|
rdfs:label
|
"Ibrutinib"@de
"Ibrutinib"@en-ca
"Ibrutinib"@en-gb
"Ibrutinib"@es
"Ibrutinib"@it
"Ibrutinib"@pt-br
"Ibrutinib"@sh
"Ibrutinib"@sr
"Ibrutinib"@id
"ibrutinib"@en
"ibrutinib"@ca
"ibrutinib"@fr
"ibrutinib"@nl
"ibrutinib"@nn
"ibrutinib"@pt
"ibrutinib"@sl
"ibrutinibi"@fi
"İbrutinib"@tr
"ибрутиниб"@ru
"ібрутиніб"@uk
"איברוטיניב"@he
"إبروتينيب"@ar
"ایبروتینیب"@fa
"ଇବ୍ରୁଟିନିବ"@or
"イブルチニブ"@ja
"依魯替尼"@zh
"依魯替尼"@zh-hant
"依鲁替尼"@zh-cn
"依鲁替尼"@zh-hans
|
|
skos:altLabel
|
"1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one"@en
"Ibrutinib"@en
"Imbruvica®"@en
"PCI 32765"@en
"PCI-32765"@en
"PCI32765"@en
"ଇମ୍ବ୍ରୁଭିକା"@or
"依鲁替尼"@zh
|
|
schema:description
|
"Kompozé chimik"@gcr
"cheemesch Verbindung"@lb
"chemical compound"@en
"chemical compound"@en-ca
"chemical compound"@en-gb
"chemická sloučenina"@cs
"chemická zlúčenina"@sk
"chemiese verbinding"@af
"chemische Verbindung"@de
"chemische Verbindung"@de-ch
"chemische verbinding"@nl
"component quimic"@oc
"composito chimic"@ia
"compositum chemicum"@la
"compost químic"@ca
"composto chimico"@it
"composto químico"@gl
"composto químico"@pt
"composto químico"@pt-br
"composé chimique"@fr
"compuesto quimico"@an
"compuesto químico"@es
"compuestu químicu"@ast
"compus chimic"@ro
"conposto chìmego"@vec
"cumpostu chìmicu"@scn
"cyfansoddyn cemegol"@cy
"gemyske ferbining"@fy
"kediad kimiek"@br
"keemiline ühend"@et
"kemia kombinaĵo"@eo
"kemiala kompozajo"@io
"kemiallinen yhdiste"@fi
"kemisk forbindelse"@da
"kimyasal bileşik"@tr
"kjemisk forbindelse"@nb
"kjemisk sambinding"@nn
"komponim kimik"@sq
"konposatu kimiko"@eu
"senyawa kimia"@id
"związek chemiczny"@pl
"ķīmisks savienojums"@lv
"χημική ένωση"@el
"хемиско соединение"@mk
"химическое соединение"@ru
"химично съединение"@bg
"хімічна сполука"@uk
"хімічнае злучэнне"@be
"хімічнае злучэньне"@be-tarask
"քիմիական միացություն"@hy
"תרכובת כימית המשמשת כתרופה לסרטן"@he
"ترکیب شیمیایی"@fa
"مركب كيميائي"@ar
"کیٖمیٲیی مُرَکَب"@ks
"রাসায়নিক যৌগ"@bn
"ଏହା ଏକ ଔଷଧ ଯାହା ମାଣ୍ଟଲ ସେଲ ଲିମ୍ଫୋମା (ଏମସିଏଲ/MCL), କ୍ରୋନିକ୍ ଲିମ୍ଫୋସାଇଟିକ ଲ୍ୟୁକେମିଆ (ସିଏଲଏଲ/CLL) ଏବଂ ୱାଲଡେନଷ୍ଟ୍ରୋମର ମାକ୍ରୋଗ୍ଲୋବୁଲିନେମିଆ ରୋଗମାନଙ୍କର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।"@or
"രാസസംയുക്തം"@ml
"化合物"@yue
"化合物"@zh
"化合物"@zh-cn
"化合物"@zh-hans
"化合物"@zh-hant
"化合物"@zh-hk
"化合物"@zh-sg
"化合物"@zh-tw
"化合物"@zh-mo
"抗がん剤の一つ"@ja
|
|
schema:dateModified
|
"2025-11-04T06:03:41+00:00"^^xsd:dateTime
|
|
schema:version
|
2425346980
|
|
wikibase:identifiers
|
35
|
|
wikibase:sitelinks
|
19
|
|
wikibase:statements
|
78
|
|
p:P10245
|
wd:statement/Q5984881-ebc2f260-4da6-ad5d-661f-aab2b59ce0bf
|
|
p:P10283
|
wd:statement/Q5984881-B8C472B3-2829-40B0-98F1-17F17B4C0288
|
|
p:P11089
|
wd:statement/Q5984881-24A4D596-EC1B-4178-872A-BCBBCEBAFB62
|
|
p:P11143
|
wd:statement/Q5984881-868BF4A5-DCBA-4FAA-9DB0-10976178ECE1
