|
rdfs:label
|
"11-бета-гидроксилаза"@ru
"11β-水酸化酵素"@ja
"CYP11B1"@uk
"CYP11B1"@bs
"Cytochrome P450 family 11 subfamily B member 1"@nl
"Steroid-11beta-Hydroxylase"@de
"cytochrome P450 family 11 subfamily B member 1"@en
"类固醇11-β-羟化酶"@zh
|
|
skos:altLabel
|
"1.14.15.4"@en
"11-beta-Hydroxylase"@de
"11-β-ヒドロキシラーゼ"@ja
"CYP11B1"@de
"CYP11B1"@en
"CYP11B1"@ru
"CYP11B2"@de
"CYPXIB1"@en
"cytochrome P-450c11"@en
"cytochrome P450 11B1, mitochondrial"@en
"cytochrome P450, family 11, subfamily B, polypeptide 1"@en
"cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1"@en
"cytochrome P450C11"@en
"cytochrome p450 XIB1"@en
"steroid 11-beta-hydroxylase"@en
"steroid 11-beta-hydroxylase, CYP11B1"@en
"steroid 11-beta-monooxygenase"@en
"甾体11-β-羟化酶"@zh
|
|
schema:description
|
"Protein"@de
"mammalian protein found in Homo sapiens"@en
"menselijk eiwit"@nl
"protein"@sv
"protein"@id
"proteinë"@sq
"protèin"@ace
"protéine humaine"@fr
"білок людини"@uk
"фермент человека"@ru
"بروتين في الإنسان العاقل"@ar
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|
schema:dateModified
|
"2025-07-23T18:28:27+00:00"^^xsd:dateTime
|
|
schema:version
|
2383215757
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|
wikibase:identifiers
|
18
|
|
wikibase:sitelinks
|
5
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|
wikibase:statements
|
66
|
|
p:P10283
|
wd:statement/Q904925-7243E315-9A39-4AB0-9BFD-0E0E4C8C7210
|
|
p:P129
|
wd:statement/Q904925-4C21570E-FAA1-4FC8-B350-305C55C19AB8
|
|
wd:statement/Q904925-8351CE41-2A51-4C97-85CD-3E3995B0E111
|
|
wd:statement/Q904925-B844BF50-5F60-4302-88EB-CFFED91B69D5
|
|
wd:statement/Q904925-C75CACA9-7B3B-42DD-81FD-2FEC0DDDFB4F
|
|
p:P1889
|
wd:statement/Q904925-06D50EE3-D53A-462D-9774-B6C53A1EECED
|
|
p:P2892
|
wd:statement/Q904925-23940BA9-CDC4-4426-B7A1-21FC29004390
|
|
p:P31
|
wd:statement/Q904925-52F05421-49ED-4149-8363-F0D72EECDDA5
|
|
p:P352
|
wd:statement/Q904925-7FD8FA08-EA92-4649-82C2-F9A24C005DF4
|
|
p:P361
|
wd:statement/Q904925-0946D423-97F9-4E31-B92C-84DFC4BD0389
|
|
wd:statement/Q904925-4E6AD08A-21D0-4345-8FE3-8D9ABD59AA66
|
|
wd:statement/Q904925-EDB7FC05-643C-4DDF-A835-BD285F08C8AC
|
|
p:P486
|
wd:statement/Q904925-DB564EF9-9DCE-47E9-A122-FCB52B41A91E
|
|
p:P527
|
wd:statement/Q904925-6A3396FF-F552-487E-8156-E5E5256BEC69
|
|
p:P591
|
wd:statement/Q904925-C5722F03-F4C6-42ED-B130-9AF3FA86C4FA
|
|
p:P6366
|
wd:statement/Q904925-DDFE49F1-F9CD-48B8-8FD4-AD5B206E16EE
|
|
p:P637
|
wd:statement/Q904925-1E7C4B7D-9D2C-4666-9347-4BA2852AB7A7
|
|
wd:statement/Q904925-702D4F2A-5595-4513-91A5-9E39D8C67AF3
|
|
p:P646
|
wd:statement/Q904925-0EF88687-5EFE-4F3B-B939-91D3F4775056
|
|
p:P672
|
wd:statement/Q904925-04b4287c-4541-3e63-0a39-9fe82fe0a46e
|
|
wd:statement/Q904925-37d457d6-4d53-ab29-f980-0b7d00ef9e38
|
