SHMARQL

histone deacetylase 1

<http://www.wikidata.org/entity/Q5629167>

mammalian protein found in Homo sapiens
rdfs:label
"histone deacetylase 1"@en
skos:altLabel
"HDAC1"@en
"reduced potassium dependency, yeast homolog-like 1"@en
"uniprot:Q13547"@en
schema:description
"mammalian protein found in Homo sapiens"@en
schema:dateModified "2026-07-23T15:35:29+00:00"^^xsd:dateTime
schema:version 2521706330
wikibase:identifiers 13
wikibase:sitelinks 0
wikibase:statements 150
p:P129 wd:statement/Q5629167-17D9B9BF-9E37-4AA8-8FA4-9896DF946CFE
wd:statement/Q5629167-240BA7C5-C642-4E8C-BC48-D4A5FE65EEC7
wd:statement/Q5629167-306A93E2-C2EA-4FF8-9453-E0E32C5E7429
wd:statement/Q5629167-3CE44FE1-C19F-4ACA-AF14-A9AAC0732195
wd:statement/Q5629167-4FCEB980-E060-443B-A66C-16A3ACE0EE5B
wd:statement/Q5629167-50A37804-E91A-4A9D-893D-ACA39E544B6D
wd:statement/Q5629167-5B8C1A3B-6FBF-4378-B591-A3E43C46ED45
wd:statement/Q5629167-68119C06-95B6-4BD3-A8D3-F21C4299ABC6
wd:statement/Q5629167-6F53670D-3D1C-4632-9654-009EE9A19618
wd:statement/Q5629167-8B4D9757-E67D-45C1-8A7A-C79FE885A52A
wd:statement/Q5629167-948E11D0-5A37-485C-AEB5-64A329944E4B
wd:statement/Q5629167-ACF03238-0096-4B40-B14F-57C2734BD213
wd:statement/Q5629167-C9CA7C78-F05A-4E33-A048-9D870612EFCF
wd:statement/Q5629167-D009764A-D854-4246-BC03-13FF3ABBE267
wd:statement/Q5629167-DD114306-CAF2-42F8-9CCB-EF0A5FF9C098
wd:statement/Q5629167-E4311B97-F789-4DBC-A1DC-5CE2741FFEBD
wd:statement/Q5629167-EAB31C1A-9734-4933-9F1F-AA21DE312A03
wd:statement/Q5629167-EC936F49-B759-4EFD-A92E-82102FA0F746
wd:statement/Q5629167-F3868208-767E-4689-AD21-7FC76A664EE4
p:P2888 wd:statement/Q5629167-B1CDD6B5-21EE-4AA3-83B7-112494BAB146
p:P2892 wd:statement/Q5629167-52D0A7ED-802B-4325-AC6A-6B4EAE901033
p:P31 wd:statement/Q5629167-A2012892-B633-4AC3-BF62-92ADC62C1331
p:P352 wd:statement/Q5629167-1FB8B79A-5180-4A78-9733-20863DF463C8
p:P361 wd:statement/Q5629167-115FFF64-E457-4D52-A2C3-FA89FBF03FBB
wd:statement/Q5629167-22E24E13-9C7B-454F-B9A5-8F151C330B26
wd:statement/Q5629167-35B34426-D88E-4FF4-9F6D-2B03CA458DE6
wd:statement/Q5629167-7E5C729A-E5B0-4150-8DEB-0F26508DAD5E
p:P486 wd:statement/Q5629167-7A2F479B-E32D-4F28-80E9-7DDDC30FDF4F
p:P527 wd:statement/Q5629167-92A317BD-CA6D-4D77-B154-D69F65DF5146
p:P591 wd:statement/Q5629167-B6339A5D-3E67-4986-846E-E66BD2787976
p:P637 wd:statement/Q5629167-09FB1AB0-62A3-4D96-8B09-8217FD39DABA
wd:statement/Q5629167-6C200FA4-FB40-4273-BA0E-5BC11E135C94
p:P638 wd:statement/Q5629167-66138C71-F04B-4569-AF4A-D56A4A07D3B6
wd:statement/Q5629167-94181FDD-D9D8-44B6-8CA9-676A0275AB43
p:P672 wd:statement/Q5629167-66da0389-4aa6-8fb7-fb03-4eeca46ed512
wd:statement/Q5629167-a3ce479c-44f0-73da-1f25-2a95e2510584
