdfs:label
"signal transducer and activator of transcription 3"@en
skos:altLabel "DNA-binding protein APRF"@en
"STAT3"@en
"STAT3 Transcription Factor"@en
"acute-phase response factor"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2025-07-23T21:51:17+00:00"^^xsd:dateTime
schema:version 2383308559
wikibase:identifiers 28
wikibase:sitelinks 0
wikibase:statements 176
p:P2888 wd:statement/Q4210010-3DA9EFE7-DEBB-49A9-B26D-B2C68C7F8AFB
p:P2892 wd:statement/Q4210010-FD1A2DE2-3CFF-4644-AB17-64202EE655D5
p:P31 wd:statement/Q4210010-C634B738-EE69-4D33-8B99-689B22FAFA2C
p:P352 wd:statement/Q4210010-73F9C10E-61D6-478F-99F4-799C232A723A
p:P361 wd:statement/Q4210010-6F58F18A-80C4-4D22-8292-336020840489
wd:statement/Q4210010-73C32C02-F8E9-484F-915D-D41C2B0C556F
wd:statement/Q4210010-7A92B075-FC0B-4780-9927-07A78F67B3A9
wd:statement/Q4210010-980A7BAC-AEBF-4B77-AA9F-3CF6C2B7F163
wd:statement/Q4210010-A6954B46-FC3F-4A73-836A-BECD0BF48192
wd:statement/Q4210010-B3B87ABE-5FD4-4071-8491-E16ABDE89FE2
wd:statement/Q4210010-B5D7ED47-7FF6-4641-8519-DFADCCE0E2A7
wd:statement/Q4210010-BE5159AA-1CEC-4B22-8D94-655E3F76246C
wd:statement/Q4210010-BF7CF7F0-F3FF-4662-AE68-F3606B1F06C8
wd:statement/Q4210010-E68C18ED-5AF5-4A8E-BDE5-A4DE5ADFE1EE
wd:statement/Q4210010-F0DFF441-3AA8-4F3A-8B34-D152C56838D7
p:P486 wd:statement/Q4210010-FC3AADD2-D035-4BEF-A250-C9275C2B0EB4
p:P527 wd:statement/Q4210010-45AAA4AD-48BA-4054-BA63-80FA899BD9B8
wd:statement/Q4210010-8D4A3105-6F81-4BE4-8B14-FCB72825DFE1
wd:statement/Q4210010-D371FB00-12BF-4B08-874A-EEF9F18BB02A
wd:statement/Q4210010-DA495531-446F-4EF5-93DF-AB3BF5984CBB
wd:statement/Q4210010-E89EF20B-7D76-4954-8DA3-9C6602289A79
p:P637 wd:statement/Q4210010-10C5ABB2-C263-432F-A9F0-709E6DB6AA61
wd:statement/Q4210010-1F1FA7EE-4BFE-408C-B1E5-E76AE193319B
wd:statement/Q4210010-3B3039A4-6DBD-49FD-882D-F4206DC28A2E
wd:statement/Q4210010-54A1EC9B-1851-422A-8586-482FF7F8CDD7
wd:statement/Q4210010-572AE569-A7FB-4CAD-B850-DBCA53C34A5C
wd:statement/Q4210010-57B8D561-6B6A-45E1-B8F8-3876B8C49440
wd:statement/Q4210010-76E84FED-E9D6-4DF4-A457-F33C9A20AC2E
wd:statement/Q4210010-7EA41ED6-7911-47D7-AB07-720048E2E523
wd:statement/Q4210010-9A99B9D0-4F82-4F24-A0A5-751A3661F25F
wd:statement/Q4210010-9F0B2D45-7CED-4BAA-B85E-76A9FA1C096F
wd:statement/Q4210010-AAD11518-696D-4FC3-B4C6-B7A8F5A002DF
wd:statement/Q4210010-C2AF2DE7-E645-4E6F-8D4F-B3FC8C5469A5
wd:statement/Q4210010-CEB9A157-DBEE-463D-B3A8-950CFB9EDCEA
p:P638 wd:statement/Q4210010-BEAFCF50-62E6-4ABF-B23D-92F7396E6860
p:P646 wd:statement/Q4210010-57EF1443-D250-40FB-83B4-AB488E75AF8A
p:P672 wd:statement/Q4210010-491416b1-4c84-a364-5919-06dde8fdab7c
wd:statement/Q4210010-4fce1131-4be4-97d2-8b17-3704784bc5b1
wd:statement/Q4210010-d2a780aa-4fea-339e-1293-d70f01f10306
wd:statement/Q4210010-f01e77e4-4e43-b144-57e2-3c93d0fc4d5b
p:P680 wd:statement/Q4210010-02AD3981-9C13-4CFB-AADA-08C2560D365E
