SHMARQL

leuprolide

<http://www.wikidata.org/entity/Q907160>

chemical compound
rdfs:label
"leuprolide"@en
skos:altLabel
"(D-Leu(6),des-Gly-NH2(10),Pro-ethylamide(9))-gonadotropin-releasing hormone"@en
"ABBOTT-43818"@en
"L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide"@en
"Leuprorelin"@en
"Lupron®"@en
"TAP-144"@en
"pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHC2H5"@en
"pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt"@en
schema:description
"chemical compound"@en
schema:dateModified "2026-09-10T07:19:59+00:00"^^xsd:dateTime
schema:version 2543122195
wikibase:identifiers 41
wikibase:sitelinks 25
wikibase:statements 70
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p:P7830 wd:statement/Q907160-062F2D8A-237B-46B0-A207-2A22DF035AC4
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p:P8494 wd:statement/Q907160-9F3D8860-E881-4B1D-8FC8-DFD3DD5E3B4F
p:direct-normalized/P2115 <http://purl.bioontology.org/ontology/NDFRT/N0000147889>
p:direct-normalized/P4527 <http://data.parliament.uk/terms/447468>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D016729>
p:direct-normalized/P592 <http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL1201199>
p:direct-normalized/P6366 <https://makg.org/entity/2779093440>
p:direct-normalized/P661 <http://rdf.chemspider.com/571356>
p:direct-normalized/P662 <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID657181>
p:direct-normalized/P665 <http://www.kegg.jp/entry/C07612>
<http://www.kegg.jp/entry/D08113>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D06.472.699.327.740.320.400>
<http://id.nlm.nih.gov/mesh/D12.644.400.400.740.320.400>
<http://id.nlm.nih.gov/mesh/D12.644.456.460.480>
<http://id.nlm.nih.gov/mesh/D12.644.548.365.740.320.400>
<http://id.nlm.nih.gov/mesh/D12.776.631.650.405.740.320.400>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_6427>
wdt:P10245 "a685040"
wdt:P10283 "C2779093440"
wdt:P11089 "251067"
wdt:P11143 "Leuprorelin"
wdt:P11198 "1559"
wdt:P11199 "PD047224"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Leuprorelin.svg>
wdt:P129 Gonadotropin releasing hormone receptor
wdt:P1552 biopharmaceutical
wdt:P1579 "741818"
wdt:P2017 "CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6"
wdt:P2057 "HMDB0041916"
wdt:P2062 "6518"
wdt:P2067 1208.645462^^xsd:decimal
wdt:P2115 "N0000147889"
wdt:P2175 breast cancer
ovarian cancer
infertility
prostate cancer
endometrial carcinoma
endometriosis
precocious puberty
leiomyoma
prostatic hypertrophy
wdt:P2275 "leuprorelin"@en
wdt:P231 "53714-56-0"
wdt:P232 "633-395-9"
wdt:P233 "CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6"
wdt:P234 "InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1"
wdt:P235 "GFIJNRVAKGFPGQ-LIJARHBVSA-N"
wdt:P2566 "100.161.466"
wdt:P267 "L02AE02"
wdt:P274 "C₅₉H₈₄N₁₆O₁₂"
wdt:P279 synthetic peptide
wdt:P2840 "377526"
wdt:P2868 WHO essential medicines
female fertility agents
hormonal antineoplastic agent
wdt:P2877 "4585"
wdt:P2892 "C0085272"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID50872411"
wdt:P3345 "42375"
wdt:P366 medication
wdt:P373 "Leuprorelin"
wdt:P3780 Lupron Depot
wdt:P4250 0.134^^xsd:decimal
1.0^^xsd:decimal
wdt:P4527 "447468"
wdt:P486 "D016729"
wdt:P592 "CHEMBL1201199"
wdt:P595 "1175"
wdt:P6366 "2779093440"
wdt:P646 "/m/04trb9"
wdt:P652 "EFY6W0M8TG"
wdt:P661 "571356"
wdt:P662 "657181"
wdt:P665 "C07612"
"D08113"
wdt:P672 "D06.472.699.327.740.320.400"
"D12.644.400.400.740.320.400"
"D12.644.456.460.480"
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"D12.776.631.650.405.740.320.400"
wdt:P683 "6427"
wdt:P715 "DB00007"
wdt:P7830 "Leuprolide"
wdt:P8026 LiverTox toxicity likelihood category E
wdt:P8494 "DTXCID00820063"
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