|
rdfs:label
|
"G protein-coupled receptor kinase 2"@en
"Quinase do receptor beta adrenérgico"@pt
|
|
skos:altLabel
|
"G-protein coupled receptor kinase 2"@en
|
|
"GRK2"@en
|
|
"adrenergic beta receptor kinase 1"@en
|
|
"beta-ARK-1"@en
|
|
"beta-adrenergic receptor kinase 1"@en
|
|
schema:description
|
"Protein in Homo sapiens"@de
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteïne in G protein-coupled receptor kinase 2"@nl
"protèin"@ace
"protéine"@fr
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
|
|
schema:dateModified
|
"2026-07-23T15:32:56+00:00"^^xsd:dateTime
|
|
schema:version
|
2521705344
|
|
wikibase:identifiers
|
17
|
|
wikibase:sitelinks
|
0
|
|
wikibase:statements
|
76
|
|
p:P129
|
wd:statement/Q4897285-16405245-0264-4822-8002-1F5465AEB50B
|
|
p:P2888
|
wd:statement/Q4897285-E0CB9513-C6ED-4911-924B-CD184349BFCE
|
|
p:P31
|
wd:statement/Q4897285-450F9431-04E0-4D71-8B6A-387AB87AD287
|
|
p:P352
|
wd:statement/Q4897285-42A764E4-B0D3-4AA6-8233-4F893B2B6EB2
|
|
p:P361
|
wd:statement/Q4897285-0A2DCC9D-4921-48B1-848B-44A34CE88CCF
|
|
wd:statement/Q4897285-148E273E-B329-4D8F-96B9-81EB0B8DEA92
|
|
wd:statement/Q4897285-2979FD9B-9182-442E-9FC8-E9B49581AC2F
|
|
wd:statement/Q4897285-5E4909D5-0F1D-48E6-9C8B-7234B3CC3FD0
|
|
wd:statement/Q4897285-73AB3D67-1DD0-47D1-AB3C-8B1ED0615134
|
|
wd:statement/Q4897285-82943FB1-47B8-423E-AF61-470792AF2482
|
|
wd:statement/Q4897285-AA138D0A-FB32-48FD-B2B9-C2709801491C
|
|
wd:statement/Q4897285-CCC2CF00-2F61-4471-894E-7C772817B878
|
|
wd:statement/Q4897285-D68D056D-1EFE-4AC1-AF7D-3AE21906D11C
|
|
wd:statement/Q4897285-D7264B95-3753-4CFE-946A-475932A9F50F
|
|
p:P486
|
wd:statement/Q4897285-93ae3a5b-49c2-d08a-6634-8e1028f6e1f9
|
|
p:P527
|
wd:statement/Q4897285-07FCD70E-0DEC-46F9-BEE6-BE2449336D9C
|
|
wd:statement/Q4897285-0DEC4591-DE04-4C88-86E3-AD30B52093E1
|
|
wd:statement/Q4897285-1AA1E69B-2D9C-47D5-A27D-58A1E9095159
|
|
wd:statement/Q4897285-9E8DBA69-160D-4E7E-AF96-E26BD82D72EA
|
|
wd:statement/Q4897285-B4DF3456-CA94-4527-BF8F-8EDB962A8AB8
|
|
wd:statement/Q4897285-DAB5B584-00DC-481C-93D5-AE906DF682E4
|
|
p:P591
|
wd:statement/Q4897285-A2574CEC-6522-44D9-82F0-BF3738574DAB
|
|
wd:statement/Q4897285-C4FDA2F1-0A68-4386-BB3C-B689265F948E
|
|
p:P637
|
wd:statement/Q4897285-1008A5C9-F09D-4B17-9E1A-47E266126F10
|
|
wd:statement/Q4897285-58C96D80-6E0B-45DE-8889-D45FC9C267E8
|
|
wd:statement/Q4897285-9E052396-C5B0-4ED3-A095-3C001FF6F4D1
|
|
p:P638
|
wd:statement/Q4897285-02829556-6D63-44A1-894F-F31A52295BF8
|
|
wd:statement/Q4897285-1542F5A7-4DB0-49C5-8A77-5D3EF79D8E5C
|
|
wd:statement/Q4897285-334338C7-D99E-460F-B724-041F12FC7A25
|
|
wd:statement/Q4897285-4171C6E6-882F-45C1-94F0-F30F6F9B2A43
|
|
wd:statement/Q4897285-6DB4B594-5CDD-4C3D-903F-20696C65804E
|
|
wd:statement/Q4897285-88674040-5E97-4572-A366-99302EAFD3E9
|
|
wd:statement/Q4897285-AC35CF2E-7107-4BA5-93DC-911A0476FC6B
|
|
wd:statement/Q4897285-DE578883-05B1-44F4-A5E8-FDF6E88EBC58
|
|
p:P672
|
