SHMARQL

ivacaftor

<http://www.wikidata.org/entity/Q6095693>

pharmaceutical drug
rdfs:label
"ivacaftor"@en
skos:altLabel
"N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide"@en
"VX-770"@en
schema:description
"pharmaceutical drug"@en
schema:dateModified "2026-06-29T05:16:14+00:00"^^xsd:dateTime
schema:version 2511702298
wikibase:identifiers 32
wikibase:sitelinks 15
wikibase:statements 47
p:P10245 wd:statement/Q6095693-74beae5f-443b-1c05-fc56-e15c1b5bb6ae
p:P10283 wd:statement/Q6095693-EF5324D0-8CF2-41D6-8DAF-09D623812859
p:P11089 wd:statement/Q6095693-E3905093-1E4A-424F-A498-9ABA4842CD09
p:P11143 wd:statement/Q6095693-517BE9FE-EE2E-446B-9409-5A0AF9983BAE
p:P11198 wd:statement/Q6095693-69F88B47-87DB-4B57-95A3-7A9FFBDC2E24
p:P11199 wd:statement/Q6095693-EB124635-BD9F-4E74-9E1D-13F8FC2CD5EB
p:P117 wd:statement/Q6095693-57256f32-4315-7bb7-88df-59e6649680a8
p:P129 wd:statement/Q6095693-6F8E80AD-A207-44B0-BF83-8BB57BE285F2
p:P2057 wd:statement/Q6095693-232A8BCA-2DE3-4D83-93B5-5A5144BCD47B
p:P2067 wd:statement/Q6095693-7E41C2F9-3CD4-4936-B018-3999BD739783
p:P2115 wd:statement/Q6095693-CA7709EA-53ED-43B9-BA6C-94DFB065DA7C
p:P2175 wd:statement/Q6095693-4583720E-BD87-4E56-9C7C-E00F167B68B1
p:P231 wd:statement/Q6095693-85A9E561-8FA5-4584-923E-2ACDDBC0E153
p:P232 wd:statement/Q6095693-127388F4-7F2D-404B-AAB8-FFFEE5549B39
p:P233 wd:statement/Q6095693-E1AF7437-2CA0-4B9B-9145-CE215C262CF2
p:P234 wd:statement/Q6095693-78B45F88-C942-4839-99C6-26FE7D340EC9
p:P235 wd:statement/Q6095693-ABD4E7E0-C1BB-45C6-A20B-C1DB11CC45CD
p:P2566 wd:statement/Q6095693-98032A73-D70A-497A-AF94-72E769AAA9F4
p:P267 wd:statement/Q6095693-7AE3FD06-0734-4D9F-94EF-E1165C3DA4A9
p:P274 wd:statement/Q6095693-B9A57052-616F-4E8C-AC28-807BEBC66DC1
p:P279 wd:statement/Q6095693-D44483DF-E86C-4E1F-B3C8-90BD21BC3759
p:P2868 wd:statement/Q6095693-0B09A87F-D55C-4520-AACD-5E91E5679F67
wd:statement/Q6095693-72AD74A0-E4DC-4643-AC34-82CA19533AB5
p:P2877 wd:statement/Q6095693-49D3746E-FBD7-4D1B-9F24-C96781ADBBC5
p:P2892 wd:statement/Q6095693-5E5A8730-3021-4A4C-B3AF-2B926DE774FA
p:P31 wd:statement/Q6095693-DF6D59BA-B9E6-4445-98FA-D1DBE429AAA0
p:P3117 wd:statement/Q6095693-1EC3F83D-1595-460E-A81B-15FA2553427C
p:P3345 wd:statement/Q6095693-79B24EFB-37A8-4B1B-8031-8D5A398AF789
p:P3489 wd:statement/Q6095693-DDAFAAC9-AA60-4316-BEF1-B69E209725DD
p:P3636 wd:statement/Q6095693-30CD9617-A331-464D-9307-92FDDEC8DFE8
p:P366 wd:statement/Q6095693-8A815A41-0C6B-48F9-B53B-4FB127EEA949
p:P373 wd:statement/Q6095693-6e7e7cf4-e863-4f6d-af31-7a3f769fcd8d
p:P3780 wd:statement/Q6095693-813034B2-AA07-4579-9168-B5E8ABD949C7
p:P4250 wd:statement/Q6095693-99226AD1-C3D9-45D9-8EC7-F0081A2F1282
p:P486 wd:statement/Q6095693-6E13B04C-4A47-467F-80C6-C3261B30EFA7
