|
rdfs:label
|
"Cinasa Jano 1"@es
"Janus kinase 1"@en
"Janus kinaza 1"@sh
"Janusova kinaza 1"@sl
"Янускиназа 1"@ru
|
|
skos:altLabel
|
"JAK-1"@en
"JAK1"@en
"JAK1"@es
"tyrosine-protein kinase JAK1"@en
|
|
schema:description
|
"Protein in Homo sapiens"@de
"mammalian protein found in Homo sapiens"@en
"protein"@sv
"protein"@id
"proteinë"@sq
"proteína encontrada en Homo sapiens"@es
"proteïne in Janus kinase 1"@nl
"protèin"@ace
"protéine"@fr
"білок людини"@uk
"بروتين في الإنسان العاقل"@ar
|
|
schema:dateModified
|
"2026-07-23T15:35:58+00:00"^^xsd:dateTime
|
|
schema:version
|
2521706474
|
|
wikibase:identifiers
|
34
|
|
wikibase:sitelinks
|
0
|
|
wikibase:statements
|
126
|
|
p:P129
|
wd:statement/Q6155967-0DE33303-CC2E-4FAC-8EBB-7B81F0B232B1
|
|
wd:statement/Q6155967-1479BA93-1A7B-45E6-8098-4029721321D5
|
|
wd:statement/Q6155967-304CF87E-4D51-469A-931F-F6511D7A6DD4
|
|
wd:statement/Q6155967-3622312b-489d-1dfc-1f57-ce68a3a2717f
|
|
wd:statement/Q6155967-39D7672A-3661-4B86-8230-CE3ED633ECF1
|
|
wd:statement/Q6155967-4ED08ACD-9470-453D-90E9-016C44054508
|
|
wd:statement/Q6155967-71962027-9A75-4294-B4E9-B9F0C562F0D1
|
|
wd:statement/Q6155967-91A72A0F-E815-42D2-A5E9-39B55BC51C0D
|
|
wd:statement/Q6155967-E10D79A7-9C32-4894-8C92-D78442FC19E0
|
|
p:P2892
|
wd:statement/Q6155967-EA90B07F-9C3C-440E-8D7D-787F613998E5
|
|
p:P31
|
wd:statement/Q6155967-83F1F449-DFF3-4ED6-9FFF-3B8E2F748AEA
|
|
p:P352
|
wd:statement/Q6155967-90DF7B08-430D-41AB-9F61-F0D307345657
|
|
p:P361
|
wd:statement/Q6155967-0AC84FDF-AD0D-48F4-9144-A53B13752BEF
|
|
wd:statement/Q6155967-115173F1-C391-4C57-AAE8-5E904DF6E251
|
|
wd:statement/Q6155967-1703C7D2-A8BC-4587-BF2C-D1AE1EEBAB56
|
|
wd:statement/Q6155967-46CF5513-7E7C-484E-98E7-90463B1E3C30
|
|
wd:statement/Q6155967-6CEC0018-09AB-4832-B9DA-7C45795F0366
|
|
wd:statement/Q6155967-74F622E6-F019-46E7-ADFB-C4F5E0397D82
|
|
wd:statement/Q6155967-79B70589-EB9B-4B86-B40C-50321B57DF9A
|
|
wd:statement/Q6155967-8913F0E1-A833-4E05-8B47-5E9C25788721
|
|
wd:statement/Q6155967-ADC6E34A-7FCA-47EE-AF95-27E9F9270B53
|
|
wd:statement/Q6155967-CF93B3EB-7CA0-4F2A-9100-964F500CBE25
|
|
wd:statement/Q6155967-EC14BAD9-6760-4229-9C1B-DED932EF8DC8
|
|
wd:statement/Q6155967-F57A2348-182B-47B5-A8D8-142A3F4E3842
|
|
wd:statement/Q6155967-F91BBC5A-E640-4428-AD8D-2727B2A0D1F6
|
|
p:P486
|
wd:statement/Q6155967-6E3E9C86-5463-4344-8491-0535DB87E15D
|
|
p:P527
|
wd:statement/Q6155967-0AF79373-EF01-4382-BBB8-B1753A7911E4
|
|
wd:statement/Q6155967-0B1D9799-7ABA-4478-B210-CA143F4EA023
|
|
wd:statement/Q6155967-5974D9D7-F66A-44D8-964C-E9298D9A3D25
|
|
wd:statement/Q6155967-63DA3364-004C-473F-BEE5-9319BE7EEADF
|
|
wd:statement/Q6155967-78939B0E-061F-4A1A-AC72-96E1CA837321
|
|
wd:statement/Q6155967-93F48B35-CC4E-4A1F-AD84-29CCEC2C1548
|
|
