SHMARQL

checkpoint kinase 2

<http://www.wikidata.org/entity/Q5011104>

mammalian protein found in Homo sapiens
rdfs:label
"checkpoint kinase 2"@en
skos:altLabel
"CHEK2"@en
"CHK2 checkpoint homolog"@en
"Hucds1"@en
"cds1 homolog"@en
"checkpoint-like protein CHK2"@en
"hCds1"@en
"serine/threonine-protein kinase Chk2"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-07-23T15:33:08+00:00"^^xsd:dateTime
schema:version 2521705427
wikibase:identifiers 84
wikibase:sitelinks 0
wikibase:statements 157
p:P2888 wd:statement/Q5011104-A26A475E-5466-4906-935C-B8C64E615C75
p:P2892 wd:statement/Q5011104-0E619692-5058-4AF8-8303-EFE473D578C8
p:P31 wd:statement/Q5011104-01D1A570-9820-4645-A91F-912417AB2EFA
p:P352 wd:statement/Q5011104-4C6084B0-44F1-4A26-B798-EF5E05E6D7D7
p:P361 wd:statement/Q5011104-03915B77-0D45-44ED-A43D-5D23073E4C48
wd:statement/Q5011104-50401520-8E93-47B5-9B50-CE26A84B3FFC
wd:statement/Q5011104-7166BC0A-31C7-4D0C-BAF3-51217309B6FA
wd:statement/Q5011104-73C4EC7A-50CF-45FE-BAB8-9C4AA7A90ED9
wd:statement/Q5011104-E640466D-DE05-4A2D-920D-86F246C60921
p:P486 wd:statement/Q5011104-8BC896E4-BAD6-422C-BBEA-535D6E0DD11B
p:P527 wd:statement/Q5011104-43ED4B17-2A58-4FF9-B258-29D48CBAE7E5
wd:statement/Q5011104-C4BB4049-78FF-45C8-918C-3AA20407A931
wd:statement/Q5011104-E993BFE0-0769-4FEA-8966-2318E2B28A3C
p:P591 wd:statement/Q5011104-97C378EB-D776-4E46-ABF9-7FA0FC2ECCF4
p:P637 wd:statement/Q5011104-11CB0F26-B84E-4698-BA18-8D74459DBF45
wd:statement/Q5011104-41870868-B3CA-4011-9A07-37B917B807E1
wd:statement/Q5011104-5C6062C9-9F2D-4CFE-A4C3-5BB066198596
wd:statement/Q5011104-5E947100-39E8-4D99-9E30-0133432E3AEB
wd:statement/Q5011104-6ED0D0B6-33E1-467F-9C1F-367EBD72058C
wd:statement/Q5011104-7426707E-3511-43FB-A557-355C5E5F4B64
wd:statement/Q5011104-810B3576-E52C-41E8-96B2-2A1B5F21604D
wd:statement/Q5011104-8936F9B3-2DDD-46AC-AD94-C4FE23DB659F
wd:statement/Q5011104-9BD9419E-A7AC-4503-AAFC-278711763375
wd:statement/Q5011104-A232D4E8-2580-4725-B704-9F05CF15DD1F
wd:statement/Q5011104-A2A4E1D2-572F-47F7-AEDD-71B3F6817723
wd:statement/Q5011104-B02053F5-895B-420A-8460-A7E0217A3225
wd:statement/Q5011104-C238D23B-5915-4CEB-96B0-A38E442DC885
wd:statement/Q5011104-C97B4435-BCDB-4CEB-937A-74DD6EB00F68
wd:statement/Q5011104-DC89CA75-B344-4586-B940-132FF24C0FE4
wd:statement/Q5011104-EA6638A6-F081-4894-942B-25CAC9D43A39
wd:statement/Q5011104-EAB27747-7388-4F50-A36E-5082D5B5F70D
p:P638 wd:statement/Q5011104-0252273A-254B-4416-A396-B46797B0A442
wd:statement/Q5011104-027BF167-77A4-4A11-A649-571BCDFECB1D
wd:statement/Q5011104-04D865C6-FB71-47C6-AFB6-145F9FA22575
