SHMARQL

everolimus

<http://www.wikidata.org/entity/Q421052>

chemical compound
rdfs:label
"everolimus"@en
skos:altLabel
"40-O-(2-hydroxyethyl)-rapamycin"@en
"42-O-(2-hydroxyethyl)rapamycin"@en
"RAD001"@en
"SDZ-RAD"@en
schema:description
"chemical compound"@en
schema:dateModified "2026-01-19T14:57:15+00:00"^^xsd:dateTime
schema:version 2456122657
wikibase:identifiers 38
wikibase:sitelinks 27
wikibase:statements 82
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wd:statement/Q421052-F315F9B2-CF31-4FBD-B2AD-A6DCD2452901
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p:P3345 wd:statement/Q421052-1C5FAB54-C5DD-4C23-8E86-8F6793C78FBD
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p:P3780 wd:statement/Q421052-126A8E20-2CA0-4452-B69B-3478BE1C3932
wd:statement/Q421052-C1EF5549-512C-4C80-8903-4BD19DF29A72
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p:P592 wd:statement/Q421052-0B91130D-F673-4D81-8C27-FFA4C39D2DEB
p:P595 wd:statement/Q421052-B1DA4976-BCAE-4302-95FB-1C52C1B7BDF0
p:P6366 wd:statement/Q421052-949D252A-374D-4EDE-9F3B-B5CECB9C87C1
p:P646 wd:statement/Q421052-46F8CE15-A590-4DC6-ADE3-278EE3B58AF1
p:P652 wd:statement/Q421052-AD8DC712-FEB1-40A7-9DD7-5727CEB573F9
p:P661 wd:statement/Q421052-39A7C8EF-E206-4DEC-88C5-119DE6C6CE01
p:P662 wd:statement/Q421052-5BB95CCD-CC8D-492D-B634-81A6DEC7498A
p:P665 wd:statement/Q421052-7A2A0CF6-D175-43C9-8543-B2E1ECB25D7E
p:P672 wd:statement/Q421052-a18aa500-4c6f-e493-6047-8c27e4f4962a
p:P683 wd:statement/Q421052-725E1B2C-7518-4205-8780-CC4EEA2DAF74
p:P715 wd:statement/Q421052-52F737D4-501D-41E1-80D0-42616EF8BA3E
p:P769 wd:statement/Q421052-E12DE2D7-4763-42B9-BF89-882C2589D129
p:P7830 wd:statement/Q421052-A6256715-F21A-4B50-8FE2-5BF7C2B1944E
p:P8026 wd:statement/Q421052-8850EBA2-C875-42CF-BA1B-6134A9700606
p:P8494 wd:statement/Q421052-861D8494-3344-4C37-9D46-58029905D815
p:P9272 wd:statement/Q421052-2452FFF5-532F-4132-AE00-2CCB9E7C8C6D
p:direct-normalized/P2115 <http://purl.bioontology.org/ontology/NDFRT/N0000178379>
p:direct-normalized/P4527 <http://data.parliament.uk/terms/418338>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D000068338>
p:direct-normalized/P592 <http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL1908360>
p:direct-normalized/P6366 <https://makg.org/entity/2779699572>
p:direct-normalized/P661 <http://rdf.chemspider.com/21106307>
p:direct-normalized/P662 <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6442177>
p:direct-normalized/P665 <http://www.kegg.jp/entry/D02714>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D02.540.505.760.500>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_68478>
wdt:P10245 "a609032"
wdt:P10283 "C2779699572"
wdt:P11089 "1077088"
wdt:P11143 "Everolimus"
wdt:P11198 "1118"
wdt:P11199 "PD004083"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Everolimus.svg>
wdt:P129 mechanistic target of rapamycin kinase
wdt:P2017 "C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC"
wdt:P2057 "HMDB0015529"
wdt:P2062 "8255"
wdt:P2067 957.581^^xsd:decimal
wdt:P2115 "N0000178379"
wdt:P2175 renal cell carcinoma
breast cancer
carcinoid tumor
neuroendocrine carcinoma
renal clear cell carcinoma
small intestine carcinoma
kidney angiomyolipoma
neuroendocrine tumor
lymphoma
diffuse large B-cell lymphoma
acute myeloid leukemia
kidney cancer
carcinoid syndrome
angiomyolipoma
low-grade astrocytoma
benign neoplasm of brain
tuberous sclerosis 1
islet cell carcinoma
wdt:P2275 "everolimus"@en
wdt:P231 "159351-69-6"
wdt:P232 "621-003-9"
wdt:P233 "CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC"
wdt:P234 "InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1"
wdt:P235 "HKVAMNSJSFKALM-GKUWKFKPSA-N"
wdt:P2566 "100.149.896"
wdt:P267 "L01XE10"
"L04AA18"
wdt:P274 "C₅₃H₈₃NO₁₄"
wdt:P279 LSM-4258
wdt:P2868 immunosuppressive drug
antineoplastic
xenobiotic-transporting ATPase inhibitor
protein kinase inhibitors
wdt:P2877 "4378"
wdt:P2892 "C0541315"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID0040599"
wdt:P3345 "141704"
wdt:P3350 "7863"
wdt:P3364 LSM-5313
wdt:P3489 US pregnancy category D
wdt:P3493 boxed warning
wdt:P366 medication
wdt:P373 "Everolimus"
wdt:P3780 Afinitor
Votubia
Zortress
wdt:P4235 "everolimus"
wdt:P4250 1.5^^xsd:decimal
wdt:P4527 "418338"
wdt:P486 "D000068338"
wdt:P527 carbon
wdt:P592 "CHEMBL1908360"
wdt:P595 "5889"
wdt:P6366 "2779699572"
wdt:P646 "/m/02m34c"
wdt:P652 "9HW64Q8G6G"
wdt:P661 "21106307"
wdt:P662 "6442177"
wdt:P665 "D02714"
wdt:P672 "D02.540.505.760.500"
wdt:P683 "68478"
wdt:P715 "DB01590"
wdt:P769 idelalisib
wdt:P7830 "Everolimus"
wdt:P8026 LiverTox toxicity likelihood category E*
wdt:P8494 "DTXCID8020599"
wdt:P9272 "55896"
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data from SPARQL profile: Wikidata