wd:statement/Q4210010-0E42420C-C575-43DD-A141-2086C0CD3A15
wd:statement/Q4210010-230CEB90-56A9-4C75-BFB9-D749C3DF5990
wd:statement/Q4210010-36718471-470B-4316-8111-C8C613BC577D
wd:statement/Q4210010-45D13560-811E-4F34-B471-F73AADA7155A
wd:statement/Q4210010-4F7C2CB4-E3C5-4BDE-8A03-E0413C1905B4
wd:statement/Q4210010-5919B378-3E3A-472A-AE94-27B72AE74189
wd:statement/Q4210010-6BAFA582-BEA2-4ACB-A0A1-9CB57B7797A8
wd:statement/Q4210010-6E45E519-2BB1-419E-B5B1-48CD46771607
wd:statement/Q4210010-7C5DC7D5-C62E-436A-821A-047106873481
wd:statement/Q4210010-7DE5ABE3-5B2A-4210-ADB5-492C7DC3C5C6
wd:statement/Q4210010-81C9C2F9-7FD6-4C80-9BFD-ADBCAB93868C
wd:statement/Q4210010-825CD061-7AC2-4DCC-B631-157080464BDF
wd:statement/Q4210010-9057561B-5B75-4411-9A5B-C47EFBFBF4B0
wd:statement/Q4210010-92A65AC2-61DB-4E07-83A6-A24DBD49EFCD
wd:statement/Q4210010-A2E17EB7-B133-408F-9656-1108398FFE9B
wd:statement/Q4210010-A84CF4C1-E600-446B-B549-95BD835395DD
wd:statement/Q4210010-AC3BCE54-FBC4-483F-999A-B3D3AA6E69BD
wd:statement/Q4210010-BA8BE518-4FBF-4D48-A1F4-1868975C3AB8
wd:statement/Q4210010-DEE24969-9282-4BF2-BBEB-46C088EBDA6D
wd:statement/Q4210010-E40015FD-D334-4A7E-909D-739AB3B7E303
wd:statement/Q4210010-F55BA68E-821C-40C2-AA4A-B9C934F6DE24
p:P681 wd:statement/Q4210010-04E64374-488B-4FBD-BDA6-58FCF8F2FD11
wd:statement/Q4210010-36B5BE9C-74FA-415E-9864-CDE360923394
wd:statement/Q4210010-36F629CE-2242-461B-B34C-A4ACD644022B
wd:statement/Q4210010-4B38B3FE-63F1-4FDB-93FD-F06229715C70
wd:statement/Q4210010-806C467A-DF3C-4D22-82D7-169CF780E74C
wd:statement/Q4210010-8760DBF4-6A45-4E6D-9FB0-E070F29F17E5
wd:statement/Q4210010-9BFF6094-E25B-4DC8-90DA-FA0731D1FD61
wd:statement/Q4210010-B04746B2-E1B8-47E3-B098-811AC70E9E16
wd:statement/Q4210010-C26E7563-FF25-415D-B81E-EE9C87C4B2C9
wd:statement/Q4210010-D94CB8F3-A73F-4CE2-9B22-40A40075BF4A
wd:statement/Q4210010-DB4B488F-420F-4C24-BF28-85A84CF5EBD8
wd:statement/Q4210010-E29ACAE7-1D06-471E-A7B5-469CEFD9F04D
wd:statement/Q4210010-E840F461-5463-43DF-86B1-DF2D73D7E160
wd:statement/Q4210010-EBA691C1-08FC-4B23-835C-04BB2E1E4D1B
p:P682 wd:statement/Q4210010-01AF7F18-4DB2-4FC1-832A-3C149AD70CA3
wd:statement/Q4210010-0BB8979E-F38E-47FA-946B-104C71117C12
wd:statement/Q4210010-14BBF7BA-8BA8-414B-AC31-C03CF098E7F6
wd:statement/Q4210010-1689E4F2-EE1D-4A3F-93C2-A5469BCFE0F3
wd:statement/Q4210010-19638A82-A8A9-4253-AF28-C01DBE94C780
wd:statement/Q4210010-1A63E831-31C5-421F-AA98-5863A6132CC1
wd:statement/Q4210010-1B38E541-F27E-4665-B8F7-6BE5A3817F79
wd:statement/Q4210010-1BFBBF66-DA88-4F8B-B490-E1109501F09F
wd:statement/Q4210010-1CC1C18C-7986-4013-B834-0ACC3456952B
wd:statement/Q4210010-20C5700E-42F4-48A6-91FA-376ABDB3BE4A
wd:statement/Q4210010-20F9A148-9821-4CC5-B7C8-E1ED95CC7143
wd:statement/Q4210010-2266647C-0233-4D48-A8D9-583480E63C00
wd:statement/Q4210010-25E92886-D0B3-4E06-8032-BA1F5D7FD2DB
wd:statement/Q4210010-2752ADB1-DF9E-4871-891B-E9DC5EF6054E