wd:statement/Q5629167-e0452f80-49da-607b-257e-845f36604e39
wd:statement/Q5629167-f8d9872a-4c4b-f00b-5ecb-3f1411e96020
p:P680 wd:statement/Q5629167-00C74D4C-B193-4BD3-A808-60452B8E67FF
wd:statement/Q5629167-186B8CE4-CA65-436F-9F7F-15AAA73B8368
wd:statement/Q5629167-1AC04F9E-56FA-419B-B39D-9A3B071603AC
wd:statement/Q5629167-1B08F7A4-37DB-4A28-BDCD-61A20F4F5871
wd:statement/Q5629167-2900594A-D447-415E-8DF3-D43FC0744C8A
wd:statement/Q5629167-422A6FAE-1382-40C8-915C-F9C1E98D57D1
wd:statement/Q5629167-46A2A672-6CE3-4861-BD8A-921EDA34C02F
wd:statement/Q5629167-4E3018D9-9D27-4D1C-82BB-8150F6A056CF
wd:statement/Q5629167-55C7C26B-7340-4038-80CE-F03FB350715B
wd:statement/Q5629167-5FA44F68-DCD2-40EE-A52F-92DE06A11929
wd:statement/Q5629167-688C8FFE-8509-4181-86A7-19861586FD23
wd:statement/Q5629167-6C5F7E22-E602-41E6-BDCF-4313EEEE2216
wd:statement/Q5629167-6D0C426B-1950-4C7E-9F73-E26E6D4F0817
wd:statement/Q5629167-77020B80-F6AC-4440-AB58-EB4DA086DE5F
wd:statement/Q5629167-79A1F0C2-D73E-44D2-9ECB-A687BDCB902D
wd:statement/Q5629167-7A51AE4F-3970-4F79-8750-518FC7DF9AEF
wd:statement/Q5629167-7B87B093-3074-4F9E-8F3B-390738C12896
wd:statement/Q5629167-81058252-6A14-4185-8FD1-DB29316AD4CF
wd:statement/Q5629167-9DABAD0C-04D6-4AF5-AB33-0D666DCF68A8
wd:statement/Q5629167-9EEADBFD-D787-4C16-B3ED-8FAA43396E8E
wd:statement/Q5629167-AD55A3F9-9FB2-4AD2-8203-D7A20F744A1B
wd:statement/Q5629167-B07B5963-2AE9-4ECA-A28D-BDAA3E648275
wd:statement/Q5629167-B1CC9279-3469-4F87-8C38-BE49E6C284FA
wd:statement/Q5629167-B6F24B50-6E66-4636-9C26-28BAFD0D25CD
wd:statement/Q5629167-D2F5DE02-59D2-4A81-9AF4-CC3719078466
wd:statement/Q5629167-DED9913C-9E18-4ECB-8CB2-87964B57EC5D
wd:statement/Q5629167-E16DABFF-AF1B-4BC2-83CC-F198EF78CEAD
wd:statement/Q5629167-E9C5E6EB-1611-4DB2-8F2D-76978CE5582E
wd:statement/Q5629167-ED0B7AAF-FBD6-4CE3-963C-0EDA4E9DDB84
wd:statement/Q5629167-EEEFB05C-05F3-4D9C-A14C-9C3C1154DA21
wd:statement/Q5629167-FC147F99-3F3F-4392-BE19-96FBC2DB01E5
wd:statement/Q5629167-FCF8D14D-B88E-4095-A009-F19C2A8E7E5E
wd:statement/Q5629167-FE0D70A5-F270-45BA-8620-1C20A24FDC3D
p:P681 wd:statement/Q5629167-003AA6A8-ECCE-468F-AF50-D7EC64DCAA14
wd:statement/Q5629167-10DF64E9-0B50-457E-8D93-A33236DF29C0
wd:statement/Q5629167-2433080F-E836-4FFB-A882-B4029CE6BEA5
wd:statement/Q5629167-327F538F-BA78-4901-B298-55BED9B3E3D3
wd:statement/Q5629167-3D416F64-919F-4128-8F4C-2D79F8E40707
wd:statement/Q5629167-41027CE8-2AD0-4A7F-B42F-E509F1A109DD
wd:statement/Q5629167-64258DBB-D3ED-4055-8E52-D6C711F22524
wd:statement/Q5629167-8711AA91-F7E6-4916-AD65-E7E35D2B1B18
wd:statement/Q5629167-8BA378DC-EFAC-4A18-8C84-A9AB0695F7CE
wd:statement/Q5629167-9C01279A-6260-40E0-8A84-FD4F8DE55145
