SHMARQL

cytochrome P450 family 3 subfamily A member 4

<http://www.wikidata.org/entity/Q424440>

mammalian protein found in Homo sapiens
rdfs:label
"cytochrome P450 family 3 subfamily A member 4"@en
skos:altLabel
"1,8-cineole 2-exo-monooxygenase"@en
"1.14.13.157"@en
"1.14.13.32"@en
"1.14.13.67"@en
"1.14.13.97"@en
"1.14.14.1"@en
"CYP3A4"@en
"CYPIIIA3"@en
"CYPIIIA4"@en
"P450-III, steroid inducible"@en
"albendazole monooxygenase"@en
"albendazole monooxygenase (sulfoxide-forming)"@en
"albendazole sulfoxidase"@en
"cholesterol 25-hydroxylase"@en
"cytochrome P450 3A3"@en
"cytochrome P450 3A4"@en
"cytochrome P450 HLp"@en
"cytochrome P450 NF-25"@en
"cytochrome P450, family 3, subfamily A, polypeptide 4"@en
"cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3"@en
"cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4"@en
"cytochrome P450-PCN1"@en
"glucocorticoid-inducible P450"@en
"nifedipine oxidase"@en
"quinine 3-monooxygenase"@en
"taurochenodeoxycholate 6-alpha-hydroxylase"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-07-23T06:53:20+00:00"^^xsd:dateTime
schema:version 2521520133
wikibase:identifiers 34
wikibase:sitelinks 22
wikibase:statements 87
p:P10283 wd:statement/Q424440-4A233085-BF6A-4347-A786-715F6312260B
p:P129 wd:statement/Q424440-812D7074-C5EC-4A2E-A596-EEB66CD32D69
wd:statement/Q424440-8EA5EE6E-B4BF-4654-9F05-DA34E66B17B7
wd:statement/Q424440-F9C46023-91AD-4932-9EC8-DA4CF2BA8C47
p:P2888 wd:statement/Q424440-1879588A-F2B6-4BB6-A6F7-5C1C77DCBD3F
p:P31 wd:statement/Q424440-9F713B34-637A-4F79-8619-0466CE28D973
p:P352 wd:statement/q424440-5EA321FB-234D-4992-B23D-011EBB0DB08C
p:P361 wd:statement/Q424440-6A6762D5-F98A-41AD-AC28-3E745109E38F
wd:statement/Q424440-85F20607-0548-4319-8813-4B67B31E2E52
wd:statement/Q424440-966EA3E2-3905-4D16-9404-AB63D9EE1B29
p:P527 wd:statement/Q424440-6DF0E810-F6E3-45AF-99B1-B07D48CF9E0C
p:P591 wd:statement/Q424440-23BC1A3E-8ABF-4A99-BD8A-618C30D79807
wd:statement/Q424440-84FE28D0-0173-4AFC-9775-47442EA6CFA7
wd:statement/Q424440-869A79E2-AEDC-47CD-AA57-1597E4809FA0
wd:statement/Q424440-89B3D2F3-EA04-4B2C-A09F-3D0DDBA21C43
wd:statement/Q424440-CEF6A30E-A00D-4F4B-8241-0040B703B61D
p:P6366 wd:statement/Q424440-1C8BA097-44C7-4CE7-81A2-DD7995845CB0
wd:statement/Q424440-73F5968F-DE36-4BC3-924C-64AAF5B9F5C6
p:P637 wd:statement/Q424440-0C220F5C-2F60-4707-BCD7-31F22CDC6918
wd:statement/Q424440-4CE6A497-2654-4E30-A835-870D6DEF047D
p:P638 wd:statement/Q424440-1DC2155E-05BF-4FA0-9250-553CB62F65CD
wd:statement/Q424440-231FEBB5-F99F-4B98-82A8-1D143E2BBFA2
wd:statement/Q424440-8F1A1CA7-1D70-4770-86B5-1911EC117C95
wd:statement/Q424440-B2BA86C3-9E8A-4159-BA3E-7213ECDCC643
wd:statement/Q424440-B5884874-A076-4E7E-B070-22A68FE18C33
wd:statement/Q424440-B5D6EF62-7AB5-4E14-85FD-70A9EAB84681
wd:statement/Q424440-DEA9E167-644D-4091-A36B-49144535C7AE
wd:statement/q424440-00A38F7C-404B-4F35-83BF-56CE06695E7C
wd:statement/q424440-0673CBAF-72F4-481A-B7CA-F9DB4794351B
wd:statement/q424440-1749BFC4-E2E4-481D-92EC-346AD68D22D0
wd:statement/q424440-18D9974F-86D9-4069-A5DA-3C8876F92AF3
wd:statement/q424440-26A0B696-8DE4-41EC-950D-727D400FA2BA
