SHMARQL

simvastatin

<http://www.wikidata.org/entity/Q670131>

lipid-lowering medication
rdfs:label
"simvastatin"@en
skos:altLabel
"(+)-Simvastatin"@en
"(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate"@en
"2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one"@en
"2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one"@en
"Cholestat"@en
"Denan"@en
"Eucor"@en
"Kolestevan"@en
"Lipex"@en
"Lipinorm"@en
"Liponorm"@en
"Lipovas"@en
"Lodales"@en
"MK-733"@en
"Modutrol"@en
"Nor-Vastina"@en
"Rechol"@en
"SIV691"@en
"Simcor"@en
"Simovil"@en
"Simvastatin"@en
"Simvastatin lactone"@en
"Simvastatina"@en
"Simvastatine"@en
"Simvastatinum"@en
"Simvotin"@en
"Sinvacor"@en
"Sinvascor"@en
"Sivastin"@en
"Synvinolin"@en
"Valemia"@en
"Velostatin"@en
"Zocor"@en
"Zocord"@en
"Zocor®"@en
schema:description
"lipid-lowering medication"@en
schema:dateModified "2026-04-05T12:51:38+00:00"^^xsd:dateTime
schema:version 2478540161
wikibase:identifiers 71
wikibase:sitelinks 39
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wdt:P10245 "a692030"
wdt:P10283 "C2776329913"
wdt:P11089 "21972"
wdt:P11143 "Simvastatin"
wdt:P11198 "2445"
wdt:P11199 "PD001216"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Simvastatin%20Structural%20Formulae.svg>
wdt:P129 3-hydroxy-3-methylglutaryl-CoA reductase
wdt:P13204 "e2278hh7"
wdt:P1579 "4768037"
wdt:P2017 "CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C"
wdt:P2057 "HMDB0005007"
wdt:P2062 "7208"
wdt:P2067 418.272^^xsd:decimal
wdt:P2115 "N0000148200"
wdt:P2175 hypertriglyceridemia
lipedema
arteriosclerosis
familial hyperlipidemia
coronary artery disease
wdt:P2275 "simvastatin"@en
wdt:P231 "79902-63-9"
wdt:P232 "616-751-8"
wdt:P233 "CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C"
wdt:P234 "InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1"
wdt:P235 "RYMZZMVNJRMUDD-HGQWONQESA-N"
wdt:P2566 "100.115.749"
wdt:P267 "C10AA01"
wdt:P274 "C₂₅H₃₈O₅"
wdt:P279 statin
wdt:P2840 "758706"
wdt:P2868 WHO essential medicines
anticholesteremic agents
statin
hypolipidemic
wdt:P2877 "2471"
wdt:P2892 "C0074554"
"C0733683"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID0023581"
wdt:P3345 "36567"
wdt:P3350 "6147"
wdt:P3364 [(1S,3R,7S,8R,8aS)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
wdt:P3489 US pregnancy category X
Australian pregnancy category D
wdt:P3493 boxed warning
wdt:P361 response to simvastatin
wdt:P366 medication
wdt:P373 "Simvastatin"
wdt:P3780 Flolipid
Zocor
wdt:P4235 "simvastatin"
wdt:P4250 30.0^^xsd:decimal
wdt:P486 "D019821"
wdt:P4964 "splash10-0006-0000900000-7f9cb5f83c393a4262cb"
"splash10-000e-0590000000-7f99e0b9531d4f42831a"
"splash10-002f-2900000000-abe04d7f99c3eb0f2fcb"
"splash10-006w-0790000000-4f23e0376d85845e0964"
"splash10-0092-0910000000-6ecd838b2f6fddf67dad"
"splash10-0092-1960000000-e8429bbec985c5ecdd2d"
"splash10-010a-0980000000-65c631834486c03b85a7"
"splash10-0536-1900000000-d8a41a97ccbdb30e5a5e"
"splash10-0592-1910000000-dc09a51ca37fe4d24a5a"
"splash10-0597-0900000000-012d0d6fcabbd21d696d"
"splash10-05i1-0940000000-058f6298af54c05532ed"
"splash10-0a4i-3900000000-d04758924bf88a90c017"
"splash10-0abd-1900000000-9b55821f49270e5dd598"
wdt:P5063 "i58957"
wdt:P527 carbon
oxygen
wdt:P592 "CHEMBL1064"
wdt:P595 "2955"
wdt:P6366 "2776329913"
wdt:P646 "/m/02z428"
wdt:P652 "AGG2FN16EV"
wdt:P661 "49179"
wdt:P662 "54454"
wdt:P665 "D00434"
wdt:P6689 "MSBNK-Athens_Univ-AU112801"
"MSBNK-Athens_Univ-AU112802"
"MSBNK-Athens_Univ-AU112803"
"MSBNK-Athens_Univ-AU112804"
"MSBNK-Athens_Univ-AU112805"
"MSBNK-Eawag-EQ314401"
"MSBNK-Eawag-EQ314402"
"MSBNK-Eawag-EQ314403"
"MSBNK-Eawag-EQ314404"
"MSBNK-Eawag-EQ314405"
"MSBNK-Eawag-EQ314406"
wdt:P672 "D02.455.426.559.847.638.400.900"
"D04.615.638.400.900"
wdt:P683 "9150"
wdt:P703 Neosartorya udagawae
Aspergillus udagawae
wdt:P715 "DB00641"
wdt:P7524 "simvastatin"
wdt:P769 clarithromycin
erythromycin
telithromycin
(S)-(−)-colchicine
ciprofibrate
cyclosporine
darunavir
gemfibrozil
ketoconazole
amiodarone
verapamil
carbamazepin
itraconazole
amlodipine
fluconazole
eltrombopag
nefazodone
(2R)-daptomycin
danazol
fenofibrate
amprenavir
diltiazem
lopinavir
ritonavir
saquinavir
nelfinavir
tipranavir
atazanavir
cobicistat
bezafibrate
idelalisib
posaconazole
ranolazine
wdt:P7830 "Simvastatin"
wdt:P8026 LiverTox toxicity likelihood category A
wdt:P8072 "268964"
wdt:P8494 "DTXCID103581"
wdt:P8814 "04229061-n"
wdt:P9272 "33420"
wdt:P9405 "20168321"
wdt:P9635 "148"
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