wd:statement/Q5629167-A0D37922-0C64-47CA-94CD-3C900F253724
wd:statement/Q5629167-B5E9B1CD-47F1-4D5A-A0F5-B7A75187782A
wd:statement/Q5629167-B981343B-DA0F-48E7-8733-41AD93E60E95
wd:statement/Q5629167-CEB8EDF5-45A1-40AD-8EC6-082CC991858D
wd:statement/Q5629167-CFD44F0A-201B-4F68-89C9-5AC2896AD214
wd:statement/Q5629167-F0E20A9E-9998-436B-96D8-DB7CFE7B888E
p:P682 wd:statement/Q5629167-00E52B92-B670-49A5-A04B-CD37EA7CB497
wd:statement/Q5629167-0F133AB0-D7D0-419B-8683-4545785FB2DE
wd:statement/Q5629167-15763475-1E14-4BCC-A554-0739B6FD3795
wd:statement/Q5629167-1C42BE72-F36A-409D-9FB4-658FFC374D00
wd:statement/Q5629167-1C63221A-508B-49AB-882D-6517B8EB4F6B
wd:statement/Q5629167-21D8D114-09F5-496D-8B5A-F26E89294201
wd:statement/Q5629167-22DFCC79-8120-4D18-B9F5-24ADACB8B7B2
wd:statement/Q5629167-24CC39D2-5C7A-4030-9670-D3F3FFEB969F
wd:statement/Q5629167-250B23A6-FDBA-4612-85DF-E3FBD1EEDD2A
wd:statement/Q5629167-2891155A-D664-480A-BA8F-986EBCF1D11B
wd:statement/Q5629167-2A8E78A1-B53F-4A7D-A392-EF6105981233
wd:statement/Q5629167-2D996CBB-A7F9-4E5A-9986-FECD3B2B4277
wd:statement/Q5629167-2FECBF48-C8FF-4647-92C9-21FBC8B6F121
wd:statement/Q5629167-305F375D-1758-4ED2-9EBC-A4BB61EBC553
wd:statement/Q5629167-392DE128-90EF-481E-825A-8A7905CC8C3A
wd:statement/Q5629167-406CE20B-AE93-46C5-900E-E7EA408C8346
wd:statement/Q5629167-46BDDD2B-AD57-4A1F-A3E8-1D2E18C4F867
wd:statement/Q5629167-47146823-1A0A-41C8-AF41-01B43DC757CE
wd:statement/Q5629167-48883390-EEAB-4BBD-BD42-BBAFCADFA0A9
wd:statement/Q5629167-59850D4A-C5EA-4EBE-BC13-86DE1F6800F3
wd:statement/Q5629167-5A829B4E-448F-4D11-B578-A24EAD510691
wd:statement/Q5629167-612A453C-9279-4A2A-AAB4-0FA3DA62B017
wd:statement/Q5629167-61A2DA23-8559-4FB6-9E8D-F2BB48CEB95F
wd:statement/Q5629167-67F41687-A9C8-4557-8867-9F0746A60A7A
wd:statement/Q5629167-6810BBCA-4F4B-4A9D-A245-F7DC78EBF561
wd:statement/Q5629167-6E56F702-35D1-4E1C-9D1C-279B04557550
wd:statement/Q5629167-705F096A-78FE-4167-A845-C6841E1E2032
wd:statement/Q5629167-7ACD6E10-9D5A-486C-AD20-B9170E45D091
wd:statement/Q5629167-7DC100A5-8D4E-4D23-A38D-FD1EA7CBF6EB
wd:statement/Q5629167-7FE4010E-C9C5-4031-800F-BC6176A3F9CE
wd:statement/Q5629167-81A51171-99DB-428A-9F23-3367FFEAA86C
wd:statement/Q5629167-8A24A1D5-D5F3-41EC-9890-0D5CCCCEB066
wd:statement/Q5629167-94AA2D46-BD09-42EA-BF03-6AD04388E49A
wd:statement/Q5629167-986FD865-860A-44C3-88CE-52F238C9D665
wd:statement/Q5629167-9DE9A783-A013-4F01-B265-486AB0356F54
wd:statement/Q5629167-A50548A3-203B-492A-88AD-95B62BE2852C
wd:statement/Q5629167-A51F170F-2045-424D-B4B3-D4EB6A928DEB
wd:statement/Q5629167-A54D6C2D-DC92-45F3-AFC2-F8931984F29D
wd:statement/Q5629167-B270AC93-59A4-442C-8F9E-03A2823A00CA