|
wd:statement/Q904925-aedb6572-48a4-6268-0d11-14b19a63a683
|
|
wd:statement/Q904925-b10cbfa4-4b81-4ba9-48bc-d2e2027cde81
|
|
wd:statement/Q904925-c003d9a9-4aa0-79d1-2800-717c85d633f4
|
|
wd:statement/Q904925-c09047f0-4b7e-ce19-d57d-00ef090dadd4
|
|
p:P680
|
wd:statement/Q904925-0A621AAD-51C4-4918-B726-0650F77D9146
|
|
wd:statement/Q904925-23F5E93E-8749-4421-AB5A-F876B12FCB0F
|
|
wd:statement/Q904925-3C5C0405-86B2-4711-A408-8D2B6BB2979A
|
|
wd:statement/Q904925-42A78ECF-97F2-46EC-9D74-88C24D56364E
|
|
wd:statement/Q904925-45E38F56-E0B3-4373-88ED-83C1AA793082
|
|
wd:statement/Q904925-62860112-54E0-4F9D-B5B1-E177F195CE82
|
|
wd:statement/Q904925-94247003-265A-4FA2-91AD-84970BCC6272
|
|
wd:statement/Q904925-955D9F04-ED80-4323-BFFA-A16DE7F96896
|
|
wd:statement/Q904925-A01BCDAB-4610-41C0-8EAD-0C0A8D2D4C34
|
|
wd:statement/Q904925-ED9F26B1-74C0-40E7-91A4-50AB722D6DC8
|
|
p:P681
|
wd:statement/Q904925-1CC03862-379F-4918-9E0A-53622F985DC9
|
|
wd:statement/Q904925-68826470-0774-4CF8-B3AA-C9CD00ED999B
|
|
wd:statement/Q904925-8095D370-1CD4-4381-947A-FB89A67456EE
|
|
wd:statement/Q904925-E6CA9D21-8DA4-4576-B32C-9260E7BE4AB0
|
|
wd:statement/Q904925-F4DC0BFB-EFA3-4409-888C-9BD71984ADAB
|
|
p:P682
|
wd:statement/Q904925-130AE4A9-356A-46C1-843D-FF5DFBF55215
|
|
wd:statement/Q904925-2623C80B-D604-4DC4-8B19-EEEE8A698256
|
|
wd:statement/Q904925-32DE89C4-85C9-4B78-88CC-6F2A4827C3CF
|
|
wd:statement/Q904925-5C4CD574-38F3-4816-91F1-0307049F1B6D
|
|
wd:statement/Q904925-5FE774B9-47ED-41F7-B074-0B947D8AB44B
|
|
wd:statement/Q904925-62A33786-FE61-4170-BD0B-1F2D9AF095C8
|
|
wd:statement/Q904925-701D6DAD-5A26-4C12-9E63-ADADC53EA42A
|
|
wd:statement/Q904925-7912959E-25A1-4D10-9273-CFF7B9D51609
|
|
wd:statement/Q904925-7B503D6E-D4FF-42CB-9565-9845D4E2BFDE
|
|
wd:statement/Q904925-8A0737D8-5CE1-4895-A672-BB520F07288E
|
|
wd:statement/Q904925-8D6D2F57-E91E-4021-B2CE-EE65DE9BE2AE
|
|
wd:statement/Q904925-945411D9-4C8F-4272-B649-B26F5A00DA5A
|
|
wd:statement/Q904925-95512B00-B30F-4FAE-B3A3-3C59722D12C2
|
|
wd:statement/Q904925-9E0B8D91-3F73-4CE9-92FA-4A333E6D075F
|
|
wd:statement/Q904925-BED8274C-0F63-4FF0-8DCB-D36A6912B263
|
|
wd:statement/Q904925-C69E7E6E-0569-4086-BD38-4ED31BE8EEBA
|
|
wd:statement/Q904925-D0E2D7A2-BE7E-4997-90EE-A04874AA2632
|
|
wd:statement/Q904925-DAF7B8F1-738A-45CD-9305-BC7205506280
|
|
wd:statement/Q904925-E8049D48-2DF1-4D82-98A6-F6C3ECB829B4
|
|
p:P692
|
wd:statement/Q904925-C7E4A215-9490-4948-8A44-D4D28FB9F18D
|
|
p:P702
|
wd:statement/Q904925-21969F2F-B9B8-4545-AA83-E17667D34C38
|
|
p:P703
|
wd:statement/Q904925-9791241E-E869-47ED-9539-B66F9A0CFA5B
|
|
p:P705
|
wd:statement/Q904925-36B31FF3-2234-4C4D-AE41-F339EE5C2ADD
|
|
wd:statement/Q904925-4E116920-CF7B-4B21-A84A-6FD49C4A2312
|
|
wd:statement/Q904925-A7F01F30-CF6D-41C8-BEDD-74917FB1377F