wd:statement/Q5011104-0D991EED-4335-452F-A152-B371F07C1EB9
wd:statement/Q5011104-0F296DF2-A1FE-4E4A-934B-E20CA1BB153F
wd:statement/Q5011104-1289DC98-24DF-45F5-8A93-AA3030E453F1
wd:statement/Q5011104-158C865A-AA4E-4D76-9E4F-9406F8F67DF3
wd:statement/Q5011104-350AB86F-8BE9-424D-A64C-D3C050D5BBB1
wd:statement/Q5011104-456B8E07-11E7-4F3A-B1BD-832E81EDDE78
wd:statement/Q5011104-4821E738-88CB-4459-BD2D-A115CB2EC749
wd:statement/Q5011104-4920E3E8-5F52-42F1-8D14-D25E4E00FD1F
wd:statement/Q5011104-50DF13E7-ACF6-4EE9-95B6-4D9EDB2C9656
wd:statement/Q5011104-52B035DB-714C-42D0-B651-C02BEC50B52C
wd:statement/Q5011104-55BBE4DB-75D8-4C25-9BFB-6DF27D6B5AC0
wd:statement/Q5011104-57A58582-3679-4996-B7CC-4A84B15D5D4F
wd:statement/Q5011104-631DC01C-9C36-4188-BF62-DBE6C39D0A52
wd:statement/Q5011104-67B9DB6C-E590-47C5-90EA-36841048EAA1
wd:statement/Q5011104-7500CFFB-F667-4D41-95E3-EEB08D75BD4D
wd:statement/Q5011104-79F6649D-86FB-4DA2-82AC-E36DACD501B7
wd:statement/Q5011104-7AF5D261-4462-4B04-A84A-08F1F8040FED
wd:statement/Q5011104-7CE567E3-33F6-4E96-8647-633E17FF9383
wd:statement/Q5011104-84AE3617-3B8A-43FE-8D89-C29C43269904
wd:statement/Q5011104-8F284C33-475C-4788-B4E3-090FCE07D0B7
wd:statement/Q5011104-92E234FD-A49A-4D99-A1FC-4AE5CEED2188
wd:statement/Q5011104-99886993-B01C-4DA9-B324-AFB146666036
wd:statement/Q5011104-A0D7636B-2E77-4005-B4F9-5C071C029AA1
wd:statement/Q5011104-A6AF70E6-50AA-403D-BED7-FFE9A7392C0B
wd:statement/Q5011104-AE3CC66C-77C0-4E39-87A5-BC76D855038A
wd:statement/Q5011104-B38F0E17-2329-47A8-A2BD-20FE4355C418
wd:statement/Q5011104-C31A02BC-EAB0-4789-B119-ABF03E90E732
wd:statement/Q5011104-C846E562-4717-4D95-83D3-D533AE592222
wd:statement/Q5011104-CC4A261A-A9BF-4F71-A1EA-D05FF1E42868
wd:statement/Q5011104-D7985F60-CB45-4002-92CA-9F680B13CFAE
wd:statement/Q5011104-DBEC920E-972D-4A8F-8792-D42D3251025F
wd:statement/Q5011104-E6711B60-F9CA-4E35-8308-8F9041BF923A
wd:statement/Q5011104-F462C02D-6DD3-4165-8DB4-C2DD60557BCA
wd:statement/Q5011104-FA2478CD-C50D-4869-9BD7-1F94B87FBDE7
p:P646 wd:statement/Q5011104-6687C756-E9DB-4678-A942-13DD559055FD
p:P672 wd:statement/Q5011104-bbf6f0f4-429d-2840-510d-74846b007813
wd:statement/Q5011104-c7c98ad3-4e10-fb0e-e040-28d6b2142c4a
p:P680 wd:statement/Q5011104-09820F8D-DBF3-455D-8E63-5B901BE6CC5D
wd:statement/Q5011104-199ABE70-FA3C-4E4C-B2B1-16450E22AA3F
wd:statement/Q5011104-1E688034-49D7-4F80-9630-6DE9F8E94F7A
wd:statement/Q5011104-4F989F43-6FF5-41D5-8C2F-009D7EF06E4D
wd:statement/Q5011104-51A2F20B-3EE8-469D-9E1E-C90FEDD6F47C
wd:statement/Q5011104-57F9B598-15A4-4587-A946-F4DDC4DB06F5