wd:statement/q424440-2A54952A-39D4-4E00-91F1-6EBA65A0204F
wd:statement/q424440-2EDDB83A-E53B-4C68-A21E-5F7DED116D0C
wd:statement/q424440-5B7DBE56-3C1C-46FF-BAC4-254BFB319386
wd:statement/q424440-5E2EF6C6-FF8B-45FF-BA6B-0BB6ABE4FA90
wd:statement/q424440-78065917-91C7-4C64-B3BB-89744D2B3C02
wd:statement/q424440-8B2C23C1-352E-4D7E-99AF-668F70B9FA8C
wd:statement/q424440-93BFE4EB-D2A1-4F49-961A-957EE6663509
wd:statement/q424440-A7BDFCBE-D90C-4C11-9D26-37019F05D602
wd:statement/q424440-AD229641-0494-4781-BFB4-3C6E425A4BFE
wd:statement/q424440-C2C51A7B-A3B4-4CEE-B846-F516F02AB6C4
wd:statement/q424440-D406344B-AB2C-48A7-AD60-CA55EBAB73A8
wd:statement/q424440-F813BFA7-F00D-446D-A36B-69BAA8D89805
p:P646 wd:statement/Q424440-95E6467C-3AA6-484A-A4C7-E948ECD3ED33
p:P680 wd:statement/Q424440-0815809F-2692-4DF3-83EF-186CCECF2B4C
wd:statement/Q424440-11D40D94-7136-4262-949D-13EBB1DF1947
wd:statement/Q424440-170B6531-C879-46D6-B393-59CA28CCCA1B
wd:statement/Q424440-282D75EF-C02C-4DE3-A219-89B9A1630AA9
wd:statement/Q424440-29820F75-E4A3-4568-9C92-194D7F0F44D2
wd:statement/Q424440-394F7CD7-2D8F-4AE2-A819-A2D929271C51
wd:statement/Q424440-47B44798-CF74-4022-9982-68410F645FF6
wd:statement/Q424440-4FE13C78-3D51-460D-AE31-1EE248B4AE58
wd:statement/Q424440-82EFC4D6-3FA2-4922-9FD2-B68B314A3E77
wd:statement/Q424440-898A2486-2B1F-4BFE-8526-ABF322E0D153
wd:statement/Q424440-A29D1708-89FE-4BB0-A08B-99E605F57D33
wd:statement/Q424440-BEEA047F-F198-4D4A-95D3-978006DC0609
wd:statement/Q424440-CAD8BB0C-9B93-4AF9-90BA-9793F5847E88
wd:statement/Q424440-DBC15E7B-5EB4-4FE5-960C-D0D7324AC75D
wd:statement/Q424440-E0FE900F-81D1-4D88-AD8C-1596194E9C5A
wd:statement/Q424440-E893B344-8352-4541-9BA2-0EB7AD2CF1C3
p:P681 wd:statement/Q424440-0641EC43-B8D2-4C46-8817-4CFF5D00407F
wd:statement/Q424440-417C9A60-A30C-4BC8-B16A-087375B4A4DE
wd:statement/Q424440-47FECB7A-D494-4433-BB1E-E376DF54B978
wd:statement/Q424440-55C810A8-826B-424B-BBB7-9D2F56CD0870
wd:statement/Q424440-770E49E7-1979-43FC-8273-E8EBEFF87C5C
wd:statement/Q424440-E1A25A2D-AF10-4707-8DFF-7B751EB8D608
wd:statement/Q424440-ED936911-F1A6-4884-8066-83A5612B4749
p:P682 wd:statement/Q424440-16202016-7472-4CC8-BCF9-E498AB7ED415
wd:statement/Q424440-2038E5E7-6CFE-4624-8885-DE4EF0468486
wd:statement/Q424440-46DD2498-E06A-49F9-836A-A2A7D0AB2AB9
wd:statement/Q424440-49DF1D35-C87F-472A-BC78-8DC65CBF0735
wd:statement/Q424440-4FA85735-81D0-4A21-9FEF-6A27BCA45D62
wd:statement/Q424440-5CDC475A-CCBC-464F-84EA-69EE2EAB5A3A
wd:statement/Q424440-6F92550A-4614-4A2D-A361-D6BDA72C99E4
wd:statement/Q424440-94F9E7CF-20AD-455C-8643-1FFB616B7C12
wd:statement/Q424440-B05D2FDD-0EBE-4B16-AF20-AB3721B732B8
wd:statement/Q424440-CC3CAFDD-563A-4EC0-89A2-645D0515CA02
wd:statement/Q424440-CC52A883-2A3C-4134-B02E-277E47DF2F03
wd:statement/Q424440-DB551ED8-5922-459F-BC75-E2DECD383090
wd:statement/Q424440-FE94FED4-77D2-4606-910C-9F19EDA4CE47
p:P692 wd:statement/Q424440-F9724A63-C65C-4FDA-B976-5DB7A009997F
p:P702 wd:statement/q424440-6DA3CA3B-90BD-4419-85F0-36A504D1AC01
p:P703 wd:statement/Q424440-E1C133F3-9326-4E54-ACDD-C68CA3D099AE
p:P705 wd:statement/Q424440-74315BCE-D7E0-4E58-BE16-4F59A879E403
