SHMARQL

Adrenoceptor alpha 2A

<http://www.wikidata.org/entity/Q4734892>

mammalian protein found in Homo sapiens
rdfs:label
"Adrenoceptor alpha 2A"@en
skos:altLabel
"ADRA2A"@en
"Alpha-2AAR"@en
"adrenergic, alpha-2A-, receptor"@en
"alpha-2 adrenergic receptor subtype C10"@en
"alpha-2-adrenergic receptor, platelet type"@en
"alpha-2A adrenergic receptor"@en
"alpha-2A adrenoceptor"@en
"alpha-2A adrenoreceptor"@en
"alpha-2AAR subtype C10"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-01-28T14:47:47+00:00"^^xsd:dateTime
schema:version 2458679033
wikibase:identifiers 7
wikibase:sitelinks 0
wikibase:statements 115
p:P129 wd:statement/Q4734892-017C7BAF-97C0-46F4-B103-2E10C3791E5F
wd:statement/Q4734892-0352D803-7061-4B9D-BC98-3AEF4BD7BFAE
wd:statement/Q4734892-0BC440E6-26F7-4FFC-AE45-6C5A204277E1
wd:statement/Q4734892-17A2D50E-8E24-4325-9DB9-7FE0D43E03F5
wd:statement/Q4734892-19236045-EC7C-45C2-9D36-3F406B94D75B
wd:statement/Q4734892-3E401163-745F-4F60-927C-3D69347023D2
wd:statement/Q4734892-442A3CFD-141F-4C64-B82A-E546C48F50A9
wd:statement/Q4734892-6B3CF067-DACE-4B1F-920B-ACDE27D28D94
wd:statement/Q4734892-6E34FA6F-A676-46E5-B0A7-8497DB5B769C
wd:statement/Q4734892-6F660BEC-E2E5-42D1-86B7-E6115C3F3505
wd:statement/Q4734892-76AADE2E-BEF3-4F6C-B7BC-B734E592C1E1
wd:statement/Q4734892-7E197F09-E2F0-4C6A-ABDB-E9524E68D561
wd:statement/Q4734892-7F0D6DAF-6F05-4BBA-9AA1-0C67EE9B94B7
wd:statement/Q4734892-83A28B52-6F74-4F15-BF76-813784B1C8DC
wd:statement/Q4734892-86609E41-5B0D-4515-8D29-891E1934F0DD
wd:statement/Q4734892-87B27E12-E33E-445D-84B3-8C6FA40FD148
wd:statement/Q4734892-8ED08BB6-709E-4D6F-8ABB-3DC5D3C81FBB
wd:statement/Q4734892-91250CEE-D836-4972-B785-525130EB0F20
wd:statement/Q4734892-9562F3CC-0D57-41FE-A8E9-D86925465737
wd:statement/Q4734892-A70A6D99-D084-487A-ACE7-D921C351BFC6
wd:statement/Q4734892-ACC166B9-8152-469C-AAF7-C3AD69577E06
wd:statement/Q4734892-B198909A-A3D0-465E-AB8D-233B49AF782E
wd:statement/Q4734892-B35C5D8F-D251-4637-868D-E371B4FB5736
wd:statement/Q4734892-B5292198-8FCC-4E50-91A3-456621508CD7
wd:statement/Q4734892-BBB3661D-5FB5-422D-93DD-BC314C68DCBC
wd:statement/Q4734892-BDD7BCD2-3E03-4280-8D32-87535C277ECB
wd:statement/Q4734892-C02F77EB-FF15-4BCF-94BE-EF7BF7A6E69A
wd:statement/Q4734892-C2E80262-25CB-426E-91DC-A30F119A93CF
wd:statement/Q4734892-C5011139-ED4A-4D8B-8A68-38869FD139AD
wd:statement/Q4734892-CE573003-0CA7-4054-B3C5-1192EEADC5A3
wd:statement/Q4734892-CFAE9C06-80A3-423E-8B2E-1752EA0D4FD0
wd:statement/Q4734892-D1B5CF43-AADA-4153-BD77-516D0BB872C4
wd:statement/Q4734892-D27DA3E8-31CD-4EF4-A3B3-47810BB965F0
wd:statement/Q4734892-E1B2A66F-B0E4-4ECB-8CAD-A80531C741E6
wd:statement/Q4734892-E97C39A6-A3F9-4796-86A1-575CCCE86D5F
wd:statement/Q4734892-F4B0143D-8094-42E8-880D-8985D1BD0B99