wd:statement/Q6155967-B6D65F26-F47C-456D-9D9E-EE560554881C
|
|
wd:statement/Q6155967-BFEA07DB-72A5-45B9-ACC3-C2BA4E673ACC
|
|
wd:statement/Q6155967-C34DC9BA-CFE9-4959-9777-41FF5ECB2DC5
|
|
p:P591
|
wd:statement/Q6155967-A59EE1D5-B948-493F-A9D1-00E01CA02898
|
|
p:P637
|
wd:statement/Q6155967-04AC00D5-C032-44DE-BC77-412496FC2576
|
|
wd:statement/Q6155967-277B637E-1CE2-402D-BE24-234C30E87A27
|
|
wd:statement/Q6155967-32959146-4237-4AC1-A839-9341C61423A9
|
|
wd:statement/Q6155967-5324A4C1-7224-47EC-BD66-DC1770F7FB67
|
|
wd:statement/Q6155967-65DA0434-7BF4-44F2-8460-FF20D6FFEF28
|
|
wd:statement/Q6155967-C368C313-44FB-4AB9-B7C6-46F12E89F4D3
|
|
wd:statement/Q6155967-C883275D-C142-4F00-850F-9E3CBFD26F7C
|
|
wd:statement/Q6155967-D942E059-16D5-4B00-B298-7B17A53F6441
|
|
p:P638
|
wd:statement/Q6155967-0115586A-189F-4937-9F23-C359D685DAB8
|
|
wd:statement/Q6155967-0BD86945-427A-44D7-B9F6-05E6152D174D
|
|
wd:statement/Q6155967-116D0E7A-FA47-4A4A-B5EB-9991EEA2B338
|
|
wd:statement/Q6155967-37218EF4-6C0B-4ECE-A12B-20D096F4B095
|
|
wd:statement/Q6155967-3FF5A1B4-FCAF-4FC1-87AC-DB1CA43BFCCA
|
|
wd:statement/Q6155967-4FA88A53-68A6-4669-9D39-B9BDA543062E
|
|
wd:statement/Q6155967-54E1FB25-268E-43CE-AAED-ACAE03E0FB7B
|
|
wd:statement/Q6155967-7B5BA54F-3A0A-4C7E-95CA-20F6ECD33096
|
|
wd:statement/Q6155967-94EEE783-29CF-4E95-9E06-9BAC8DDB94FD
|
|
wd:statement/Q6155967-97951122-3198-4426-A7FA-2C94F66C7672
|
|
wd:statement/Q6155967-A7CA1354-0235-4B96-BA09-A664DC8D5F73
|
|
wd:statement/Q6155967-A9CCB672-F665-48A5-964C-EDE9C3C403C5
|
|
wd:statement/Q6155967-AEE30425-2286-4BCC-BC63-86B4B087794A
|
|
wd:statement/Q6155967-C869EF28-FD7B-4723-8E3B-18D870F45DBA
|
|
wd:statement/Q6155967-CF3D726D-8B82-409E-B58D-3C5129D4B409
|
|
wd:statement/Q6155967-D5E6FE52-D175-4D7A-9983-2002E7C2A15D
|
|
wd:statement/Q6155967-E8F399A2-4BDD-495D-955A-6B0BCE16DD86
|
|
wd:statement/Q6155967-EB138D67-5515-4CF4-AA75-E07751FA535F
|
|
wd:statement/Q6155967-F407DA41-4AF9-412F-AB6C-87C99F2624BD
|
|
wd:statement/Q6155967-F457EE9D-2D0E-45DF-BE0C-CEB5ED8B20C7
|
|
p:P672
|
wd:statement/Q6155967-e9ad2901-484c-8539-7070-cf7c592cafce
|
|
wd:statement/Q6155967-ea07c202-4ccb-70b1-2313-659fde3eb711
|
|
p:P680
|
wd:statement/Q6155967-119EF853-44BD-4D1F-92F5-D0DAC69DF4F0
|
|
wd:statement/Q6155967-2E6FE52A-2201-4E75-83ED-D7747006FAFC
|
|
wd:statement/Q6155967-33478B36-B79D-42C5-968A-6374905FF898
|
|
wd:statement/Q6155967-3B99A00F-EC27-4735-AED3-5DBF0D347282
|
|
wd:statement/Q6155967-4238499E-CF73-4491-A0F4-CA27A3B57BC8
|
|
wd:statement/Q6155967-5B54F089-C8D9-44A8-A7FC-E9C750280F63
|
|
wd:statement/Q6155967-60AB185E-E4D7-486B-BD3F-FEC6D3FA296D
|
|
wd:statement/Q6155967-81DB5809-1FC0-4009-B1D8-C78253CC08FC
|
|
wd:statement/Q6155967-823E5CDE-41AA-4C23-A273-D82F98295A78
|
|