wd:statement/Q4210010-29571B0E-2697-4D1B-B272-6893005D79C1
wd:statement/Q4210010-2B804A74-3BD9-436D-AC5C-2785554EC846
wd:statement/Q4210010-2BB03C68-B773-4D8B-9F57-CE396778EF68
wd:statement/Q4210010-32D2E9C2-B9D1-42F0-859A-ED2DC94AE0F9
wd:statement/Q4210010-32DD2DEB-9841-4CE4-AD54-B3775812E8CB
wd:statement/Q4210010-34CE275A-EFEE-40E0-B120-588BD4FB2736
wd:statement/Q4210010-36480F89-06A1-408E-AAEF-2376862CAFB0
wd:statement/Q4210010-3B6839EE-89A8-4558-BCB9-44BF807A0DA1
wd:statement/Q4210010-3D2BC1A9-25E5-4E3C-9C1E-3C3BF6F6C105
wd:statement/Q4210010-3DC2E5F6-8540-4528-AD35-BDFABA77BDD7
wd:statement/Q4210010-3F256B95-63F4-460F-9BC4-62C07F24E0A3
wd:statement/Q4210010-401760DE-ACCC-4E63-B2FF-DAB3238E34DD
wd:statement/Q4210010-415B496D-C505-4349-8A86-F5480487B54F
wd:statement/Q4210010-41A62497-BD2F-4A46-996B-A70EB89240BD
wd:statement/Q4210010-456779AA-C40B-45AD-9AE6-1C034C216061
wd:statement/Q4210010-52DF6997-C073-485A-8608-F581C15677AF
wd:statement/Q4210010-59263AA4-3213-434E-83DA-F10A8AEFB3CB
wd:statement/Q4210010-6012B660-12C6-436D-A7A1-0B55A4C2686A
wd:statement/Q4210010-6097AD02-0596-42BF-9590-08A54143E7A2
wd:statement/Q4210010-6351801E-4611-4CB7-8785-DC2BDBAD6AC7
wd:statement/Q4210010-65DA0C0D-3827-4087-90A1-76F4704B2674
wd:statement/Q4210010-660BE3AE-8493-4E81-87B0-EE0F852C8037
wd:statement/Q4210010-668A4505-4478-41A8-9CBD-D4CA28B9A404
wd:statement/Q4210010-69E1DA45-A878-492F-B6C9-38FBBF03AE15
wd:statement/Q4210010-6DF936E3-8D62-4D76-8B1A-F36F48118CF0
wd:statement/Q4210010-710684B4-7F79-4949-B8A6-F4C45653F082
wd:statement/Q4210010-74F7771E-DDE6-4AC0-806C-99058D1F40AA
wd:statement/Q4210010-7520382F-0B66-49B9-81E0-2A496262FF31
wd:statement/Q4210010-76CEA012-7E03-4850-933E-41F33445A55C
wd:statement/Q4210010-77C11D07-E332-4906-A5E1-51315333C0C5
wd:statement/Q4210010-7AA932AB-C3C2-4E35-8D0C-476F9589A860
wd:statement/Q4210010-7B084D00-0DB5-4598-A2FE-0FC786F0FFB0
wd:statement/Q4210010-83003920-6706-4EDC-B18D-CD9C9D9FD225
wd:statement/Q4210010-8692E3DA-0552-4CE1-8C8D-957BF279AE92
wd:statement/Q4210010-880F4198-0997-4AF0-BB5B-D1F79BC1E41F
wd:statement/Q4210010-8A031FF2-D38C-42DF-8EE0-9D2FD5EA6B6E
wd:statement/Q4210010-90D9457D-28AF-46B7-A290-4DC16416EBB1
wd:statement/Q4210010-9A3893FE-0A50-4973-A8A0-D981B867447C
wd:statement/Q4210010-9AF7337F-830B-42D2-A72C-F5149218B0CC
wd:statement/Q4210010-9B9E2226-E183-4B47-ADB5-30C969E65CDC
wd:statement/Q4210010-9E7281D4-1FAF-4F60-BC50-5091D43170D3
wd:statement/Q4210010-9E7FBD87-FEEE-4BEF-B2C1-9F01EA02043C
wd:statement/Q4210010-A0D4D2BA-E90F-42DA-B693-30F643B8B832
wd:statement/Q4210010-A1E459E4-D8D1-4C1B-B75F-6ACFAC4DA4A9
wd:statement/Q4210010-A524FBD9-B906-4EA2-BA2D-67635BE664D3
wd:statement/Q4210010-A861BA19-51D5-4562-9F3A-81AA8151C689
wd:statement/Q4210010-A8C77A24-2A65-4CEB-82C3-4770A2DF0FE4
wd:statement/Q4210010-A8DAC5BA-39A3-4BCC-AE84-B364AC7FAA45
wd:statement/Q4210010-AF06F9FF-4620-4F90-9647-836DDC64B26B
