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rdfs:label
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"FYN"@cy
"FYN"@fa
"FYN"@it
"FYN"@uk
"FYN proto-oncogene, Src family tyrosine kinase"@en
"FYN proto-oncogene, Src family tyrosine kinase"@nl
"Fyn"@ru
"Tyrosinkinase Fyn"@de
"癌原遺伝子産物c-Fyn"@ja
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skos:altLabel
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"FYN"@en
"FYN oncogene related to SRC, FGR, YES"@en
"Fyn"@de
"OKT3-induced calcium influx regulator"@en
"SLK"@en
"c-syn protooncogene"@en
"p59-Fyn"@en
"proto-oncogene Syn"@en
"proto-oncogene c-Fyn"@en
"src-like kinase"@en
"src/yes-related novel"@en
"tyrosine kinase p59fyn(T)"@en
"tyrosine-protein kinase Fyn"@en
"がん原遺伝子チロシンプロテインキナーゼFyn"@ja
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schema:description
|
"Protein"@de
"enzima umano"@it
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in FYN proto-oncogene, Src family tyrosine kinase"@nl
"protèin"@ace
"protéine"@fr
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
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schema:dateModified
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"2026-07-23T06:53:03+00:00"^^xsd:dateTime
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schema:version
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2521520065
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wikibase:identifiers
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65
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wikibase:sitelinks
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7
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wd:statement/Q423628-84D9A9EE-53D6-480A-9A8F-E51F912656DA
|
|
wd:statement/Q423628-86B04E03-66AE-47CD-AF85-40B0682E80DE
|
|
wd:statement/Q423628-8872CB59-AA54-4928-8AD0-F8D373F84E36
|
|
wd:statement/Q423628-8F45482E-1522-4A61-9FD5-719F39DBF0E3
|
|
wd:statement/Q423628-95764E63-7E8B-4B6B-86E7-34070EEE053C
|
|
wd:statement/Q423628-9A7F288D-49D9-4F4E-BB0C-81A4248FC092
|
|
wd:statement/Q423628-9D3FFE08-D548-4D12-A2EC-1AF064BC67D2
|
|
wd:statement/Q423628-9F49C7EE-5539-4CEE-B655-183FA14B2560
|
|
wd:statement/Q423628-A0DF7F5E-FEF5-4038-91CA-6B92C693344F
|
|
wd:statement/Q423628-A1C5C1E1-0770-46B4-9F83-CB16D49B93DC
|
|
wd:statement/Q423628-A60D47DC-5AFF-47C1-9243-9C93BC4D896E
|
|
wd:statement/Q423628-A71EE11F-DE10-4232-90E4-BF00814D5434
|
|
wd:statement/Q423628-A81799A8-E3D4-4312-957B-DAA90C717ABD
|
|
wd:statement/Q423628-AC79A9FF-69D9-485A-B97D-E2B3FD2A1138
|
|
wd:statement/Q423628-B0DE8EE6-9455-420E-A961-204BC9738035
|
|
wd:statement/Q423628-B1B63607-AC39-4A46-9622-D55D8FB6F3DC
|
|
wd:statement/Q423628-BC496307-B9DD-48C6-A2FB-4AC1C8315404
|
|
wd:statement/Q423628-BCBFBDD7-5E17-4BF8-966D-0B0B06FE9EA3
|
|
wd:statement/Q423628-BF528DC9-FC63-4BF2-8D1B-DCC55F8D8441
|
|
wd:statement/Q423628-C978BE76-4FD9-4460-8A31-835FD56863C1
|
|
wd:statement/Q423628-C97E0FAE-FAA0-4E17-AD9B-78EEB6B341EA