|
|
p:P11198
|
wd:statement/Q5984881-BE0E928C-1BB1-4FD8-BD59-D801AD5C2C7E
|
|
p:P11199
|
wd:statement/Q5984881-8D57EBF2-D35F-42A9-AD51-20E48FEABEE1
|
|
p:P117
|
wd:statement/Q5984881-86b211ab-497b-66ed-2e06-f8696e124f7d
|
|
p:P129
|
wd:statement/Q5984881-7BA3B981-FED4-4158-8355-CFC61FA496D9
|
|
wd:statement/Q5984881-8C70DE05-B9A5-4B95-8A44-9A5C1CE5C941
|
|
wd:statement/Q5984881-E3744C4E-1259-4DBA-90C3-9403BE9AB1AC
|
|
p:P1579
|
wd:statement/Q5984881-90A13E5D-5193-4F2D-A69F-C98F5F11D32A
|
|
p:P2017
|
wd:statement/Q5984881-A74A0521-341E-4832-9BC4-1A61D2A01540
|
|
p:P2062
|
wd:statement/Q5984881-AE8C437A-F46D-4F6A-9A2C-703CCBBC9024
|
|
p:P2067
|
wd:statement/Q5984881-8ED29E8C-B706-472F-B126-F1C401135ED0
|
|
p:P2115
|
wd:statement/Q5984881-7D538649-F60B-4E72-8253-7425F89464F5
|
|
p:P2175
|
wd:statement/Q5984881-099588AD-AFF1-4280-983E-68BB8D2AF2CC
|
|
wd:statement/Q5984881-2B6C6368-BA96-4E47-87F2-A5297297EDAF
|
|
wd:statement/Q5984881-2EE59C93-1619-4CC4-A4A8-E26B25259AF5
|
|
wd:statement/Q5984881-3F5D12B4-F16D-41AB-87D0-BB87ADCDBA62
|
|
wd:statement/Q5984881-503E0BBD-5DBF-4757-B07B-EC76E6FE31C8
|
|
wd:statement/Q5984881-564A3486-E746-4A1B-B088-B755B5E0C3F3
|
|
wd:statement/Q5984881-7566D56C-12DF-402E-8211-59FA02D27899
|
|
wd:statement/Q5984881-99558E36-3221-491A-BC4A-3407968FFC0A
|
|
wd:statement/Q5984881-9FBB0590-87ED-424F-8A3A-794C506E3BD2
|
|
wd:statement/Q5984881-E60B2BF8-E4F3-4256-A741-6976C4391B80
|
|
wd:statement/Q5984881-FC0428A5-EC4C-4C02-B1AC-50A4B30EF8C0
|
|
p:P2275
|
wd:statement/Q5984881-262783C1-DB11-4A16-8D72-1E94541704C7
|
|
p:P231
|
wd:statement/Q5984881-AB269216-1648-4B16-91F8-FC6E7C59915B
|
|
p:P232
|
wd:statement/Q5984881-7B7060E0-E995-45AB-A2AE-AD81301AF77C
|
|
p:P233
|
wd:statement/Q5984881-95F1AFAB-D735-453E-A3D7-A9B02028D557
|
|
p:P234
|
wd:statement/Q5984881-3B78B8A7-C89A-4784-87CF-C3044ACEA1EF
|
|
p:P235
|
wd:statement/Q5984881-729D3DFD-311E-4F9F-94EE-ADE72C6DAFEA
|
|
p:P2566
|
wd:statement/Q5984881-13572468-2468-1357-eca9-bdf024681357
|
|
p:P267
|
wd:statement/Q5984881-87D5CB89-9D1C-47B9-A164-D9512F1E36E5
|
|
p:P274
|
wd:statement/Q5984881-0F3ACA8D-C0D1-452A-A629-FA3916504B51
|
|
p:P279
|
wd:statement/Q5984881-42526DF3-5A60-45D7-855E-2576F34B7FA0
|
|
p:P2868
|
wd:statement/Q5984881-A9611CEF-4BDC-4B1C-B4D4-1A0AD8C4D7F7
|
|
p:P2877
|
wd:statement/Q5984881-B62CBF5C-B012-461D-A3C4-F7C8F5BF5989
|
|
p:P2892
|
wd:statement/Q5984881-5F8CDEFF-B17A-44DA-8DB9-1CA147491BB6
|
|
p:P31
|
wd:statement/Q5984881-54E2C22E-E25A-434C-AFAF-0A799DFEAB26
|
|
p:P3117
|
wd:statement/Q5984881-6DB6338C-BE33-4FBE-B9A5-2884862D1527
|
|
p:P3345
|
wd:statement/Q5984881-3AC68C61-0DA3-4C1C-90A3-6688892449BB
|
|
p:P3489
|
wd:statement/Q5984881-845D0D6B-8451-47EA-B132-A41CCF4B8553
|
|
p:P3636
|