wd:statement/Q5011104-5B0D90E2-A510-45EC-889F-E2A9CF809D64
wd:statement/Q5011104-6037DC43-9ADA-4E4C-B19D-F841C50E36F7
wd:statement/Q5011104-8043C3AC-70CF-4AEC-8665-2A3B21DC83C3
wd:statement/Q5011104-8574B3D8-6181-4C74-BE5B-AC8AD63220C8
wd:statement/Q5011104-9EC4EF04-6B0F-47DF-9D11-2B25B3631C72
wd:statement/Q5011104-CC803E9D-84D8-4141-BAB5-D0A3632087AA
wd:statement/Q5011104-EDC1E3F8-7328-475F-8C50-51B871E2C8F8
p:P681 wd:statement/Q5011104-183446BE-5A29-4DCD-BEBF-F641C8BDE0EB
wd:statement/Q5011104-64353A5C-2016-4BD4-89A7-9A3B79CD0E06
wd:statement/Q5011104-849C53C4-B48F-4B29-A4DD-ED84A994C30E
wd:statement/Q5011104-A9277741-29C1-4C17-8E5F-5445B4E498C4
wd:statement/Q5011104-B0867D6D-26BB-47FE-8DFA-328C6010212A
wd:statement/Q5011104-B6B0EFA8-4D52-423D-840D-43DEA157E041
wd:statement/Q5011104-B7CD0398-F64A-4117-A759-8BADC7FFE3DA
p:P682 wd:statement/Q5011104-01684D30-EC0A-4F69-90C3-B2C16A9595FA
wd:statement/Q5011104-084FFC6B-0043-4EEA-80BD-7931B830F680
wd:statement/Q5011104-0FE9A0AD-900E-41DF-9918-0C99F0227008
wd:statement/Q5011104-0FF6C214-6402-46A8-92E9-84A422CC9A28
wd:statement/Q5011104-10C0BECB-03D8-4563-BA92-6557B1995046
wd:statement/Q5011104-1C9E5193-CD69-4BC7-990B-52A469639041
wd:statement/Q5011104-1D1EA425-52DB-45C3-9EEA-C7B5E4001BD4
wd:statement/Q5011104-1D3C5B15-677D-477E-BA98-B9D99003F8F5
wd:statement/Q5011104-2213FA60-3AFA-4587-B7C6-1A9B5A25CC3F
wd:statement/Q5011104-2F35FFC4-DAE4-4A0B-997F-D50ADA2E4A4E
wd:statement/Q5011104-3359F5BC-1A61-42DC-B388-6AA9A3153E1A
wd:statement/Q5011104-36BDAF2D-B278-4CB9-850D-66449ACB00C5
wd:statement/Q5011104-378E7CE6-A39F-479F-B54E-599025046E18
wd:statement/Q5011104-436BAE5A-E845-415F-BD9C-FC848EEF04D3
wd:statement/Q5011104-4C768A86-8A43-453E-83D6-2CE051E49EBA
wd:statement/Q5011104-510BDF65-890F-4687-A197-FA551FA0C0FD
wd:statement/Q5011104-568934D9-E8ED-465C-844F-E92D5BBE45D1
wd:statement/Q5011104-5C997719-B463-4486-BD53-D64DB31BC59E
wd:statement/Q5011104-6462B56E-7EB7-4324-A462-58E49F6F1D8D
wd:statement/Q5011104-8D3FF605-4BE6-456E-8B99-A3863565F563
wd:statement/Q5011104-9143748E-872E-4365-B6FF-F829122F56D0
wd:statement/Q5011104-9486E1F1-7718-4164-8C38-417BEF9670A6
wd:statement/Q5011104-961F4D60-CBAB-40B2-A049-78BC686D3F09
wd:statement/Q5011104-98E14076-FEE7-44E7-95B4-60CADD3C2C4A
wd:statement/Q5011104-A0CD9D44-CA47-4BE4-80E1-D21938075787
wd:statement/Q5011104-A65E4872-4F50-496C-B94A-BB86D85B5458
wd:statement/Q5011104-AC310E6F-B825-4239-860B-7AE22DBA6680
wd:statement/Q5011104-AE2BD6FD-5B27-437E-A0A1-357F8CFACDFB
wd:statement/Q5011104-B68A3EEF-E203-4F16-A1E4-0BB718BC9B98