wd:statement/Q424440-B4560F21-1D14-4B64-8ABD-B408797B45D5
wd:statement/q424440-4D062A59-C4CC-4A75-94FC-5172B9DEDFB7
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P08684>
p:direct-normalized/P6366 <https://makg.org/entity/109650736>
<https://makg.org/entity/2910128900>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_001189784>
<http://purl.uniprot.org/refseq/NP_059488>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1TQN>
<https://rdf.wwpdb.org/pdb/1W0E>
<https://rdf.wwpdb.org/pdb/1W0F>
<https://rdf.wwpdb.org/pdb/1W0G>
<https://rdf.wwpdb.org/pdb/2J0D>
<https://rdf.wwpdb.org/pdb/2V0M>
<https://rdf.wwpdb.org/pdb/3NXU>
<https://rdf.wwpdb.org/pdb/3TJS>
<https://rdf.wwpdb.org/pdb/3UA1>
<https://rdf.wwpdb.org/pdb/4D6Z>
<https://rdf.wwpdb.org/pdb/4D75>
<https://rdf.wwpdb.org/pdb/4D78>
<https://rdf.wwpdb.org/pdb/4D7D>
<https://rdf.wwpdb.org/pdb/4I3Q>
<https://rdf.wwpdb.org/pdb/4I4G>
<https://rdf.wwpdb.org/pdb/4I4H>
<https://rdf.wwpdb.org/pdb/4K9T>
<https://rdf.wwpdb.org/pdb/4K9U>
<https://rdf.wwpdb.org/pdb/4K9V>
<https://rdf.wwpdb.org/pdb/4K9W>
<https://rdf.wwpdb.org/pdb/4K9X>
<https://rdf.wwpdb.org/pdb/4NY4>
<https://rdf.wwpdb.org/pdb/5A1P>
<https://rdf.wwpdb.org/pdb/5A1R>
wdt:P10283 "C109650736"
wdt:P129 verapamil
nefazodone
ritonavir
wdt:P2888 <http://purl.uniprot.org/uniprot/P08684>
wdt:P31 protein
wdt:P352 "P08684"
wdt:P361 cytochrome P450, E-class, CYP3A
cytochrome P450 superfamily
cytochrome P450, conserved site, protein family
wdt:P527 cytochrome P450, conserved site
wdt:P591 "1.14.13.32"
"1.14.14.1"
"1.14.14.55"
"1.14.14.56"
"1.14.14.73"
wdt:P6366 "109650736"
"2910128900"
wdt:P637 "NP_001189784"
"NP_059488"
wdt:P638 "1TQN"
"1W0E"
"1W0F"
"1W0G"
"2J0D"
"2V0M"
"3NXU"
"3TJS"
"3UA1"
"4D6Z"
"4D75"
"4D78"
"4D7D"
"4I3Q"
"4I4G"
"4I4H"
"4K9T"
"4K9U"
"4K9V"
"4K9W"
"4K9X"
"4NY4"
"5A1P"
"5A1R"
wdt:P646 "/m/03_8ml"
wdt:P680 metal ion binding
steroid binding
oxidoreductase activity
iron ion binding
steroid hydroxylase activity
heme binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
enzyme binding
oxygen binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
vitamin D3 25-hydroxylase activity
caffeine oxidase activity
testosterone 6-beta-hydroxylase activity
vitamin D 24-hydroxylase activity
estrogen 16-alpha-hydroxylase activity
wdt:P681 integral component of membrane
endoplasmic reticulum membrane
membrane
intracellular membrane-bounded organelle
organelle membrane
cytoplasm
endoplasmic reticulum
wdt:P682 steroid metabolic process
xenobiotic metabolic process
vitamin D metabolic process
androgen metabolic process
steroid catabolic process
alkaloid catabolic process
monoterpenoid metabolic process
heterocycle metabolic process
oxidative demethylation
calcitriol biosynthetic process from calciol
long-chain fatty acid biosynthetic process
lipid hydroxylation
lipid metabolism
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20TNFRSF11B%20204932%20at%20tn.png>
wdt:P702 CYP3A4
wdt:P703 man
wdt:P705 "ENSP00000337915"
"ENSP00000346607"
"ENSP00000397208"
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data from SPARQL profile: Wikidata