SHMARQL

droxidopa

<http://www.wikidata.org/entity/Q907853>

a synthetic amino acid precursor acting as a prodrug to the neurotransmitter norepinephrine
rdfs:label
"droxidopa"@en
skos:altLabel
"(-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid"@en
"(2S,3R)-3,4-dihydroxy-phenylserine"@en
"DOPS"@en
"Droxidopa"@en
"Droxydopa"@en
"L-DOPS"@en
"L-Dihydroxyphenylserine"@en
"L-Threodops"@en
"L-threo-dihydroxyphenylserine"@en
"Northera®"@en
"SM 5688"@en
"SM-5688"@en
"threo-Dopaserine"@en
schema:description
"a synthetic amino acid precursor acting as a prodrug to the neurotransmitter norepinephrine"@en
schema:dateModified "2026-11-04T14:57:31+00:00"^^xsd:dateTime
schema:version 2564730075
wikibase:identifiers 36
wikibase:sitelinks 14
wikibase:statements 55
p:P10245 wd:statement/Q907853-42cba842-4ef5-1b55-b6ea-5a1f8453bad6
p:P11143 wd:statement/Q907853-9874DDA3-4A69-4A0E-8950-7210311C5640
p:P11198 wd:statement/Q907853-ABB71551-F259-41E9-8E2E-3D095D2E9696
p:P11199 wd:statement/Q907853-439DE200-99CD-4B04-9695-B1E95B2716F1
p:P117 wd:statement/Q907853-1e30e68f-4689-a4e9-9415-4f29991e8e1a
wd:statement/Q907853-C2F9BCC8-0713-4F99-9200-BC5269A8C159
p:P1579 wd:statement/Q907853-7B83C3E2-4150-4E97-AC51-FC47EF7AFE0E
p:P1748 wd:statement/Q907853-69C50DDB-912D-48A1-BC0A-18E00E58EE82
p:P2017 wd:statement/Q907853-071E326C-A06E-45E1-A98F-83244CBD0981
p:P2057 wd:statement/Q907853-9A34752B-2184-48F2-95CC-AF26F7616A6C
p:P2067 wd:statement/Q907853-D144A868-4241-4CD3-8FA3-9CA7900FE7BD
p:P2115 wd:statement/Q907853-23516A00-3D55-461E-B55C-139685CFECD3
p:P2175 wd:statement/Q907853-417417A3-30CE-4064-8C38-9C918671DD0D
wd:statement/Q907853-54AADE4B-6A6C-4E52-B561-36DC87D5C332
wd:statement/Q907853-E215E43F-3899-4E0D-B479-E43A0FF7D1B2
p:P2275 wd:statement/Q907853-BFED7271-3EC2-4A5D-A594-54C2BF22325C
p:P231 wd:statement/Q907853-F62AE5E3-8ABB-4175-A6F9-03297AD65FEC
p:P232 wd:statement/Q907853-40E5F2FE-7E29-4350-8884-C9EB88F9F6F7
p:P233 wd:statement/Q907853-54CD047F-A5C7-4AF0-A802-2F9071ABCFC1
p:P234 wd:statement/Q907853-8F9CD939-1D16-4581-9DA2-62C38236A062
p:P235 wd:statement/Q907853-E62D7057-FFF3-4FA3-8128-14045F829B06
p:P2566 wd:statement/Q907853-13572468-2468-1357-eca9-bdf024681357
p:P267 wd:statement/Q907853-E07657E2-B280-44C9-81EB-7DE6A61329D8
p:P274 wd:statement/Q907853-EE5F4A72-1035-4D19-B347-F7A905522E2D
p:P279 wd:statement/Q907853-05FCAD25-3163-4EEF-B937-6B3855C40634
p:P2868 wd:statement/Q907853-4E7D2742-6584-4616-94D7-FA22273850E9
p:P2877 wd:statement/Q907853-2424A548-8205-40A7-8484-367ACB21FB23
wd:statement/Q907853-D6ED177D-A4B0-4BD6-B394-0E341760AA0E
p:P31 wd:statement/Q907853-E5BBE73C-AB52-4EA9-8D8A-7C8CE2DAA0BD
p:P3117 wd:statement/Q907853-6722CD4A-9C81-4DDE-A266-F01C0AF3B605
p:P3345 wd:statement/Q907853-193F6FCB-B621-4EB9-9A98-CD7AB016A321
p:P3493 wd:statement/Q907853-F0CDD230-4F9C-481F-8CF7-3BB7942910F3
p:P366 wd:statement/Q907853-DE9E6BED-3A81-4AD1-97E3-9D07E574AFD7
p:P373 wd:statement/Q907853-75D305FD-22B8-46C7-BD0A-10CD3F14998F
p:P3780 wd:statement/Q907853-D1466274-FF8D-41D8-A8B9-8CF19AD133C3
p:P4235 wd:statement/Q907853-EF4F27C0-439F-41B3-8DAE-4F20B7101A45
p:P486 wd:statement/Q907853-89A46450-AAA3-4A90-9CFE-E990E439350D
p:P592 wd:statement/Q907853-5DDA9E14-6135-4149-B962-7F74F54CB387
p:P595 wd:statement/Q907853-A4C6909C-0A5D-487C-A09C-E6E1EDE60CD4
p:P6366 wd:statement/Q907853-D5E3CF96-AD99-47C9-B527-4CD64F6561C4