|
|
wd:statement/Q423628-CA4B7984-EDF7-4A3C-B99C-734F1D97E49D
|
|
wd:statement/Q423628-CFA1D499-1143-462F-A029-18FEE900ADE3
|
|
wd:statement/Q423628-D1684021-927D-4C9A-9F3F-B8420EA88EBB
|
|
wd:statement/Q423628-D4DD323F-1739-4C2A-9756-17D33C4563E4
|
|
wd:statement/Q423628-D541EAD7-871D-4D5B-B70B-10869502D580
|
|
wd:statement/Q423628-D6B223D4-46B6-4C66-9708-B6734C1584EF
|
|
wd:statement/Q423628-D7BF3DFD-0728-4408-844F-3E42222A9383
|
|
wd:statement/Q423628-DC08189B-9058-4202-87D8-625E60A04101
|
|
wd:statement/Q423628-DFBD37B3-5104-4C14-933F-6864B0AC3EED
|
|
wd:statement/Q423628-E09C1875-BA6A-4197-9061-0C7F8EA59640
|
|
wd:statement/Q423628-E274D5A3-380A-4119-911C-68F0DA211EC0
|
|
wd:statement/Q423628-E933326F-932C-4DF9-A9AF-8293D65146F4
|
|
wd:statement/Q423628-E9D3343D-2BF3-49AD-9361-1C6A90317E72
|
|
wd:statement/Q423628-ECFF7AC7-BDFA-4D74-B0ED-9F7315A42ED6
|
|
wd:statement/Q423628-F260D456-A5B5-40D1-93D7-C59D30BEBA24
|
|
wd:statement/Q423628-F2A27590-A31B-4BED-B4C2-F628166E7193
|
|
wd:statement/Q423628-F319925A-64D9-413D-AEFA-312D52D9E9DA
|
|
wd:statement/Q423628-F366916F-31A7-4B1F-8928-6B180A7C2C1D
|
|
wd:statement/Q423628-FBF22503-93AB-4FC5-BC1A-FF1B52DDF933
|
|
wd:statement/Q423628-FE51DAF2-7D46-47BD-B507-FE803E97D9D0
|
|
p:P692
|
wd:statement/Q423628-AEAB3929-5ED3-4796-A538-97C5734EA029
|
|
p:P702
|
wd:statement/Q423628-8EC356B9-73A5-448B-9B14-D8601C23E998
|
|
p:P703
|
wd:statement/Q423628-2F3FEB0C-16AF-4845-9E34-63B24D1401AD
|
|
p:P705
|
wd:statement/Q423628-12AB41DE-C75A-4279-B961-56473DD4C132
|
|
wd:statement/Q423628-27C6EBD2-CAED-4241-829A-838FABF84B64
|
|
wd:statement/Q423628-2B8C3403-B2B6-425B-AE83-39C291445FDC
|
|
wd:statement/Q423628-30A5ECE2-AF82-4AD5-A968-DDD4220ABDAE
|
|
wd:statement/Q423628-316A8803-A44C-49B5-BA96-2EC73232823E
|
|
wd:statement/Q423628-33C49137-371A-4B7A-BA29-B24F4245A1AA
|
|
wd:statement/Q423628-35943742-D31F-4244-A573-E6B8BDEFF603
|
|
wd:statement/Q423628-52E5203B-CE0C-4C21-AD52-16EF78AA7863
|
|
wd:statement/Q423628-73875D8D-D0A6-4FC6-AF0B-2588BFFE1D39
|
|
wd:statement/Q423628-A14C877B-0972-4702-9F7A-F576C0007FC6
|
|
wd:statement/Q423628-A693AB03-DAFF-4847-B856-11898B12AEF8
|
|
wd:statement/Q423628-AE60BAC2-590E-43AC-AEAC-8C4534612372
|
|
wd:statement/Q423628-B8FCBB94-8D57-4F3B-8BAF-2C3744DEDC0B
|
|
wd:statement/Q423628-D450F145-90AE-495A-B009-9103787C5FA4
|
|
wd:statement/Q423628-DE37DC4A-DD66-4A54-8CB4-8660CC46EBFC
|
|
wd:statement/Q423628-E3051653-BE3A-4478-8B58-3D1513F4C75D
|
|
wd:statement/Q423628-EFADAF3B-3014-422E-9B74-9F6D56B5DB94
|
|
wd:statement/Q423628-F2588EF0-619C-41E3-B0AD-CD4BE730350D
|
|
wd:statement/Q423628-F85B9E73-F653-4415-A8DE-D1EDDC16D168
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P06241>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/D051076>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/2910472280>
|
|
<https://makg.org/entity/37686147>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001357458>
|
|
<http://purl.uniprot.org/refseq/NP_002028>