wd:statement/Q6155967-9640FD34-2FC7-4CD5-AF50-082CB3D869CC
|
|
wd:statement/Q6155967-AC85C7A1-261D-4940-926F-CD7C587183CC
|
|
wd:statement/Q6155967-AEF3A60C-4FD4-4C4E-A2B8-63ACE08A31B4
|
|
wd:statement/Q6155967-CB9CFFE7-B321-4E91-B505-8E4F6E7D3C88
|
|
wd:statement/Q6155967-D04E452D-1D61-4A9A-B3D1-5159BC7D2B29
|
|
wd:statement/Q6155967-D9EE65F3-B763-4F35-9AA5-6E50C4A7C112
|
|
wd:statement/Q6155967-F2AB1E4F-ACB9-4F8E-98F8-660DDF8DA368
|
|
p:P681
|
wd:statement/Q6155967-0E6AB027-7E1A-4F39-AE60-C8572A1D6A45
|
|
wd:statement/Q6155967-1D37D43F-C1B2-42E2-8E09-29A5815E9164
|
|
wd:statement/Q6155967-25FC32AE-F3F7-49C2-B6D0-75291BCBB9E6
|
|
wd:statement/Q6155967-477B0F71-3731-497E-859C-61AE63B7D3CF
|
|
wd:statement/Q6155967-58EBA9C3-9155-404F-A2A5-5716669CCD1D
|
|
wd:statement/Q6155967-628DF9B6-0C1A-4CE9-B163-4E791460DE1A
|
|
wd:statement/Q6155967-6E036192-A090-4811-BEC9-AE9D37816315
|
|
wd:statement/Q6155967-7ADAB92E-D716-46A9-8B3B-79AC9EE96EA8
|
|
wd:statement/Q6155967-82908ED4-BED4-4840-BA69-B53074C029CE
|
|
wd:statement/Q6155967-FD8CC7CD-F028-4928-B5F4-A3406D2AFA7F
|
|
p:P682
|
wd:statement/Q6155967-01DAA33B-E988-4353-9DB8-755A5441178A
|
|
wd:statement/Q6155967-03B68DBF-0B5A-4E32-8619-36627A8374DC
|
|
wd:statement/Q6155967-1125B8CD-76A6-4C5D-B444-B8BF22B17948
|
|
wd:statement/Q6155967-15A59007-B2F6-4388-9F28-CEA3495E04C5
|
|
wd:statement/Q6155967-165C5857-9257-4AE3-839D-15BD645BC114
|
|
wd:statement/Q6155967-1775E8E5-37F7-483D-A904-F7E9348DC661
|
|
wd:statement/Q6155967-1ABE3977-9AA3-4A42-AAA9-F431EDFD56A3
|
|
wd:statement/Q6155967-1AEAC95A-454B-4C41-8CD9-017ABD430C58
|
|
wd:statement/Q6155967-2091F9DD-766F-41C9-B37B-7806C1CDA698
|
|
wd:statement/Q6155967-25C6BFCD-7DA6-4897-AB1E-D796EEC73F76
|
|
wd:statement/Q6155967-2C4D3182-8E5F-40C3-92F9-32C7D709872E
|
|
wd:statement/Q6155967-2D344883-ED55-4B89-B136-CAAC8E59639E
|
|
wd:statement/Q6155967-328A66CB-9223-44E4-B703-FB494465EA4B
|
|
wd:statement/Q6155967-35A1FE3D-43AE-4E64-A9BE-C47D2FA853F6
|
|
wd:statement/Q6155967-3AC74A5C-A2E5-4CB0-A2B0-978B835BF1F9
|
|
wd:statement/Q6155967-48E32C40-3B98-4FEE-A87A-4FCFC45F2338
|
|
wd:statement/Q6155967-4C746C38-1518-4B5E-AFE4-09883DCC4666
|
|
wd:statement/Q6155967-542AAD0B-2BE3-476A-9B33-D01483968372
|
|
wd:statement/Q6155967-5611B217-8B42-44B6-982C-67E17936719F
|
|
wd:statement/Q6155967-81E171C1-FDA5-4FD6-A7CD-4649A22E2201
|
|
wd:statement/Q6155967-83DD83BB-6162-4445-B7F2-EB5BD0B78D7D
|
|
wd:statement/Q6155967-ACCFE856-CE55-4333-8531-3639BAC9B28A
|
|
wd:statement/Q6155967-B1E2A8B9-C1A2-4637-A5F0-3C790FAC559A
|
|
wd:statement/Q6155967-C99DA9AC-3447-4700-8F02-5AE228DBDBB0
|
|
wd:statement/Q6155967-DCBBFBBB-6B5F-4789-93FD-3485D195A039
|
|
wd:statement/Q6155967-E3B5625E-D9C2-45DD-AC20-8FC4BE88BB7F
|
|
wd:statement/Q6155967-E7BF8D3C-059E-478D-BB95-6E147C66D186
