SHMARQL

eplerenone

<http://www.wikidata.org/entity/Q423804>

steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure
rdfs:label
"eplerenone"@en
skos:altLabel
"107724-20-9"@fr
"Eplerenone"@fr
schema:description
"steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure"@en
schema:dateModified "2026-11-04T14:16:03+00:00"^^xsd:dateTime
schema:version 2564717306
wikibase:identifiers 36
wikibase:sitelinks 22
wikibase:statements 141
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p:P7830 wd:statement/Q423804-71B075BC-213B-49B2-8DD1-068315298D37
p:P8026 wd:statement/Q423804-F8D58C7D-3267-43EF-B1F5-57F990A60504
p:P8494 wd:statement/Q423804-4E13DEC5-B423-4AB5-A38D-847026642F76
p:direct-normalized/P2115 <http://purl.bioontology.org/ontology/NDFRT/N0000148782>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D000077545>
p:direct-normalized/P592 <http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL1095097>
p:direct-normalized/P6366 <https://makg.org/entity/2780072264>
p:direct-normalized/P661 <http://rdf.chemspider.com/132492>
p:direct-normalized/P662 <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID443872>
p:direct-normalized/P665 <http://www.kegg.jp/entry/D01115>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D02.540.383>
<http://id.nlm.nih.gov/mesh/D04.210.500.745.745.329>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_31547>
wdt:P10245 "a603004"
wdt:P10283 "C2780072264"
wdt:P11089 "543755"
wdt:P11143 "Eplerenone"
wdt:P11198 "1032"
wdt:P11199 "PD009838"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Eplerenon.svg>
wdt:P1748 "C47513"
wdt:P2017 "COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@@]34O[C@@H]3C[C@@]5(C)[C@@H](CC[C@@]56CCC(=O)O6)[C@H]14"
"C[C@]12CCC(=O)C=C1C[C@H]([C@@H]3[C@]24[C@H](O4)C[C@]5([C@H]3CC[C@@]56CCC(=O)O6)C)C(=O)OC"
wdt:P2057 "HMDB0014838"
wdt:P2062 "7522"
wdt:P2067 414.204239^^xsd:decimal
wdt:P2115 "N0000148782"
wdt:P2175 arterial hypertension
wdt:P231 "107724-20-9"
wdt:P232 "600-850-8"
wdt:P233 "CC12CCC(=O)C=C1CC(C3C24C(O4)CC5(C3CCC56CCC(=O)O6)C)C(=O)OC"
wdt:P234 "InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1"
wdt:P235 "JUKPWJGBANNWMW-VWBFHTRKSA-N"
wdt:P2566 "100.106.615"
wdt:P267 "C03DA04"
wdt:P274 "C₂₄H₃₀O₆"
wdt:P279 LSM-1524
wdt:P2868 antimineralocorticoid
wdt:P2877 "21515"
wdt:P2892 "C0961485"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID2046094"
wdt:P3345 "298869"
wdt:P3489 US pregnancy category B
Australian pregnancy category B3
wdt:P3493 boxed warning
wdt:P3636 "YNU"
wdt:P366 medication
wdt:P373 "Eplerenone"
wdt:P3780 Inspra
wdt:P4235 "eplerenone"
wdt:P4250 50.0^^xsd:decimal
wdt:P486 "D000077545"
wdt:P592 "CHEMBL1095097"
wdt:P595 "2876"
wdt:P6366 "2780072264"
wdt:P646 "/m/0bd3st"
wdt:P652 "6995V82D0B"
wdt:P661 "132492"
wdt:P662 "443872"
wdt:P665 "D01115"
wdt:P672 "D02.540.383"
"D04.210.500.745.745.329"
wdt:P683 "31547"
wdt:P715 "DB00700"
wdt:P769 naproxen
valsartan
ibuprofen
triamterene
Diclofenac
(RS)-etodolac
(RS)-fenoprofen
perindopril
parecoxib
piroxicam
celecoxib
(RS)-ketoprofen
indomethacin
losartan
itraconazole
ramipril
meloxicam
candesartan
(±)-flurbiprofen
amiloride
captopril
enalapril
spironolactone
trimethoprim
nabumetone
fosinopril
tenoxicam
lisinopril dihydrate
aceclofenac
quinapril
telmisartan
trandolapril
irbesartan
sulindac
wdt:P7830 "Eplerenone"
wdt:P8026 LiverTox toxicity likelihood category E*
wdt:P8494 "DTXCID0026094"
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