wd:statement/Q4897285-283fb41e-4631-20b0-446b-0e4f82d3088d
|
|
wd:statement/Q4897285-47eed13d-49b8-3cca-3c68-c771e6087ee7
|
|
p:P680
|
wd:statement/Q4897285-03973F48-4913-4EBE-A32F-9AAB96D85327
|
|
wd:statement/Q4897285-0B6E2191-CC4C-4558-8E1E-62A0D06D8D11
|
|
wd:statement/Q4897285-12569A02-0996-4669-AEFC-CAA06B496A83
|
|
wd:statement/Q4897285-1336E569-2FD4-42DE-A592-60E228A6DB87
|
|
wd:statement/Q4897285-3F7C0E2F-3A47-4048-AEA5-600FF72E7D4A
|
|
wd:statement/Q4897285-74ED5CE3-A52F-40BB-9DF5-38685A4C6E1E
|
|
wd:statement/Q4897285-83095E1E-E8CC-410D-A4E9-27ABE0822782
|
|
wd:statement/Q4897285-9343FE46-C95F-48E2-B0F1-B5C958F13517
|
|
wd:statement/Q4897285-9565DC5D-0390-48B8-9A08-F4FCF17BC943
|
|
wd:statement/Q4897285-AADBA020-7D3A-466E-9E33-9F20E65BC072
|
|
wd:statement/Q4897285-D4AD9AB0-CF7C-45AA-A08A-5CEC41B63857
|
|
p:P681
|
wd:statement/Q4897285-1DE226DF-6BF9-4F87-803C-24592EC4D6F0
|
|
wd:statement/Q4897285-4AEC9C33-2ED5-4F73-B384-D59719EFC2BD
|
|
wd:statement/Q4897285-5BA5E5C4-972C-4ED4-BCD2-6761EDCA036C
|
|
wd:statement/Q4897285-657144A4-59E4-4A21-8C97-232E4B3A0B6F
|
|
wd:statement/Q4897285-7EC924E2-629A-4A05-AA38-F223D9958C39
|
|
wd:statement/Q4897285-E650E043-4E7E-4EC2-9055-3AB4FB401603
|
|
p:P682
|
wd:statement/Q4897285-0559E894-CEC4-42E4-AB1D-E03A42CDCEDA
|
|
wd:statement/Q4897285-16ADAF93-E1DB-46F0-8043-451E24A0A9AE
|
|
wd:statement/Q4897285-249C9DF3-E6FC-4941-B16F-58AC2F2165F0
|
|
wd:statement/Q4897285-33DE62E1-362F-4B59-8661-EA26B8F8A50B
|
|
wd:statement/Q4897285-34D40BDF-D2B3-4ACE-8383-100734790474
|
|
wd:statement/Q4897285-40AD375B-939C-498F-A3E4-9C5CFEDE1E65
|
|
wd:statement/Q4897285-49DA1673-503E-46E1-84FC-4C3673389E6F
|
|
wd:statement/Q4897285-50E86952-E46A-46F0-B323-D87629DFE60C
|
|
wd:statement/Q4897285-5E1FD3AF-AE3B-49E7-AB1B-ED48FBDE7AEA
|
|
wd:statement/Q4897285-6E7274FD-75C3-4398-9197-151135AFC378
|
|
wd:statement/Q4897285-8D5488C4-B7B2-40BF-B6AF-071A4296F318
|
|
wd:statement/Q4897285-9D4774BD-899D-4A97-A176-988DE7B43C1C
|
|
wd:statement/Q4897285-C5F82A49-4908-4662-83E6-677732513A48
|
|
wd:statement/Q4897285-CDB1DE43-1BE0-4111-91E8-6E7A34E21408
|
|
wd:statement/Q4897285-DDE32145-A241-4ACA-AABA-B11DBBE82C67
|
|
wd:statement/Q4897285-F1262872-067B-43D8-BACB-D0B7E8EC73F1
|
|
wd:statement/Q4897285-F20188F4-AF1C-410E-B0FA-A1E14AEB7EA3
|
|
wd:statement/Q4897285-F551CE16-B2EB-4EE4-82E0-F91D852A57DA
|
|
p:P692
|
wd:statement/Q4897285-0A0E7504-72B6-4B2D-801C-B5C3D874C700
|
|
p:P702
|
wd:statement/Q4897285-DE5D416B-5C84-4D58-BF29-6899C83BE729
|
|
p:P703
|
wd:statement/Q4897285-31D1D82F-8EA2-4170-A8DB-634EA7BF1893
|
|
p:P705
|
wd:statement/Q4897285-06127D73-05A0-4B85-81DE-523891552AC6
|
|
wd:statement/Q4897285-6FCE0B7F-822F-42D6-8678-E676825BF278
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P25098>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/D054769>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001610>
|
|
<http://purl.uniprot.org/refseq/XP_011543075>
|
|