|
|
wd:statement/Q6155967-EAB63A82-E3A9-4D50-9591-4E9A0F496982
|
|
wd:statement/Q6155967-F24CFA6D-333B-439C-8085-A0C67E41243C
|
|
wd:statement/Q6155967-FBD7A105-7C6D-4F32-9F2E-6BA86CECA284
|
|
p:P692
|
wd:statement/Q6155967-04D37BCB-2DDE-4B71-8897-CB1427E4248A
|
|
p:P702
|
wd:statement/Q6155967-D66BC17E-627B-448F-8287-27CFE946B9DA
|
|
p:P703
|
wd:statement/Q6155967-F706C80B-72BD-4FAB-B082-3AAF0A2952BA
|
|
p:P705
|
wd:statement/Q6155967-F22480D6-DE34-44D1-845E-FB8AD48C21C4
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P23458>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/D053613>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_001307852>
|
|
<http://purl.uniprot.org/refseq/NP_001308781>
|
|
<http://purl.uniprot.org/refseq/NP_001308782>
|
|
<http://purl.uniprot.org/refseq/NP_001308783>
|
|
<http://purl.uniprot.org/refseq/NP_001308784>
|
|
<http://purl.uniprot.org/refseq/NP_001308785>
|
|
<http://purl.uniprot.org/refseq/NP_001308786>
|
|
<http://purl.uniprot.org/refseq/NP_002218>
|
|
p:direct-normalized/P638
|
<https://rdf.wwpdb.org/pdb/3EYG>
|
|
<https://rdf.wwpdb.org/pdb/3EYH>
|
|
<https://rdf.wwpdb.org/pdb/4E4L>
|
|
<https://rdf.wwpdb.org/pdb/4E4N>
|
|
<https://rdf.wwpdb.org/pdb/4E5W>
|
|
<https://rdf.wwpdb.org/pdb/4EHZ>
|
|
<https://rdf.wwpdb.org/pdb/4EI4>
|
|
<https://rdf.wwpdb.org/pdb/4FK6>
|
|
<https://rdf.wwpdb.org/pdb/4I5C>
|
|
<https://rdf.wwpdb.org/pdb/4IVB>
|
|
<https://rdf.wwpdb.org/pdb/4IVC>
|
|
<https://rdf.wwpdb.org/pdb/4IVD>
|
|
<https://rdf.wwpdb.org/pdb/4K6Z>
|
|
<https://rdf.wwpdb.org/pdb/4K77>
|
|
<https://rdf.wwpdb.org/pdb/4L00>
|
|
<https://rdf.wwpdb.org/pdb/4L01>
|
|
<https://rdf.wwpdb.org/pdb/5E1E>
|
|
<https://rdf.wwpdb.org/pdb/5HX8>
|
|
<https://rdf.wwpdb.org/pdb/5IXD>
|
|
<https://rdf.wwpdb.org/pdb/5IXI>
|
|
p:direct-normalized/P672
|
<http://id.nlm.nih.gov/mesh/D08.811.913.696.620.682.725.124.100>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.476.568.124.100>
|
|
wdt:P129
|
filgotinib
|
|
momelotinib
|
|
upadacitinib
|
|
peficitinib
|
|
pacritinib
|
|
baricitinib
|
|
ruxolitinib
|
|
wdt:P2892
|
"C0169658"
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P23458"
|
|
wdt:P361
|
Protein kinase-like domain superfamily
|
|
tyrosine-protein kinase, non-receptor Jak1
|
|
FERM superfamily, second domain
|
|
SH2 domain superfamily
|
|
Tyrosine-protein kinase, catalytic domain, protein family
|
|
FERM central domain, protein family
|
|
FERM domain, protein family
|
|
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
|
|
Protein kinase domain, protein family
|
|
SH2 domain, protein family
|
|
Band 4.1 domain, protein family
|
|
Tyrosine-protein kinase, active site, protein family
|
|
Protein kinase, ATP binding site, protein family
|
|
wdt:P486
|
"D053613"
|
|
wdt:P527