wd:statement/Q4734892-FF5224AC-4831-4C5D-9567-D9077D930474
p:P31 wd:statement/Q4734892-C71845DA-7CC4-4740-A705-00A76DEA5BFD
p:P352 wd:statement/Q4734892-766DAB17-6B8B-4F05-BB55-6108D161FB62
p:P361 wd:statement/Q4734892-12DA3F4B-FF12-41EB-9530-197091711AC5
wd:statement/Q4734892-BFE111FF-443B-4353-B7BB-ECBCC0D5E15B
p:P527 wd:statement/Q4734892-CFE09078-6B38-4699-9F93-01C6A3F52EF6
p:P637 wd:statement/Q4734892-9CAF9B8A-CC08-4A79-B9C6-6F4A064746A0
p:P638 wd:statement/Q4734892-3F4A4E84-8D28-498A-B2F0-A29A7419FA87
wd:statement/Q4734892-5A7E6535-0BA8-4420-9F33-2F4FAD1805C6
wd:statement/Q4734892-5C9A2D2A-12A8-4DEC-BB86-F3610B57D846
wd:statement/Q4734892-A825C93F-F125-48F0-884E-714427B66563
p:P680 wd:statement/Q4734892-042CB9B4-975D-4FA8-8771-893B2C3BF1E7
wd:statement/Q4734892-094A2EA1-FF9D-4910-9DBA-C01928F104D9
wd:statement/Q4734892-3C182A00-85DF-4B63-A918-53ED10CFCD05
wd:statement/Q4734892-3DEE7304-5BA3-456F-99A8-C7EFC8E84AC5
wd:statement/Q4734892-3E7D548E-60BE-4D33-AE37-C5006500FF6C
wd:statement/Q4734892-69B35FAD-0842-4D5C-A1DD-4FD092207479
wd:statement/Q4734892-80B32B20-9F19-4068-9787-18973DE23C11
wd:statement/Q4734892-83BF10AC-DB8E-4B43-AAD6-84C7AE86A984
wd:statement/Q4734892-B280BF45-CAEC-49B0-B8C0-A59A75C484F0
wd:statement/Q4734892-B583FF8C-D6C7-4A32-9810-A0011FAA3A9E
wd:statement/Q4734892-C0CE8451-0D75-4432-A131-ED292482F274
wd:statement/Q4734892-C1E5E9F4-3AC0-480A-9FFB-18A64327EBF7
wd:statement/Q4734892-C7B015EE-BB59-4EBD-B64A-AE5E95D1B6EC
wd:statement/Q4734892-D4D5C1C8-EB50-4145-BADC-BF8C40B76D38
wd:statement/Q4734892-EA7579FD-7403-4786-871D-516C0608B877
p:P681 wd:statement/Q4734892-06321F51-0FEC-45E3-86E2-B9D19AD4F060
wd:statement/Q4734892-070470BB-CC7E-4114-A07B-85BA2BBDE504
wd:statement/Q4734892-1E00080D-A62D-4AB4-82EB-A883694F76CE
wd:statement/Q4734892-59CA4A7E-CDDF-42A1-81E5-0542323A6D83
wd:statement/Q4734892-669AC46A-5823-4786-8249-936BAEF8AA02
wd:statement/Q4734892-6CD05B7E-D693-4B34-9133-0C68F2BF32CB
wd:statement/Q4734892-95FED4C8-DBD0-475C-B508-7C92B9952D93
wd:statement/Q4734892-D81E7528-C7E1-45FB-B075-1776AFD41B1A
p:P682 wd:statement/Q4734892-01248501-FCC7-4ED9-9461-A9C81A391651
wd:statement/Q4734892-05376DB0-C9D4-457F-87C3-ADC6D3C3D3A3
wd:statement/Q4734892-08DAE74E-E947-4F8B-A335-B7449A66E810
wd:statement/Q4734892-0BCA2BCB-579F-4602-AF38-AAD53815BDE9
wd:statement/Q4734892-0EB1A3F6-37FE-4E93-BF9D-117BCBAE91FD
wd:statement/Q4734892-124BE381-B0F7-4926-B8F8-7041215CA30D
wd:statement/Q4734892-180792EA-E5B5-4D97-9969-64BA3CD93E52
wd:statement/Q4734892-195A5E93-7878-49D5-88AC-40D695CC3ECE
wd:statement/Q4734892-1B26C241-3D2C-40CE-91A6-04F8F459EC60
wd:statement/Q4734892-1CFC9D5D-679E-40B1-91F5-927EFACAF218
wd:statement/Q4734892-2BC2C178-3CDF-4EE3-87BB-48E0D9A1F16F