<http://purl.uniprot.org/refseq/XP_024304144>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/1BAK>
|
|
<https://rdf.wwpdb.org/pdb/3CIK>
|
|
<https://rdf.wwpdb.org/pdb/3KRW>
|
|
<https://rdf.wwpdb.org/pdb/3KRX>
|
|
<https://rdf.wwpdb.org/pdb/3V5W>
|
|
<https://rdf.wwpdb.org/pdb/4MK0>
|
|
<https://rdf.wwpdb.org/pdb/4PNK>
|
|
<https://rdf.wwpdb.org/pdb/5HE1>
|
|
p:direct-normalized/P672
|
<http://id.nlm.nih.gov/mesh/D08.811.913.696.620.682.700.364.049.200>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.476.563.364.049.200>
|
|
wdt:P129
|
balanol
|
|
wdt:P2888
|
<http://purl.uniprot.org/uniprot/P25098>
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P25098"
|
|
wdt:P361
|
Protein kinase-like domain superfamily
|
|
GPCR kinase
|
|
PH-like domain superfamily
|
|
RGS domain superfamily
|
|
regulator of G protein signalling
|
|
AGC-kinase, C-terminal domain, protein family
|
|
Protein kinase domain, protein family
|
|
pleckstrin homology domain, protein family
|
|
Serine/threonine-protein kinase, active site, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P486
|
"D054769"
|
|
wdt:P527
|
AGC-kinase, C-terminal
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
RGS domain
|
|
pleckstrin homology domain
|
|
serine/threonine-protein kinase, active site
|
|
wdt:P591
|
"2.7.11.15"
|
|
"2.7.11.16"
|
|
wdt:P637
|
"NP_001610"
|
|
"XP_011543075"
|
|
"XP_024304144"
|
|
wdt:P638
|
"1BAK"
|
|
"3CIK"
|
|
"3KRW"
|
|
"3KRX"
|
|
"3V5W"
|
|
"4MK0"
|
|
"4PNK"
|
|
"5HE1"
|
|
wdt:P672
|
"D08.811.913.696.620.682.700.364.049.200"
|
|
"D12.776.476.563.364.049.200"
|
|
wdt:P680
|
protein serine/threonine kinase activity
|
|
ATP binding
|
|
protein kinase activity
|
|
transferase activity
|
|
nucleotide binding
|
|
kinase activity
|
|
alpha-2A adrenergic receptor binding
|
|
G protein-coupled receptor kinase activity
|
|
Edg-2 lysophosphatidic acid receptor binding
|
|
beta-adrenergic receptor kinase activity
|
|
protein binding
|
|
wdt:P681
|
membrane
|
|
cilium
|
|
cytosol
|
|
plasma membrane
|
|
cytoplasm
|
|
wdt:P682
|
G protein-coupled receptor signaling pathway
|
|
peptidyl-serine phosphorylation
|
|
receptor internalization
|
|
peptidyl-threonine phosphorylation
|
|
cardiac muscle contraction
|
|
regulation of the force of heart contraction
|
|
G protein-coupled acetylcholine receptor signaling pathway
|
|
desensitization of G protein-coupled receptor signaling pathway
|
|
negative regulation of the force of heart contraction by chemical signal
|
|
tachykinin receptor signaling pathway
|
|
positive regulation of catecholamine secretion
|
|
negative regulation of striated muscle contraction
|
|
phosphorylation
|
|
viral genome replication
|
|
viral entry into host cell
|
|
development of the heart
|
|
protein phosphorylation
|
|
signal transduction
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20ADRBK1%2038447%20at%20fs.png>
|
|
wdt:P702
|
GRK2
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000312262"
|
|
"ENSP00000434126"
|