wd:statement/Q5011104-B9F8B2CC-4B2E-4A6C-9039-C2A7A494CB56
wd:statement/Q5011104-C2352AA7-468F-41E2-8781-3E57E958AB4A
wd:statement/Q5011104-C75C85E2-1904-4262-BCA0-069C85455803
wd:statement/Q5011104-CE7FCE05-F996-43E5-9D22-116B422AEE25
wd:statement/Q5011104-D21DFB25-B9C0-450F-9DC2-C9B2B8B7FE19
wd:statement/Q5011104-D95D0594-872A-44AE-B394-56EB38F69DC0
wd:statement/Q5011104-DD01B373-DBF8-4825-91A6-090D02E4778A
wd:statement/Q5011104-F3B9756E-B0E5-48AA-8EF7-8E65801E4305
wd:statement/Q5011104-F87636C6-D608-407E-A6C1-B04908E9286F
wd:statement/Q5011104-FB8477CF-9A6E-4A34-994E-F30428C273BE
p:P692 wd:statement/Q5011104-430B2C01-EE2A-41D7-A090-ACB386389A00
p:P702 wd:statement/Q5011104-F8A8C754-11B5-4101-9686-92091C5630DB
p:P703 wd:statement/Q5011104-F1472AF6-E6CA-4D54-BAE9-3F61FC1BD006
p:P705 wd:statement/Q5011104-0D3DBC64-D32C-4C36-83A6-F44E0733DD87
wd:statement/Q5011104-2EE9368C-9C71-452B-997A-A078C0C5AB97
wd:statement/Q5011104-349E1B91-959C-4AE2-AA36-7EAA14EA0BB0
wd:statement/Q5011104-50748DFB-415D-4CA6-8D34-5DBC8ED9003A
wd:statement/Q5011104-5C2139D1-991F-43EB-933F-7694CC8B1C7E
wd:statement/Q5011104-5D340D7C-A9AD-495F-8239-FE6FCAC5A92A
wd:statement/Q5011104-672A285C-9467-483C-B246-66DAA1080D77
wd:statement/Q5011104-780BA2E4-39D0-483D-81F1-7431407CCE9A
wd:statement/Q5011104-8583EFB8-46D5-426C-B2D2-A0A2068B973F
wd:statement/Q5011104-9DEC2811-E020-4DAE-880F-E49E3AF9341C
wd:statement/Q5011104-A6125062-1E14-4601-8397-79B798DECA9C
wd:statement/Q5011104-AD276BD4-F93E-4853-879D-EC7BB2A61340
wd:statement/Q5011104-C643EDEA-C46B-4284-A3DE-098FDF17825E
wd:statement/Q5011104-C6DBB167-819F-44C0-B0B9-28CDD7D4CF65
wd:statement/Q5011104-CDFCCF4F-71D6-4502-9799-A94BC4DFE625
wd:statement/Q5011104-D28B42A9-874A-45BC-9096-AD60054E7EC6
wd:statement/Q5011104-D76F96B6-56BE-4C41-84DD-7250FEDFC7C6
wd:statement/Q5011104-D886B85F-D3D4-4592-AE35-C6576E6044FA
wd:statement/Q5011104-DD420F88-8DD4-41EA-90DC-6631FB2BFDD6
wd:statement/Q5011104-DD42E9C4-58BB-4449-BB9F-7A7E5FFA0344
wd:statement/Q5011104-EA9016CB-2F1F-42A4-97CC-62C0DBDCF726
wd:statement/Q5011104-EAC8DAB3-FD2D-4348-80BC-79EBC2C57976
wd:statement/Q5011104-F4B5E13D-B029-433B-800D-9E36EBFE7B29
wd:statement/Q5011104-FA7DFDA5-5D65-4FD5-B29D-CA2F92E06B6A
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/O96017>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D064447>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_001005735>
<http://purl.uniprot.org/refseq/NP_001244316>
<http://purl.uniprot.org/refseq/NP_001336885>
<http://purl.uniprot.org/refseq/NP_009125>