p:P4964 wd:statement/Q6095693-7B67EAAE-DF2A-4ACF-8A91-06EA5B58190B
p:P592 wd:statement/Q6095693-4C1540AA-0FC8-40F3-BE92-B8DD614476C0
p:P595 wd:statement/Q6095693-3A122B55-BECA-4CFD-8BF7-049CC5018F12
p:P6366 wd:statement/Q6095693-3EA83EA4-367D-4DB5-B15A-57CB41463068
p:P646 wd:statement/Q6095693-7C135745-9419-4404-BFCF-C0C7A4DF4766
p:P652 wd:statement/Q6095693-B144FC10-A7E9-4A99-8D9E-BED0EDFE362A
p:P661 wd:statement/Q6095693-571F71FC-FBBF-4AFE-97BD-5426B05F6D2B
p:P662 wd:statement/Q6095693-9962C7B8-8F45-43BF-927F-9028B56CB5CD
p:P665 wd:statement/Q6095693-B3531BAC-4191-4392-B4C6-FC1B3B990F71
p:P683 wd:statement/Q6095693-BDAADB44-5EDA-4177-96F2-BA0071606480
p:P715 wd:statement/Q6095693-86C6A67A-2D8C-45C5-9721-189304E44D71
p:P8494 wd:statement/Q6095693-86D80F42-50BC-4AF3-A9FB-2E9E399E54EB
p:direct-normalized/P2115 <http://purl.bioontology.org/ontology/NDFRT/N0000185033>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/C545203>
p:direct-normalized/P592 <http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL2010601>
p:direct-normalized/P6366 <https://makg.org/entity/2776502428>
p:direct-normalized/P661 <http://rdf.chemspider.com/17347474>
p:direct-normalized/P662 <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16220172>
p:direct-normalized/P665 <http://www.kegg.jp/entry/D09916>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_66901>
wdt:P10245 "a612012"
wdt:P10283 "C2776502428"
wdt:P11089 "1076838"
wdt:P11143 "Ivacaftor"
wdt:P11198 "4228"
wdt:P11199 "PD009194"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Ivacaftor.svg>
wdt:P129 cystic fibrosis transmembrane conductance regulator
wdt:P2057 "HMDB0015705"
wdt:P2067 392.209993^^xsd:decimal
wdt:P2115 "N0000185033"
wdt:P2175 cystic fibrosis
wdt:P231 "873054-44-5"
wdt:P232 "800-027-5"
wdt:P233 "CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C"
wdt:P234 "InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)"
wdt:P235 "PURKAOJPTOLRMP-UHFFFAOYSA-N"
wdt:P2566 "100.226.211"
wdt:P267 "R07AX02"
wdt:P274 "C₂₄H₂₈N₂O₃"
wdt:P279 chemical compound
wdt:P2868 xenobiotic-transporting ATPase inhibitor
chloride channel agonist
wdt:P2877 "351373"
wdt:P2892 "C3264621"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID00236281"
wdt:P3345 "1243041"
wdt:P3489 US pregnancy category B
wdt:P3636 "VX7"
wdt:P366 medication
wdt:P373 "Ivacaftor"
wdt:P3780 Kalydeco
wdt:P4250 0.3^^xsd:decimal
wdt:P486 "C545203"
wdt:P4964 "splash10-0079-1809000000-c0147e018d786aee606b"
wdt:P592 "CHEMBL2010601"
wdt:P595 "4342"
wdt:P6366 "2776502428"
wdt:P646 "/m/0gg58cr"
wdt:P652 "1Y740ILL1Z"
wdt:P661 "17347474"
wdt:P662 "16220172"
wdt:P665 "D09916"
wdt:P683 "66901"
wdt:P715 "DB08820"
wdt:P8494 "DTXCID00158772"
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data from SPARQL profile: Wikidata