wd:statement/Q5629167-BDDEFB44-2244-4C45-9CCC-A088E4F292FC
wd:statement/Q5629167-BE312DB0-3739-4298-A169-E9B1C23F80F3
wd:statement/Q5629167-C40BB6B1-9A2C-4377-9E4D-E89B530C0FDE
wd:statement/Q5629167-C8EFA111-84ED-44E6-A47F-4BD82547D839
wd:statement/Q5629167-CA562572-E5FC-4DEF-9006-8EBC98F32D6B
wd:statement/Q5629167-CBC6F4FD-CDA3-42A4-A4C3-96E535B4D33B
wd:statement/Q5629167-CC587D34-7FE7-4EAD-8786-76D671A27A9E
wd:statement/Q5629167-D020EF37-0752-440B-A013-699B1FAE6B29
wd:statement/Q5629167-D26269E0-E567-4CEB-AA37-B935C445C55B
wd:statement/Q5629167-D8C85FFF-CDD0-466F-AA1E-8F33AEDA240F
wd:statement/Q5629167-DF8D76FD-695A-4262-8106-F97B94228671
wd:statement/Q5629167-E9396957-8D35-4DF9-B77A-45CC004C4F65
wd:statement/Q5629167-EA161E6D-55E9-42E0-8213-AECC735C96D0
wd:statement/Q5629167-EBF4968D-674D-425D-9336-C428FCC89F6F
wd:statement/Q5629167-ED5EE07F-33E4-4DB1-B11B-2AF3D1F05B4D
wd:statement/Q5629167-EDA72839-B0DE-443D-9A84-A4A5E8D9CFAF
wd:statement/Q5629167-F885D7B7-7682-40F7-A339-1F1DD2CA8DF3
wd:statement/Q5629167-FC3AAC0C-C777-4399-B73D-DC8BCD9AF5C2
wd:statement/Q5629167-FE857428-0518-4F7D-856B-57E4616960B6
p:P692 wd:statement/Q5629167-A1DAAE0F-50DD-4768-B6A0-01981C1A2296
p:P702 wd:statement/Q5629167-2B0BDE09-540D-4A0C-A86A-56CBF34EA83A
p:P703 wd:statement/Q5629167-35AE0530-74AF-4953-A029-9FCA1FBAE317
p:P705 wd:statement/Q5629167-CEAF3B77-5C51-4690-A79E-56DADBBFB078
wd:statement/Q5629167-ED851093-1A3A-4A53-BD5B-230AE3585891
p:direct-normalized/P352 <http://purl.uniprot.org/uniprot/Q13547>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D056284>
p:direct-normalized/P637 <http://purl.uniprot.org/refseq/NP_004955>
<http://purl.uniprot.org/refseq/XP_011539611>
p:direct-normalized/P638 <https://rdf.wwpdb.org/pdb/4BKX>
<https://rdf.wwpdb.org/pdb/5ICN>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D08.811.277.087.520.500.100>
<http://id.nlm.nih.gov/mesh/D08.811.277.087.520.750.100>
<http://id.nlm.nih.gov/mesh/D08.811.600.620.100>
<http://id.nlm.nih.gov/mesh/D08.811.600.795.100>
wdt:P129 entinostat
apicidin
pracinostat
resminostat
butyric acid
valproic acid
cudc-101
cudc-907
tacedinaline
mocetinostat
trichostatin A
givinostat
abexinostat
belinostat
panobinostat
quisinostat
romidepsin
vorinostat
wdt:P2888 <http://purl.uniprot.org/uniprot/Q13547>
wdt:P2892 "C2718309"
wdt:P31 protein
wdt:P352 "Q13547"
wdt:P361 histone deacetylases
Histone deacetylase, subgroup
Ureohydrolase domain superfamily
Histone deacetylase domain superfamily
wdt:P486 "D056284"
wdt:P527 Histone deacetylase domain
wdt:P591 "3.5.1.98"
wdt:P637 "NP_004955"
"XP_011539611"
wdt:P638 "4BKX"
"5ICN"
wdt:P672 "D08.811.277.087.520.500.100"
"D08.811.277.087.520.750.100"