wd:statement/Q4210010-B0BBE4DF-C112-42FD-BD68-A2CF6445C2FD
wd:statement/Q4210010-B1CEFC8C-C8C3-49A1-8E06-0498BC104236
wd:statement/Q4210010-B7D1A40F-E8C8-4A03-A0DA-2755EEDD9ADF
wd:statement/Q4210010-C470FBC1-7E3E-4013-B479-FB5E4EBE6138
wd:statement/Q4210010-C485CFE9-EA60-4DEB-9665-6140CE00F70D
wd:statement/Q4210010-C5922CF9-DCDE-4002-A7DD-DD2281B71205
wd:statement/Q4210010-C9D0F54E-14F7-4399-8CFB-031984E41454
wd:statement/Q4210010-CB7BBD06-0D40-4DA3-B310-D1C50105217D
wd:statement/Q4210010-CCFD4C69-919B-4845-8A68-96157A0E366C
wd:statement/Q4210010-D0D25A55-6F04-4762-96E5-B64DE11F8144
wd:statement/Q4210010-D613C4FE-B460-4B3C-9115-7B3FF491514F
wd:statement/Q4210010-D86BA50E-58F3-4E93-81CF-2BA6D428661B
wd:statement/Q4210010-D96BF6BF-EAA2-4045-9505-2C6D8175272B
wd:statement/Q4210010-DE31A983-4F0F-4CDF-927D-4B1991646A14
wd:statement/Q4210010-E4079015-D725-4D0D-A6A9-8BE457AC7BFB
wd:statement/Q4210010-E5346C58-7506-4CE2-9045-F61A7D4A8916
wd:statement/Q4210010-E77DEADC-037A-408A-85B0-2120FA7DC760
wd:statement/Q4210010-E926B85E-AAC9-4015-9F25-CF4D68E864EA
wd:statement/Q4210010-EF32F6C8-3ED0-458B-A64A-A3859E3DCEAB
wd:statement/Q4210010-F178E56B-59F1-4124-9E5A-9161AF2582CD
wd:statement/Q4210010-F382037E-6DBF-4E84-B9F8-6DB5A707A2B1
wd:statement/Q4210010-F4039CE9-BF33-4F0D-98A2-891A201A3F06
wd:statement/Q4210010-F640F8DA-90A2-47AB-986F-98F2878A5C45
wd:statement/Q4210010-F91F0797-9BFA-41FC-AF71-D261C886108E
wd:statement/Q4210010-FC4F5FFF-92A6-42D8-9968-D314033FD3FE
wd:statement/Q4210010-FDEDEB96-00FC-4D23-99B6-AE3D47A9F6AD
wd:statement/Q4210010-FE429CEA-9C9A-4A32-ACC4-563A6D8648C6
wd:statement/Q4210010-FEACAD88-1F07-4140-8EE3-3C7B694E2318
p:P692 wd:statement/Q4210010-D1054958-4C1A-44E0-BAB8-D610BDCBADB7
p:P702 wd:statement/Q4210010-84EC8E86-17D4-483E-A823-164A81EA3597
p:P703 wd:statement/Q4210010-CB07E49F-8134-4971-A166-0F937961DDAB
p:P705 wd:statement/Q4210010-06275C93-04EA-46D7-ADFB-8A0E81FAFA7F
wd:statement/Q4210010-159C34FE-1ECD-4E36-9145-6711E0D61F2B
wd:statement/Q4210010-500F9270-96A4-4B96-BD63-953C4F3DDCDA
wd:statement/Q4210010-8491ADC8-E0AC-4AD8-9232-9C5256B8E7EF
wd:statement/Q4210010-B085D224-7696-42E9-AA35-5FA48201867D
wd:statement/Q4210010-FD951E10-3B0D-4F32-BBEA-4406F00DF6ED
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P40763>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D050796>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_001356441>
<http://purl.uniprot.org/refseq/NP_001356442>
<http://purl.uniprot.org/refseq/NP_001356443>
<http://purl.uniprot.org/refseq/NP_001356445>
<http://purl.uniprot.org/refseq/NP_001356446>
<http://purl.uniprot.org/refseq/NP_001356447>
<http://purl.uniprot.org/refseq/NP_001356448>
<http://purl.uniprot.org/refseq/NP_001356449>
<http://purl.uniprot.org/refseq/NP_003141>
<http://purl.uniprot.org/refseq/NP_644805>
<http://purl.uniprot.org/refseq/NP_998827>
<http://purl.uniprot.org/refseq/XP_016880462>