|
|
<http://purl.uniprot.org/refseq/NP_694592>
|
|
<http://purl.uniprot.org/refseq/NP_694593>
|
|
<http://purl.uniprot.org/refseq/XP_005266949>
|
|
<http://purl.uniprot.org/refseq/XP_016866139>
|
|
<http://purl.uniprot.org/refseq/XP_016866140>
|
|
<http://purl.uniprot.org/refseq/XP_016866141>
|
|
<http://purl.uniprot.org/refseq/XP_016866142>
|
|
<http://purl.uniprot.org/refseq/XP_016866144>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1A0N>
|
|
<https://rdf.wwpdb.org/pdb/1AOT>
|
|
<https://rdf.wwpdb.org/pdb/1AOU>
|
|
<https://rdf.wwpdb.org/pdb/1AVZ>
|
|
<https://rdf.wwpdb.org/pdb/1AZG>
|
|
<https://rdf.wwpdb.org/pdb/1EFN>
|
|
<https://rdf.wwpdb.org/pdb/1FYN>
|
|
<https://rdf.wwpdb.org/pdb/1G83>
|
|
<https://rdf.wwpdb.org/pdb/1M27>
|
|
<https://rdf.wwpdb.org/pdb/1NYF>
|
|
<https://rdf.wwpdb.org/pdb/1NYG>
|
|
<https://rdf.wwpdb.org/pdb/1SHF>
|
|
<https://rdf.wwpdb.org/pdb/1ZBJ>
|
|
<https://rdf.wwpdb.org/pdb/2DQ7>
|
|
<https://rdf.wwpdb.org/pdb/2MQI>
|
|
<https://rdf.wwpdb.org/pdb/2MRJ>
|
|
<https://rdf.wwpdb.org/pdb/2MRK>
|
|
<https://rdf.wwpdb.org/pdb/3H0F>
|
|
<https://rdf.wwpdb.org/pdb/3H0H>
|
|
<https://rdf.wwpdb.org/pdb/3H0I>
|
|
<https://rdf.wwpdb.org/pdb/3UA6>
|
|
<https://rdf.wwpdb.org/pdb/3UA7>
|
|
<https://rdf.wwpdb.org/pdb/4D8D>
|
|
<https://rdf.wwpdb.org/pdb/4EIK>
|
|
<https://rdf.wwpdb.org/pdb/4U17>
|
|
<https://rdf.wwpdb.org/pdb/4U1P>
|
|
<https://rdf.wwpdb.org/pdb/4ZNX>
|
|
p:direct-normalized/P672
|
<http://id.nlm.nih.gov/mesh/D08.811.913.696.620.682.725.800.551>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.476.568.800.551>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.624.664.700.180>
|
|
wdt:P10283
|
"C37686147"
|
|
wdt:P129
|
bosutinib
|
|
wdt:P18
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20Protein%20FYN%20image.jpg>
|
|
wdt:P2888
|
<http://purl.uniprot.org/uniprot/P06241>
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P06241"
|
|
wdt:P361
|
Protein kinase-like domain superfamily
|
|
SH3-like domain superfamily
|
|
SH2 domain superfamily
|
|
Src family kinases (SFKs) [cytosol]
|
|
Tyrosine-protein kinase, catalytic domain, protein family
|
|
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
|
|
Protein kinase domain, protein family
|
|
SH3 domain, protein family
|
|
SH2 domain, protein family
|
|
Fyn/Yrk, SH3 domain, protein family
|
|
Tyrosine-protein kinase, active site, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P486
|
"D051076"
|
|
wdt:P527
|
tyrosine-protein kinase, catalytic domain
|
|
tyrosine-protein kinase, active site
|
|
serine-threonine/tyrosine-protein kinase, catalytic domain
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
SH3 domain
|
|
SH2 domain
|
|
Fyn/Yrk, SH3 domain
|
|
wdt:P591
|
"2.7.10.2"
|
|
wdt:P6366
|
"2910472280"
|
|
"37686147"
|
|
wdt:P637
|
"NP_001357458"
|
|
"NP_002028"
|
|
"NP_694592"
|
|
"NP_694593"
|
|
"XP_005266949"
|
|
"XP_016866139"
|
|
"XP_016866140"
|
|
"XP_016866141"
|
|