<http://purl.uniprot.org/refseq/NP_665861>
<http://purl.uniprot.org/refseq/XP_006724177>
<http://purl.uniprot.org/refseq/XP_006724179>
<http://purl.uniprot.org/refseq/XP_011528141>
<http://purl.uniprot.org/refseq/XP_011528142>
<http://purl.uniprot.org/refseq/XP_011528143>
<http://purl.uniprot.org/refseq/XP_011528144>
<http://purl.uniprot.org/refseq/XP_011528146>
<http://purl.uniprot.org/refseq/XP_011528147>
<http://purl.uniprot.org/refseq/XP_016884049>
<http://purl.uniprot.org/refseq/XP_016884050>
<http://purl.uniprot.org/refseq/XP_024307916>
<http://purl.uniprot.org/refseq/XP_024307917>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/1GXC>
<https://rdf.wwpdb.org/pdb/2CN5>
<https://rdf.wwpdb.org/pdb/2CN8>
<https://rdf.wwpdb.org/pdb/2W0J>
<https://rdf.wwpdb.org/pdb/2W7X>
<https://rdf.wwpdb.org/pdb/2WTC>
<https://rdf.wwpdb.org/pdb/2WTD>
<https://rdf.wwpdb.org/pdb/2WTI>
<https://rdf.wwpdb.org/pdb/2WTJ>
<https://rdf.wwpdb.org/pdb/2XBJ>
<https://rdf.wwpdb.org/pdb/2XK9>
<https://rdf.wwpdb.org/pdb/2XM8>
<https://rdf.wwpdb.org/pdb/2XM9>
<https://rdf.wwpdb.org/pdb/2YCF>
<https://rdf.wwpdb.org/pdb/2YCQ>
<https://rdf.wwpdb.org/pdb/2YCR>
<https://rdf.wwpdb.org/pdb/2YCS>
<https://rdf.wwpdb.org/pdb/2YIQ>
<https://rdf.wwpdb.org/pdb/2YIR>
<https://rdf.wwpdb.org/pdb/2YIT>
<https://rdf.wwpdb.org/pdb/3I6U>
<https://rdf.wwpdb.org/pdb/3I6W>
<https://rdf.wwpdb.org/pdb/4A9R>
<https://rdf.wwpdb.org/pdb/4A9S>
<https://rdf.wwpdb.org/pdb/4A9T>
<https://rdf.wwpdb.org/pdb/4A9U>
<https://rdf.wwpdb.org/pdb/4BDA>
<https://rdf.wwpdb.org/pdb/4BDB>
<https://rdf.wwpdb.org/pdb/4BDC>
<https://rdf.wwpdb.org/pdb/4BDD>
<https://rdf.wwpdb.org/pdb/4BDE>
<https://rdf.wwpdb.org/pdb/4BDF>
<https://rdf.wwpdb.org/pdb/4BDG>
<https://rdf.wwpdb.org/pdb/4BDH>
<https://rdf.wwpdb.org/pdb/4BDI>
<https://rdf.wwpdb.org/pdb/4BDJ>
<https://rdf.wwpdb.org/pdb/4BDK>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D08.811.913.696.620.682.700.145>
<http://id.nlm.nih.gov/mesh/D12.776.476.563.145>
wdt:P2888 <http://purl.uniprot.org/uniprot/O96017>
wdt:P2892 "C0296594"
wdt:P31 protein
wdt:P352 "O96017"
wdt:P361 SMAD/FHA domain superfamily
Protein kinase-like domain superfamily
Forkhead-associated (FHA) domain, protein family
Protein kinase domain, protein family
Serine/threonine-protein kinase, active site, protein family
wdt:P486 "D064447"
wdt:P527 forkhead-associated (FHA) domain
protein kinase domain
serine/threonine-protein kinase, active site
wdt:P591 "2.7.11.1"
wdt:P637 "NP_001005735"
"NP_001244316"
"NP_001336885"
"NP_009125"
"NP_665861"
"XP_006724177"
"XP_006724179"
"XP_011528141"