wd:statement/Q4734892-303A0953-3F1C-423B-8A19-A613BE21A224
wd:statement/Q4734892-34E69477-970F-4EE5-8C23-4E680BD1D6B2
wd:statement/Q4734892-4201E270-5AF5-4D6F-A687-27F6E55CF66B
wd:statement/Q4734892-4614A3D2-95D7-485B-8EAF-6E24870D49CF
wd:statement/Q4734892-4ED0E710-1478-43B5-ABF9-28E609129A19
wd:statement/Q4734892-5198D89B-3BC9-4AA7-A2C3-91C924E15152
wd:statement/Q4734892-54709656-BC5B-49CD-88FE-75A81A874875
wd:statement/Q4734892-6B295B35-1050-470F-8177-58012D2C536E
wd:statement/Q4734892-6C8B465B-3CD6-44FE-A655-C2C474051954
wd:statement/Q4734892-6D2C3537-E598-4E3B-9B4F-2C15F5521ACD
wd:statement/Q4734892-6D46F554-08DF-45CF-94CB-FD074E65102E
wd:statement/Q4734892-6DFBDDD7-FA5D-4DFC-AD00-351947EA7B2B
wd:statement/Q4734892-736874F6-5D49-40C1-9541-346579408569
wd:statement/Q4734892-739BACBE-FA30-4ABE-8345-7B6674EA13A6
wd:statement/Q4734892-744402A8-A1E9-4192-95E8-3E61AE2EA61C
wd:statement/Q4734892-771B4E61-62B2-435A-AF30-D83709EFFAD4
wd:statement/Q4734892-80383C57-C89B-46C8-9C8F-B4421FA7FE82
wd:statement/Q4734892-9BD10984-56A3-4CD2-A8A8-0269F51DB1D9
wd:statement/Q4734892-A763A2DF-E801-4880-B073-6027A7A11F57
wd:statement/Q4734892-A89EB748-30C4-4863-8A36-E0C4102C2098
wd:statement/Q4734892-AE270FBF-F82A-4A49-AD75-EBCCF752AFEB
wd:statement/Q4734892-B0663BE8-D470-46AA-A180-C2E3679716F5
wd:statement/Q4734892-B495222B-F660-4F45-9447-A097A5E1EBD9
wd:statement/Q4734892-C2C55322-3DC4-43E7-BBCB-0A782041C65E
wd:statement/Q4734892-D23DDBDF-9005-42C1-B2AB-01F32F5473F8
wd:statement/Q4734892-D9ABBF4F-95B6-40D0-BEDA-B6DE01E45E74
wd:statement/Q4734892-E166FA38-D771-4AE5-9257-571FFBDDD0BB
wd:statement/Q4734892-E294ED05-B9C8-481B-9A17-326B26AF08BB
wd:statement/Q4734892-E800C76E-E558-43DD-A8C3-15B2535144FA
wd:statement/Q4734892-ED7B4F6E-0819-43E5-9AD5-9FAE7AEF7173
p:P692 wd:statement/Q4734892-B243FCAB-D130-4337-9CCB-8923D4993922
p:P702 wd:statement/Q4734892-00194E79-8705-44D9-B1C4-F2A3C4DD75D9
p:P703 wd:statement/Q4734892-B20E63F7-13CC-49FB-A923-C7B3C9BAD61F
p:P705 wd:statement/Q4734892-5A4D9F23-6137-4E18-910D-1676191D3049
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/P08913>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_000672>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1HLL>
<https://rdf.wwpdb.org/pdb/1HO9>
<https://rdf.wwpdb.org/pdb/1HOD>
<https://rdf.wwpdb.org/pdb/1HOF>
wdt:P129 levonordefrin
epinephrine
norepinephrine
WB-4101
(−)-ephedrine
apomorphine
apraclonidine hydrochloride
dipivefrin hydrochloride
oxymetazoline hydrochloride
phenoxybenzamine hydrochloride
dexmedetomidine hydrochloride
chlorpromazine
dexmedetomidine
clonidine
yohimbine
bromocriptine
tolazoline
piribedil
pergolide
lurasidone
oxymetazoline
phentolamine
mirtazapine
cabergoline
lisuride
prazosin
xylazine
apraclonidine
brl-44408
guanabenz
guanfacine