"XP_016866142"
|
|
"XP_016866144"
|
|
wdt:P638
|
"1A0N"
|
|
"1AOT"
|
|
"1AOU"
|
|
"1AVZ"
|
|
"1AZG"
|
|
"1EFN"
|
|
"1FYN"
|
|
"1G83"
|
|
"1M27"
|
|
"1NYF"
|
|
"1NYG"
|
|
"1SHF"
|
|
"1ZBJ"
|
|
"2DQ7"
|
|
"2MQI"
|
|
"2MRJ"
|
|
"2MRK"
|
|
"3H0F"
|
|
"3H0H"
|
|
"3H0I"
|
|
"3UA6"
|
|
"3UA7"
|
|
"4D8D"
|
|
"4EIK"
|
|
"4U17"
|
|
"4U1P"
|
|
"4ZNX"
|
|
wdt:P646
|
"/m/03cc30q"
|
|
wdt:P672
|
"D08.811.913.696.620.682.725.800.551"
|
|
"D12.776.476.568.800.551"
|
|
"D12.776.624.664.700.180"
|
|
wdt:P680
|
metal ion binding
|
|
enzyme binding
|
|
tubulin binding
|
|
identical protein binding
|
|
ATP binding
|
|
signaling receptor binding
|
|
G protein-coupled receptor binding
|
|
peptide hormone receptor binding
|
|
protein kinase activity
|
|
signal transducer activity
|
|
transferase activity
|
|
nucleotide binding
|
|
alpha-tubulin binding
|
|
tau protein binding
|
|
kinase activity
|
|
protein tyrosine kinase activity
|
|
phosphatidylinositol 3-kinase binding
|
|
growth factor receptor binding
|
|
non-membrane spanning protein tyrosine kinase activity
|
|
CD4 receptor binding
|
|
CD8 receptor binding
|
|
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
|
ephrin receptor binding
|
|
transmembrane transporter binding
|
|
T cell receptor binding
|
|
tau-protein kinase activity
|
|
protein binding
|
|
type 5 metabotropic glutamate receptor binding
|
|
protein-containing complex binding
|
|
disordered domain specific binding
|
|
wdt:P681
|
dendrite
|
|
perinuclear region of cytoplasm
|
|
membrane
|
|
intracellular membrane-bounded organelle
|
|
cell periphery
|
|
cell body
|
|
extrinsic component of cytoplasmic side of plasma membrane
|
|
perinuclear endoplasmic reticulum
|
|
glial cell projection
|
|
cytosol
|
|
glutamatergic synapse
|
|
postsynaptic density, intracellular component
|
|
plasma membrane
|
|
Schaffer collateral - CA1 synapse
|
|
actin filament
|
|
mitochondrion
|
|
nucleus
|
|
membrane raft
|
|
postsynaptic density
|
|
cytoplasm
|
|
endosome
|
|
wdt:P682
|
learning
|
|
forebrain development
|
|
neuron migration
|
|
central nervous system development
|
|
positive regulation of neuron projection development
|
|
positive regulation of phosphatidylinositol 3-kinase signaling
|
|
peptidyl-tyrosine phosphorylation
|
|
modulation of chemical synaptic transmission
|
|
calcium ion transport
|
|
regulation of apoptotic process
|
|
multicellular organism development
|
|
MAPK cascade
|
|
negative regulation of protein catabolic process
|
|
positive regulation of protein kinase B signaling
|
|
regulation of cell population proliferation
|
|
response to hydrogen peroxide
|
|
regulation of cell shape
|
|
platelet activation
|
|
leukocyte migration
|
|
cellular response to growth factor stimulus
|
|
feeding behavior
|
|
negative regulation of gene expression
|
|
response to ethanol
|
|
cell surface receptor signaling pathway
|
|
negative regulation of neuron apoptotic process
|
|
intracellular signal transduction
|
|