p:P646 wd:statement/Q907853-35F7CCEC-D2AD-47EC-A617-7FF4E094EED1
p:P652 wd:statement/Q907853-79E19357-F8B5-4F7B-8E7B-73C6103BAF93
wd:statement/Q907853-AAAD67D5-4873-43DF-B540-D458CC2B3084
p:P661 wd:statement/Q907853-D9B9A6FA-1F16-4AED-95C8-49B44D60EDE9
p:P662 wd:statement/Q907853-B9834CBE-6E9D-4625-ADFD-8281CB5081C6
wd:statement/Q907853-FA21E336-8D41-4C0B-898E-4DB9669CC9BE
p:P665 wd:statement/Q907853-758BECA1-DEDF-4C28-96F3-1409657E3658
p:P672 wd:statement/Q907853-4f8c974e-43f0-c549-d524-666e8c76b227
wd:statement/Q907853-6b343da7-4742-c3f2-82ca-807c7857ab0d
wd:statement/Q907853-a338d9d8-407b-6119-bbc5-c4a46e350f9d
p:P683 wd:statement/Q907853-C559E9FB-22AE-4F90-8C47-4827E2D30701
p:P715 wd:statement/Q907853-46ACD087-0087-4CAC-8614-2BEE12309C5E
p:P7830 wd:statement/Q907853-D1206049-C42A-4162-9003-0BBCED9B7CA9
p:P8026 wd:statement/Q907853-39925356-B617-43DE-8CE8-03A3C4322FC9
p:P8494 wd:statement/Q907853-7D3DFFDD-FC24-4AD8-BF21-F4FF4405B803
p:direct-normalized/P2115 <http://purl.bioontology.org/ontology/NDFRT/N0000190929>
p:direct-normalized/P486 <http://id.nlm.nih.gov/mesh/D015103>
p:direct-normalized/P592 <http://rdf.ebi.ac.uk/resource/chembl/molecule/CHEMBL2103827>
p:direct-normalized/P6366 <https://makg.org/entity/2779218525>
p:direct-normalized/P661 <http://rdf.chemspider.com/83927>
p:direct-normalized/P662 <http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6989215>
<http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID92974>
p:direct-normalized/P665 <http://www.kegg.jp/entry/D01277>
p:direct-normalized/P672 <http://id.nlm.nih.gov/mesh/D02.092.311.830.220>
<http://id.nlm.nih.gov/mesh/D02.455.426.559.389.657.166.175.830.220>
<http://id.nlm.nih.gov/mesh/D12.125.154.800.875>
p:direct-normalized/P683 <http://purl.obolibrary.org/obo/CHEBI_31524>
wdt:P10245 "a614025"
wdt:P11143 "Droxidopa"
wdt:P11198 "971"
wdt:P11199 "PD014696"
wdt:P117 <http://commons.wikimedia.org/wiki/Special:FilePath/Droxidopa.svg>
<http://commons.wikimedia.org/wiki/Special:FilePath/L-DOPS.svg>
wdt:P1579 "7112431"
wdt:P1748 "C73266"
wdt:P2017 "N[C@@H]([C@H](O)C1=CC=C(O)C(O)=C1)C(O)=O"
wdt:P2057 "HMDB0015627"
wdt:P2067 213.063722^^xsd:decimal
wdt:P2115 "N0000190929"
wdt:P2175 Parkinson's disease
multiple system atrophy
neurodegeneration
wdt:P2275 "droxidopa"@en
wdt:P231 "23651-95-8"
wdt:P232 "688-528-3"
wdt:P233 "C1=CC(=C(C=C1C(C(C(=O)O)N)O)O)O"
wdt:P234 "InChI=1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1"
wdt:P235 "QXWYKJLNLSIPIN-JGVFFNPUSA-N"
wdt:P2566 "100.215.254"
wdt:P267 "C01CA27"
wdt:P274 "C₉H₁₁NO₅"
wdt:P279 catecholamine
wdt:P2868 antiparkinson
wdt:P2877 "134299"
"29388035"
wdt:P31 type of chemical entity
wdt:P3117 "DTXSID6046422"
wdt:P3345 "1489913"
wdt:P3493 boxed warning
wdt:P366 medication
wdt:P373 "Droxidopa"
wdt:P3780 Northera
wdt:P4235 "droxidopa"
wdt:P486 "D015103"
wdt:P592 "CHEMBL2103827"
wdt:P595 "7391"
wdt:P6366 "2779218525"
wdt:P646 "/m/047drd2"
wdt:P652 "24A0V01WKS"
"J7A92W69L7"
wdt:P661 "83927"
wdt:P662 "6989215"
"92974"
wdt:P665 "D01277"
wdt:P672 "D02.092.311.830.220"
"D02.455.426.559.389.657.166.175.830.220"
"D12.125.154.800.875"
wdt:P683 "31524"
wdt:P715 "DB06262"
wdt:P7830 "Droxidopa"
wdt:P8026 LiverTox toxicity likelihood category E
wdt:P8494 "DTXCID4026422"
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data from SPARQL profile: Wikidata