|
tyrosine-protein kinase, catalytic domain
|
|
FERM central domain
|
|
FERM domain
|
|
tyrosine-protein kinase, active site
|
|
serine-threonine/tyrosine-protein kinase, catalytic domain
|
|
protein kinase domain
|
|
protein kinase, ATP binding site
|
|
SH2 domain
|
|
Band 4.1 domain
|
|
wdt:P591
|
"2.7.10.2"
|
|
wdt:P637
|
"NP_001307852"
|
|
"NP_001308781"
|
|
"NP_001308782"
|
|
"NP_001308783"
|
|
"NP_001308784"
|
|
"NP_001308785"
|
|
"NP_001308786"
|
|
"NP_002218"
|
|
wdt:P638
|
"3EYG"
|
|
"3EYH"
|
|
"4E4L"
|
|
"4E4N"
|
|
"4E5W"
|
|
"4EHZ"
|
|
"4EI4"
|
|
"4FK6"
|
|
"4I5C"
|
|
"4IVB"
|
|
"4IVC"
|
|
"4IVD"
|
|
"4K6Z"
|
|
"4K77"
|
|
"4L00"
|
|
"4L01"
|
|
"5E1E"
|
|
"5HX8"
|
|
"5IXD"
|
|
"5IXI"
|
|
wdt:P672
|
"D08.811.913.696.620.682.725.124.100"
|
|
"D12.776.476.568.124.100"
|
|
wdt:P680
|
metal ion binding
|
|
ubiquitin protein ligase binding
|
|
ATP binding
|
|
signaling receptor binding
|
|
protein kinase activity
|
|
transferase activity
|
|
nucleotide binding
|
|
protein phosphatase binding
|
|
kinase activity
|
|
protein tyrosine kinase activity
|
|
non-membrane spanning protein tyrosine kinase activity
|
|
CCR5 chemokine receptor binding
|
|
growth hormone receptor binding
|
|
protein binding
|
|
wdt:P681
|
membrane
|
|
extrinsic component of cytoplasmic side of plasma membrane
|
|
cytoskeleton
|
|
cytosol
|
|
nucleus
|
|
cytoplasm
|
|
endosome
|
|
endomembrane system
|
|
focal adhesion
|
|
wdt:P682
|
peptidyl-tyrosine phosphorylation
|
|
MAPK cascade
|
|
response to antibiotic
|
|
regulation of cell population proliferation
|
|
intracellular signal transduction
|
|
cytokine-mediated signaling pathway
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
|
type I interferon signaling pathway
|
|
interleukin-6-mediated signaling pathway
|
|
interferon-gamma-mediated signaling pathway
|
|
interleukin-2-mediated signaling pathway
|
|
interleukin-7-mediated signaling pathway
|
|
regulation of interferon-gamma-mediated signaling pathway
|
|
regulation of type I interferon-mediated signaling pathway
|
|
interleukin-27-mediated signaling pathway
|
|
interleukin-12-mediated signaling pathway
|
|
peptidyl-tyrosine autophosphorylation
|
|
cell migration
|
|
cell differentiation
|
|
interleukin-15-mediated signaling pathway
|
|
interleukin-21-mediated signaling pathway
|
|
positive regulation of sprouting angiogenesis
|
|
interleukin-9-mediated signaling pathway
|
|
interleukin-35-mediated signaling pathway
|
|
regulation of molecular function
|
|
phosphorylation
|
|
protein autophosphorylation
|
|
innate immune response
|
|
protein phosphorylation
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20JAK1%20201648%20at%20fs.png>
|
|
wdt:P702
|
JAK1
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000343204"
|