wd:statement/Q5984881-20139A6B-6FF2-46A1-86C5-130B3DAED413
|
|
p:P366
|
wd:statement/Q5984881-3D85B691-CE3F-4DC6-A8E6-5DFE7CDEF6E4
|
|
p:P373
|
wd:statement/Q5984881-77521995-0A8B-4EF4-A766-A7DB64E50F74
|
|
p:P3780
|
wd:statement/Q5984881-53489641-A532-4F55-8602-D3E406ACEFD9
|
|
p:P4527
|
wd:statement/Q5984881-97B5CB19-8A61-4218-9516-DF2F950665A6
|
|
p:P527
|
wd:statement/Q5984881-D7BD32BD-8FBD-4106-9A93-00F52D6E85B8
|
|
p:P592
|
wd:statement/Q5984881-6D91BB4F-A4A6-497A-8370-23BBABBE447B
|
|
p:P595
|
wd:statement/Q5984881-2DEC1A2F-FA91-472F-8648-6C01EE7F78AB
|
|
p:P6366
|
wd:statement/Q5984881-179CD9EB-C4B5-4B99-93DA-7C2C1CD5DD2F
|
|
p:P638
|
wd:statement/Q5984881-3BD17149-785C-440B-BD92-81D0F1852983
|
|
wd:statement/Q5984881-73771749-0F04-4A15-8430-AEFA9D349735
|
|
p:P646
|
wd:statement/Q5984881-F68A13A3-CFF0-4789-8431-EBAE9E891D04
|
|
p:P652
|
wd:statement/Q5984881-C4E247F7-E4BB-46CA-B8F4-CFD6FE4F12EA
|
|
p:P661
|
wd:statement/Q5984881-77EEDDA0-23BD-406E-8249-7E95B17388DC
|
|
p:P662
|
wd:statement/Q5984881-DED2210B-994A-4FE9-9BCC-7AE53A4F37B3
|
|
p:P665
|
wd:statement/Q5984881-6DA5A73B-2A90-4855-A302-8CBDC4F2D369
|
|
p:P683
|
wd:statement/Q5984881-BF0D336B-31CD-4E6E-953C-8B063D11F7BF
|
|
p:P715
|
wd:statement/Q5984881-C00A9644-411B-4740-B675-8B801BA3FD13
|
|
p:P769
|
wd:statement/Q5984881-05B38698-9F76-4F83-917F-5E1283F6EBC3
|
|
wd:statement/Q5984881-07BB5D75-3C5C-43CA-9573-C62F0A26DEEB
|
|
wd:statement/Q5984881-1A8EF67C-8A71-40ED-A1F1-5F83663C50B5
|
|
wd:statement/Q5984881-3685FD89-7F5F-4493-B508-5BF389415212
|
|
wd:statement/Q5984881-4ACC2F14-54D5-4AA6-A359-C585DA3E6135
|
|
wd:statement/Q5984881-56F747BC-3012-4987-86F9-07ED3A816604
|
|
wd:statement/Q5984881-7F189E99-5152-4370-9D48-8F995B8D8A83
|
|
wd:statement/Q5984881-90E09886-B9A4-4271-8084-93F23C796807
|
|
wd:statement/Q5984881-92352FC0-9E77-4ED7-8DE8-743DCDA77348
|
|
wd:statement/Q5984881-9F763557-AF11-4091-AB15-83D8B3BDCDFF
|
|
wd:statement/Q5984881-A35251E5-2761-4703-B907-DCDBFA9F3B2C
|
|
wd:statement/Q5984881-D78CBBCD-51E2-4F98-BEE8-FDCAF2868B6F
|
|
wd:statement/Q5984881-E16CD27D-61E6-4612-A7B2-7673FFBF506D
|
|
wd:statement/Q5984881-FFFB7B8E-0D09-431B-8948-79C8EB20F50A
|
|
p:P7830
|
wd:statement/Q5984881-4ACE03D9-BF17-42B8-8538-0F15B2743CC2
|
|
p:P8026
|
wd:statement/Q5984881-0EDA508B-9886-4157-81F6-B7AD7528170C
|
|
p:P8494
|
wd:statement/Q5984881-3BEFE2AC-8CDC-4402-A04E-24A7C4424645
|
|
p:direct-normalized/P2115
|
<http://purl.bioontology.org/ontology/NDFRT/N0000189502>
|
|
p:direct-normalized/P4527
|
<http://data.parliament.uk/terms/446352>
|
|
p:direct-normalized/P592
|
<http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL1873475>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/2779878957>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/4IFG>