brimonidine
spiroxatrine
α-yohimbine
terguride
wdt:P31 protein
wdt:P352 "P08913"
wdt:P361 Alpha 2A adrenoceptor
GPCR, rhodopsin-like, 7TM, protein family
wdt:P527 GPCR, rhodopsin-like, 7TM
wdt:P637 "NP_000672"
wdt:P638 "1HLL"
"1HO9"
"1HOD"
"1HOF"
wdt:P680 protein homodimerization activity
protein heterodimerization activity
protein kinase binding
signal transducer activity
G protein-coupled receptor activity
thioesterase binding
heterotrimeric G-protein binding
epinephrine binding
norepinephrine binding
adrenergic receptor activity
protein binding
alpha2-adrenergic receptor activity
alpha-2C adrenergic receptor binding
alpha-1B adrenergic receptor binding
wdt:P681 integral component of membrane
membrane
integral component of plasma membrane
basolateral plasma membrane
receptor complex
plasma membrane
cytoplasm
wdt:P682 Ras protein signal transduction
positive regulation of cell population proliferation
G protein-coupled receptor signaling pathway
positive regulation of cell migration
activation of protein kinase B activity
glucose homeostasis
positive regulation of MAPK cascade
regulation of insulin secretion
negative regulation of lipid catabolic process
platelet activation
negative regulation of norepinephrine secretion
negative regulation of epinephrine secretion
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
positive regulation of cytokine production
regulation of vasoconstriction
adenylate cyclase-activating G protein-coupled receptor signaling pathway
Rho protein signal transduction
activation of protein kinase activity
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
negative regulation of insulin secretion
negative regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of calcium ion-dependent exocytosis
positive regulation of MAP kinase activity
positive regulation of epidermal growth factor-activated receptor activity
cellular response to hormone stimulus
negative regulation of calcium ion transport
negative regulation of calcium ion transmembrane transporter activity
actin cytoskeleton organization
positive regulation of wound healing
positive regulation of potassium ion transport
positive regulation of membrane protein ectodomain proteolysis
intestinal absorption
adenylate cyclase-activating adrenergic receptor signaling pathway
receptor transactivation
adrenergic receptor signaling pathway
regulation of smooth muscle contraction
adenylate cyclase-inhibiting adrenergic receptor signaling pathway
phospholipase C-activating adrenergic receptor signaling pathway
signal transduction
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20ADRA2A%20209869%20at%20fs.png>
wdt:P702 ADRA2A
wdt:P703 man
wdt:P705 "ENSP00000280155"
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