cytokine-mediated signaling pathway
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
|
phosphatidylinositol-mediated signaling
|
|
Fc-gamma receptor signaling pathway involved in phagocytosis
|
|
T cell activation
|
|
T cell receptor signaling pathway
|
|
positive regulation of I-kappaB kinase/NF-kappaB signaling
|
|
dendrite morphogenesis
|
|
regulation of peptidyl-tyrosine phosphorylation
|
|
viral process
|
|
T cell costimulation
|
|
mitigation of host defenses by virus
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
|
positive regulation of protein localization to nucleus
|
|
cellular response to transforming growth factor beta stimulus
|
|
positive regulation of cysteine-type endopeptidase activity
|
|
vascular endothelial growth factor receptor signaling pathway
|
|
phosphatidylinositol phosphate biosynthetic process
|
|
adaptive immune response
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
|
negative regulation of protein ubiquitination
|
|
activated T cell proliferation
|
|
ephrin receptor signaling pathway
|
|
cellular response to peptide hormone stimulus
|
|
positive regulation of GTPase activity
|
|
positive regulation of tyrosine phosphorylation of STAT protein
|
|
positive regulation of neuron death
|
|
immune system process
|
|
peptidyl-tyrosine autophosphorylation
|
|
blood coagulation
|
|
cell migration
|
|
axon guidance
|
|
cell differentiation
|
|
dendritic spine maintenance
|
|
stimulatory C-type lectin receptor signaling pathway
|
|
cellular response to platelet-derived growth factor stimulus
|
|
negative regulation of oxidative stress-induced cell death
|
|
positive regulation of non-membrane spanning protein tyrosine kinase activity
|
|
positive regulation of protein targeting to membrane
|
|
regulation of phosphatidylinositol 3-kinase signaling
|
|
negative regulation of hydrogen peroxide biosynthetic process
|
|
negative regulation of dendritic spine maintenance
|
|
response to singlet oxygen
|
|
response to amyloid-beta
|
|
cellular response to amyloid-beta
|
|
regulation of glutamate receptor signaling pathway
|
|
heart process
|
|
phosphorylation
|
|
cellular response to L-glutamate
|
|
cellular response to glycine
|
|
positive regulation of protein localization to membrane
|
|
regulation of calcium ion import across plasma membrane
|
|
protein autophosphorylation
|
|
innate immune response
|
|
protein phosphorylation
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20FYN%20210105%20s%20at%20fs.png>
|
|
wdt:P702
|
FYN
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000229471"
|
|
"ENSP00000346671"
|
|
"ENSP00000357656"
|
|
"ENSP00000357667"
|
|
"ENSP00000357671"
|
|
"ENSP00000427993"
|
|
"ENSP00000428042"
|
|
"ENSP00000428045"
|
|
"ENSP00000428493"
|
|
"ENSP00000428695"
|
|
"ENSP00000428983"
|
|
"ENSP00000429294"
|
|
"ENSP00000429590"
|
|
"ENSP00000429813"
|
|
"ENSP00000429866"
|
|
"ENSP00000429992"
|
|
"ENSP00000430364"
|
|
"ENSP00000430455"
|
|
"ENSP00000440646"
|