|
|
<https://rdf.wwpdb.org/pdb/4RZ7>
|
|
p:direct-normalized/P661
|
<http://rdf.chemspider.com/26637187>
|
|
p:direct-normalized/P662
|
<http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24821094>
|
|
p:direct-normalized/P665
|
<http://www.kegg.jp/entry/D10223>
|
|
p:direct-normalized/P683
|
<http://purl.obolibrary.org/obo/CHEBI_76612>
|
|
wdt:P10245
|
"a614007"
|
|
wdt:P10283
|
"C2779878957"
|
|
wdt:P11089
|
"1110206"
|
|
wdt:P11143
|
"Ibrutinib"
|
|
wdt:P11198
|
"4810"
|
|
wdt:P11199
|
"PD003357"
|
|
wdt:P117
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PCI-32765.svg>
|
|
wdt:P129
|
BMX non-receptor tyrosine kinase
|
|
BLK proto-oncogene, Src family tyrosine kinase
|
|
Bruton's tyrosine kinase
|
|
wdt:P1579
|
"13102252"
|
|
wdt:P2017
|
"C=CC(=O)N1CCC[C@H](C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=NC=N3)N"
|
|
wdt:P2062
|
"8260"
|
|
wdt:P2067
|
440.196^^xsd:decimal
|
|
wdt:P2115
|
"N0000189502"
|
|
wdt:P2175
|
chronic lymphocytic leukemia
|
|
non-Hodgkin lymphoma
|
|
graft-versus-host disease
|
|
central nervous system lymphoma
|
|
Waldenström macroglobulinemia
|
|
lymphoblastic leukemia
|
|
lymphoma
|
|
diffuse large B-cell lymphoma
|
|
mantle cell lymphoma
|
|
leukemia
|
|
B-cell lymphoma
|
|
wdt:P2275
|
"ibrutinib"@en
|
|
wdt:P231
|
"936563-96-1"
|
|
wdt:P232
|
"805-642-2"
|
|
wdt:P233
|
"C=CC(=O)N1CCCC(C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=NC=N3)N"
|
|
wdt:P234
|
"InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m1/s1"
|
|
wdt:P235
|
"XYFPWWZEPKGCCK-GOSISDBHSA-N"
|
|
wdt:P2566
|
"100.232.543"
|
|
wdt:P267
|
"L01XE27"
|
|
wdt:P274
|
"C₂₅H₂₄N₆O₂"
|
|
wdt:P279
|
1-[3-[4-amino-3-(4-phenoxyphenyl)-1-pyrazolo[3,4-d]pyrimidinyl]-1-piperidinyl]-2-propen-1-one
|
|
wdt:P2868
|
protein kinase inhibitors
|
|
wdt:P2877
|
"201859"
|
|
wdt:P2892
|
"C3501358"
|
|
wdt:P31
|
type of chemical entity
|
|
wdt:P3117
|
"DTXSID60893450"
|
|
wdt:P3345
|
"1442981"
|
|
wdt:P3489
|
US pregnancy category D
|
|
wdt:P3636
|
"1E8"
|
|
wdt:P366
|
medication
|
|
wdt:P373
|
"Ibrutinib"
|
|
wdt:P3780
|
Imbruvica
|
|
wdt:P4527
|
"446352"
|
|
wdt:P527
|
carbon
|
|
wdt:P592
|
"CHEMBL1873475"
|
|
wdt:P595
|
"6912"
|
|
wdt:P6366
|
"2779878957"
|
|
wdt:P638
|
"4IFG"
|
|
"4RZ7"
|
|
wdt:P646
|
"/m/0hr5hzf"
|
|
wdt:P652
|
"1X70OSD4VX"
|
|
wdt:P661
|
"26637187"
|
|
wdt:P662
|
"24821094"
|
|
wdt:P665
|
"D10223"
|
|
wdt:P683
|
"76612"
|
|
wdt:P715
|
"DB09053"
|
|
wdt:P769
|
rac-warfarin
|
|
imatinib
|
|
aspirin
|
|
eptifibatide
|
|
acenocoumarol
|
|
abciximab
|
|
clopidogrel
|
|
apixaban
|
|
tirofiban
|
|
prasugrel
|
|
rivaroxaban
|
|
ticagrelor
|
|
crizotinib
|
|
idelalisib
|
|
wdt:P7830
|
"Ibrutinib"
|
|
wdt:P8026
|
LiverTox toxicity likelihood category D
|
|
wdt:P8494
|
"DTXCID601323465"
|