<http://purl.uniprot.org/refseq/XP_024306664>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/5AX3>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D12.644.360.024.342.300>
<http://id.nlm.nih.gov/mesh/D12.776.157.057.186.300>
<http://id.nlm.nih.gov/mesh/D12.776.476.024.430.300>
<http://id.nlm.nih.gov/mesh/D12.776.930.840.300>
wdt:P2888 <http://purl.uniprot.org/uniprot/P40763>
wdt:P2892 "C0253050"
wdt:P31 protein
wdt:P352 "P40763"
wdt:P361 p53-like transcription factor, DNA-binding
STAT transcription factor, coiled coil
STAT transcription factor, DNA-binding, N-terminal
STAT transcription factor, N-terminal domain superfamily
SH2 domain superfamily
transcription factor STAT
STAT transcription factor, protein interaction, protein family
STAT transcription factor, DNA-binding domain, protein family
SH2 domain, protein family
STAT transcription factor, all-alpha domain, protein family
STAT3, SH2 domain, protein family
wdt:P486 "D050796"
wdt:P527 STAT transcription factor, protein interaction
STAT transcription factor, DNA-binding
SH2 domain
STAT transcription factor, all-alpha domain
STAT3, SH2 domain
wdt:P637 "NP_001356441"
"NP_001356442"
"NP_001356443"
"NP_001356445"
"NP_001356446"
"NP_001356447"
"NP_001356448"
"NP_001356449"
"NP_003141"
"NP_644805"
"NP_998827"
"XP_016880462"
"XP_024306664"
wdt:P638 "5AX3"
wdt:P646 "/m/02q3lnl"
wdt:P672 "D12.644.360.024.342.300"
"D12.776.157.057.186.300"
"D12.776.476.024.430.300"
"D12.776.930.840.300"
wdt:P680 DNA binding
identical protein binding
protein homodimerization activity
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
transcription factor binding
protein kinase binding
sequence-specific DNA binding
signal transducer activity
protein dimerization activity
protein phosphatase binding
DNA-binding transcription factor activity, RNA polymerase II-specific
nuclear receptor activity
chromatin DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
CCR5 chemokine receptor binding
glucocorticoid receptor binding
protein binding
wdt:P681 mitochondrial inner membrane
nucleoplasm
transcription regulator complex
RNA polymerase II transcription regulator complex
cytosol
glutamatergic synapse
plasma membrane
Schaffer collateral - CA1 synapse
mitochondrion
nucleus
postsynaptic density
cytoplasm
wdt:P682 nervous system development
regulation of mitochondrial membrane permeability
modulation of chemical synaptic transmission
negative regulation of cell population proliferation
negative regulation of apoptotic process
negative regulation of transcription by RNA polymerase II
regulation of transcription, DNA-templated
positive regulation of cell population proliferation
positive regulation of gene expression
response to estradiol
acute-phase response
positive regulation of cell migration
glucose homeostasis
positive regulation of NF-kappaB transcription factor activity
transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