"D08.811.600.620.100"
"D08.811.600.795.100"
wdt:P680 hydrolase activity
enzyme binding
DNA binding
p53 binding
chromatin binding
DNA-binding transcription factor activity
transcription factor binding
protein N-terminus binding
E-box binding
transcription corepressor activity
transcription cis-regulatory region binding
RNA polymerase II core promoter sequence-specific DNA binding
histone deacetylase binding
NF-kappaB binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
core promoter sequence-specific DNA binding
histone deacetylase activity
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
nucleosomal DNA binding
protein binding
Krueppel-associated box domain binding
deacetylase activity
promoter-specific chromatin binding
wdt:P681 soma
nucleoplasm
transcription regulator complex
transcription repressor complex
histone deacetylase complex
Sin3 complex
NuRD complex
chromatin
Sin3-type complex
cytosol
protein-containing complex
nucleus
cytoplasm
heterochromatin
wdt:P682 hippocampus development
negative regulation of apoptotic process
negative regulation of transcription by RNA polymerase II
regulation of transcription, DNA-templated
positive regulation of cell population proliferation
negative regulation of transcription, DNA-templated
transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
negative regulation of gene expression
regulation of transcription by RNA polymerase II
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of oligodendrocyte differentiation
negative regulation of canonical Wnt signaling pathway
fungiform papilla formation
endoderm development
negative regulation of androgen receptor signaling pathway
rhythmic process
viral process
epidermal cell differentiation
neuron differentiation
hair follicle placode formation
eyelid development in camera-type eye
circadian regulation of gene expression
protein deacetylation
negative regulation of myotube differentiation
histone deacetylation
histone H3 deacetylation
histone H4 deacetylation
negative regulation of intrinsic apoptotic signaling pathway
regulation of endopeptidase activity
DNA methylation-dependent heterochromatin assembly
chromatin organization
blood coagulation
circadian rhythm
negative regulation of I-kappaB kinase/NF-kappaB signaling
regulation of megakaryocyte differentiation
regulation of signal transduction by p53 class mediator
regulation of amyloid-beta clearance
beta-catenin-TCF complex assembly
chromatin remodeling
wdt:P692 <http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20HDAC1%20201209%20at%20fs.png>
wdt:P702 HDAC1
wdt:P703 man
wdt:P705 "ENSP00000362649"
"ENSP00000407859"
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