|
|
wd:statement/Q904925-C856A69A-2B39-4D2F-A168-2D26CF43DA77
|
|
p:direct-normalized/P352
|
<http://purl.uniprot.org/uniprot/P15538>
|
|
p:direct-normalized/P486
|
<http://id.nlm.nih.gov/mesh/D013252>
|
|
p:direct-normalized/P6366
|
<https://makg.org/entity/155392382>
|
|
p:direct-normalized/P637
|
<http://purl.uniprot.org/refseq/NP_000488>
|
|
<http://purl.uniprot.org/refseq/NP_001021384>
|
|
p:direct-normalized/P672
|
<http://id.nlm.nih.gov/mesh/D08.244.453.484.750>
|
|
<http://id.nlm.nih.gov/mesh/D08.244.453.915.750>
|
|
<http://id.nlm.nih.gov/mesh/D08.811.682.690.708.170.425.750>
|
|
<http://id.nlm.nih.gov/mesh/D08.811.682.690.708.170.915.750>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.422.220.453.484.750>
|
|
<http://id.nlm.nih.gov/mesh/D12.776.422.220.453.915.750>
|
|
wdt:P10283
|
"C155392382"
|
|
wdt:P129
|
osilodrostat
|
|
(RS)-mitotane
|
|
fadrozole
|
|
metyrapone
|
|
wdt:P1889
|
11-beta-hydroxysteroid dehydrogenase 1
|
|
wdt:P2892
|
"C0038296"
|
|
wdt:P31
|
protein
|
|
wdt:P352
|
"P15538"
|
|
wdt:P361
|
cytochrome P450, mitochondrial
|
|
cytochrome P450 superfamily
|
|
cytochrome P450, conserved site, protein family
|
|
wdt:P486
|
"D013252"
|
|
wdt:P527
|
cytochrome P450, conserved site
|
|
wdt:P591
|
"1.14.15.4"
|
|
wdt:P6366
|
"155392382"
|
|
wdt:P637
|
"NP_000488"
|
|
"NP_001021384"
|
|
wdt:P646
|
"/m/02pfxqv"
|
|
wdt:P672
|
"D08.244.453.484.750"
|
|
"D08.244.453.915.750"
|
|
"D08.811.682.690.708.170.425.750"
|
|
"D08.811.682.690.708.170.915.750"
|
|
"D12.776.422.220.453.484.750"
|
|
"D12.776.422.220.453.915.750"
|
|
wdt:P680
|
metal ion binding
|
|
oxidoreductase activity
|
|
iron ion binding
|
|
heme binding
|
|
monooxygenase activity
|
|
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
|
steroid 11-beta-monooxygenase activity
|
|
corticosterone 18-monooxygenase activity
|
|
wdt:P681
|
mitochondrial inner membrane
|
|
membrane
|
|
mitochondrial membranes
|
|
mitochondrion
|
|
wdt:P682
|
glucocorticoid biosynthetic process
|
|
steroid metabolic process
|
|
steroid biosynthetic process
|
|
C21-steroid hormone biosynthetic process
|
|
cholesterol metabolic process
|
|
sterol metabolic process
|
|
glucose homeostasis
|
|
regulation of blood pressure
|
|
cellular response to hormone stimulus
|
|
aldosterone biosynthetic process
|
|
cortisol biosynthetic process
|
|
cellular response to potassium ion
|
|
cellular response to peptide hormone stimulus
|
|
immune response
|
|
cortisol metabolic process
|
|
lipid metabolism
|
|
wdt:P692
|
<http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20CYP11B1%20214610%20at%20fs.png>
|
|
wdt:P702
|
CYP11B1
|
|
wdt:P703
|
man
|
|
wdt:P705
|
"ENSP00000292427"
|
|
"ENSP00000366903"
|
|
"ENSP00000428043"
|
|
"ENSP00000430144"
|