"XP_011528142"
"XP_011528143"
"XP_011528144"
"XP_011528146"
"XP_011528147"
"XP_016884049"
"XP_016884050"
"XP_024307916"
"XP_024307917"
wdt:P638 "1GXC"
"2CN5"
"2CN8"
"2W0J"
"2W7X"
"2WTC"
"2WTD"
"2WTI"
"2WTJ"
"2XBJ"
"2XK9"
"2XM8"
"2XM9"
"2YCF"
"2YCQ"
"2YCR"
"2YCS"
"2YIQ"
"2YIR"
"2YIT"
"3I6U"
"3I6W"
"4A9R"
"4A9S"
"4A9T"
"4A9U"
"4BDA"
"4BDB"
"4BDC"
"4BDD"
"4BDE"
"4BDF"
"4BDG"
"4BDH"
"4BDI"
"4BDJ"
"4BDK"
wdt:P646 "/m/02qf66r"
wdt:P672 "D08.811.913.696.620.682.700.145"
"D12.776.476.563.145"
wdt:P680 metal ion binding
protein serine/threonine kinase activity
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
ATP binding
protein kinase binding
protein kinase activity
transferase activity
nucleotide binding
kinase activity
protein binding
wdt:P681 nucleoplasm
PML body
telomere
nucleus
cytoplasm
Golgi apparatus
wdt:P682 apoptotic process
regulation of transcription, DNA-templated
regulation of apoptotic process
protein stabilization
transcription, DNA-templated
double-strand break repair
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
response to gamma radiation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of transcription, DNA-templated
replicative senescence
positive regulation of protein phosphorylation
peptidyl-serine phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage
peptidyl-threonine phosphorylation
cellular response to gamma radiation
DNA damage induced protein phosphorylation
DNA damage checkpoint signaling
signal transduction in response to DNA damage
regulation of protein catabolic process
mitotic spindle assembly
cell division
cell cycle
DNA repair
response to glycoside
negative regulation of DNA damage checkpoint
G2/M transition of mitotic cell cycle
positive regulation of anoikis
regulation of signal transduction by p53 class mediator
mitotic DNA damage checkpoint signaling
cellular response to bisphenol A
phosphorylation
protein autophosphorylation
protein phosphorylation
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20CHEK2%20210416%20s%20at%20fs.png>
wdt:P702 CHEK2
wdt:P703 man
wdt:P705 "ENSP00000329012"
"ENSP00000372006"
"ENSP00000372023"
"ENSP00000381099"
"ENSP00000384835"
"ENSP00000384919"
"ENSP00000385747"
"ENSP00000386087"
"ENSP00000387451"
"ENSP00000390244"
"ENSP00000394430"
"ENSP00000396903"
"ENSP00000397478"
"ENSP00000402225"
"ENSP00000403659"
"ENSP00000404400"
"ENSP00000404567"
"ENSP00000408065"
"ENSP00000412901"
"ENSP00000416721"
"ENSP00000483777"
"ENSP00000496928"
"ENSP00000497000"
"ENSP00000497699"
Download as:
TurtleJSON-LDRDF/XML
data from SPARQL profile: Wikidata