regulation of cell population proliferation
regulation of cell cycle
inflammatory response
response to ethanol
negative regulation of cell death
regulation of multicellular organism growth
growth hormone receptor signaling pathway via JAK-STAT
eating behavior
response to peptide hormone
response to organic cyclic compound
defense response
leptin-mediated signaling pathway
regulation of transcription by RNA polymerase II
response to cytokine
response to organic substance
cellular response to leptin stimulus
cytokine-mediated signaling pathway
cellular response to cytokine stimulus
negative regulation of neuron death
negative regulation of autophagy
transcription by RNA polymerase II
somatic stem cell population maintenance
mRNA transcription by RNA polymerase II
stem cell population maintenance
cellular response to hormone stimulus
viral process
interleukin-6-mediated signaling pathway
positive regulation of angiogenesis
regulation of feeding behavior
intracellular receptor signaling pathway
astrocyte differentiation
protein import into nucleus
interleukin-7-mediated signaling pathway
receptor signaling pathway via JAK-STAT
cellular response to organic cyclic compound
temperature homeostasis
positive regulation of erythrocyte differentiation
growth hormone receptor signaling pathway
negative regulation of neuron migration
positive regulation of tyrosine phosphorylation of STAT protein
interleukin-27-mediated signaling pathway
eye photoreceptor cell differentiation
positive regulation of Notch signaling pathway
radial glial cell differentiation
sexual reproduction
cell population proliferation
T-helper 17 cell lineage commitment
negative regulation of glycolytic process
response to leptin
positive regulation of pri-miRNA transcription by RNA polymerase II
interleukin-23-mediated signaling pathway
positive regulation of ATP biosynthetic process
positive regulation of gene silencing by miRNA
miRNA-mediated gene silencing by inhibition of translation
negative regulation of stem cell differentiation
interleukin-15-mediated signaling pathway
interleukin-21-mediated signaling pathway
negative regulation of hydrogen peroxide biosynthetic process
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation
interleukin-9-mediated signaling pathway
energy homeostasis
interleukin-35-mediated signaling pathway
positive regulation of metalloendopeptidase activity
postsynapse to nucleus signaling pathway
phosphorylation
positive regulation of vascular endothelial cell proliferation
ageing
signal transduction
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20STAT3%20208991%20at%20fs.png>
wdt:P702 STAT3
wdt:P703 human beings
wdt:P705 "ENSP00000264657"
"ENSP00000373923"
"ENSP00000384943"
"ENSP00000467000"
"ENSP00000467173"
"ENSP00000467985"
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data from SPARQL profile: Wikidata